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The Processed Radish Extract Melanogenesis in Humans and Induces Anti-Photoaging Effects in Ultraviolet B-Induced Hairless Mouse Model

  • Kim, Hyun-Kyoung
    • International Journal of Advanced Culture Technology
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    • v.7 no.4
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    • pp.125-136
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    • 2019
  • The radish skin and radish greens are an edible part of the radish. But they are removed before eating the radish and used as a byproduct or an animal feed material because of their tough and rough texture. Melanin is a pigment that gives colour to our skin. But increased production of melanin can turn into benign or malignant tumours. These days due to global warming, the amount of Ultra violet (UVB) rays has been extensively increased with sunlight. Due to this, a phenomenon called exogenous photo aging is widely observed for all skin colour and types. As a result of this phenomenon, a set of enzymes called matrix metalloproteinases (MMP's) that serves as degradation enzymes for extracellular matrix proteins mainly collagen is increased, causing depletion in collagen and resulting in early wrinkles formation. Therefore in our study we used the murine melanoma cell line B16/F10 to study the melanogenesis inhibition by Heated radish extract (HRE) in vitro and we used HRM-2 hair less mice exposed to artificial UVB for checking the efficacy of Heated radish extract in vivo. Furthermore, we prepared a 3% Heated radish extract (HRE) cream and checked its effects on human skin. Our results have clearly demonstrated that Heated radish extract (HRE) have potently suppressed the tyrosinase activity and melanin production in B16/F10 cells. It had also reduced the expression of components involved in melanin production pathway both transcriptionally and transitionally. In in vivo studies, HRE had potently suppressed the expression of MMP's and reduced the wrinkle formation and inhibited collagen degradation. Moreover, on human skin, ginseng cream increased the resilience, skin moisture and enhanced the skin tone. Therefore in light of these findings, we conclude that HRE is an excellent skin whitening and antiaging product.

A Study about Construction of Sasang Constitutional Nursing Theory: On the focus 『Dongyi Soose Bowon Sasang Chobongyun』 (체질적 간호 이론 정립을 위한 연구 『동의수세보원사상초본권(東醫壽世保元四象草本卷 )』 을 중심으로)

  • Yoo, Jung-Hee;Lee, Eui-Ju;Song, Il-Byung;Koh, Byung-Hee;Lee, Soo-Kyung;Lee, Hyang-Yeon
    • Journal of Sasang Constitutional Medicine
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    • v.16 no.2
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    • pp.71-83
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    • 2004
  • 1. Objectives The purpose of nursing is to promote health and well-being for all persons. It is connected with Sasang Constitution theory have regard for viewpoint by other's a special quality & individual difference. A nursing is helping behavior to recover health, disease protection & self care ability through health education. There is need for Oriental nursing research continually. 2. Methods This study attempted to develop a fundamental nursing theory for Sasang Constitution on the focus "Dongyi Soose Bowon Sasang Chobongyun". Because the book is important to understand Lee Je-ma's early medical mind and thinking. 3. Results and Conclusions The Sasang Constitution theory lay great emphasis upon health caring medicine to promote health according to self Constitution at normal times, preventive medicine to manage byself body and mind in ordinary times. The way of Sasang Constitutional Nursing Theory is expected to set up a landmark stone in Korean nursing. It is also can product a new nursing theory. In view of 'Nature and Order' is explained inborned general human being who were gifted from nature. On the other hand, in view of 'Knowledge and Deed' based on Constitutions are explained autonomical human being. There are depend on independant control and make efforts themselves or not. It have a connected in four paradigm (human- environment-health- nursing) of nursing theory. The history taking stage claim caring of sick-people before. The ways of assesment for sick-people have to know a process of illness.

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A Study of Web Application Security Quality Architecture Management Process referenced ISO/IEC9000 Model (ISO/IEC9000모델을 참조한 웹 애플리케이션 보안품질 관리체계 설계)

  • Kim, Jeom-Goo;Noh, Si-Choon;Lee, Do-Hyeon
    • Convergence Security Journal
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    • v.12 no.3
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    • pp.11-17
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    • 2012
  • According to ISO/IEC 9000, quality to satisfy users' requirements when using the product or service is defined as the characteristics of the synthesized concept. Secure web application coding information systems with the reliability and quality of service is one of the determining factor. Secure coding in order to achieve the quality based on the model is necessary. The reason is that the security is in quality properties in the range of non-functional requirements that necessitates. Secure coding for the design of quality systems based on the quality of the definition of quality attributes, quality requirements, quality attribute scenarios are defined, and must be set. To this end, referring to IEEE 1061 quality model for web application, quality model structure is developed. Secure web application architecture design is composed of coding quality of the model systems, web applications draw interest to stakeholders, decision drivers secure coding architecture, quality attributes, eliciting quality requirements of the security settings, creating web application architecture descriptions and security framework.

Research on Brand Identification in the Airline Industry (항공 산업에서의 브랜드 동일시 연구)

  • Ko, Seon-Hee
    • Journal of the Korea Convergence Society
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    • v.11 no.3
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    • pp.219-226
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    • 2020
  • This study set the research model to analyze the effect of customer value on brand identification and loyalty using customers of K Airline. Based on previous researches, this study extracted variables, and built a structural equation model to examine the relationship among variables. The findings of empirical research are as follows. First, it was found that functional value and emotional value of customer value have significant effect on brand identification. Thus, hypothesis 1 was accepted. Second, customers seek emotional aspect in choosing a product or a service. That is, by using an airline brand which they think is identical with their image, value, or lifestyle, they pursue brand identification with the airline. Third, given that functional value and emotional value of customer value do not affect brand loyalty, we can know that customer value strengthens brand loyalty through brand identification. To boost brand loyalty, K Airline needs to pay attention to raise brand identification of customers with consideration of other mediating variables.

Improvement of computer keyboard design through behavioral analysis (Focused on the characteristics of Korean Alphabet and its use) (사용행태 분석에 의한 컴퓨터 키보드 디자인 개선 -한글의 특성 및 사용행태를 중심으로-)

  • 변재형
    • Archives of design research
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    • v.15 no.3
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    • pp.241-248
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    • 2002
  • Researches of Hangul automation have been focused mainly on the set of character system. But, practical problem of using the Korean standard keyboard system of two sets is increment of errors and fatigue due to frequent use of shift keys. The author formulate a hypothesis as follows to solve the problem. 'Changing location and design of shift keys can reduce errors in typing Korean by avoiding interferences with other keys when pressing shift keys.' This study verify the hypothesis by the analysis of experiments using improved keyboard prototypes which have changed layout and design of shift keys. On the result, change of shift key location causes confusion to experienced user. But, while keeping its location, removing other keys at the bottom row and magnifying size of shift keys decrease errors in typing by avoiding interferences. And, the efficiency of typing in Korean is increased, too, because there is not any influence on typing speed. This study focuses on layout and design of shift keys only, but further study for entire layout of keyboard including alternative location of other function keys is needed to improve general usability.

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The Effects of Servitization Acceptance on Performance through Mediation of Service Process & ICT Competency (서비스화 수용활동이 서비스화 추진성과에 미치는 영향 : 서비스 프로세스 역량과 ICT 역량의 매개적 역할)

  • Yoon, Yong;Kim, Youn Sung
    • Journal of Information Technology Services
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    • v.15 no.4
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    • pp.111-123
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    • 2016
  • The purpose if this study was to find and investigate effective mediation factors influencing performance of servitization through servitization acceptance activities by means of empirical results. According to the previous researches, two main mediation factors which were related with servitization competencies such as ICT competency of servitization and competency of servitization process were distinguished from lots of competencies which are relying on servitization process. Using a 373 sample data investigated from CEOs, directors and managers of small and medium sized firms in Korea, the structured mediation model was proposed. The measurement for the each variable was accepted for this study when the respondents were revealed to understand the servitization concepts which explained especially company's business moving towards the service specific gravity from selling existing products. The measurement for the each variable reflected that respondents were participating in any sort of servitization type or had intension to be involved with any servitization categories. The mediation hypotheses were tested in the way of analytical measures with the result of strong reliability. According to analysis, two mediators showed positive mediation role and statistically adopted between servitization acceptance activities and servitization performance in the 99% significant level. We confirmed that ICT competency of servitization and competency of servitization process were in the role of positive mediation between servitization acceptance activities and performance of servitization. The total of indirect effects were 0.2546 to support each mediation hypotheses. Tested two mediators were not on the same level. The most affecting mediation element on servitization performance was appeared as competency of servitization process. With the result of this study, we expect that the small and medium sized companies might have servitization business strategies including proper service competencies and mediators through acceptance activities to obtain suitable performance. According to the analysis, Companies which consider product-servitization need to set strategies to reinforce above two competencies.

A Study on Domestic and Foreign Research Movement of the Eco-tourism Certification/Designation System and Its Application in Korea (국내·외 생태관광 인증/지정제도 동향 및 국내 제도 도입 방안)

  • Choi, Hee-Sun;Kim, Hyun-Ae
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.1
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    • pp.73-87
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    • 2012
  • This study was conducted to provide sustainable measures for conservation and management to protect valuable natural/ecological resources, offer differentiated quality assurance services for eco-tourism products, and explore measures for eco-tourism certification/designation systems. To achieve its goals, the study discussed domestic and overseas trends and literatures that concern eco-tourism certification/designation system and investigated case studies that were presently operational. A group of experts and a group of non-experts were surveyed separatedly to investigate the awareness of the national eco-tourism certification/designation system. The results from the investigation indicate that Europe, since the late 1990s to early 2000, has actively introduced a system that establishes and operates a dedicated institution, and European members have created a cooperation framework to formulate international partnerships and develop standardized assessment benchmarks to adhere to the goals of the system, the period for certification was designated from one year to five years, and renewals were granted based on periodic monitoring and reassessment. In Korea, from early 2000, the Ministry of Culture, Sorts and Tourism and other organizations have certified product quality and assessed travel products and national park tour programs. The certification period was established to be set between one and three years, and the vast majority were not reassessed. Upon investigating the results for awareness of national eco-tourism certification/designation system, a high number of respondents agreed with the need to establish a eco-tourism certification/designation system (90% of respondents), and the respondents cited eco-tourism quality assurance, conservation of value, means to maintain established institutions, and environmental education and information as reasons for needing a certification/designation system. In Korea, a certification/designation system for the eco-tourism industry is presently in operation, but the system regulates target institutions based on their characteristics. Therefore, this study proposes its suggestions via various categories, including designated institutions, designated purpose, designated subjects, designated organization, laws, regulations, and incentives.

Generation Y in the Global Market: A Comparison of South Korean and American Female Decision Making Styles

  • Jackson, Vanessa P.;Lee, Min-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.34 no.6
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    • pp.902-912
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    • 2010
  • This study compares and contrasts the consumer decision-making styles (CDMS) of South Korean and American Generation Y females. A total of 117 American female and 206 Korean female consumers completed self-report survey questionnaires to assess their consumer decision making styles. Exploratory principal components factor analysis using varimax rotation was used to categorize the items into an underlying set of American and Korean decision-making characteristics. Two-tailed independent t-tests were conducted to examine the differences between the two groups when items appeared to have common factors. Factor analysis identified five common factors between the two samples (i.e., enjoyment, shopping aversion, price consciousness, brand consciousness, and quality consciousness). The t-test results report significant differences in the items reported in each factor between American and Korean females. Some of the factors are more indicative of American female Generation Y consumers than Korean female Generation Y consumers. For example, the American female sample seemed to enjoy shopping and prefer brand names more than the female Korean sample. Koreans females seem to have a higher aversion to shopping than Americans; in addition, Koreans females seem to be more accepting of discount and outlet stores, will wait until the price is low before buying a product, and prefer sales when shopping. Based on the findings, the instrument identified varying CDMS between the two samples used. Previous studies using the Sproles and Kendall (1986) instrument experienced the same issue (Bakewell & Mitchell, 2004, 2006; Bauer et al., 2006; Durvasula et al., 1996; Fan & Xiao, 1998; Hanzaee & Aghasibeig, 2008; Mitchell & Walsh, 2004; Siu et al., 2001; Walsh et al., 2001). The results support the idea that no single instrument can be used to examine CDMS in different cultures. This suggests that each country has a CDMS with internal characteristics. Limitations and research for future studies are also discusse.

Microbial Community Structure of Korean Cabbage Kimchi and Ingredients with Denaturing Gradient Gel Electrophoresis

  • Hong, Sung Wook;Choi, Yun-Jeong;Lee, Hae-Won;Yang, Ji-Hee;Lee, Mi-Ai
    • Journal of Microbiology and Biotechnology
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    • v.26 no.6
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    • pp.1057-1062
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    • 2016
  • Kimchi is a traditional Korean fermented vegetable food, the production of which involves brining of Korean cabbage, blending with various other ingredients (red pepper powder, garlic, ginger, salt-pickled seafood, etc.), and fermentation. Recently, kimchi has also become popular in the Western world because of its unique taste and beneficial properties such as antioxidant and antimutagenic activities, which are derived from the various raw materials and secondary metabolites of the fermentative microorganisms used during production. Despite these useful activities, analysis of the microbial community present in kimchi has received relatively little attention. The objective of this study was to evaluate the bacterial community structure from the raw materials, additives, and final kimchi product using the culture-independent method. Specifically, polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) was used to analyze the 16S rRNA partial sequences of the microflora. One primer set for bacteria, 341FGC-518R, reliably produced amplicons from kimchi and its raw materials, and these bands were clearly separated on a 35-65% denaturing gradient gel. Overall, 117 16S rRNA fragments were identified by PCR-DGGE analysis. Pediococcus pentosaceus, Leuconostoc citreum, Leuconostoc gelidum, and Leuconostoc mesenteroides were the dominant bacteria in kimchi. The other strains identified were Tetragenococcus, Pseudomonas, Weissella, and uncultured bacterium. Comprehensive analysis of these microorganisms could provide a more detailed understanding of the biologically active components of kimchi and help improve its quality. PCR-DGGE analysis can be successfully applied to a fermented food to detect unculturable or other species.

A Web-based CBR System for e-Mail Response

  • Yoon, Young-Suk;Lee, Jae-Kwang;Han, Chang-Hee
    • Proceedings of the KAIS Fall Conference
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    • 2003.11a
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    • pp.185-190
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    • 2003
  • Due to the rapid growth of Internet, means of communication with customers in a traditional customer support environment such as telephone calls are being replaced by mainly e-mail in a Web-based customer support system. Although such a Web-based support is efficient and promises potential benefits for firms, including reduced transaction costs, reduced time, and high quality of support, there are some difficulties associated with responding to many types of customer’s inbound e-mails appropriately .As many types of e-mail are received, considerable attention is being paid to methods for increasing the efficiency of managing and responding e-mails. This research proposes an intelligent system for managing customer’s inbound e-mails in organizations by applying case based reasoning technique for responding to various customers' inbound e-mails more effectively. In this approach, a case is represented as a frame-typed data structure corresponding to an inbound e-mail, keywords, and its reply e-mail. In the retrieval procedure, keywords and affinity set is developed to index a case, and then the case is represented as a vector, a case vector. Also, cosines value is calculated to measure the similarity between a new inbound e-mail and the cases in the case base. In the adaptation procedure, we provide several adaptation strategies to adapt and modify the retrieved case. The strategies guide to make an outbound e-mail using product databases, databases for customer support, etc. Additionally, the Web-based system architecture is proposed to implement our methodology. The proposed methodology and system will be helpful for developing more efficient Web-based customer support.

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