• Title/Summary/Keyword: Septic

Search Result 393, Processing Time 0.025 seconds

Clinical evaluation of traumatic diaphragmatic ruptures (외상성 횡격막 파열에 대한 임상적 고찰)

  • 유웅철
    • Journal of Chest Surgery
    • /
    • v.26 no.10
    • /
    • pp.791-797
    • /
    • 1993
  • We evaluated forty cases of traumatic diaphragmatic ruptures that we have experienced from Mar. 1976 to Mar. 1992. Thirty patients were male and 10 were female[M:F=3:1]. The age distribution was ranged from 2 to 76 years with the mean age of 35 years. The traumatic diaphragmatic ruptures were due to blunt trauma in 26 cases[traffic accident 20, fall down 4, others 2] and penetrating trauma in 14 cases[stab wound 13, gun shot 1]. In the blunt trauma, 21 of 26 cases were diagnosed within 24 hours after injury and all cases except one in penetrating trauma were diagnosed within 24 hours. In the blunt trauma, the rupture site was located in the left in 20 cases and in the right in 6 cases. In the penetrating trauma, the rupture site was located in the left in 10 cases and in the right in 4 cases. The repair of 40 cases were performed with thoracic approach in 19 cases, thoracoabdominal approach in 17 cases and abdominal approach in 4 cases. The postoperative mortality was 7.5 %[3/40]. The causes of death were septic shock[1], acute renal failure[1] and hypovolemic shock[1].

  • PDF

Review of 5-year Experimental Data from Treatment Wetland (인공습지 실험시설의 5년간 결과 및 고찰(지역환경 \circled3))

  • 김민희;윤춘경
    • Proceedings of the Korean Society of Agricultural Engineers Conference
    • /
    • 2000.10a
    • /
    • pp.649-654
    • /
    • 2000
  • Field experiment was performed from August 1996 to June 2000. The pilot plant was installed in Konkuk University and the effluent from septic tank of school building was used as an influent to the treatment basin. The treatment basin was composed of sand and reed. Average removal rate of BOD, SS was about 75.9%, 73.4%, respectively. T-P removal rate was about 47.3%, and T-N removal rate was 19.6%. The reason for poor T-N removal might be due to high influent concentration and short retention times. As operation period increased, BOD removal rates were increased, and SS and T-P removal rates did not change significantly, but T-N removal rates were decreased.

  • PDF

Inhibition of Nitric Oxide Synthesis by 8-epi-xanthatin in Activated RAW 264.7 Cells (활성화한 RAW 264.7 세포주에서 8-epi-xanthatin의 Nitric Oxide 생성저해)

  • Lee, Hwa-Jin;Jeong, Yeon-Su;Ryu, Shi-Yong;Ryu, Jae-Ha
    • YAKHAK HOEJI
    • /
    • v.42 no.5
    • /
    • pp.540-543
    • /
    • 1998
  • The nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase is known to be responsible for the vasodilation and hypotension observed in septic shock. We have found that 8-epi-xanthatin from Xanthium strumarium L. inhibited the production of NO in LPS-activated RAW 264.7 cells ($IC_{50}$ value was 1.5 ${\mu}$M). This activity was resulted from the suppressing of inducible nitric oxide synthase enzyme expression.

  • PDF

Design of Super Water-Saving Toilet System by Solving Physical Contradiction in Theory of Inventive Problem Solving (TRIZ) (창의적 문제 해결 기법의 물리적 모순 해결에 의한, 초절수형 양변기 시스템의 설계)

  • 이홍석;이경원
    • Korean Journal of Computational Design and Engineering
    • /
    • v.6 no.3
    • /
    • pp.193-197
    • /
    • 2001
  • This paper describes the design process of super water-saving toilet bowl system by the theory of inventive problem solving (TRIZ). The physical contradiction in TRIZ is defined far saving water in toilet bowl system with preventing the bad smell from septic tank. The super water-saving toilet bowl system is obtained by using the separation principle in time far resolving the physical contradiction. The real system is made using CAD tools. The consumption of water in the system implemented, is estimated about 3 ιcomparing with 13 ι of that in conventional toilet bowl system.

  • PDF

Hepatic Metabolism of Sulfur Amino Acids During Septic Shock (패혈성 쇼크에서 간의 유황함유 아미노산 대사)

  • Kang, Keon-Wook;Kim, Sang-Kyum
    • YAKHAK HOEJI
    • /
    • v.51 no.6
    • /
    • pp.383-388
    • /
    • 2007
  • It has been reported that sulfur-containing intermediates or products in the transsulfuration pathway including S-adenosylmethionine, 5'-methylthioadenosine, glutathione and taurine can prevent liver injury mediated by inflammation response induced by lipopolysaccharide (LPS) treatment. The present study examines the modulation of hepatic metabolism of sulfur amino acid in a model of acute sepsis induced by LPS treatment (5 mg/kg, iv). Serum TNF-alpha and hepatotoxic parameters were significantly increased in rats treated with LPS, indicating that LPS results in sepsis at the doses used in this study. LPS also induced oxidative stress determined by increases in malondialdehyde levels and decreases in total oxy-radical scavenging capacities. Hepatic methionine and glutathione concentrations were decreased, but S-adenosylho-mocysteine, cystathionine, cysteine, hypotaurine and taurine concentrations were increased. Hepatic protein expression of methionine adenosyltransferase, cystathionine beta-synthase and cysteine dioxygenase were induced, but gamma-glutamylcysteine ligase catalytic subunit levels were decreased. The results show that sepsis activates transsulfuration pathway from methionine to cysteine, suggesting an increased requirement for methionine during sepsis.

A Case of Lemierre Syndrome (Lemierre 증후군 1예)

  • Kim, Ye-Won;Kim, Dong-Hyun;Kim, Do-Hyun;Jeon, Eun-Ju
    • Korean Journal of Bronchoesophagology
    • /
    • v.16 no.2
    • /
    • pp.149-153
    • /
    • 2010
  • Lemierre syndrome, also known as postanginal sepsis, is a severe complication of an acute oropharyngeal infection that result in septic thrombophlebitis of the internal jugular vein with subsequent septicemia. This disease is relatively rare, but it has significant morbidity and is potentially fatal. Early diagnosis based on computed tomography with contrast enhancement is mandatory and immediate treatment including intravenous antibiotics, anticoagulants, or surgical approach should be considered. We report a case of Lemierre syndrome after deep neck infection which was successfully treated using antibiotics and anticoagulants.

  • PDF

Yomogin, an Inhibitor of Nitric Oxide Production in LPS-Activated Macrophages

  • Ryu, Jae-Ha;Lee, Hwa-Jin;Jeong, Yeon-Su;Ryu, Shi-Yong;Han, Yong-Nam
    • Archives of Pharmacal Research
    • /
    • v.21 no.4
    • /
    • pp.481-484
    • /
    • 1998
  • In activated macrophages the inducible form of nitric oxide synthase (i-NOS) generates high amounts of toxic mediator, nitric oxide (NO) which contributes to the circulatory failure associated with septic shock. A sesquiterpene lactone compound (yomogin) isolated from medicinal plant Artemisia princeps Pampan inhibited the production of NO in LPS-activated RAW 264.7 cells by suppressing i-NOS enzyme expression. Thus, yomogin may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO.

  • PDF

Clinical Year in Review 2014: Critical Care Medicine

  • Lee, Jeong Moon;Lee, Heung Bum
    • Tuberculosis and Respiratory Diseases
    • /
    • v.77 no.1
    • /
    • pp.6-12
    • /
    • 2014
  • Severe sepsis is the most common cause of death among critically ill patients in non-coronary intensive care units. In 2002, the guideline titled "Surviving Sepsis Campaign" was published by American and European Critical Care Medicine to decrease the mortality of severe sepsis and septic shock patients, which has been the basis of the treatment for those patients. After the first revised guidelines were published on 2008, the most current version was published in 2013 based on the updated literature of until fall 2012. Other important revised guidelines in critical care field such as 'Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit' were revised in 2013. This article will review the revised guidelines and several additional interesting published papers of until March 2014, including the part of ventilator-induced lung injury and the preventive strategies.

Spontaneous Uterine Rupture in a Greyhound Bitch during Parturition

  • Park, Chul-Ho;Oh, Ki-Seok;Son, Chang-Ho
    • Journal of Embryo Transfer
    • /
    • v.29 no.4
    • /
    • pp.393-395
    • /
    • 2014
  • A 6-year old, Greyhound bitch was presented with vaginal hemorrhage and dystocia. Physical examination revealed severe vaginal hemorrhage, abdominal pain, pale mucous membranes and the presence of solid structures to abdominal palpation. A hematological test revealed a marked hemorrhagic anemia, and abdominal radiography and ultrasonographic examination showed two dead fetuses in the uterus. Median laparotomy revealed a rupture of the left uterine horn adjacent to the bifurcation, region of weakened uterine wall in the right uterine horn, blood clots and uterine fluids in abdominal cavity without septic peritonitis. The bitch underwent ovariohysterectomy and recovered without complication.

A Study on the Small Wastewater Collection System for Rural Area (농촌지역 소규모 오수차집시스템에 관한 연구)

  • Yoon, Chun-Gyeong;Yoo, Chan
    • Journal of Korean Society of Rural Planning
    • /
    • v.4 no.2
    • /
    • pp.20-28
    • /
    • 1998
  • A small wastewater collection system for rural area was reviewed and the small diameter gravity (SDG) was thought to be the most appropriate. The pilot-scale field experiment was performed for 15 months and the result is presented. The wastewater used for experiment was the effluent of septic tank in Kon-Kuk University, and components are similar to normal domestic wastewater. The SDG experimental system included 2" PVC pipe and reverse-sloped lower section is included. No clogging problem by solids was experienced at the points where flow direction changed. The pipe-breaking by freezing was experienced during the cold weather, thus proper protection may be required where severe weather is expected.

  • PDF