• 제목/요약/키워드: Sentinel

검색결과 415건 처리시간 0.027초

Prospective Multicenter Feasibility Study of Laparoscopic Sentinel Basin Dissection after Endoscopic Submucosal Dissection for Early Gastric Cancer: SENORITA 2 Trial Protocol

  • Eom, Bang Wool;Yoon, Hong Man;Min, Jae Seok;Cho, In;Park, Ji-Ho;Jung, Mi Ran;Hur, Hoon;Kim, Young-Woo;Park, Young Kyu;Nam, Byung-Ho;Ryu, Keun Won;Sentinel Node Oriented Tailored Approach (SENORITA) Study Group
    • Journal of Gastric Cancer
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    • 제19권2호
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    • pp.157-164
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    • 2019
  • Purpose: Although standard radical gastrectomy is recommended after noncurative resection of endoscopic submucosal dissection (ESD) for early gastric cancer in most cases, residual tumor and lymph node metastasis have not been identified after surgery. The aim of this study is to evaluate the feasibility of sentinel node navigation surgery after noncurative ESD. Materials and Methods: This trial is an investigator-initiated, multicenter prospective phase II trial. Patients who underwent ESD for clinical stage T1N0M0 gastric cancer with noncurative resections were eligible. Qualified investigators who completed the prior phase III trial (SENORITA 1) are exclusively allowed to participate. In this study, 2 detection methods will be used: 1) intraoperative endoscopic submucosal injection of dual tracer, including radioisotope and indocyanine green (ICG) with sentinel basins detected using gamma-probe; 2) endoscopic injection of ICG, with sentinel basins detected using a fluorescence imaging system. Standard laparoscopic gastrectomy with lymphadenectomy will be performed. Sample size is calculated based on the inferior confidence interval of the detection rate of 95%, and the calculated accrual is 237 patients. The primary endpoint is detection rate, and the secondary endpoints are sensitivity and postoperative complications. Conclusions: This study is expected to clarify the feasibility of laparoscopic sentinel basin dissection after noncurative ESD. If the feasibility is demonstrated, a multicenter phase III trial will be initiated to compare laparoscopic sentinel node navigation surgery versus laparoscopic standard gastrectomy in early gastric cancer after endoscopic resection.

의료기관 내 자살사건의 근본원인분석과 개선전략 (Root cause analys is and improving strategy of suicidal sentinel events)

  • 임헌선;김홍순;염호기
    • 한국의료질향상학회지
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    • 제19권2호
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    • pp.50-64
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    • 2013
  • Objectives : Suicide is a serious sentinel event in healthcare organization. Suicide and suicidal attempt are fatal and long lasting mental and physical damage to themselves, family, and medical staffs. To develope the system to prevent suicidal accident in hospital, we reviewed and analysed one case of suicidal sentinel event. Methods: The risks of suicidal sentinel event were evaluated and analysed through the root cause analysis and failure mode effects analysis. Result: We found several root causes such as initial assessment of oldest patient and security issues. Couple of action plans to fix the problems were done immediately. According to failure mode, we evaluate the risk priority number to modify the action plans. Conclusion: To reduce the risk of sentinel events, we reviewed the suicidal event and established the new system and action plan to prevent sentinel events.

The Potential of Sentinel-1 SAR Parameters in Monitoring Rice Paddy Phenological Stages in Gimhae, South Korea

  • Umutoniwase, Nawally;Lee, Seung-Kuk
    • 대한원격탐사학회지
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    • 제37권4호
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    • pp.789-802
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    • 2021
  • Synthetic Aperture Radar (SAR) at C-band is an ideal remote sensing system for crop monitoring owing to its short wavelength, which interacts with the upper parts of the crop canopy. This study evaluated the potential of dual polarimetric Sentinel-1 at C-band for monitoring rice phenology. Rice phenological variations occur in a short period. Hence, the short revisit time of Sentinel-1 SAR system can facilitate the tracking of short-term temporal morphological variations in rice crop growth. The sensitivity of SAR backscattering coefficients, backscattering ratio, and polarimetric decomposition parameters on rice phenological stages were investigated through a time-series analysis of 33 Sentinel-1 Single Look Complex images collected from 10th April to 25th October 2020 in Gimhae, South Korea. Based on the observed temporal variations in SAR parameters, we could identify and distinguish the phenological stages of the Gimhae rice growth cycle. The backscattering coefficient in VH polarisation and polarimetric decomposition parameters showed high sensitivity to rice growth. However, amongst SAR parameters estimated in this study, the VH backscattering coefficient realistically identifies all phenological stages, and its temporal variation patterns are preserved in both Sentinel-1A (S1A) and Sentinel-1B (S1B). Polarimetric decomposition parameters exhibited some offsets in successive acquisitions from S1A and S1B. Further studies with data collected from various incidence angles are crucial to determine the impact of different incidence angles on polarimetric decomposition parameters in rice paddy fields.

Sentinel-1 SAR 위성영상과 Water Cloud Model을 활용한 시공간 토양수분 산정 (Spatio-temporal soil moisture estimation using water cloud model and Sentinel-1 synthetic aperture radar images)

  • 정지훈;이용관;김세훈;장원진;김성준
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2022년도 학술발표회
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    • pp.28-28
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    • 2022
  • 본 연구는 용담댐유역을 포함한 금강 유역 상류 지역을 대상으로 Sentinel-1 SAR (Synthetic Aperture Radar) 위성영상을 기반으로 한 토양수분 산정을 목적으로 하였다. Sentinel-1 영상은 2019년에 대해 12일 간격으로 수집하였고, 영상의 전처리는 SNAP (SentiNel Application Platform)을 활용하여 기하 보정, 방사 보정 및 Speckle 보정을 수행하여 VH (Vertical transmit-Horizontal receive) 및 VV (Vertical transmit-Vertical receive) 편파 후방산란계수로 변환하였다. 토양수분 산정에는 Water Cloud Model (WCM)이 활용되었으며, 모형의 식생 서술자(Vegetation descriptor)는 RVI (Radar Vegetation Index)와 NDVI (Normalized Difference Vegetation Index)를 활용하였다. RVI는 Sentinel-1 영상의 VH 및 VV 편파자료를 이용해 산정하였으며, NDVI는 동기간에 대해 10일 간격으로 수집된 Sentinel-2 MSI (MultiSpectral Instrument) 위성영상을 활용하여 산정하였다. WCM의 검정 및 보정은 한국수자원공사에서 제공하는 10 cm 깊이의 TDR (Time Domain Reflectometry) 센서에서 실측된 6개 지점의 토양수분 자료를 수집하여 수행하였으며, 매개변수의 최적화는 비선형 최소제곱(Non-linear least square) 및 PSO (Particle Swarm Optimization) 알고리즘을 활용하였다. WCM을 통해 산정된 토양수분은 피어슨 상관계수(Pearson's correlation coefficient)와 평균제곱근오차(Root mean square error)를 활용하여 검증을 수행할 예정이다.

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랜덤포레스트와 Sentinel-2를 이용한 식생 분류의 입력특성 최적화 (Optimization of Input Features for Vegetation Classification Based on Random Forest and Sentinel-2 Image)

  • 이승민;정종철
    • 한국지리정보학회지
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    • 제23권4호
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    • pp.52-67
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    • 2020
  • 최근 북극은 매년 영구 동토층이 녹아 눈으로 덮인 땅이 드러나고 있어 해당 지역 관리를 위한 공간정보가 필요하다. 한국의 국토지리정보원(NGII)은 극지방의 공간정보를 구축하여 극지공간정보 서비스를 제공하고 있으나, 식생 정보는 제공되지 않고 있으므로 식생 공간정보 구축을 위한 추가적인 연구가 필요하다. 본 연구에서는 북극 스발바르제도의 뉘올레순 지역에 대한 식생 분류를 수행하기 위해 다중 시기의 Sentinel-2 영상을 사용하였다. 전처리 단계에서는 다중 시기 Sentinel-2 영상으로부터 10개 밴드와 6가지 정규 지수식을 생성하였다. 영상 분류는 8개 속성에 대한 토지피복분류를 통해 전체 식생 영역을 추출하는 과정과 전체 식생 영역 내에서 다시 세분류를 수행하는 과정으로 이루어졌다. 영상 분류 알고리즘은 OOB(Out-Of-Bag)를 통해 정확도 평가 및 변수 중요도를 산정할 수 있는 랜덤포레스트를 사용하였다. 전체 정확도는 다시기 영상이 사용되었을 경우와 식생 지수가 추가되었을 경우의 이점을 확인하기 위해 사용된 영상 수에 따라 각각 정확도를 산정하였다. 단일시기의 Sentinel-2 영상은 전체 정확도가 77%였으나, 7개의 다중 시기 Sentinel-2 영상을 기반으로 학습하였을 때, 81%로 향상되었다. 또한, 식생 지수가 추가로 사용된 학습에서 전체 정확도가 약 83%로 향상되었다. 식생 분류 시 변수 중요도는 적색, 녹색, 단파적외선-1 밴드가 가장 높은 변수로 선정되었다. 본 연구는 극지방의 식생에 대한 분류를 수행할 시 입력특성을 최적화하는 기초 연구로 활용될 수 있을 것으로 판단된다.

Landsat 8/9 및 Sentinel-2 A/B를 이용한 울진 산불 피해 탐지: 다양한 지수를 기반으로 다시기 분석 (Forest Burned Area Detection Using Landsat 8/9 and Sentinel-2 A/B Imagery with Various Indices: A Case Study of Uljin)

  • 김병철;이경일;박선영;임정호
    • 대한원격탐사학회지
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    • 제38권5_2호
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    • pp.765-779
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    • 2022
  • 본 연구에서는 Landsat 8/9 OLI와 Sentinel-2 MSI 위성 영상을 활용한 다시기 영상 데이터를 이용하여 다양한 분광 지수를 기반으로 국내 산불 피해 면적 탐지 정확도를 분석하였다. 2022년 3월 경상북도 울진에서 발생하였던 산불을 대상으로 Difference Normalized Burn Ratio (dNBR), Relative Difference Normalized Burn Ratio (RdNBR), Burned Area Index (BAI) 등의 지수를 활용하여 산불피해 면적 탐지에 활용하였다. 비교적 높은 공간 해상도를 가진 Sentinel-2 영상을 기반으로 참조 자료를 제작하였다. 총 6개의 지수 산출물을 기반으로 Sentinel-2, Landsat 8/9으로 총 4개 위성에 대해 산불 피해 정확도를 각각 분석하였다. Landsat 8/9과 Sentinel-2는 각각 16일, 10일 주기로 영상을 제공하고 있지만 구름으로 인해 영상 취득에 어려움이 많은 편이며, 우리나라는 4월부터 식생의 생장이 시작되어 봄철 산불 피해 분석 시 산불발생 전후 영상을 활용하는 경우 식생의 생장으로 인한 변화가 커서 정확도 높은 탐지에 어려움이 있다. 따라서, 본 연구는 2월에서 5월까지의 다시기 Landsat 8/9과 Sentinel-2 영상 중 같은 날짜를 기반의 영상을 서로 사용하여 시간해상도의 한계를 극복하고 탐지 정확도가 상대적으로 높은 지수를 비교 분석했다. 본 연구 결과는 한국형 산불피해 탐지 지수/모델 개발을 위한 입력 자료 등으로 활용되어 최적화된 산불 지수를 기반으로 정확도 높은 산불 피해 면적 탐지에 활용될 수 있을 것으로 기대된다.

私設電子交換機SENTINEL -500에 대하여

  • 강진구;이주형
    • 전자공학회지
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    • 제5권1호
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    • pp.24-30
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    • 1978
  • 시분할다중화방식에 따른 전 전자소자에 의한 통화로 구성과 미니컴퓨터에 의한 축적프로그램 제어방식을 채용한 전전자식 사설전화교환기 SENTINEL-500을 소개 하였다. SENTINEL-500의 표준회선용양은 480가입자회선과 시내중단회선(국선) 100회선을 수용할 수 있으며 약 1500회선까지 확장가능토록 설계되었다. SENTINEL-500은 중요한 부분을 이중화하여 고신뢰도를 갖도록 하였고 다수하이웨이의 채용과 동적 Time Slot 배정방식을 개발하여 거의 완전한 Non-Blocking switchng network를 구성 하였다. 또한 SENTINEL-500은 자체진단기능을 위시 하여 교환중단대 및 가입자를 위한 각종의service 기능을 갖고 있다.

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Sentinel lymph node mapping using tri-modal human serum albumin conjugated with visible dye, near infrared fluorescent dye and radioisotope

  • Kang, Se Hun;Kim, Seo-il;Jung, So-Youn;Lee, Seeyoun;Kim, Seok Won;Kim, Seok-ki
    • 대한방사성의약품학회지
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    • 제1권1호
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    • pp.62-73
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    • 2015
  • We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer: Is It a Safe Procedure in Countries with Non-Endemic Gastric Cancer Levels? A Preliminary Experience

  • Neto, Guilherme Pinto Bravo;Santos, Elizabeth Gomes Dos;Victer, Felipe Carvalho;Neves, Marcelo Soares;Pinto, Marcia Ferreira;Carvalho, Carlos Eduardo De Souza
    • Journal of Gastric Cancer
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    • 제16권1호
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    • pp.14-20
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    • 2016
  • Purpose: Early diagnosis of gastric cancer is still the exception in Western countries. In the East, as in Japan and Korea, this disease is an endemic disorder. More conservative surgical procedures are frequently performed in early gastric cancer cases in these countries where sentinel lymph node navigation surgery is becoming a safe option for some patients. This study aims to evaluate preliminary outcomes of patients with early gastric cancer who underwent sentinel node navigation surgeries in Brazil, a country with non-endemic gastric cancer levels. Materials and Methods: From September 2008 to March 2014, 14 out of 205 gastric cancer patients underwent sentinel lymph node navigation surgeries, which were performed using intraoperative, endoscopic, and peritumoral injection of patent blue dye. Results: Antrectomies with Billroth I gastroduodenostomies were performed in seven patients with distal tumors. The other seven patients underwent wedge resections. Sentinel basin resections were performed in four patients, and lymphadenectomies were extended to stations 7, 8, and 9 in the other 10. Two patients received false-negative results from sentinel node biopsies, and one of those patients had micrometastasis. There was one postoperative death from liver failure in a cirrhotic patient. Another cirrhotic patient died after two years without recurrence of gastric cancer, also from liver failure. All other patients were followed-up for 13 to 79 months with no evidence of recurrence. Conclusions: Sentinel lymph node navigation surgery appears to be a safe procedure in a country with non-endemic levels of gastric cancer.

Current landscape and future perspective of sentinel node mapping in endometrial cancer

  • Bogani, Giorgio;Raspagliesi, Francesco;Maggiore, Umberto Leone Roberti;Mariani, Andrea
    • Journal of Gynecologic Oncology
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    • 제29권6호
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    • pp.94.1-94.10
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    • 2018
  • Endometrial cancer (EC) represents the most common gynecological neoplasm in developed countries. Surgery is the mainstay of treatment for EC. Although EC is characterized by a high prevalence several features regarding its management are still unclear. In particular the execution of lymphadenectomy is controversial. The recent introduction of sentinel node mapping represents the mid-way between the execution and omission of node dissection in EC patients. In the present review we discuss the emerging role of sentinel node mapping in EC. In addition, we discussed how type of tracers utilized and site of injection impacted on sentinel node detection rates. Future perspective regarding EC management are also discussed.