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A Study on the Ergonomic features and Their Improvements in Pen Design (필기구 디자인의 인간공학적 제요소와 개선에 관한 연구)

  • 이재환
    • Archives of design research
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    • v.13 no.3
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    • pp.253-260
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    • 2000
  • Writing instruments or pens have many features not commonly found in other products in terms of their structure and characteristics of use. That is, different pens are usually composed of almost identical parts and/or structure. The fact they work always grabbed in hands considered, the ergonomic design of pens is essential. Reports indicate consumers evaluate pens in writing comfort above all other factors when they select pens. Among various factors related to writing comfort, it shouldspecifically be the ergonomic improvements that design can effectively contribute to. Studies on the pen-grabbing comfort or on approaches based on the understanding of human-work relationships generally lack when compared with fashion-conscious aesthetic approaches to pen design. This paper, therefore, aims to reestablish the ergonomic design criteria including the necessities of specifications required to provide indispensable data for the pen design processes. Consequently, it should produce basic set of information for systematic approach to pen design and development, which is commonly called'concurrent engineering'. Also a cost-effective solution for product diversification strategy could be attributed to a modular system database based on the result of this attempt.

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Development of PCR-Based Sequence Characterized DNA Markers for the Identification and Detection, Genetic Diversity of Didymella bryoniae with Random Amplified polymorphic DNA(RAPD)

  • Kyo, Seo-Il;Shim, Chang-Ki;Kim, Dong-Kil;Baep, Dong-Won;Lee, Seon-Chul;Kim, Hee-Kyu
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.130-130
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    • 2003
  • Gummy stem blight pathogen is very difficult not only to monitor the inoculum levels prior to host infection, and also it is destructive and hard to control in field condition. We have applied RAPD technique to elucidate the genetic diversity of the genomic DNA of Didymella bryoniae and also to generate specific diagnostic DNA probe useful for identification and detection. The 40 primers produced clear bands consistently from the genomic DNA of twenty isolates of Didymella bryoniae, and two hundred seventy-three amplified fragments were produced with 40 primers. The combined data from 273 bands was analyzed by a cluster analysis using UPGMA method with an arithmetic average program of NTSYS-PC (Version 1.80) to generate a dendrogram. At the distance level of 0.7, two major RAPD groups were differentiated among 20 strains. RAPD group (RG) I included 8 isolates from watermelon except one isolate from melon. RAPD group (RG) IV included 12 isolates from squash, cucumber, watermelon and melon.. In amplification experiment with SCAR specific primer RG1F-RG1R resulted in a single band of 650bp fragment only for 8 isolates out of 20 isolates that should be designated as RAPD Group 1. However, same set of experiment done with RGIIF-RGIIR did not result in any amplified product.. Our attempts to detect intraspecific diversity of ITS region of rDNA by amplifying ITS region and 17s rDNA region for 20 isolates and restriction digestion of amplified fragment with 12 enzymes did not reveal polymorphic band. In order to develop RAPD markers for RGIV specific primer, a candidate PCR fragment( ≒1.4kb) was purified and Southern hybridized to the amplified fragment RGIV isolates. This promising candidate probe recognized only RGIV isolates

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A Study on the Strategies for Expanding Exports of Indonesia utilizing E-commerce Platform (전자상거래 플랫폼을 활용한 인도네시아 수출확대방안에 관한 연구)

  • Choi, Jang Woo;Park, Jae Han
    • International Commerce and Information Review
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    • v.19 no.1
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    • pp.99-126
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    • 2017
  • The Indonesian e-commerce market has grown significantly due to sustained economic growth, middle class growth, rapid increase in Internet and SNS users, and increase in accessibility of mobile broadband services. In particular, consumers' online shopping through mobile and SNS has been increasing rapidly based on the expansion of the popularity of smart phone devices. This research suggested the strategies for expanding exports of Indonesia through e-commerce platform to the Korean firms, with deep analysis of the current status and features, problems, cases, and implications etc. of Indonesia's e-commerce market. As an export expansion strategy utilizing Indonesia's e-commerce platform, this study showed the Korean firms have to build a local online distribution network, establish a logistics & delivery and payment system, acquire Halal certification for Muslim market, carry out the in-depth market research, actively implement Hanryu marketing strategy, develop a creative product, set up market segmentation strategies, and develop SNS mobile marketing.

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Numerical and Experimental Study on the Increase of Removal Efficiency of SO2 in a Laboratory Scale Electrostatic Spray Drying Absorber (실험실 규모 정전기 분무형 반건식 세정기의 SO2 제거효율 향상에 대한 계산 및 실험적 연구)

  • Byun, Young-Cheol;Hwang, Jung-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.22 no.8
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    • pp.1111-1120
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    • 1998
  • Spray Drying Absorber(SDA) system, where the combustion product gas is mixed with atomized limestone-slurry droplets and then the chemical reaction of $SO_2$ with alkaline components of the liquid droplets forms sulfates, has been widely used to eliminate $SO_2$ gas from coal fired power plants and waste incinerators. Liquid atomization is necessary because it can maximize the reaction efficiency by increasing the total surface area and dispersion angle of the alkaline components. First, numerical calculations using FLUENT are carried out to investigate $SO_2$ concentration distribution and thus to calculate $SO_2$ removal efficiency. So to attain the optimized spray conditions, then an electrostatic spraying system is set up and spray visualization is performed to show the effect of an electric field on overall droplet size. Next, the effect of an electric field on the concentrations of $SO_2$ is experimentally examined. Field strength is varied from -10 kV to 10 kV and configurations of conduction charging and induction charging are utilized. Consequently, the electrostatic removal efficiency of 501 increases about 30% with the applied voltage of ${\pm}10kV$ but is independent of polarity of the applied voltage. It Is also found that the conduction charging configuration results in higher efficiency of $SO_2$ removal that the induction charging configuration. Finally, the effect of slurry temperature on $SO_2$ removal is studied. The temperature influences on the electrostatic removal efficiency of $SO_2$.

Sizing System for Medical Compression Stockings -Focus on Imported Medical Compression Stockings in the Korean Market- (의료용 압박스타킹의 사이즈 체계에 관한 연구 -한국 시장에서의 수입 의료용 압박스타킹을 중심으로-)

  • Do, Wol-Hee;Kim, Nam-Soon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.8
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    • pp.860-874
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    • 2012
  • This study provides size information on current imported medical compression stockings in Korea. A total 20 brands from 6 countries imported and sold in the Korean on-off line markets were selected for this study and the sizing system of medical compression stockings was researched. The results of this study were as follows: there were size differences among different USA brands according to product type or compression class of medical compression stockings. To establish the sizing system for medical stockings of the German brands, the basic body measurements standard was set as cA, cY, cB, cB, cC, cD, cE, cF, cG, cH, cT, lD, lG, and lT. Italian brands developed the sizing system for medical compression stockings by compression class. In the Swiss brands, size types were sub-divided as 'Normal', 'Plus', 'Short', and 'Long'. The sizing 1 were confined within very narrow limits. There were differences of the basic body measurements between Taiwan brands. The results of the comparison of the size range of the imported brands with Size Korea (KATS, 2010) by two-way size distribution shows that the sizing systems of the imported brands were unsuitable for Koreans. To enhance the suitability of the sizing system for medical compression stockings, a new sizing system for Korean adult males and females needs to be established.

Expression of Luteinizing Hormone (LH) Subunit Genes in Mouse Testis

  • Kim, Hee Soo;Lee, Sung-Ho
    • Development and Reproduction
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    • v.21 no.3
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    • pp.327-333
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    • 2017
  • Gonadotropins are heterodimers consisting an alpha chain ($Cg{\alpha}$) and a beta chain. Interestingly, presence of complicated $LH-{\beta}$ transcripts in rat testis was accidently found; testicular $LH-{\beta}$ transcripts were confined in seminiferous tubules to spermatids, and the translated products were localized in the elongated spermatids. We hypothesized that mouse testis has potential to produce the tissue specific $LH-{\beta}$ with similar structure to the rat testicular forms. To verify our hypothesis, we examined the adult mouse (ICR) testis using RT-PCR and immunohistochemistry. The PCR revealed the presence of the identical products in the reactions for three LH subunit types. The expected product sizes for mouse $Cg{\alpha}$ and $LH-{\beta}$ known as pituitary type were 224 bp and 503 bp, respectively. The testicular type $LH-{\beta}$ products were produced by a primer set based on the rat sequences, with unexpected size of 800 bp. Sequencing revealed that the proximal and distal parts (2-82 and 661- 773 bp, respectively) were homologous to rat testicular $LH-{\beta}$ cDNA, and middle part (83-660 bp) was a unique mouse-specific region. Both $Cg{\alpha}$ and $LH-{\beta}$ positive signals were in the round and elongated spermatids and mature sperms, and the $LH-{\beta}$ signals were more intense. In conclusion, our study demonstrated that the presence and localization of the LH subunits in mouse testis. Further studies will be needed to understand the precise structure and function of mouse testicular LH.

Comparison of oral care product use, frequency of dental clinic visits, and oral conditions between individuals who brush and do not brush before sleeping using the 5th and 6th Korean National Health and Nutrition Survey (KNHANES) data (잠자기 전 칫솔질 유무에 따른 구강위생보조용품 사용과 최근 치과진료 및 구강상태 비교 : 국민건강영양조사 제5기와 제6기의 자료를 활용하여)

  • Kim, Yu-Rin
    • Journal of Korean society of Dental Hygiene
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    • v.19 no.6
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    • pp.931-939
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    • 2019
  • Objectives: The purpose of this study was to determine the importance of brushing before sleeping by comparing the use of oral care products, frequency of dental clinic visits, and oral conditions between individuals who brush and do not brush their teeth before sleeping using data from the 5th and 6th Korean National Health and Nutrition Survey (KNHANES). Methods: Statistical analysis was performed using SPSS 21.0 on data files obtained according to a complex sampling design, and a significance level of <0.05 was set. General characteristics of the participants and year were analyzed using chi-square analysis. Data on the oral conditions, use of oral care products, and frequency of dental clinic visits were analyzed using logistic regression and linear regression. Results: Individuals who brushed their teeth before sleeping showed greater use of oral care products and more frequent dental clinic visits, oral examinations, preventive treatment, and treatment for simple caries (p<0.05) than individuals who did not. Individuals who did not brush their teeth before sleeping showed higher prevalence of permanent teeth caries and periodontal disease, as well as chewing and speaking problems (p<0.05), than those who bushed before sleeping. Conclusions: Individuals who do not brush before sleeping exhibit poorer oral health and lower use of oral care products and frequency of recent dental treatment than those who brush before sleeping. Therefore, it is necessary to alter the government's active policy and improve education about the importance of brushing before sleeping to improve oral health.

Barriers Causing the Value Gap between Expected and Realized Value in IS Investment: SCM/ERP/CRM (정보시스템 투자 전후 가치 격차 유발 장애요인: 탐색적 사례연구)

  • Cho, Nam-Jae;Park, Ki-Ho
    • Information Systems Review
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    • v.5 no.1
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    • pp.1-18
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    • 2003
  • Many organizations experience that the value they gained from IT (information technology) investment is lower than they expected prior to the actual implementation of a system - the value gap between expected value and realized value from IT. Research on the barriers to the expectation and realization is of high importance both in practice and in IS research. This study analyzed such barriers observed in three companies that have adopted such IT systems as Enterprise Resource Planning (ERP), Supply Chain Management (SCM), and Customer Relationship Management (CRM) systems each. From analyses of the three companies we specifically identified eight types of barriers: barriers related to industry, organization, knowledge, resource, usage, competence, product, and safety. Common barriers among the three cases were classified into six types, e.g. lack of strategic mind-set, improper organizational structure, lack of human resource, etc. We expect that the results help managers in IS investment to minimize the valuation gap and maximize realized values.

Optimization of Passenger Safety Restraint System for USNCAP by Response Surface Methodology (USNCAP에 대응하는 반응표면법을 이용한 조수석 안전구속장치 최적화)

  • Oh, Eun-Kyung;Lee, Ki-Sun;Son, Chang-Kyu;Kim, Dong-Seok;Chae, Soo-Won
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.6
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    • pp.1-8
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    • 2014
  • Safety performance of a new car is evaluated through USNCAP and their results in the star rating are provided to the consumers. It is very important to obtain high score of USNCAP to appeal their performance to consumers. Therefore the car companies have made the effort to improve their car safety performance. These efforts should satisfy the demand not only to get high score but also to pass the FMVSS, NHTSA regulations on safety. Huge numbers of car crash tests have been conducted on these bases by car companies. However physical tests spend too much cost and time, as an alternative way, the simulation on the car crash could be a solution to reduce the cost and time. Therefore the simulations have been widely conducted in car industry and various researches on this have been reported. In this study, restraint system had been optimized to minimize the injury of female passenger. Belted $5^{th}%ile$ female frontal crash test was selected from various test methods of USNCAP for the study. Initial velocity of the test was 56km/h. The combination injury probability of USNCAP was selected as an objective function and the injury limit value, which was defined in FMVSS, was set to an optimization constraint. Many researches that were similar to this study had been conducted, however most of them had limitation that interaction between airbag and safety belt had not been considered. Contrary to these researches, the interaction was considered in this study.

Effect of Induction Temperature on the $P_L$ Promoter Controlled Production of Recombinant Human Interleukin-2 in Escherichia coli

  • Lee, In-Young;Kim, Myung-Kuk;Lee, Sun-Bok
    • Journal of Microbiology and Biotechnology
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    • v.2 no.1
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    • pp.26-34
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    • 1992
  • The effect of induction temperature on fermentation parameters has been investigated extensively using Escherichia coli M5248[pNKM21], a producer of recombinant human interleukin-2 (rhIL-2). In this recombinant microorganism, the gene expression of rhIL-2 is regulated by the cI857 repressor and $P_L$ promoter system. The recombinant fermentation parameters studied in this work include the cell growth, protein synthesis, cell viability, plasmid stability, $\beta$-lactamase activity, and rhIL-2 productivity. Interrelationships of such fermentation parameters have been analyzed through a quantitative assessment of the experimental data set obtained at eight different culture conditions. While the expression of rhIL-2 gene was repressed at culture temperatures below $34^\circ{C}$ with little effect on other fermentation parameters, under the conditions of rhIL-2 production $>(36~44^\circ{C})$ the cell growth, plasmid stability, and $\beta$-lactamase activity were, as induction temperature was increased, more profoundly reduced. Although the rhIL-2 content in the insoluble protein fraction was maximum at $40^\circ{C}$, total rhIL-2 production in the culture volume was found to be highest at the induction temperature of $36^\circ{C}$. This was in contrast to the previously known optimum induction temperature of the P$_{L}$ promoter system $>(40~42^\circ{C})$.Explanations for such a discrepancy have been proposed based on a product formation kinetics, and their implications have been discussed in detail.l.

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