• KSBB Journal
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• 제23권2호
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• pp.135-141
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• 2008

SMB 크로마토그래피를 위한 예비 실험으로서 L-ribose와 L-arabinose의 혼합물의 분리 특성을 $NH_2$ 컬럼을 사용하여 확인하였고 두 성분 분리 최적 조건으로 Acetonitrile과 증류수의 조성이 85/15 (v/v)에서 실험을 수행하였다. PIM(Pulse input method)과 Aspen chromatography 전산모사를 통해 L-ribose와 L-arabinose가 선형 흡착등온식을 따르는 것을 알 수 있었으며 각 성분의 Henry상수를 추산하였고 다음과 같다. $$C_{S,Ribose}=3.51{\cdot}C_{M.Ribose}$$ $$C_{S,Arabinose}=5.07{\cdot}C_{M.Arabinose}$$ 이를 바탕으로 SMB 크로마토그래피의 최적 운전조건을 수립하기 위하여 Triangle 이론에 의한 운전 조작변수를 추산함으로서 $m_2\;=\;3.51$, $m_3\;=\;5.07$일 때 즉, 삼각형에서 꼭지점의 조건에서 L-ribose와 L-arabinose의 순도가 각각 85, 80% 정도로 두 성분의 분리에 있어서 가장 효과적인 운전 조건임을 확인 할 수 있었다.

• Fisheries and Aquatic Sciences
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• 제20권7호
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• pp.13.1-13.7
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• 2017

In order to evaluate the maximal storable period of the raw crab for a non-thermal muscle separation, the quality changes of the leg meat of red snow crab (Chionoecetes japonicus) during freeze storage were investigated. Fresh red snow crabs were stored at $-20^{\circ}C$ for 7 weeks, and the leg muscle was separated by a no heating separation (NHS) method every week. During the storage, considerable loss of the leg muscle did not occur and microbiological risk was very low. In contrast, discoloration appeared at 2-week storage on around carapace and the leg muscle turned yellow at storage 3-week. In physiochemical parameters, protein and free amino acids gradually decreased with storage time, expected that proteolytic enzymes still activated at $-20^{\circ}C$. At 4-week storage, the sensory acceptance dropped down below point 4 as low as inedible and notable inflection points in pH and acidity were observed. The volatile base nitrogen was low, though a little increase was recorded. These results suggested that the maximal storable period at $-20^{\circ}C$ of the raw material was within 2 weeks and it was depended on external factor such as the discoloration. The present study might be referred as basic data for approaches to solve quality loss occurred in non-thermal muscle separation.

• 멤브레인
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• 제16권3호
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• pp.204-212
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• 2006

이산화탄소에 대한 가소화 안정성 및 이산화탄소/질소의 분리특성이 탁월한 폴리이서술폰(PES)중공사 분리막에 의한 이산화탄소 분리특성을 수치해석으로 알아보고자 하였다. 공정변수에 따른 이산화탄소 분리 거동을 예측하기 위하여 공급 기체와 투과기체가 같은 방향으로 흐르는 병류 흐름에 대한 분리막 공정 지배 방정식을 5차 Runge-Kutta-Verner 방법을 사용하여 Compaq Visual Fortran 6.6 소프트웨어를 이용 공정모사 프로그램을 개발하였다. 개발된 프로그램을 사용하여 수치해석을 수행한 결과, 이산화탄소 투과특성에 영향을 주는 가장 중요한 인자로서 공급 이산화탄소 분압, 투과측과 분리막 내부의 압력비 그리고 공급 기체가 분리막 내부에 머무르는 체류 시간임을 알 수 있었다.

• 한국구조물진단유지관리공학회 논문집
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• 제21권1호
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• pp.100-108
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• 2017

최근에 도시화와 산업화 및 교통망의 지속적인 확보로 인하여 발파공사를 시행하는 공사장이 증가하고 있다. 발파공사는 주변 주민들의 주거환경과 인접시설물들의 안전에 큰 영향을 미치므로 이에 대한 대책이 필요하다. 본 연구에서는 발파피해를 줄이기 위한 방법 중에서 발파공내의 발파메커니즘을 규명하고 개선하였다. 일반적인 공법에서 발생하는 천공경과 폭약경 사이의 차이로 인한 공간에서 디커플링효과를 규명하고, 이 공간의 매질을 변화시킴으로서 발파 시 진동발생의 규모를 규명하였다. 발파시험은 도로, 철도, 산업단지에서 실시하고, 발파진동을 측정하였다. 측정된 진동속도를 회귀분석하여 발파진동추정식을 산정하고 이를 이용하여 이격거리를 산정하였다. 공내 매질이 공기보다는 물처럼 비중이 큰 경우에 충격력은 크나 폭발 지연시간이 짧아 진동전달거리가 작아 이격거리를 크게 확보할 수 있다.

• KSBB Journal
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• 제20권3호
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• pp.244-249
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• 2005

Kromasil HR100-5CHI-TBB 칼럼을 사용하여 HPLC를 통한 비스테로이드 계통의 진통 및 소염제인 racemic ibuprofen의 분리특성을 연구하였다. 이동상의 조성비 변고에 따른 분리도 (resolution), 이론단수 (number o( theoretical plates), 이론단 높이 (HETP: Height Equivalent to a Theoretical Plate), 용량인자 (capacity factor)를 계산하고, 그 결과 정성분석 기준치 이상의 분리도를 갖고 분리시간을 단축할 수 있는 hexane /t-BME의 조성이 55 / 45일 때 $1\%$의 acetic acid를 첨가했을 때의 용매를 최적의 이동상으로 결정했다. 유속에 따른 칼럼의 효율을 비교하기 위한 실험을 통해 유속의 상승은 칼럼의 효율의 감소를 야기하고, 분리도를 감소시킴을 보였다. PIM (Pulsed Input Method)을 사용하여 분석한 결과 ibuprofen 의 농도가 증가할수록 Langmuir 등온흡착식을 따르는 비선형 거동을 보임을 증명하였고, 그 결과 등온흡착식을 결정하였다. 등온흡착식은 S-form과 R-form의 경우 각각 $C_{S,S}=\frac{1.178C_{M,S}}{1+0.019C_{M,S}},\;C_{S,R}=\frac{1.866C_{M,S}}{1+0.017C_{M,S}}$로 결정하였다.

• 청정기술
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• 제13권1호
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• pp.79-84
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• 2007

본 연구에서는 Ag가 포함된 sulfonated poly(ether ether ketone) (SPEEK)를 촉진 수송 분리막으로 사용하여 에틸렌/에탄 그리고 프로필렌/프로판의 분리연구를 수행하였다. SPEEK는 PEEK를 황산과 반응시켜 제조할 수 있는데, 제조 방법에 따라 다양한 설폰화도 (DS)을 나타내었고 약 70시간 반응시켰을 때 0.95의 DS값을 보여주었다. SPEEK의 농도를 변화시켜 제조된 막은 각각 다른 두께로 코팅됨을 SEM으로 확인하였다. SPEEK막에 Ag 염 수용액을 반응시켜 제조한 SPEEK-Ag 막을 이용하여 에틸렌/에탄 그리고 프로필렌/프로판의 분리 실험을 실시한 결과 에틸렌과 프로필렌은 SPEEK 코팅 두께에 따라 $200{\sim}500$의 선택도를 보여 주었고, 투과도는 $5{\sim}50$ GPU값을 보여 주었다. 또한 SPEEK-Ag 촉진 수송막은 막을 제조할 때 사용한 은염의 종류에 따라서도 각기 다른 분리 효율을 나타내었다.

• 대한치과기공학회지
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• 제12권1호
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• pp.15-21
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• 1990

This research was to investigate and study on 92 Dental Technicians who had had some experience of working or being employed at dental craft-shops or craft-rooms in Seoul area and had transferred to other types of occupation, with regard to their reasons for changing their profession. For an approach to the study, some questionnaires and interview including 3 aspects of in quiriesmental, economic and social backgrounds-were administered, and major findings are as follows ; 1. The ages in which transferring to other kinds of job happened occurred mostly from 20 to 30(78.26%) an a group of subjects whose ages ranged from 20 to 30 years old. And, with regard to their experience of working or being employed at dental craft-shops or craftrooms, the transfer of their profession to the other kinds mosty happened in a group of subjects(94.56%) whose experience of working in the dental field is less than 4 years. 2. The reason of transfer with reference to the mental background was mostly mattered in a group that expressed "Excessive Work Duties"(34.78%), and most lowly mattered in a group of subjets who had "Certain Relations with Dentists"(8.70%). Thus, it appeared that the biggest reason of transfer by the mental background was, due to the excessive duty work, not to have Sufficient time to be usualized by dental technicians for their own purpose. 3. With reference to the economical background, a group that declared there was "No Wage Standards in Ratio to Their Labor" was the most in the separation rate as shown 45.56%. And, a group suspecting "No Guarantee for Their Living after Retirement" Showed a separation rate, 9.78%. In other words, the reason for transfer was that they did not receive due wage according to their amount of labor. 4. With reference to the social background, a group making a subject for no good working environments or conditions had a separation rate, 41.30%, which was the most among others, and a group with a subject of "The Rarity of Employment because of Excessive Supply of Dental Technicians" had the rate, 10.87%, which was the lowest. This meant that the major cause of transfer by the social background was a phenomenon for dental technicans to escape from unclean working places.

• Journal of Ginseng Research
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• 제44권5호
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• pp.680-689
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• 2020

Background: Peptides have diverse and important physiological roles in plants and are ideal markers for species identification. It is unclear whether there are specific peptides in Panax quinquefolius L. (PQ). The aims of this study were to identify Quinetides, a series of diverse posttranslational modified native peptides of the ribonuclease-like storage protein (ginseng major protein), from PQ to explore novel peptide markers and develop a new method to distinguish PQ from Panax ginseng. Methods: We used different fragmentation modes in the LTQ Orbitrap analysis to identify the enriched Quinetide targets of PQ, and we discovered Quinetide markers of PQ and P. ginseng using ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry analysis. These "peptide markers" were validated by simultaneously monitoring Rf and F11 as standard ginsenosides. Results: We discovered 100 Quinetides of PQ with various post-translational modifications (PTMs), including a series of glycopeptides, all of which originated from the protein ginseng major protein. We effectively distinguished PQ from P. ginseng using new "peptide markers." Four unique peptides (Quinetides TP6 and TP7 as markers of PQ and Quinetides TP8 and TP9 as markers of P. ginseng) and their associated glycosylation products were discovered in PQ and P. ginseng. Conclusion: We provide specific information on PQ peptides and propose the clinical application of peptide markers to distinguish PQ from P. ginseng.

• 지역사회간호학회지
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• 제11권2호
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• pp.513-525
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• 2000

This study was to investigate medication management and the level of awareness about separation of prescribing and dispending at small-to-medium sized workplaces which have less than 300 employees in Korea. The data were collected by questionnaires from May to June in 2000. The number of subjects were 127 workplaces and 130 employees. The SAS PC Program was used for the descriptive statistics. The results are as follows; 1. The over the counter(OTC) drug was provided sufficiently(91.1 %). but medication management was not performed systematically. 2. On drug-providing rate and drug-using rate, the latter was high in the workplace and Health care management's nurses consume all of the over the counter drug provided. 3. When the separation of prescribing and dispending starts, employees shall be medically examined, treated and prescribed by physicians and drugs shall be dispended by pharmacists. It is necessary to make it possible to visit health care institutions whenever they want to. (eg. lunch time or after work) They should change their drug-dependent behaviour. We should focus on strengthening Health Promotion Program to prevent disease by making habitual of health promotion behaviour.

• Design & Manufacturing
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• 제11권2호
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• pp.29-36
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• 2017

In this study, the non-contact type bicycle generator system considering the recharge is developed to use the eco-friendly energy source when the bicycle is operating. The following three main factors are considered in this study. One of factors is that the intensity of the rotating magnet is in the range of 2,700~4,300 [Gause]. The next factor is that the separation distance of rotating magnet and bicycle rim is in the range of 1.5-3.0 mm. The last factor is that the pedaling speed is in the range of 55 RPM [Wheel speed 5.6Km]~150 RPM [Wheel speed 15.25Km] consirering with the 5 staged gear transmission. The obtained results are as followed. (1) The generator output voltage gradually increases from 3V to 10V with the pedaling speed increases, at the separation distance is less than 2.5 mm and the operating voltage of the LED lamp is generated at a pedaling speed of 60 RPM or more. (2) The output current of the generator increases from 20mA to 40mA with the pedaling speed increases, at a separation distance is less than 2.0 mm and the operating current of the LED lamp is generated at a pedaling speed of 60 RPM or more. (3) When the separation distance was 3.0 mm, the output voltage and current are significantly lower than those of the bicycle LED lamp is generated. (4) The charging time is expected to be 12.24 ~ 17.65 hours when the magnitude of the magnet is 3,400[Gauss] at a pedaling speed of 55 RPM or more. (5) As a result of this study, it is thought that the non-contact type bicycle generator system considering the recharge can replace the conventional friction power generation system.