• 한국응용과학기술학회지
• /
• 제27권1호
• /
• pp.14-19
• /
• 2010

In this study, the anti-oxidative effects and components of sprout serum were investigated. In the buds, high levels of zinc, iron and manganese were analyzed in addition to copper, magnesium, and potassium. The free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity of sprout serum was evaluated with $IC_{50}$. $IC_{50}$ of sprout serum was $58.0\;mgmL^{-1}$, and that of vitamin C was $3.7\;mgmL^{-1}$. In the test of superoxide scavenging activity of sprout serum, the activity was dependent on the concentration of serum. In this case, the $IC_{50}$ was 2.0 wt%. Cell viability was detected by using the MTT method. Cultured human fibroblast was treated with 15 mM $H_2O_2$ and cell viability was 70% in case of control. However, the effect of treating 0.5% of sprout serum was similar to that of 0.0001% of vitamin C.

• Journal of Periodontal and Implant Science
• /
• 제1권1호
• /
• pp.1-1
• /
• 1971

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제31권1호
• /
• pp.41-45
• /
• 2020

Objective: The objective of this study was to assess serum, hair, and urinary magnesium (Mg) levels in children with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and both ASD and ADHD to reveal potential interactive effects. Methods: A total of 148 boys aged 4-9 years old were enrolled in this study, including 44 children with ADHD, 40 pediatric patients with ASD, 32 patients with both ADHD and ASD, as well as 32 healthy neurotypical children. Hair, serum, and urinary Mg levels were assessed using inductively-coupled plasma mass spectrometry (ICP-MS). Laboratory quality control was performed using certified reference materials of human hair, plasma, and urine. Results: No significant group difference in serum Mg levels was observed. Mg content in hair was found to be reduced in children with ADHD and ADHD+ASD compared to that in healthy controls by 11% and 15%, respectively. Urinary Mg levels in children with ADHD+ASD exceeded the control, ADHD, and ASD values by 51, 76, and 65%, respectively. Factorial analysis revealed significant contribution of ADHD to hair and urinary Mg levels. Multiple regression analysis demonstrated that hair and urinary Mg levels were considered as significant predictors of neurodevelopmental disorder complexity. Conclusion: We propose that impaired Mg status may provide a link between ADHD and ASD.

• Asian-Australasian Journal of Animal Sciences
• /
• 제23권6호
• /
• pp.708-718
• /
• 2010

The objective of the current study was to determine seasonal changes in glucose, cholesterol, non-esterified fatty acids (NEFA), serum inorganic phosphorous (SIP), calcium, magnesium and iron concentrations in Nguni and crossbred cattle on the sweet and sour rangelands of the Eastern Cape Province of South Africa. Body weights, body condition scores (BCS) and serum concentrations of energy-related metabolites and mineral profiles were determined in late cool-dry, hot-dry, hot-wet, post-rainy and early cool-dry seasons in 100 cattle raised on communal rangelands from August 2007 to May 2008. Nguni cattle had lower (p<0.05) and higher (p<0.05) serum concentrations of glucose in the hot-wet and post-rainy seasons, respectively, compared to crossbreds in the same seasons. Serum cholesterol and NEFA concentrations in Nguni were lower (p<0.05) than in the crossbreds. Nguni and crossbred cattle had higher (p<0.05) serum NEFA concentrations on the sweet rangeland during the late cool-dry season than on sour rangeland. Nguni cattle had higher (p<0.05) SIP concentration in the hot-wet season than the crossbreds. Generally, both breeds had lowest SIP concentration during the hot-wet season on the sour rangeland. The lowest magnesium and highest iron concentrations were observed in the hot-wet and post-rainy seasons, respectively, compared to other seasons. Cattle on the sour rangeland had lower (p<0.05) iron concentrations than those on the sweet rangeland. It was concluded that Nguni cattle had lower cholesterol and NEFA, and higher SIP concentrations in the hot-wet season than crossbreds and energy deficits mostly occurred during the late cool-dry season on the sweet rangeland.

• 대한한방부인과학회지
• /
• 제19권2호
• /
• pp.107-126
• /
• 2006

Purpose : This study was peformed to evaluate the effect of Kamijoaguiem(JGE) on the bone mass and its related factors. Methods : We used ovariectomized rat as an estrogen-deficient animal model. The model rats of osteoporosis showed a significant decrease in bone density, bone ash density, calcium content of femur bone. At the 7th day after operating ovariectomy, rats were administered with JGE per orally, and continued for 10 weeks. And osteoporosis related parameters were determined to investigate the effect of JGE. Results : Bone density, bone ash density, bone calcium, magnesium and phosphorus was decreased in osteoporotic rats. JGE improved the decreased bone density, bone ash density and the decreased bone magnesium, but JGE didn't improve the decreased bone calcium and phosphorus in osteoporotic rats. Osteocalcin in serum and hydroxy-proline excretion in urine were increased in osteoporotic rats. Their levels were decreased when JGE was administered. ALP activity in serum was increased in osteoporotic rats. JGE didn't induce any significant changes. JGE showed significant increase in serum calcium level, total protein level, albumin level, BUN level, serum LDH activity. JGE didn't show significant increase in serum T-cholesterol density, triglyceride density, HDL-cholesterol density. JGE didn't show significant increase in RBC number, hemoglobin level, platelet number, hematocrit level. JGE showed inhibitory effect on the degradation of bone-matrix in osteoporotic rats, in histological examination to Hematoxylin-eosin stain. Conclusion : JGE might improve bone density due to inhibition of bone resolution in osteoporotic rats. It suggest that JGE may be useful prescription in osteoporosis.

• 대한수의학회지
• /
• 제28권1호
• /
• pp.165-168
• /
• 1988

Some hematological and biochemical indices were assayed in Korean native cattle naturally harbouring Fasciola hepatica infection and compared with uninfected controls. Affected animals revealed reduction in total erythrocyte count and hemoglobin content, and increase in total leukocyte count. Infected cattle had significantly lower levels of serum total protein, serum albumin and magnesium. Significantly higher values were obtained for the serum enzymes aspartate aminotransferase and alanine aminotransferase.

• 대한지역사회영양학회지
• /
• 제2권4호
• /
• pp.477-485
• /
• 1997

This study was conducted to determine the effect of large amounts of whole cow's milk intake on serum levels of minerals and lipids. Subjects were normal infants who were brought to the pediatric hospital for vaccination at the age of 7-26 months after birth, living in Eumsung-Choongbuk area. The serum concentrations of the imnerals(calcium, phosphorus, magnesium, iron, zinc and copper), lipids and fatty acids composition were analyzed in 38 infants which consumed large amount of whole cow's milk(over 700ml/day). The results obtained are summarized as follows : 1) The mean levels of calcium, phosphorus and magnesium in the serum of the total subjects were 7.56$\pm$0.51mg/dl, 11.12$\pm$0.72mg/dl and 1.62$\pm$0.13mg/dl respectively. The serum concentrations of iron, zinc and copper in total subjects averaged 72.42$\pm$1.62$\mu\textrm{g}$/dl, 76.29$\pm$3. 62$\mu\textrm{g}$/dl and 86.44$\pm$2.98$\mu\textrm{g}$/dl respectively. 2) The mean serum concentrations of triglyceride, total cholesterol, HDL and LDL in the total number of subjects were 96.84$\pm$9.22mg/dl, 133.45$\pm$6.30mg/dl, 32.79$\pm$1.77mg/dl and 81.29$\pm$4.81mg/dl respectively. 3) The average percentages of SFA, MUFA and PUFA inth total serum fatty acids were 38.98$\pm$2.42$\%$, 25.82$\pm$0.98$\%$ and 37.30$\pm$1.09$\%$ respectively and the mean$w6/w3$fatty acids ratio was 13.48. In general, the levels of serum minerals and $\omega$3 fatty acid composition in the subjects of this study, who were whole cow's milk fed infants were lower than those reported in breast milk or formula fed infants. Therefore, the intake of large amount of whole cow's milk in the weani ng period should be controlled and adequate for the infant's nutritional status. (Korean J Community 2(4) : 477-485, 1997)

• Asian-Australasian Journal of Animal Sciences
• /
• 제12권2호
• /
• pp.189-191
• /
• 1999

Mineral profile of serum and cerebrospinal fluid (CSF) of 15 Himalayan Yak (adult female, n=8; adult male n=4 and young male,n=3) was studied in their natural habitat at an altitude of 3300 meters above mean sea level at Sangla in north western Himalayas. The macro and micro minerals estimated in serum and CSF were; Sodium, Potassium, Calcium and Magnesium and Zinc, Copper and Iron respectively. The values recorded among different Yak groups did not significantly differ from each other except serum iron and haemoglobin which were significantly higher (p<0.05 ) in young male Yaks compared to the adult male and female Yaks. An observation of great significance was considerably higher potassium and lower sodium level in Yaks compared to other bovine species of plains. The serum potassium values in some adult female Yaks were recorded as high as 10.4 mEq/l and the values varied between 6.6 to 9.8 mEq/l in young male Yaks. The serum Sodium values and Na:K ratios in Yak serum ranged between 117.5 to 122.6 mEq/l and 13.7 to 15.3 respectively. The possible relationship of high serum Potassium value with hypoxic conditions and hostile mountain environment has been discussed.

• Journal of Community Nutrition
• /
• 제1권2호
• /
• pp.88-97
• /
• 1999

The purpose of this study was to investigate the nutritional status of serum minerals, ceruloplasmin, and ferroxidase activity in female adolescent students according to their smoking status. The subjects were 87 non-smokers and 88 smokers, who were female high school students. The smokers were divided into tow groups by smoking status, 35 light smokers(pack-year<1) and 53 smokers(pack-year$\geq$1). The serum concentrations of 6 minerals were determined by ICP emission spectroanalyzer. The serum concentration of ceruloplasmin and ceruloplasmin ferroxidase activity were determined. All data were statistically analyzed by SAS PC package program. The serum minerals concentrations of all subjects were in a normal range. There were significantly differences in the concentrations of serum copper, zinc, magnesium, and phosphorus by smoking status while there were no significant differences in the concentrations of serum iron and manganese by smoking status. Furthermore there were no significant differences in the ceruloplasmin concentration and ferroxidase activity by smoking status. In conclusion, smoking status altered the serum levels of some minerals in healthy young women. The minerals levels in light smokers with relatively short pack-year(pack-year<1) were altered compared to those in non-smokers or smokers. This finding seemed to be consistent with the results of previously published data related to antioxidant vitamin and lipid peroxide levels. However further research is needed to clarify these findings in female adolescent smokers.

• 한국임상수의학회지
• /
• 제35권6호
• /
• pp.258-265
• /
• 2018

We aimed to identify the relationships between puerperal metritis (PM) and serum metabolites, uterine health, milk yield, and reproductive performance in dairy cows. Blood samples from 150 Holstein dairy cows were collected just after calving, and at 1, 2, and 4 weeks postpartum to measure serum concentrations of ${\beta}$-hydroxybutyrate (BHBA), urea nitrogen, total cholesterol (TCH), albumin, aspartate aminotransferase (AST), calcium, and magnesium. PM was diagnosed by the presence of fever (${\geq}39.5^{\circ}C$) and a watery, fetid uterine discharge during the first 14 days after calving. Cows were divided into two groups on the basis of the presence or absence of the disease: a control group (n = 83) and a PM group (n = 67). The cows diagnosed with PM were subcutaneously administered with 2.2 mg/kg ceftiofur for 3-5 days. The serum concentrations of BHBA tended to be higher (P = 0.06) and AST was higher (P < 0.05) in the PM group than in the control group 1 week after calving, whereas serum concentrations of urea nitrogen, TCH, albumin, calcium, and magnesium were lower (P < 0.05-0.0001) after calving in the PM group than in the control group. The probability of clinical endometritis was higher (odds ratio = 5.40, P < 0.001) in the PM group than in the control group. Moreover, the proportion of neutrophils in the uterus was also higher in the PM group than in the control group 4, 6, and 8 weeks after calving (P < 0.001). The mean milk yield 1 and 2 months after calving was lower (P = 0.05) in the PM group than in the control group. The hazard of pregnancy by 180 days after calving tended to be lower (hazard ratio = 0.60, P = 0.07) in the PM group than in the control group, which led to an extended mean interval between calving and pregnancy (19 days) in the PM group (P < 0.01). In conclusion, PM is associated with higher postpartum concentrations of BHBA and AST, and lower concentrations of urea nitrogen, TCH, albumin, calcium, and magnesium. Moreover, PM is associated with subsequent poor uterine health, lower milk yield, and poorer reproductive performance in dairy cows.