• Title/Summary/Keyword: Semi-health

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Genotoxicity of Heavy Metals among the Particulates in the Working Environment as Assessed by Tradescantia-Micronucleus (Trad-MCN) Assay (자주달개비 미세핵 분석법을 이용한 작업환경내 총 먼지 중 수용성 추출물의 유전독성 평가)

  • Shin, Hae-Shik;Kim, Jin-Kyu;Lee, Jae-Hwan;Hwang, Kap-Sung;Kim, Kyun;Lee, Jeong-Joo;Lee, Jin-Hong
    • Journal of Korean Society for Atmospheric Environment
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    • v.19 no.6
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    • pp.639-646
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    • 2003
  • In this study, we evaluated genotoxicity of heavy metals among particulates with Tradescantia-micronucleus (Trad-MCN) assay in the various working environment. In a synthetic fiber factory and a rubber factory, chromium concentration was higher than any other heavy metals. On the other hand, nickel concentration was the highest in a semi-conductor factory. The difference in genotoxicity among the working environment was statistically significant as Trad-MCN frequencies were 4.07 $\pm$0.35 MCN/100 tetrads (p< 0.01) for the synthetic fiber factory,5.73 $\pm$0.81 MCN/100 tetrads (p< 0.01) for the rubber factory, and 15.60$\pm$2.58 (p< 0.01) (p< 0.001) for the semi -conductor factory. As a result, heavy metals among particulates in the working environment can be considered to have hazardous potential to human health, although they cannot directly induce DNA damage to the workers in the working environments.

Relative validities of 3-day food records and the food frequency questionnaire

  • Yang, Yoon-Jung;Kim, Mi-Kyung;Hwang, Se-Hee;Ahn, Youn-Jhin;Shim, Jae-Eun;Kim, Dong-Hyun
    • Nutrition Research and Practice
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    • v.4 no.2
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    • pp.142-148
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    • 2010
  • The food frequency questionnaire (FFQ) has been used as an important dietary assessment tool in epidemiologic studies, but the usefulness of the FFQ has been debated in recent years. This study was performed to evaluate the relative validities of 3-day food records and the semi-quantitative FFQ. A total of 124 subjects finished 3-day food records (FRs) during each of the four seasons, as well as the FFQ from December 2002 to May 2004. The FFQ was a food based semi-quantitative FFQ including 103 items. Three-day FRs from each season and a randomly selected season were compared with the remaining 9-day FRs. The remaining 9-day FRs, as a reference measurement, were also compared with the FFQ. Pearson's correlation coefficients between the 3-day FRs and the 9-day FRs were between 0.14 and 0.56. Pearson's correlation coefficients between the FFQ and the 9-day FRs ranged between 0.07 and 0.41. Average proportions of classification into the same quartiles, adjacent quartiles, and distant quartiles between the 3-day FRs and the 9-day FRs were 35.8%, 40.5%, and 5.2%, respectively. On average, the proportions of classification into the same quartiles, adjacent quartiles, and distant quartiles between the FFQ and the 9-day FRs were 31.1%, 39.4%, and 6.9%, respectively. Three-day FRs showed higher correlations and higher agreement proportions of quartile classification with the 9-day FRs than did the FFQ, but both relative validities of 3-day FRs and the FFQ appear to be acceptable as dietary assessment tools. Further studies for validating food intake by reliable biomarkers are necessary.

Comparison of the Corneal Topography Changes as a Result of Near Task between Myopes and Emmetropes (근시와 정시 사이에서 근거리 작업의 결과로서 각막 지도 변화와 비교)

  • Chen, A.H.;Othman, R.;Kim, D.H.
    • Journal of Korean Ophthalmic Optics Society
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    • v.8 no.1
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    • pp.11-15
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    • 2003
  • Purpose : The purpose of this study is to investigate the corneal topography changes as a result of near task in myopes and emmetropes. Methods : Thirty university students, aged from 18 to 24 years old, were randomly selected. They were divided into two refractive groups of fifteen each : myopia and emmetropia. The corneal topography of each subject was measured with the Eye-Sys Videokeratography system. Measurements were taken : before and after 30 minutes of near task (copy N10 text at 20 cm working distance). Both simulated keratometry and semi-meridian keratometric map program were used in the data analysis. Results : Our results reveal no significant changes in both simulated keratometry and semi-meridian presentation as a result of near task for both myopes and emmetropes, except a significant change (p<0.05) found at the flattest meridian of the central (3 mm) portion of the corneal topography after near task for emmetropes only. Conclusions : We conclude that the corneal topography, does not change significantly as a result of near task in both myopes and emmetropes.

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Weaning Practice for Infants in Daejeon City (영유아의 이유실태(離乳實態) -대전지역(大田地域)-)

  • Chung, Young-Jin
    • Journal of Nutrition and Health
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    • v.12 no.1
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    • pp.23-30
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    • 1979
  • For the purpose of investigating the weaning practice for infants, this study of 251 infants aged from 3 months to 2 years old was conducted in Daejeon City during the the period of August 9 through 23, 1978. The results obtained were as follows: About 60% of the infants were breast-fed, 27.6%, mixed-fed, and 12.0%, bottled-fed. The reason for bottle-feeding was either the lack of breast-milk secretion or ill-health of mothers. There was no significant difference in the feeding methods according to a level of mother's education. Sixty precent of the infants began to be weaned 6. months. The most of the infants were completely weaned within 18 months. The knowledge on weaning was mainly obtained from the publications, such as newspapers, journals for women, child care booklets, etc. The difficulties in the weaning practice were the shortage of knowledge on weaning and the unacceptability by the infants. Liquid or semi-liquid foods were firstly given to the more than 60% of the infants as introducing weaning foods, while 23.3% of the babies were given solid foods. Interestingly, the earlier the birth order was, the more babies were given liquid or semi-liquid foods, The motives for weaning was either the boby's demand for other foods than milk(41.3%) or the lack of breast-milk secretion (31.3%). In the selection of supplementary foods, the nutritional value was given the highest consideration) (54.9%). many mothers (64.2%) prepared supplementary foods for infants at home, while 23.1% used commercial body foods and 12.7% gave infants adult's meals as supplementary foods. The major materials for home-made supplementary foods were fruits and vegetables (41.5%) and cereals (37.5%). The commercial supplementary foods (mainly powdered from) were not used much (never used; 53.6%) and even in the babies, who had consumed them once, nearly half of the babies (42.9) did not eat well. Accordingly, the many mothers (68.8%) welcomed the development of the domestic supplementary foods in good quality and one-third (31.2%) responded that they would consume them regardless of the price.

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Oleuropein Induces Apoptosis Via the p53 Pathway in Breast Cancer Cells

  • Hassan, Zeinab Korany;Elamin, Maha Hussein;Omer, Sawsan Ali;Daghestani, Maha Hassan;Al-Olayan, Ebtesam Salah;Elobeid, Mai AbdelRahman;Virk, Promy
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6739-6742
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    • 2013
  • Background: Breast cancer is a major health problem worldwide. Olive oil induces apoptosis in some cancer cells due to phenolic compounds like oleuropein. Although oleuropein has anticancer activity, the underlying mechanisms of action remain unknown. The study aimed to assess the mechanism of oleuropin-induced breast cancer cell apoptosis. Materials and Methods: p53, Bcl-2 and Bax gene expression was evaluated by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in luminal MCF-7 cells. Results: Oleuropein-induced apoptosis was accompanied by up-regulation of both p53 and Bax gene expression levels and down-regulation in Bcl2. Conclusions: Oleuropein induces apoptosis in breast tumour cells via a p53-dependent pathway mediated by Bax and Bcl2 genes. Therefore, oleuropein may have therapeutic potential in breast cancer patients by inducing apoptosis via activation of the p53 pathway.

Characteristics of Environment-friendly Semi-dry Turning (환경 친화적인 세미드라이 선삭가공 특성)

  • Lee, Jong-Hang;Lee, Sang-Jo;Lee, Seok-U;Choe, Heon-Jong
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.10
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    • pp.221-226
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    • 2002
  • As environmental restriction has continuously become more strict, machining technology has emphasized on development of environment-friendly technologies. In cutting technology, it has been well recognized that cutting fluids might have undesirable effects on workers health and working environment and, hence, recently there have been numerous attempts to minimize harmful effects of cutting fluids on environments. To minimize the use of cutting fluids in machining, conventional cutting fluids have been replaced with the technologies of pressurized cold air and minimum quantity lubrication (MQL). Compared with milling, turning is continuous cutting process, where tools are continuously heated up and lack of lubricity could lead to tool wear and deteriorated surface roughness. In this work, it has been investigated how tool wear and surface roughness could be affected by cutting conditions, supply and cooling methods. The experimental results show that MQL technology is able to minimize conventional cutting fluids.

Particle Scavenging Properties of Rain Clarified by a Complementary Study with Bulk and Semi-bulk Samples

  • Ma, Chang-Jin;Kang, Gong-Unn
    • Journal of Korean Society for Atmospheric Environment
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    • v.34 no.1
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    • pp.177-186
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    • 2018
  • It is a well-known fact that precipitation plays an important role in capturing ambient particles, however, the details of particle scavenging properties have not been fully proved. To clarify the particle scavenging properties, a complementary study was carried out with the bulk and semi-bulk rain samples collected in an urban city of Japan. pH showed a continued downturn for a little bit at the beginning rainfall and then a turn-up in the following rainfall. The recorded pH values of rainwater (ranged from 3.5-4.6) demonstrated that the strong acid rain was observed during our field measurements. Compared to the subsequent rainfall, electrical conductivity in the beginning rainfall had about 1.3 times higher level. Sulfur showed an overwhelmingly high concentration compared to other elements in both ambient total suspended particles (TSP) and rain samples. On the contrary to ambient TSP, every element including Ca and Zn in rain showed a continued rise in concentration accompanied by increasing of rainfall amount. During the first period of the rainfall there was no meaningful change in elemental carbon concentration, however, it was largely increased (up to $0.2mg\;L^{-1}$) in the sequential rainfall (4.0-4.5 mm rainfall amount). The theoretically calculated number concentration of particles scavenged by raindrops showed a strong decrease of with the increasing droplet diameter regardless of particle type.

A preliminary study of semi-quantitative, comparative evaluation of split or half fingerprints using Densitometric Image Analysis (DIA) - Inter-analyst differences for split or half fingerprints -

  • Song, Minkyu;Kim, Seung-chan;Choi, Sung-Woon
    • Analytical Science and Technology
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    • v.34 no.2
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    • pp.56-67
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    • 2021
  • Due to the difficulty of grading visualized fingerprints with previously known evaluation methods for the comparison of split fingerprints, a preliminary study was performed with the densitometric image analysis (DIA) method as a potential quantitative and supplementary evaluation method. Each image of inked split fingerprints was divided into 4 zones for analysis. Weekly intra- and inter- analysis by two analysts with three whole fingerprints that were constructed by combining inked split fingerprints showed that the average area values and the ranges of difference fluctuation were not significantly different between strong fingerprints and strong-weak pairs, while they were different in weak fingerprints and weak-weak pairs. In the case of weak fingerprints, the exact acquisition of ridges was difficult and this seemed to influence the results. An additional study is needed for the improved reliability using DIA method with weak fingerprints such as 8 zones division rather than 4 zones. In addition, the analysis results performed by several analysts at different times should be used to improve the reliability of the analysis method further. Based on the above result, it can be judged that utilizing the DIA method as a secondary evaluation method of the existing scoring system would be effective with the additional studies especially on weak fingerprints.

A Study on Public Nuisance in Seoul, Pusan and Daegu Cities Part I. Survey on Air Pollution and Noise Level (공해(公害)에 관(關)한 조사연구(調査硏究) 제일편(第一編) : 서울, 부산(釜山), 대구(大邱) 지역(地域)의 대기오염(大氣汚染) 및 소음(騷音)에 관(關)한 비교조사(比較調査) 연구(硏究))

  • Cha, Chul-Hwan;Shin, Young-Soo;Lee, Young-Il;Cho, Kwang-Soo;Choo, Chong-Yoo;Kim, Kyo-Sung;Choi, Dug-Il
    • Journal of Preventive Medicine and Public Health
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    • v.4 no.1
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    • pp.41-64
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    • 1971
  • During the period from July 1st to the end of November 1970, a survey on air pollution and noise level was made in Seoul, Pusan and Taegu, the three largest cities in Korea. Each city was divided into 4-6 areas; the industrial area, the semi-industrial area, the commercial area, the residential area, the park area and the downtown area. Thirty eight sites were selected from each area. A. Method of Measurement : Dustfall was measured by the Deposit Gauge Method, sulfur oxides by $PbO_2$ cylinder method, suspended particles by the Digital Dust Indicator, Sulfur dioxide ($SO_2$) and Carbon Monoxide (CO) by the MSA & Kitakawa Detector and the noise levels by Rion Sound Survey meter. B. Results: 1. The mean value of dustfall in 3 cities was $30.42ton/km^2/month$, ranging from 8.69 to 95.44. 2. The mean values of dustfall by city were $33.17ton/km^2/month$ in Seoul, 32.11 in Pusan and 25.97 in Taegu. 3. The mean values of dustfall showed a trend of decreasing order of semi-industrial area, downtown area, industrial area, commercial area, residential area, and park area. 4. The mean value of dustfall in Seoul by area were $52.32ton/km^2/month$ in downtown, 50.54 in semi-industrial area, 40.37 in industrial area, 24,19 in commercial area, 16.25 in park area and 15.39 in residential area in order of concentration. 5. The mean values of dustfall in Pusan by area were $48.27ton/km^2/month$ in semi-industrial area, 36.68 in industrial area 25.31 in commercial area, and 18.19 in residential area. 6. The mean values of dustfall in Taegu by area were $36.46ton/km^2/month$ in downtown area, 33.52 in industrial area, 20.37 in commercial area and 13.55 in residential area. 7. The mean values of sulfur oxides in 3 cities were $1.52mg\;SO_3/day/100cm^2\;PbO_2$, ranging from 0.32 to 4.72. 8. The mean values of sulfur oxides by city were $1.89mg\;SO_3/day/100cm^2\;PbO_2$ in Pusan, 1.64 in Seoul and 1.21 in Taegu. 9. The mean values of sulfur oxides by area in 3 cities were $2.16mg\;SO_3/day/100cm^2\;PbO_2$ in industrial area, 1.69 in semi-industrial area, 1.50 in commercial area, 1.48 in downtown area, 1.32 in residential area and 0.94 in the park area, respectively. 10. The monthly mean values of sulfur oxides contents showed a steady increase from July reaching a peak in November. 11. The mean values of suspended particles was $2.89mg/m^3$, ranging from 1.15 to 5.27. 12. The mean values of suspended particles by city were $3.14mg/m^3$ in Seoul, 2.79 in Taegu and 2.25 in Pusan. 13. The mean values of noise level in 3 cities was 71.3 phon, ranging from 49 to 99 phon. 14. The mean values of noise level by city were 73 phon in Seoul, 72 in Pusan, and 69 in Taegu in that order. 15. The mean values of noise level by area in 3 cities showed a decrease in the order of the downtown area, commercial area, industrial area and semi-industrial area, park area and residential area. 16. The comparison of the noise levels by area in 3 cities indicated that the highest level was detected in the downtown area in Seoul and Taegu and in the industrial area in Pusan. 17. The daily average concentration of sulfur dioxides ($SO_2$) in 3 cities was 0.081 ppm, ranging from 0.004 to 0.196. 18. The daily average concentrations of sulfur dioxides by city were 0.092 ppm in Seoul, 0.089 in Pusan and 0.062 in Taegu in that order. 19. The weekly average concentration of carbon monoxides(CO) was 27.59 ppm. 20. The daily average concentrations of carbon monoxides by city were 33.37 ppm. in Seoul, 25.76 in Pusan and 23.65 in Taegu in that order. 21. The concentration of $SO_2$ and CO reaches a peak from 6 p. m. to 8 p. m. 22. About 3 times probably the daily average concentration of CO could be detected in the downtown area probably due to heavy traffic emission in comparison with that in the industial area. 23. As for daily variation of the concentration of $SO_2$ and CO it was found that the concentration maintains relatively higher value during weekdays in the industrial area and on the first part of the week in the downtown area.

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Nurses' Experiences of Caring for Disabled Women during Pregnancy and Childbirth (여성장애인을 위한 임신과 출산 돌봄에 대한 간호사의 경험)

  • Lee, Eun-Joo
    • Women's Health Nursing
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    • v.22 no.4
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    • pp.308-321
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    • 2016
  • Purpose:This phenomenological study was to describe and to understand nurses' experiences of caring for woman with disability during pregnancy and childbirth. Methods: Participants were 13 nurses from 3 hospitals and 2 local clinics in J city, and were selected through snow-balling method. Data were collected two face to face, semi-structured interviews. The researcher used MP3 player and smart phone for recording as well as transcription process. As for the data analysis, Colaizzi's method was applied. Results: Nurses' experiences were structured as four theme clusters: 'Communicating between/among nurses', 'Recognizing pregnancy and childbirth of woman with disability', 'Taking care of woman with disability based on their differences' and 'Reflecting on nursing care for woman with disability'. Conclusion: It seemed that nurses' recognition to woman with disability and her pregnancy and childbirth was related their nursing care for woman with disability.