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Metabolomics in Natural Products Research (천연물 연구에서의 메타볼로믹스)

  • Chan Seo;Tae-Su Kim;Bo-Ram Kim;Su Hui Seong;Jin-Ho Kim;Ha-Nul Lee;Sua Im;Jung Eun Kim;Ji Min Jung;Jin-Woo Jeong
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.16-16
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    • 2023
  • Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism) under a given set of conditions. Metabolomics has its roots in early metabolite profiling studies but is now a rapidly expanding area of scientific research in its own right. In this study, the applications of metabolomics in natural product studies are explored. Ginseng is a well-known herbal medicine and has various pharmacological effects, which include antiaging, anticancer, antifatigue, memory enhancing, immunomodulatory, and stress reducing effects. Metabolomic analysis of organic acids has not been performed for evaluation whether ginseng has been cultivated using conventional or environmental-friendly farming methods. In this study, profiling analysis was conducted for organic acids (OAs) in ginseng roots produced using conventional or environmentfriendly farming methods at five locations in each of five regions. In OA profiles, lactic acid was the most abundant OA in all regions, with the exception for environmentally friendly farmed ginseng in two of the five regions, in which glycolic acid was most abundant OA. OA profiles in all regions showed isocitric acid levels were increased by environment-friendly cultivation, which suggests metabolic differences associated from farming method, and that isocitric acid might be a useful discriminatory biomarker of environmental-friendly and conventional cultivation. The results of the present study suggest metabolomic studies of OAs in ginseng roots might be useful for monitoring whether ginseng has been cultivated using conventional or environmentally friendly farming methods.

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Application of Hamilton variational principle for vibration of fluid filled structure

  • Khaled Mohamed Khedher;Muzamal Hussain;Rizwan Munir;Saleh Alsulamy;Ayed Eid Alluqmani
    • Advances in nano research
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    • v.15 no.5
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    • pp.401-410
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    • 2023
  • Vibration investigation of fluid-filled three layered cylindrical shells is studied here. A cylindrical shell is immersed in a fluid which is a non-viscous one. Shell motion equations are framed first order shell theory due to Love. These equations are partial differential equations which are usually solved by approximate technique. Robust and efficient techniques are favored to get precise results. Employment of the wave propagation approach procedure gives birth to the shell frequency equation. Use of acoustic wave equation is done to incorporate the sound pressure produced in a fluid. Hankel's functions of second kind designate the fluid influence. Mathematically the integral form of the Lagrange energy functional is converted into a set of three partial differential equations. It is also exhibited that the effect of frequencies is investigated by varying the different layers with constituent material. The coupled frequencies changes with these layers according to the material formation of fluid-filled FG-CSs. Throughout the computation, it is observed that the frequency behavior for the boundary conditions follow as; clamped-clamped (C-C), simply supported-simply supported (SS-SS) frequency curves are higher than that of clamped-simply (C-S) curves. Expressions for modal displacement functions, the three unknown functions are supposed in such way that the axial, circumferential and time variables are separated by the product method. Computer software MATLAB codes are used to solve the frequency equation for extracting vibrations of fluid-filled.

Reproduction of 3D Virtual Wear of Sleeve-expanded Power Shoulder Jacket (소매확장 파워숄더 재킷의 3D 가상착의 재현)

  • Jeongah Park;Jeongran Lee
    • Fashion & Textile Research Journal
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    • v.25 no.5
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    • pp.593-602
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    • 2023
  • This study aimed to facilitate the use of virtual technologies such as sewing, appearance, and material expression in 3D virtual wear programs. For product production and education, we expounded how to express the shoulder shape and silhouette of sleeve-expanded power shoulder jackets. Two designs of sleeve-expanded power shoulder jackets were selected, and virtual jackets were produced using a virtual avatar based on the body dimensions of female subjects in their 20s. The essential purpose of a 3D virtual power shoulder jacket is to express the shoulder angle rise and shoulder width, which are much wider than the avatar's shoulder. Therefore, the virtual pad values were adjusted for the collision and rendering of each thickness. In addition, the position and angle of the virtual pads were controlled through simulation. Appearance similarity was evaluated using photographic data and the virtual jackets. For the set-in sleeve virtual power shoulder jacket, the wrinkle expressions of the torso and sleeve were rated as moderate, and material expression was slightly insufficient. The similarity of some ease and width items of the torso was tightly expressed, and the overall appearance, positions of lines, and details of jackets were rated high, especially at the neck and sleeve shapes. In the case of the kimono virtual power shoulder jacket, the expressions of the torso wrinkles and buttons were slightly lower; however, the overall similarity, basic lines, ease, shoulder and neck details, and material expression of the virtual jackets were highly evaluated.

Sensitivity Evaluation and Approximate Optimization Analysis for Structure Design of Module Hull Type Trimaran Pontoon Boat (모듈 선체형 삼동 폰툰 보트의 구조설계 민감도 평가와 근사 최적화 해석)

  • Bo-Youp Choi;Chang-Ryeon Son;Joon-Sik Son;Min-Ho Park;Chang-Yong Song
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.6_3
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    • pp.1279-1288
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    • 2023
  • Recently, domestic leisure boats have been actively researching eco-friendly product development to enter the global market. Since the hulls of existing leisure boats are mainly made of fiber reinforced plastic (FRP) or aluminum, design techniques for securing structural safety by applying related materials have been mainly studied. In this study, an initial structural design safety assessment of a trimaran pontoon leisure boat with a modular hull structure and eco-friendly high-density polyethylene (HDPE) material was conducted, and sensitivity evaluation and optimization analysis for lightweight design were performed. The initial structural design safety assessment was carried out by creating a finite element analysis model and applying the loading conditions specified in the ship classification regulation to check whether the specified allowable stresses are satisfied. For the sensitivity evaluation, the influence of stress and weight of each hull structural member was evaluated using the orthogonal array design of experiments method, and an approximate model based on the response surface method was generated using the results of the design of experiments. The optimization analysis set the thickness of the hull structural members as the design variable and considered the optimal design formulation to minimize the weight while satisfying the allowable stress. The algorithm of the optimization analysis applied the Gradient-population Based Optimizer (GBO) to improve the accuracy of the optimal solution convergence while reducing the numerical cost. Through this study, the optimal design of a newly developed eco-friendly trimaran pontoon leisure boat with a weight reduction of 10% was presented.

The Impact of Environmental Concern, Environmental Knowledge, and Consumer Value on Purchase Intention and Behavior of Up-cycled Products (환경관심, 환경지식, 소비가치가 업사이클 제품의 구매의도 및 구매행동에 미치는 영향)

  • Chan Ho Jeon;Sang Hyeok Park;Seung Hee Oh
    • Journal of Information Technology Applications and Management
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    • v.31 no.1
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    • pp.123-138
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    • 2024
  • With the increase in online shopping and delivery food consumption since the pandemic, solving environmental problems caused by single-use packaging has become an important issue. 'Upcycling' is a combination of 'Upgrade' and 'Recycle', and it is the rebirth of obsolete or discarded objects by adding new value to them, and there are currently various upcycled products on the market. In order to activate upcycling, consumers' awareness of the environment and their values for consumption are very important. This study aims to investigate the influence of students' environmental concern, environmental experience, and consumption value on their purchase intention of upcycled products. Based on the results of previous studies on environmental concern, environmental experience, and consumption value, hypotheses were set, and a survey was conducted among university students nationwide to test the hypotheses. The results of this study are as follows First, environmental concern has a significant positive effect on purchase intention of upcycled products. It can be seen that the more environmental concerns such as global warming and waste disposal problems increase, the more positive attitudes toward upcycled products increase. Second, the research hypothesis that environmental knowledge will have a positive effect on the purchase intention of upcycled products is rejected. It was found that environmental knowledge is acquired through environmental education and many SNS, but it does not have a direct effect on the purchase intention of upcycled products. Third, it was found that the consumption value of college students has a positive effect on the purchase intention of upcycled products by increasing their positive perception of upcycled products. Fourth, college students' purchase intention of upcycled products has a positive effect on their behavioral intention to purchase upcycled products. The results of the study provide implications for relevant organizations such as universities and companies to effectively design upcycling-related education. It is also expected to have a positive impact on the use of upcycled products by providing basic information on the characteristics of consumers who purchase upcycled products.

An advanced machine learning technique to predict compressive strength of green concrete incorporating waste foundry sand

  • Danial Jahed Armaghani;Haleh Rasekh;Panagiotis G. Asteris
    • Computers and Concrete
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    • v.33 no.1
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    • pp.77-90
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    • 2024
  • Waste foundry sand (WFS) is the waste product that cause environmental hazards. WFS can be used as a partial replacement of cement or fine aggregates in concrete. A database comprising 234 compressive strength tests of concrete fabricated with WFS is used. To construct the machine learning-based prediction models, the water-to-cement ratio, WFS replacement percentage, WFS-to-cement content ratio, and fineness modulus of WFS were considered as the model's inputs, and the compressive strength of concrete is set as the model's output. A base extreme gradient boosting (XGBoost) model together with two hybrid XGBoost models mixed with the tunicate swarm algorithm (TSA) and the salp swarm algorithm (SSA) were applied. The role of TSA and SSA is to identify the optimum values of XGBoost hyperparameters to obtain the higher performance. The results of these hybrid techniques were compared with the results of the base XGBoost model in order to investigate and justify the implementation of optimisation algorithms. The results showed that the hybrid XGBoost models are faster and more accurate compared to the base XGBoost technique. The XGBoost-SSA model shows superior performance compared to previously published works in the literature, offering a reduced system error rate. Although the WFS-to-cement ratio is significant, the WFS replacement percentage has a smaller influence on the compressive strength of concrete. To improve the compressive strength of concrete fabricated with WFS, the simultaneous consideration of the water-to-cement ratio and fineness modulus of WFS is recommended.

Vibrational Modes of Pyeongeong (편경의 진동모드 분석)

  • Yoo June-Hee
    • The Journal of the Acoustical Society of Korea
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    • v.25 no.3
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    • pp.121-128
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    • 2006
  • Korean pyeongyeong, a set of sixteen L-shape chime stones covering one and one third octaves, is a standard instrument in the Korean traditional court music. We analyze the vibrational mode frequencies in a pyeongyeong replica which is played at the National Center for Korean Traditional Performance Arts and pyeongyeong remains which are exhibited at King Sejong Memorial Museum. The modal shapes on the Whangjong, the 1st stone and Cheonghyurjong, the 16th stone mapped by scanning accelerometer, TV holography and STAR system. The nominal frequencies in pyeongyeong replica at the National Center for Korean Traditional Performance Arts increase linearly with the thickness of the stones and the tones are tuned in line with the musical scale of Sambunsonik. The sexagenary cycles on the pyeongyeong remains at King Sejong Memorial. which show the Year of product indirectly, are different each other and the tones are not tuned in scale. The relative frequency ratios of each modes on stones differ more than just-noticeable differences from those on the pyeongyeong replica. Modal shapes are same for the two stones regardless of the thickness.

The Impact of Virtual Influencers' Characteristics on Purchase Intentions Toward Fashion Products: Focusing on the Mediating Effect of Mimetic Desire (버추얼 인플루언서의 특성이 패션제품 구매의도에 미치는 영향: 모방욕구의 매개효과를 중심으로)

  • Haram Shin;Misun Yum
    • Fashion & Textile Research Journal
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    • v.26 no.1
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    • pp.1-14
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    • 2024
  • Virtual influencers, who are emerging as new players in digital marketing, impact consumers' purchase intentions. They promote positive perceptions and mimetic consumption of specific brands or products through interactions with followers. Therefore, this study aims to examine the effect of the characteristics of virtual influencers on the purchase intention for fashion products through the consumers' mimetic desire. As characteristics of virtual influencers, five factors were set: reality, attractiveness, professionalism, trustworthiness, and curiosity. Data for analysis were collected through an online questionnaire from the 8th to the 15th of August 2023, and 268 data points in total were analyzed using SPSS and Process Macro 4.3. The results of the study showed that the characteristics of virtual influencers all positively affected mimetic desire and purchase intention for fashion products. Moreover, it was found that mimetic desire has a mediating effect between the five characteristics of virtual influencers and the purchase intention for fashion products. Mimetic desire fully mediates the relationship between reality and the intention to purchase fashion products, and partially mediates the relationship between attractiveness, professionalism, trustworthiness, and curiosity and the purchase intention for fashion products. These findings further enhance the understanding of the relationship between virtual influencers and consumer behavior and identify the relationship between virtual influencers, mimetic desire, and fashion product purchase intentions. Consequently, leveraging virtual influencers strategically in digital marketing, the fashion industry can amplify positive brand perceptions, drive consumer engagement, and ultimately foster increased purchase intent.

Implications of Deep Nitrite in the Ulleung Basin (울릉 분지 저층수의 아질산염)

  • Lee, Tong-Sup;Kim, Il-Nam;Kang, Dong-Jin;Kim, Dong-Seon
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.12 no.3
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    • pp.239-243
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    • 2007
  • Presence of bottom water nitrite in the Ulleung Basin was remarkable because it is totally unexpected phenomenon at such an oxygen-rich environment. Yet no scientific explanation was set forward. Of several plausible explanations, following the Ockham's suggestion, a leaching of nitrite as an intermediate product of denitrification in the top sediment at the slope is most agreeable to given environmental settings. There seems no complementary process to make up the loss of N in the Ulleung Basin, which seems contribute to the characteristically low N:P ratio in the deep waters. If warming proceeds that weakens the thermohaline circulation, a current biological pump may stall and the phytoplankton assemblage might replaced drastically. If so this will pause an utmost challenge to the ecosystem of the East/Japan Sea. Still there remains a contradictory sedimentary signature that requests further explanation regarding the N (or organic C)-cycle such as extraordinarily high organic carbon content despite abundant oxidants in the overlying waters.

Critical Analyses of '2nd Science Inquiry Experiment Contest' (과학탐구 실험대회의 문제점 분석)

  • Paik, Seoung-Hey
    • Journal of The Korean Association For Science Education
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    • v.15 no.2
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    • pp.173-184
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    • 1995
  • The purpose of this study was to analyse the problems of 'Science Inquiry Experiment Contest(SIEC)' which was one of 8 programs of 'The 2nd Student Science Inquiry Olympic Meet(SSIOM)'. The results and conclusions of this study were as follows: 1. It needs to reconsider the role of practical work within science experiment because practical work skills form one of the mainstays in current science. But the assessment of students' laboratory skills in the contest was made little account of. It is necessary to remind of what it means to be 'good at science'. There are two aspects: knowing and doing. Both are important and, in certain respects, quite distinct. Doing science is more of a craft activity, relying more on craft skill and tacit knowledge than on the conscious application of explicit knowledge. Doing science is also divided into two aspects, 'process' and 'skill' by many science educators. 2. The report's and checklist's assessment items were overlapped. Therefore it was suggested that the checklist assessment items were set limit to the students' acts which can't be found in reports. It is important to identify those activities which produce a permanent assessable product, and those which do not. Skills connected with recording and reporting are likely to produce permanent evidence which can be evaluated after the experiment. Those connected with manipulative skills involving processes are more ephemeral and need to be assessed as they occur. The division of student's experimental skills will contribute to the accurate assess of student's scientific inquiry experimental ability. 3. There was a wide difference among the scores of one participant recorded by three evaluators. This means that there was no concrete discussion among the evaluators before the contest. Despite the items of the checklists were set by preparers of the contest experiments, the concrete discussions before the contest were necessary because students' experimental acts were very diverse. There is a variety of scientific skills. So it is necessary to assess the performance of individual students in a range of skills. But the most of the difficulties in the assessment of skills arise from the interaction between measurement and the use. To overcome the difficulties, not only must the mark needed for each skill be recorded, something which all examination groups obviously need, but also a description of the work that the student did when the skill was assessed must also be given, and not all groups need this. Fuller details must also be available for the purposes of moderation. This is a requirement for all students that there must be provision for samples of any end-product or other tangible form of evidence of candidates' work to be submitted for inspection. This is rather important if one is to be as fair as possible to students because, not only can this work be made available to moderators if necessary, but also it can be used to help in arriving at common standards among several evaluators, and in ensuring consistent standards from one evaluator over the assessment period. This need arises because there are problems associated with assessing different students on the same skill in different activities. 4. Most of the students' reports were assessed intuitively by the evaluators despite the assessment items were established concretely by preparers of the experiment. This result means that the evaluators were new to grasp the essence of the established assessment items of the experiment report and that the students' assessment scores were short of objectivity. Lastly, there are suggestions from the results and the conclusions. The students' experimental acts which were difficult to observe because they occur in a flash and which can be easily imitated should be excluded from the assessment items. Evaluators are likely to miss the time to observe the acts, and the students who are assessed later have more opportunity to practise the skill which is being assessed. It is necessary to be aware of these problems and try to reduce their influence or remove them. The skills and processes analysis has made a very useful checklist for scientific inquiry experiment assessment. But in itself it is of little value. It must be seen alongside the other vital attributes needed in the making of a good scientist, the affective aspects of commitment and confidence, the personal insights which come both through formal and informal learning, and the tacit knowledge that comes through experience, both structured and acquired in play. These four aspects must be continually interacting, in a flexible and individualistic way, throughout the scientific education of students. An increasing ability to be good at science, to be good at doing investigational practical work, will be gained through continually, successively, but often unpredictably, developing more experience, developing more insights, developing more skills, and producing more confidence and commitment.

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