• Title/Summary/Keyword: Semi-health

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CDISC Transformer: a metadata-based transformation tool for clinical trial and research data into CDISC standards

  • Park, Yu-Rang;Kim, Hye-Hyeon;Seo, Hwa-Jeong;Kim, Ju-Han
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.5 no.10
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    • pp.1830-1840
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    • 2011
  • CDISC (Clinical Data Interchanging Standards Consortium) standards are to support the acquisition, exchange, submission and archival of clinical trial and research data. SDTM (Study Data Tabulation Model) for Case Report Forms (CRFs) was recommended for U.S. Food and Drug Administration (FDA) regulatory submissions since 2004. Although the SDTM Implementation Guide gives a standardized and predefined collection of submission metadata 'domains' containing extensive variable collections, transforming CRFs to SDTM files for FDA submission is still a very hard and time-consuming task. For addressing this issue, we developed metadata based SDTM mapping rules. Using these mapping rules, we also developed a semi-automatic tool, named CDISC Transformer, for transforming clinical trial data to CDISC standard compliant data. The performance of CDISC Transformer with or without MDR support was evaluated using CDISC blank CRF as the 'gold standard'. Both MDR and user inquiry-supported transformation substantially improved the accuracy of our transformation rules. CDISC Transformer will greatly reduce the workloads and enhance standardized data entry and integration for clinical trial and research in various healthcare domains.

A Study on Weaning Practice of Infants in Kangnung Area (강릉지역 영유아의 이유 실태에 관한 조사연구)

  • Kim, Eun-Kyung;Lee, Sun-Hee;Park, Kye-Wol;Chi, Kyung-A
    • Journal of the Korean Society of Food Culture
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    • v.14 no.5
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    • pp.555-563
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    • 1999
  • This study was executed for 300 mothers bringing up a child below 3 years in the area of Kangnung to assess the current weaning practice of infants. 24.6% of mother surveyed were breast-fed, 57.8% were formula-fed and 17.5% were mixed-fed. The rate of breast feeding was lower and the rate of bottle feeding was higher in infants whose mothers had more income or higher educational period or full-time job. Most of the respondents knew the significance of supplementary food. 41.4% of the subjects started weaning of their infants at 3-4 months, and 84.1% of them set on weaning in less than 7 months after babies were born. And 39.4% of the subjects finished weaning of their infants in less than one year. The infants of this study preferred the fruits and fishes to meats, vegetables and beans that served to them as supplementary food. Mothers showed deep interest in recipe of weaning food(48.5%), adequate quantity of weaning food(36.3%), information on commercial food for infants(32.2%), and sequence in which semi-solid food are introduced(31.9%). From these results, it is suggested that education program in primary health center for improvement of weaning practice of infants should be implemented reflecting needs of mothers.

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A Comparison of Different Depression Instruments for Stroke Patients (뇌졸중 환자의 우울증 평가도구 비교)

  • Lee, Dong-Jin;Shim, Jae-Kwang;An, Seung-Heon
    • The Journal of Korean Physical Therapy
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    • v.23 no.2
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    • pp.69-76
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    • 2011
  • Purpose: The aim of this study was to investigate the prevalence of depressive symptoms in stroke patients and to compare characteristics of different rating scales - Hamilton Depression Rating Scale (HDRS), Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale-Depression (HAD.D)- with regard to diagnosis and severity assessment for post-stroke depression. Methods: Participants included 44 stroke patients who could communicate. At admission, all study participants received a semi-structured interview using the HDRS and a self-completed questionnaire using the BDI and the HAD-D. Pearson's correlation method was used to examine associations among the three depression scales. The BDI and HAD-D were compared based on HDRS criteria, and the sensitivity and specificity using cut-off values were analyzed. Results: The HDRS showed that 52.30% of stroke patients had depressive symptoms on the BDI and HAD-D it was 59.10%. The HDRS correlated significantly with the BDI (r=0.81, p<0.01) and HAD-D (r=0.55, p<0.01). The BDI correlated significantly with HADS (r=0.50, p<0.01). After calculating the area under the ROC curve to decide on HDRS criteria, the BDI (AUC=0.91, 95% CI: 0.83.0.99) showed a significantly larger area compared to the HAD.D (AUC=0.82, 95% CI: 0.69-0.94). The cut-off value of the BDI was 12.50 points with a sensitivity of 81.00% and a specificity of 76.20%. Conclusion: These findings show that the BDI is a useful screening test for depression that most closely predicts the HRDS score.

Study on the Water Quality Control of Water Supply the Reside: Effects of Chlorinations (상수도의 수질관리와 타소소독의 잔류효과에 관한 연구)

  • 유귀현
    • Journal of environmental and Sanitary engineering
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    • v.6 no.2
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    • pp.33-47
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    • 1991
  • 1. Water supply treatment plants personnel could not test the water quality control, because most of them rely on the provincial health laboratories about water quality rely rant test. However, in future, plants have to been provided the facilities and equipment of water quality laboratory. 2. Chlorination methods are 89.5% of liquid chlorine and 10.5% of solid chlorine, and the cost per 1 $\m^{3}$ of chlorination is about 1.30 won which chlorination cost is very cheap as 1/142 of drinking water production cost. Input method of chlorine is 35% of automatic method, 56% of semi-automatic, and 9% of other methods, and this is no problem 3. Residual effects of chlorination, in the case of distilled water as a standardized material and 0.2 ppm of seperated residual chlorine, were continued 32 hours in $0^{\circ}C$, and 25 hour in $20^{\circ}C$, of water temperature and in the case of 0.4 ppm of seperated residual chlorine were continued 47 hours in $0^{\circ}C$ and 23 hours in $20^{\circ}C$. 4. In the case of 4 ppm of seperated residual chlorine, residual effects were continued 23 hours in $5^{\circ}C$, 90 hours in $10^{\circ}C$, 78 hours in $15^{\circ}C$, and 60 hours in $20^{\circ}C$ : by the temper; lure of water, continuing residual effects of chlorination are different, so we have to car for the warm season chlorination in the hider temperature. 5. Chlorination effects of drinking waters in the case of 0.4 ppm of seperated residual chlorine were continued 237 hours in $22^{\circ}C$ water : and in the case of rechlorination as 4 ppm of residual chlorine, continued 71 hours in $22^{\circ}C$ water.

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The cultivation of wild food and medicinal plants for improving community livelihood: The case of the Buhozi site, DR Congo

  • Karhagomba, Innocent Balagizi;Adhama, Mirindi T.;Mushagalusa, Timothee B.;Nabino, Victor B.;Koh, Kwangoh;Kim, Hee Seon
    • Nutrition Research and Practice
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    • v.7 no.6
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    • pp.510-518
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    • 2013
  • This study aims to demonstrate the effect of farming technology on introducing medicinal plants (MP) and wild food plants (WFP) into a traditional agricultural system within peri-urban zones. Field investigations and semi-structured focus group interviews conducted in the Buhozi community showed that 27 health and nutrition problems dominated in the community, and could be treated with 86 domestic plant species. The selected domestic MP and WFP species were collected in the broad neighboring areas of the Buhozi site, and introduced to the experimental field of beans and maize crops in Buhozi. Among the 86 plants introduced, 37 species are confirmed as having both medicinal and nutritional properties, 47 species with medicinal, and 2 species with nutritional properties. The field is arranged in a way that living hedges made from Tithonia diversifolia provide bio-fertilizers to the plants growing along the hedges. The harvest of farming crops does not disturb the MP or WFP, and vice-versa. After harvesting the integrated plants, the community could gain about 40 times higher income, than from harvesting farming crops only. This kind of field may be used throughout the year, to provide both natural medicines and foods. It may therefore contribute to increasing small-scale crop producers' livelihood, while promoting biodiversity conservation. This model needs to be deeply documented, for further pharmaceutical and nutritional use.

A Study on the Establishment and Management of a Library for Older Adults (노인도서관 설립과 운영에 관한 연구)

  • Lim, Seong-Kwan
    • Journal of the Korean Society for Library and Information Science
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    • v.54 no.2
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    • pp.323-348
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    • 2020
  • The purpose of this study is to suggest a plan to establishment and management for a library for old adults. Therefore, the library for old adults defined to the concept of providing a specialized service by providing the necessary material with an elderly user over 65 focus. And presenting the basic direction and specific direction, organizational plan, and ordinance on establishment and management of a library for older adults. In addition, after conducting a semi-structured interview based on a pre-prepared questionnaire targeting 30 elderly people aged 65 or older who had experiences using public libraries, the results were analyzed, and 20 responses indicated that the purpose of using the library was a way to participate in the program as an essential service for the elderly. 12 respondents stated that the purpose of using the library was possibly a necessity for such things as writing autobiographies and reflections of historical events. Lastly, investigating the operational cases of two public libraries that already utilize elderly learning and health information rooms, it was concluded that the operation of the elderly library also needs to reflect the regional differences and characteristics unique to older adults.

Asymptomatic Human Paragonimiasis among the Karen People in Tak Province, Thailand: A Case Report

  • Kusolsuk, Teera;Phuphisut, Orawan;Maipanich, Wanna;Pubampen, Somchit;Sa-nguankiat, Surapol;Poodeepiyasawat, Akkarin;Homsuwan, Nirundorn;Mongkolmoo, Srisuchart;Yoonuan, Tippayarat;Adisakwattana, Poom;Silachamroon, Udomsak;Nawa, Yukifumi
    • Parasites, Hosts and Diseases
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    • v.58 no.1
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    • pp.57-60
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    • 2020
  • During the mobile clinic activities in Tak Province, Thailand, Paragonimus sp. eggs were found in a fecal sample of a 72-year-old Karen resident. Paragonimus DNA was amplified from the stool sample and identified to P. heterotremus. The patient did not have any symptoms. Apparent pulmonary lesion was not found on the chest X-ray. The patient admitted habitual consumption of semi-cooked or roasted waterfall crabs for several years. The waterfall crabs collected from stream near the village were found negative for Paragonimus metacercariae. In northern Thailand, paragonimiasis remains as one of the public health concerns and should be ruled out for asymptomatic pulmonary patients.

Body Composition, Food Intake and Clinical Blood Indices of Female College Students (일부 여대생의 체성분, 식이 섭취실태 및 혈액 임상조사)

  • 김정희;안혜준;이상은
    • Korean Journal of Community Nutrition
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    • v.8 no.6
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    • pp.977-985
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    • 2003
  • This study was done to evaluate the health and nutritional status of female college students in Seoul. The subjects were 63 healthy college students aged 20 to 29 years. Their body composition, dietary intakes, clinical blood indices were investigated. Their body composition was determined by means of a multifreqency bioelectrical impedance analysis. Their dietary intake was determined using 3-day record method and their nutrient intake was analyzed by Computer Aided Nutritional analysis program for professional (CAN-pro). Their hemoglobin, hematocrit, red blood cell (RBC), white blood cell (WBC) and mean corpuscular volume (MCV) were determined by semi-automated microcell counter (F-520). Their plasma total cholesterol, TG, and HDL-cholesterol levels were measured using test kits. All data were statistically analyzed by SAS PC package program. Their average consumption of calcium, iron vitamin A, vitamin B2 and niacin were 63.3%, 65.0%, 85.2%, 89.2% and 95.2% of RDA, respectively. The overall mean values of the hematological indices in the female college students were within the normal range. However anemic subjects with hemoglobin (< 12 g/dl) and hematocrit (<36%) accounted for about 20% of the subjects. The mean levels of total cholesterol, HDL-cholesterol and TG were 188.4mg/dl, 69.9mg/dl and 67.4mg/dl, respectively. The percentages of the subjects with plasma total cholesterol level (> 200mg/dl) and LDL-cholesterol (>130mg/dl) were about 41% and 30.4%, respectively. The data showed a significantly positive correlation between either body fat (%) or BMI and TG. However. there was a significantly negative correlation between either body fat (%) or BMI and HDL-cholesterol. These overall results suggest that it is necessary for college women to be educated regarding consuming more iron and vitamin C and less fat, in order to prevent iron deficiency anemia and/or cardiovascular diseases in later life.

Ultrasonic guided wave approach incorporating SAFE for detecting wire breakage in bridge cable

  • Zhang, Pengfei;Tang, Zhifeng;Duan, Yuanfeng;Yun, Chung Bang;Lv, Fuzai
    • Smart Structures and Systems
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    • v.22 no.4
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    • pp.481-493
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    • 2018
  • Ultrasonic guided waves have attracted increasing attention for non-destructive testing (NDT) and structural health monitoring (SHM) of bridge cables. They offer advantages like single measurement, wide coverage of acoustical field, and long-range propagation capability. To design defect detection systems, it is essential to understand how guided waves propagate in cables and how to select the optimal excitation frequency and mode. However, certain cable characteristics such as multiple wires, anchorage, and polyethylene (PE) sheath increase the complexity in analyzing the guided wave propagation. In this study, guided wave modes for multi-wire bridge cables are identified by using a semi-analytical finite element (SAFE) technique to obtain relevant dispersion curves. Numerical results indicated that the number of guided wave modes increases, the length of the flat region with a low frequency of L(0,1) mode becomes shorter, and the cutoff frequency for high order longitudinal wave modes becomes lower, as the number of steel wires in a cable increases. These findings were used in design of transducers for defect detection and selection of the optimal wave mode and frequency for subsequent experiments. A magnetostrictive transducer system was used to excite and detect the guided waves. The applicability of the proposed approach for detecting and locating wire breakages was demonstrated for a cable with 37 wires. The present ultrasonic guided wave method has been found to be very responsive to the number of brokenwires and is thus capable of detecting defects with varying sizes.

GPS/RTS data fusion to overcome signal deficiencies in certain bridge dynamic monitoring projects

  • Moschas, Fanis;Psimoulis, Panos A.;Stiros, Stathis C.
    • Smart Structures and Systems
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    • v.12 no.3_4
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    • pp.251-269
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    • 2013
  • Measurement of deflections of certain bridges is usually hampered by corruption of the GPS signal by multipath associated with passing vehicles, resulting to unrealistically large apparent displacements. Field data from the Gorgopotamos train bridge in Greece and systematic experiments revealed that such bias is due to superimposition of two major effects, (i) changes in the geometry of satellites because of partial masking of certain satellites by the passing vehicles (this effect can be faced with solutions excluding satellites that get temporarily blocked by passing vehicles) and (ii) dynamic multipath caused from reflection of satellite signals on the passing trains, a high frequency multipath effect, different from the static multipath. Dynamic multipath seems to have rather irregular amplitude, depending on the geometry of measured satellites, but a typical pattern, mainly consisting of a baseline offset, wide base peaks correlating with the sequence of main reflective surfaces of the vehicles passing next to the antenna. In cases of limited corruption of GPS signal by dynamic multipath, corresponding to scale distortion of the short-period component of the GPS waveforms, we propose an algorithm which permits to reconstruct the waveform of bridge deflections using a weak fusion of GPS and RTS data, based on the complementary characteristics of the two instruments. By application of the proposed algorithm we managed to extract semi-static and dynamic displacements and oscillation frequencies of a historical railway bridge under train loading by using noisy GPS and RTS recordings. The combination of GPS and RTS is possible because these two sensors can be fully collocated and have complementary characteristics, with RTS and GPS focusing on the long- and short-period characteristics of the displacement, respectively.