• Title/Summary/Keyword: Seong-Ho School

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Effect of Rhizoma gastrodiae on oxidative stress in cultured mouse spinal motor neurons

  • Park, Seung-Taeck;Kim, Jeong-Joong;Jeong, Se-Jin;Cho, Chung-Gu;Lee, Kang-Chang;Jang, Chul-Ho;Park, Jae-Hwang;Hong, Gi-Youn;Yoon, Hyang-Suk;Oh, Yeon-Kyun;Oh, Kwang-Su;Min, Bu-Kie;Han, Du-Seok;Baek, Seung-Hwa;Chun, Seung-Ho;Lee, Gap-Sang;Lee, Seong-Keun;Seong, Kang-Kyung;Lee, Geon-Mok;Jeon, Byung-Hoon;Song, Ho-Jun
    • Advances in Traditional Medicine
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    • v.1 no.2
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    • pp.59-65
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    • 2000
  • To clarify the toxic effect of oxidative stress, hydrogen peroxide $(H_{2}O_{2})-induced$ neurotoxicity was examined in cultured newborn mouse spinal motor neurons after spinal motor neurons were grown in the media containing various concentrations of glucose oxidase (GO). And also, the protective effect of Rhizoma gastrodiae extract against GO-induced neurotoxicity was evaluated. Cytotoxicity was expressed as a cell viability by 3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide (MTT) assay. In this study, exposure of motor neurons to GO-induced cell death significantly, in a dose- and time-dependent manners in spinal motor neuron cultures. The decrease in cell viability of motor neurons damaged by GO was proventioned by Rhizoma gastrodiae extract. These results suggest that the neuroprotective effect of Rhizoma gastrodiae extract on GO-induced neurotoxicity may result from a attenuation of $H_{2}O_{2}-induced$ oxidative stress.

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Implementation of Area-based stereo algorithm on SoC based on ARM core (ARM platform 기반의 스테레오 비전 SoC 설계)

  • Chang, Ji-Ho;Lee, Ho-Young;Kim, Jun-Seong;Morris, John
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.703-706
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    • 2005
  • 본 논문에서는 스테레오 비전 알고리즘을 ARM9 프로세서를 사용하는 SoC의 IP 개념으로 구현하였다. 구현하고자 하는 스테레오 비전 시스템을 기능에 따라서 하드웨어와 소프트웨어 모듈로 나누어서 성능을 최대화할 수 있도록 설계하였다. SAD correlator는 한 쌍의 이미지에 많은 계산을 필요로 하기 때문에 성능을 우선시하여 하드웨어로 구성하였고, 소프트웨어는 프로세서를 초기화 시키고, 인터럽트 처리와 SAD correlator, TFT-LCD controller, 메모리 등의 하드웨어를 제어하는 역할을 하는 firmware로 구성을 하였다. 메모리에 기저장된 영상정보를 스테레오 비전 알고리즘을 이용한 결과를 외부 TFT-LCD 모듈에서 필요로 하는 포맷에 맞게 변환시켜서 depth map을 출력하는 시스템을 ARM922T 프로세서가 내장된 Altera Excalibur를 target으로 설계하여 테스트 보드에서 정상적으로 동작하는 것을 확인하였다.

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Lithospermic acid modulate the Action potential duration by increasing Ica current in the rat ventricular myocyte

  • An, Seong-Hun;Kang, Dae-Gill;Lee, Ho-Sup;Lee, Suk-Ho;Earm, Yung-E
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.55-55
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    • 2001
  • We observed the APD of rat ventricle myocyte and the effects of Lithospermic acid that was separated at Salvia miltiorrhiza having used in Oriental medicine by using classical whole cell patch clamp technique. We classified APD into APD30mV, APD0mV, APD-50mV, APD-60mV by cell membrane potential and the mean of cell resting membrane potential was -69.44${\pm}$1.72 mV.(omitted)

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Harmonic Wavelet Method for Minimizing Relative Error (상대 오차의 최소화를 위한 조화 웨이블릿 기법)

  • Ham, Sung-Ho;Kang, Seong-Goo;Lee, Suk-Ho
    • Proceedings of the Korean Information Science Society Conference
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    • 2005.07b
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    • pp.91-93
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    • 2005
  • 대용량 데이타에 대한 복잡한 질의 처리가 요구되는 응용에서 빠른 시간 안에 응답을 돌려주기 위해, 데이타를 작은 크기로 근사하여 질의를 처리하는 방법이 연구되고 있다. 빠른 응답을 위해 주어진 저장 공간의 제약 하에서 얼마나 원본 데이타와 유사하게 근사할 수 있는지가 데이타 근사의 성능을 결정한다. 본 논문에서는 데이타 근사에서 유사도의 척도 중 하나인 최대 상대 오차를 줄이기 위하여 Haar 웨이블릿을 변형한 조화 웨이블릿 기법을 제안한다. 조화 웨이블릿은 데이타 변환 과정 중 조화평균을 이용하여 상대 오차 정보를 손쉽게 얻어낼 수 있어 근사 데이타의 상대 오차를 최소화하는 데 적합한 기법이다.

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Finding Report of Unilateral Vocal Cord Paralysis Using Computed Tomography (컴퓨터단층촬영술을 이용한 수술 후 편측 성대마비의 진단보고)

  • Kim, Minsoo;Seong, Hyun Ho;Kang, Seong Sik;Son, Hee Jeong;Kim, Tae-Hyung;Cheong, Yuseon
    • Journal of radiological science and technology
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    • v.41 no.5
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    • pp.505-509
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    • 2018
  • VCP (Vocal Cord Paralysis) is rare but one of most serious complications related to endotracheal intubation. This report is a clinical experience of radiography and laryngeal EMG (Electromyography) assessment for the VCP. A 50-year-old woman with hoarseness, which was occurred after urethral diverticulum excision was examined by laryngoscopy. As a result of laryngoscopy, VCP was observed in left side of her vocal cord, and then recurrent laryngeal nerve damage was detected with additional CT (Computed tomography) scan and laryngeal EMG. After that, the vocal cord movement was recovered as normal state with regular conservative treatment for the 6 months.

Implementation of ECG Measurement Application Based on Android (안드로이드 기반의 심전도 측정 어플리케이션 구현)

  • Park, Byeong-Ho;Jang, Seong-Won;Heo, Beom;Park, Sang-Ju;Seong, Hyeon-Kyeong
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2011.06a
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    • pp.67-70
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    • 2011
  • 본 논문에서는 고성능 컴퓨팅 시스템의 성능 향상을 위한 효율적인 동적 작업부하 균등화 정책을 제안한다. 이 정책은 시스템 자원인 CPU와 메모리를 효율적으로 사용하여 고성능 컴퓨팅 시스템의 처리량을 최대화하고, 각 작업의 수행시간을 최소화한다. 또한 이 정책은 수행중인 작업의 메모리 요구량과 각 노드의 부하 상태를 파악하여 작업을 동적으로 할당한다. 이때 작업을 할당 받은 노드가 과부하 상태가 되면 다른 노드로 작업을 이주시켜 각 노드의 작업부하를 균등하게 유지함으로써 작업의 대기시간을 줄이고, 각 작업의 수행시간을 단축한다. 본 논문에서는 시뮬레이션을 통하여 제안하는 동적 작업부하 균등화 정책이 기존의 메모리 기반의 작업부하 균등화 정책에 비해 고성능 컴퓨팅 시스템의 성능 향상 면에서 우수함을 보인다.

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Sensorimotor Polyneuropathy and Multiple Cranial Neuropathies Associated with IgG κMonoclonal Gammopathy of Undetermined Significance (IgG κMonoclonal Gammopathy of Undetermined Significance와 연관된 운동신경 다발성 신경병증과 다발선 뇌신경병증)

  • Jeon, Seong-Ho;Kim, Yoon-Bong;Lee, Yeong-Bae;Park, Jong-Ho;Shin, Won-Chul;Park, Hyeon-Mi;Shin, Dong-Jin
    • Annals of Clinical Neurophysiology
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    • v.6 no.1
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    • pp.48-51
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    • 2004
  • The occurrence of polyneuropathy in association with monoclonal gammopathy of undetermined significance (MGUS) is quite common. However, reports of MGUS associated cranial neuropathies are rare. A 63 year-old women was presented with diplopia and swallowing difficulty. Neurological examination showed limitation of abduction of right eye, right peripheral facial palsy, decreased hearing and gag reflex, left side deviation of uvula, and decreased DTR. Sensorimotor polyneuropathy were observed with elctrophysiological studies. Protein and immunoelectrophoresis revealed IgG ${\kappa}$monoclonal gammopathy. She was treated with intravenous immunoglobulin and steroid, and her symptoms and signs were improved. This case suggested that she had sensorimotor polyneuropathy and multiple cranial neuropathies associated with IgG ${\kappa}$MGUS.

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Effects of CrN and TiN Coating by Hydrogen Embrittlement of Aluminum Alloys for Hydrogen Valves of Hydrogen Fuel Cell Vehicles on Mechanical Properties (수소연료전지 자동차의 수소밸브용 알루미늄 합금의 수소취화에 의한 기계적 특성에 미치는 CrN과 TiN 코팅의 영향)

  • Ho-Seong Heo;Dong-Ho Shin;Seong-Jong Kim
    • Corrosion Science and Technology
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    • v.22 no.4
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    • pp.232-241
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    • 2023
  • The mechanical properties of the hydrogen valve responsible for supplying and blocking hydrogen gas in a hydrogen fuel cell electric vehicle (FCEV) were researched. Mechanical properties by hydrogen embrittlement were investigated by coating chromium nitride (CrN) and titanium nitride (TiN) on aluminum alloy by arc ion plating method. The coating layer was deposited to a thickness of about 2 ㎛, and a slow strain rate test (SSRT) was conducted after hydrogen embrittlement to determine the hydrogen embrittlement resistance of the CrN and TiN coating layers. The CrN-coated specimen presented little decrease in mechanical properties until 12 hours of hydrogen charging due to its excellent resistance to hydrogen permeation. However, both the CrN and TiN-coated specimens exhibited deterioration in mechanical properties due to the peeling of the coating layer after 24 hours of hydrogen charging. The specimens coated at 350 ℃ presented a significant decrease in ultimate tensile strength due to abnormal grain growth.