• Title/Summary/Keyword: Service Unit

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Role of Nuclear Factor-κB in female Breast Cancer: A Study in Indian Patients

  • Jana, Debarshi;Das, Soumen;Sarkar, Diptendra Kumar;Mandal, Syamsundar;Maji, Abhiram;Mukhopadhyay, Madhumita
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5511-5515
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    • 2012
  • Introduction: The nuclear factor ${\kappa}B$ (NF-${\kappa}B$) is a super family of transcription factors which plays important roles in development and progression of cancer. The present investigation concerns NF-${\kappa}B$ /p65 activity in human breast cancers with overexpression of ER, PR, HER-2/neu, as well as the significance of p65 expression with regard to menopausal status, stage, grade, tumor size, nodal status, and NPI of invasive ductal carcinomas in Eastern India. Materials and Methods: In this hospital based study 57 breast cancer patients attending a Breast Clinic of a reputed institute of Eastern India were assessed for p65 protein expression in breast tumor tissue samples by Western blotting. ER, PR and HER-2/neu expression was determined by immunohistochemistry. Results: NF-${\kappa}B$/p65 was significantly associated with advanced stage, large tumor size (${\geq}5$ cm), high grade, negative ER, negative PR, and positive HER-2/neu. High NF-${\kappa}B$/p65 expression was more frequent in patients with a high NPI ($NPI{\geq}5.4$, 84.6%) compared with low NPI (<5.4, 44.4%) and this association was statistically significant (p = 0.002). Conclusion: NF-${\kappa}B$/p65 overexpression was associated with advanced stage, large tumor size, high grade, and high NPI which are poor prognostic factors linked to enhanced aggressiveness of the disease. NF-${\kappa}B$/p65 expression implies aggressive biological behavior of breast cancer and this study validates significant association of NF-${\kappa}B$ /p65 overexpression with negative estrogen and progesterone receptor status and overexpression of HER-2/neu oncoprotein. In our good clinical practice, patients with NF-${\kappa}B$ positive tumors need to be treated aggressively.

A Study on IEC61850-9-2 Distributed Sampled Measured Values Applications for Merging Unit at Process Level (프로세스 레벨의 병합 단위장치를 위한 IEC61850-9-2 샘플링 값 서비스 구현에 관한 연구)

  • Kim, Gwan-Su;Lee, Hong-Hee;Kim, Byung-Jin
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.7
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    • pp.1177-1182
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    • 2007
  • Recently, IEC61850 supports the standardized communication technique in both station bus and process bus, and presents the substation automation model. In this paper, we propose the required techniques to develop the Merging Unit (MU), which is one of the important data acquisition equipment in substation automation, under IEC61850 communication protocol. Especially, we also propose the precision time synchronization technique using GPS(Global Positioning System) for the MU. IEC61850-9-2 SV (Sampled Value) service is applied to the MU which is designed using microprocessor. In order to evaluate the performance of the proposed MU, the playback program, which can reconstruct the transmitted sampled value data on the basis of time information, is developed and the performance of the IEC61850 SV service for MU is verified experimentally.

The Study of Distributed Disturbance Recording System (분산형 사고파형저장 시스템에 대한 연구)

  • Park, Jong-Chan;Lee, Se-In
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.57 no.1
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    • pp.30-35
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    • 2008
  • In this paper, the application of power Quality monitoring based on Sampled Value(SV) which is introduced in the IEC61850 International Standard for substation communication are discussed. Firstly, while Merging Unit(MU) is designed as a process level device transmitting sensor data, the practical problems such as time delay compensation and optical fiber communication are encountered. Secondly, the Sampled Value message which is proper to a power quality monitoring system is presented. Because the power quality monitoring system requests less time-critical service compared to protection and control applications, the Sampled Value service message structure is introduced to improve efficiency. Lastly, the power quality monitoring server having various power quality analysis functions is suggested to verify the performance of Merging Unit With the diverse experiments, it is proved that the process bus distributed solution is flexible and economic for the power quality monitoring.

IEC61850 Process Bus Based Distributed Power Quality Monitoring (IEC61850 프로세서 버스 기반 분산형 전력품질감시)

  • Park, Jong-Chan;Kim, Byung-Jin
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.56 no.1
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    • pp.13-18
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    • 2007
  • In this paper, authors deal with an application of power quality monitoring using the Sampled Value which is described in the IEC61850 International Standard for substation communication. Firstly, while Merging Unit is designed as a process level device transmitting sensor data, the practical problems such as time delay compensation and optical fiber communication are issued. Secondly, the Sampled Value message which is proper to a power quality monitoring system is presented. Because the power quality monitoring system requests non time critical service comparing to protection and control applications, the Sampled Value service message structure is introduced to improve efficiency. At last, the power quality monitoring server having various power quality analysis functions is suggested to verify the performance of Merging Unit. With the diverse experiments, it is proved that the process bus distributed solution is flexible and economic for the power quality monitoring.

Antifungal Activity of a Synthetic Cationic Peptide against the Plant Pathogens Colletotrichum graminicola and Three Fusarium Species

  • Johnson, Eric T.;Evans, Kervin O.;Dowd, Patrick F.
    • The Plant Pathology Journal
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    • v.31 no.3
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    • pp.316-321
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    • 2015
  • A small cationic peptide (JH8944) was tested for activity against a number of pathogens of agricultural crops. JH8944 inhibited conidium growth in most of the tested plant pathogens with a dose of $50{\mu}g/ml$, although one isolate of Fusarium oxysporum was inhibited at $5{\mu}g/ml$ of JH8944. Most conidia of Fusarium graminearum were killed within 6 hours of treatment with $50{\mu}g/ml$ of JH8944. Germinating F. graminearum conidia required $238{\mu}g/ml$ of JH8944 for 90% growth inhibition. The peptide did not cause any damage to tissues surrounding maize leaf punctures when tested at a higher concentration of $250{\mu}g/ml$ even after 3 days. Liposomes consisting of phosphatidylglycerol were susceptible to leakage after treatment with 25 and $50{\mu}g/ml$ of JH8944. These experiments suggest this peptide destroys fungal membrane integrity and could be utilized for control of crop fungal pathogens.

A Case Study on the Perception of Interaction Quality in Military Logistics Support Service: Focused on Maintenance Function (군수지원 서비스에서 상호작용품질 인식에 대한 사례연구 : 정비기능을 중심으로)

  • Cho, Chong Mok;Kim, Jong Weon;Hong, Suk Ki
    • Journal of Korea Society of Industrial Information Systems
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    • v.22 no.3
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    • pp.63-76
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    • 2017
  • While the Military Logistics System and its Outcome Quality have been Emphasized, User Unit's needs on Interaction Quality Begin to Appears as a New Subject in Logistics Field. Interaction Quality of Supply, Maintenance and Foods Among Logistics Functions Influenced much more to User Unit's Satisfaction. Especially Maintenance on Satisfaction was Prominent. Analyses of the Survey and Interview with Field Employees Supported the Results, and the Characteristics of Maintenance Function also Accord with those. Moreover, the Service Maintenance Employees, who Showed Higher Job Satisfaction Among Three Functions, led to Higher Satisfaction of User Units.

Wolsong 3&4 Steam Generator Tube Inspection (월성 3,4호기 증기발생기 전열관 검사)

  • Jang, Kyoung-Sik;Kwon, Dong-Ki;Choi, Jin-Hyuk;Son, Tai-Bong
    • Proceedings of the KSME Conference
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    • 2001.11b
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    • pp.859-866
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    • 2001
  • During the Pre-service Inspection for Wolsong Unit 3&4 in 1997/1998 respectively, 17 Distorted Roll Transition indications(over expanded beyond tubesheet secondary face) were identified at the Unit 4 (S/G B, D). Six(6) tubes out of these tubes were plugged in 1998. However the first Periodic Inspection identified additional 110 indications in 1999 and 2000. The additionally identified 110 indication call, not reported at the Pre-service Inspection, are; 2 Not-Finally-Expanded-Tubes and 108 Distorted Roll Transition tubes. Design limit of each Steam Generator tube Plugging is 6.4%. Plugging was performed by the Steam Generator manufacturer under the warranty. When Distorted Roll Transition indications were first identified on the Unit 4 in 1998 the degree of Over-expansion was measured using an inner dial-gage to make the disposition of Nonconformance report. 2 Not-Finally-Expanded-Tubes were plugged and 10 tubes out of 108 Distorted Roll Transition Tubes were also plugged as a preventive measure.

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Research for the Chemical Emergency Oxygen Supply and Lighting System for Aircraft Passengers (항공기 승객용 화학적 비상산소 공급 및 조명시스템에 대한 연구)

  • Kim, Young-In
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.30 no.2
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    • pp.55-60
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    • 2022
  • A PSU (passenger service unit) is mounted on passenger seats in a cabin on an aircraft and consists of a crew call lamp, a reading lights, an information display lamp, an emergency oxygen generator, and an emergency oxygen mask. It is a safety device for providing convenience to passengers and providing oxygen to passengers in an emergency. This paper is a study on emergency oxygen supply systems and light systems of aircraft PSUs and a control device was developed to operate the system by analyzing the B767-300 aircraft's PSU circuit diagram. And the temperature generated by the B777-200ER aircraft's emergency oxygen generator was also measured by operating it directly. Through this, precautions for explaining the operation of an oxygen mask in an emergency were described and improvements were presented. Data acquired in these research processes can be used in the future to develop aircraft PSU (passenger service unit) and emergency oxygen generators.

Analysis on the Unit-Plans of Shinonome Canal Court Multi-dwellings Project in Japan (일본 공동주택 시노노메 캐널코트의 단위세대 주거평면 분석)

  • Suh, Kuee-Sook
    • Journal of the Korean housing association
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    • v.19 no.2
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    • pp.43-54
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    • 2008
  • The aim of the research is to find out the direction of unit-plans in multi-dwellings for the future society. Shinonome Canal Court where residents actually live now are the objects in this study, and the residential floor plan of unit-plans were analyzed to find out the typical types. The analysis was focused on the unit-plans of 5 blocks of Shinonome Canal Court. Space Syntax Theory was used as the analysis method. As the first stage of the analysis, justified graphs were made to find out the characters of unit-plans through the classification of the graphs. Contents of the analysis are as follows: Relationship between classified justified graphs and dimension according to node number. Relationship between classified justified graph patterns and unit-plans. Characters of unit-plans in each blocks. Shinonome Canal Court consists of mainly small scale unit-plans and 30unit-plans are classified. 1LDK, 2LDK, 1LDK+S, 1LDK+f are typical unit-plans which are mainly supplied in the complex. It is noted that the results of the analysis by node, justified graph pattern and dimension are the same. It also presents diverse unit-plans which shows a change in nLDK pattern or add f (foyer), AN (annex), S (service room), Fs (free space) to basic nLDK type. In summary, it demonstrates the possibility of creating new residental floor plans in multi-dwellings.