• Journal of Digital Contents Society
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• v.14 no.2
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• pp.215-222
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• 2013

NAND flash memory-based Solid State Drives (SSD) have lots of merits compared to traditional hard disk drives (HDD). However, random write in SSD is still far slower than sequential read/write and random read. There are two independent approaches to resolve this problem: 1) using part of the flash memory blocks as log blocks, and 2) using internal write buffer (DRAM or Non-Volatile RAM) in SSD. While log blocks are managed by the Flash Translation Layer (FTL), write buffer management has been treated separately from FTL. Write buffer management schemes did not use the exact status of log blocks and log block management schemes in FTL did not consider the behavior of write buffer management scheme. In this paper, we first show that log blocks and write buffer have a tight relationship to each other, which necessitates integrated management of both of them. Since log blocks also can be viewed as another type of write buffer, we can manage both of them as an integrated write buffer. Then we provide three design criteria for the integrated write buffer management scheme which can be very useful to SSD firmware designers.

• Tuberculosis and Respiratory Diseases
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• v.67 no.5
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• pp.402-408
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• 2009

Background: Pre-B-cell colony enhancing factor (PBEF) has been suggested as a novel biomarker in sepsis and acute lung injury. We measured the PBEF in bronchoalveolar lavage (BAL) fluid of acute critically ill patients with lung infiltrates in order to evaluate the clinical utility of measuring PBEF in BAL fluid. Methods: BAL fluid was collected by bronchoscope from 185 adult patients with lung infiltrates. An enzyme-linked immunosorbent assay was then performed on the collected fluids to measure the PBEF. Results: Mean patient age was 59.9 ${\pm}$14.5 years and 63.8% of patients were males. The mean concentration of PBEF in BAL fluid was 17.5 ${\pm}$88.3 ng/mL, and patients with more than 9 ng/mL of PBEF concentration (n=26, 14.1%) had higher Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores on the BAL exam day. However, there were no significant differences in clinical characteristics between survivors and non-survivors. In patients with leukocytosis (n=93) seen on the BAL exam day, the linear regression analysis revealed a significant, positive relationship between PBEF and APACHE II ($r^2$=0.06), SOFA score ($r^2$=0.08), Clinical Pulmonary Infection Score ($r^2$=0.05), and plateau pressure in patients on ventilators ($r^2$=0.07) (p<0.05, respectively). In addition, multivariate regression analysis with PBEF as a dependent variable showed that the plateau pressure ($r^2$=0.177, p<0.05) was correlated positively with PBEF. Conclusion: The PBEF level in the BAL fluid may be a useful, new biomarker for predicting the severity of illness and ventilator-induced lung injury in critically ill patients with lung infiltates and leukocytosis.

• Journal of KIBIM
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• v.6 no.3
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• pp.34-41
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• 2016

The previous studies argue that using the semantic properties of BIM objects is efficient for simulating the behaviors of autonomous, computer agents, called virtual-users, but such assumption is not proven via evidence-based research approaches. Hence, this present study aims to investigate the empirical effects of a human behavior simulation model equipped the semantics of spaces on the architecture-major students' operation and understanding of the simulation system, compared to a typical path-finding model. To achieve the aim, this study analyzed the survey and interview data, collected in the authentic design projects. The analysis indicates that (1) using a simulation model equipped the semantics of spaces helps the students' operation of the simulation, and (2) it also aids understanding the relationship between the variables of spaces and virtual-users (${\alpha}=0.74$). In addition, the qualitative data inform that the advantages of the simulation model that computes the semantics of spaces stem in the automatic behavioral changes of massive numbers of virtual-users, and efficient detection and activation on the what-if situations. The analysis also reveals that the simulation model has shortcomings in orchestrating the complex data structure between the semantics properties of spaces and virtual-users under multi-sequential scenarios. The results of this study contribute to develop a future design system combining BIM with human behavior simulation.

• The Korean Journal of Pharmacology
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• v.20 no.2
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• pp.1-6
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• 1984

It has been generally recognized that the secretion of aldosterone is mainly regulated by angiotensin II in animals and humans, however, potassium and ACTH are also proposed as other humoral factors involved in the aldosterone secretory process. Recently, stress, anesthesia, adrenergic stimulation, low sodium intake or water deprivation stimulate plasma renin activity, while high sodium intake and deoxycorticosteroid have been reported to cause suppression of renin activity in animals. It seems that overall response of aldosterone secretory mechanisms reflects complex interactions both intrarenal and extrarenal components. Furosemide has been widely used to investigate the control of renin secretion by the kidney, and the relationship between diuretics and the disposition of endogenous aldosterone were reported (Oh, 1984). The sequential with 10 min interval samples of plasma were collected following administration of furosemide(1 mg/kg), aspirin(10 mg/kg), respectively. And also similar experiment was performed in the propranolol (10 mg/kg) pretreated rabbits. The results were as follows : 1) The concentration of plasma aldosterone was average of $426.I{\sim}485.5pg/ml$ in normal rabbits. Plasma concentrations of aldosterone rised significantly after injection of furosemide during 50 min, and the rise of plasma aldosterone was blocked by the propranolol pretreatment 2) Significant fall in the plasma level of aldosterone after injection of aspirin was noted. This result indicates that the increased secretion of aldosterone induced by furosemide administration is mediated through ${\beta}-receptors$, and the possible role of prostaglandin is substantiated.

• Journal of KIISE:Databases
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• v.29 no.2
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• pp.119-127
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• 2002

Video server which stores video streams should serve more users with the requested streams rapidly, satisfying their time constraints. However, the number of users supported and the response times for the requested services in video server are in the oppositional relationship with viewpoint of disk throughput. In this paper, we propose new policy that can provide not only rapid responses for the service requests but also increase the number of users supported in the storage system of video server. The policy admits the random movements of disk heads for urgent service requests but maintains the sequential or restricted movements of disk heads and eliminates rewind time of disk heads for less-urgent service requests in storage system of multiple disks environment so that it can not satisfy only the QoS of users but also support more users.

• Journal of Korean Society of Steel Construction
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• v.10 no.1 s.34
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• pp.125-135
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• 1998

This study presents a design method for three-span continuous preflex composite girder bridges (3S-PCB) which imposes prestresses in the negative moment region by lifting or lowering interior supports and the design method is automated by a computer program which incorporates optimal design procedure. The objective function for the design of 3S-PCB minimizes the cost of construction materials and the constraint functions represent the limited dimensions of the design section and the allowable stress for each structural member as given in the specifications. Optimal design procedure used in this study is a modification of existing sequential unconstrained minimization technique (SUMT), a numerical analyses procedure for two-span continuous preflex composite bridges. The optimized design sections determined for each span length are compared with those of simple preflex composite beams (SPCB) and the optimal girder depth is determined by defining the relationship between girder depth and construction material costs.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.1 no.2
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• pp.130-136
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• 2015

We evaluate the influence of MR contrast agent on positron emission tomography (PET) image using phantom, animal and human studies. Phantom consisted of 15 solutions with the mixture of various concentrations of Gd-based MR contrast agent and fixed activity of [$^{18}F$]FDG. Animal study was performed using rabbit and two kinds of MR contrast agents. After injecting contrast agent, CT or MRI scanning was performed at 1, 2, 5, 10, and 20 minutes. PET image was obtained using clinical PET/CT scan, and attenuation correction was performed using the all CT images. The values of HU, PET activity and MRI intensity were obtained from ROIs in each phantom and organ regions. In clinical study, patients (n=20) with breast cancer underwent sequential acquisitions of early [$^{18}F$]FDG PET/CT, MRI and delayed PET/CT. In phantom study, as the concentration increased, the CT attenuation and PET activity also increased. However, there was no relationship between the PET activity and the concentration in the clinical dose range of contrast agent. In animal study, change of PET activity was not significant at all time point of CT scan both MR contrast agents. There was no significant change of HU between early and delayed CT, except for kidney. Early and delayed SUV in tumor and liver showed significant increase and decrease, respectively (P<0.05). Under the condition of most clinical study (< 0.2 mM), MR contrast agent did not influence on PET image quantitation.

• KIPS Transactions on Software and Data Engineering
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• v.3 no.2
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• pp.93-100
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• 2014

3D object recognition using only 2D images is a difficult work because each images are generated different to according to the view direction of cameras. Because SIFT algorithm defines the local features of the projected images, recognition result is particularly limited in case of input images with strong perspective transformation. In this paper, we propose the object recognition method that improves SIFT algorithm by using several sequential images captured from rotating 3D object around a rotation axis. We use the geometric relationship between adjacent images and merge several images into a generated feature space during recognizing object. To clarify effectiveness of the proposed algorithm, we keep constantly the camera position and illumination conditions. This method can recognize the appearance of 3D objects that previous approach can not recognize with usually SIFT algorithm.

• Korean Journal of Soil Science and Fertilizer
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• v.48 no.5
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• pp.391-396
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• 2015

Arsenic (As) contamination of agricultural soils resulting from mining activity has caused major concern due to the potential health risk. Therefore the current study was carried out to investigate the relationship between fractionation of As in soil and rice uptake and to provide a basic information for adequate management of As contaminated agricultural soil. Twenty agricultural soils and rice affected by the abandoned mining sites were collected. Soil chemical properties and As concentrations (total and sequential extracted) in soils were determined and As concentrations in polished rice were analyzed. The average concentration of As in non-specifically adsorbed (F1), specifically adsorbed (F2), amorphous hydrous oxides of Fe and Al (F3), crystalline hydrous oxides of Fe and Al (F4) and residual phase (F5) were 0.08, 1.38, 10.34, 3.26 and $10.98mgkg^{-1}$, respectively. Both soil pH and available phosphorus were positively correlated with the concentrations of As in F1 and F2. These results indicate that increasing the soil pH and available phosphorus can significantly increase the easily mobile fractions of As (F1 and F2). The average concentration of As in polished rice was $0.09mgkg^{-1}$. The concentrations of As in F1 and F2 showed a positive correlation with the concentrations of As in polished rice. Therefore soil pH and available phosphorus affect the distribution of As fractionation in soils and thus affect As bioavailability.

• Journal of Embryo Transfer
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• v.33 no.4
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• pp.297-304
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• 2018

The purpose of the present study was to determine the elaborate characteristics of ovarian changes including follicles and corpus luteum, and hormonal patterns of gonadotropin surge mode secretions during the normal consecutive estrous cycle in three dairy cows. Non-lactating and multiparous Holstein cows (n=3) used as experimental animals. The cows were assigned to examine the relationship among ovarian changes (follicle, corpus luteum), ovarian steroids (estradiol, progesterone) and gonadotropin (LH, FSH) surge mode secretion during the successive estrous cycles by rectal palpation, ultrasonography and hormonal assay. The mean length of the estrous cycle for the three cows was $23.1{\pm}1.44days$ (${\pm}SEM$), with a range of 20-28 days. In six estrous cycles, the number of two follicular waves, three follicular waves and four follicular waves was 2, 3 and 1, respectively. The sequential ultrasonographic monitoring showed that the corpus luteum with ${\geq}10mm$ in diameter detected from Day 2 (Day 0 is ovulation) in six estrous cycles of all cows. Preovulatory increases in estradiol concentration reached $10.36{\pm}1.10pg/ml$ on the 2 days before ovulation of the last dominant follicle. All cows exhibited a preovulatory rise in estradiol concentration followed by a typical preovulatory LH and FSH surge. The mean interval from the peak of LH/FSH surge to ovulation of the last dominant follicle was $31.3{\pm}1.76h$ (${\pm}SEM$). In these results, each dairy cow showed that ovarian morphological changes and gonadotropin surge mode secretion will be regulated by various environmental factors including age, breeds, nutrition, breeding conditions, etc.