• Korean Journal of Radiology
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• 제22권11호
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• pp.1797-1808
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• 2021

Objective: To determine whether volumetric CT texture analysis (CTTA) using fully automatic tumor segmentation can help predict recurrence-free survival (RFS) in patients with intrahepatic mass-forming cholangiocarcinomas (IMCCs) after surgical resection. Materials and Methods: This retrospective study analyzed the preoperative CT scans of 89 patients with IMCCs (64 male; 25 female; mean age, 62.1 years; range, 38-78 years) who underwent surgical resection between January 2005 and December 2016. Volumetric CTTA of IMCCs was performed in late arterial phase images using both fully automatic and semi-automatic liver tumor segmentation techniques. The time spent on segmentation and texture analysis was compared, and the first-order and second-order texture parameters and shape features were extracted. The reliability of CTTA parameters between the techniques was evaluated using intraclass correlation coefficients (ICCs). Intra- and interobserver reproducibility of volumetric CTTAs were also obtained using ICCs. Cox proportional hazard regression were used to predict RFS using CTTA parameters and clinicopathological parameters. Results: The time spent on fully automatic tumor segmentation and CTTA was significantly shorter than that for semi-automatic segmentation: mean ± standard deviation of 1 minutes 37 seconds ± 50 seconds vs. 10 minutes 48 seconds ± 13 minutes 44 seconds (p < 0.001). ICCs of the texture features between the two techniques ranged from 0.215 to 0.980. ICCs for the intraobserver and interobserver reproducibility using fully automatic segmentation were 0.601-0.997 and 0.177-0.984, respectively. Multivariable analysis identified lower first-order mean (hazard ratio [HR], 0.982; p = 0.010), larger pathologic tumor size (HR, 1.171; p < 0.001), and positive lymph node involvement (HR, 2.193; p = 0.014) as significant parameters for shorter RFS using fully automatic segmentation. Conclusion: Volumetric CTTA parameters obtained using fully automatic segmentation could be utilized as prognostic markers in patients with IMCC, with comparable reproducibility in significantly less time compared with semi-automatic segmentation.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1999년도 하계종합학술대회 논문집
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• pp.619-622
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• 1999

This paper describes a new semi-automatic segmentation algorithm based on color information. Semi-automatic segmentation mainly consists of intra-frame segmentation and inter-frame segmentation. While intra-frame segmentation extracts video objects of interest from boundary information provided by the user and intensity information of the image, inter-frame segmentation partitions the image into the video objects and background by tracking the motion of video objects. For inter-frame segmentation, color information (Y, Cb and Cr) of the current frame can be used efficiently in order to find the exact boundary of the video objects. In this paper we propose a new region growing algorithm which can maximize the ability of region differentiation, while preserving features of each color component.

• 대한의용생체공학회:의공학회지
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• 제30권2호
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• pp.153-161
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• 2009

Mammogram is one of the important techniques for mass detection, which is the early diagnosis stage of a breast cancer. Especially, the CAD(Computer Aided Diagnosis) using mammogram improves the working performance of radiologists as it offers an effective mass detection. There are two types of CAD systems using mammogram; automatic and semi-automatic CAD systems. However, the automatic segmentation is limited in performance due to the difficulty of obtaining an accurate segmentation since mass occurs in the dense areas of the breast tissue and has smoother boundaries. Semi-automatic CAD systems overcome these limitations, however, they also have problems including high FP (False Positive) rate and a large amount of training data required for training a classifier. The proposed system which overcomes the aforementioned problems to detect mass is composed of the suspected area selection, the level set segmentation and SVM (Support Vector Machine) classification. To assess the efficacy of the system, 60 test images from the FFDM (Full-Field Digital Mammography) are analyzed and compared with the previous semi-automatic system, which uses the ANN classifier. The experimental results of the proposed system indicate higher accuracy of detecting mass in comparison to the previous systems.

• 한국멀티미디어학회논문지
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• 제9권5호
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• pp.529-541
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• 2006

본 논문에서는 객체기반 비디오 부호화 또는 멀티미디어 편집을 위한 반지동 비디오 객체 분할방식을 제안한다. 반자동 객체분할은 사용자 지원에 의한 분할 방식으로, 비디오 시퀀스의 초기 프레임에서 사용자가 관심객체의 경계를 표시하고 이후의 영상 프레임의 객체를 배경으로부터 연속적으로 분리해 낸다. 제안된 방식은 부분적으로 사용자 조력에 의한 프레임내 분할과 완전 자동에 의한 프레임간 분할 처리과정으로 구성되는데, 영상 전체에 대해 연산을 수행하는 기존 방식과는 달리 객체 경계가 존재하는 영상영역 부분에서만 연산을 수행한다. 프레임내 분할은 사용자가 관심객체의 경계를 지정하고, 이 경계 주위 화소들의 유사성을 이용한 후처리에 의해 정확한 초기 객체를 구한다. 프레임간 분할에서는 이전 프레임에서 추출한 객체의 경계 정보에 근거하여 시간적 유사성을 구한 후 경계와 영역 추적에 의해 연속적으로 동영상 객체를 추출한다. 실험결과로부터 제안된 방식은 비디오 편집, 객체기반 비디오 압축 및 인덱싱 등의 멀미디어 응용에 사용 가능할 정도로 안정되고 정확한 객체추출을 수행함을 확인하였다. 이 결과를 바탕으로 다수의 편리한 기능을 포함한 비디오 편집시스템을 개발하였다.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2009년도 IWAIT
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• pp.55-58
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• 2009

Automatic segmentation of brain MRI data usually leaves some segmentation errors behind that are to be subsequently removed interactively, using computer graphics tools. This interactive removal is normally performed by operating on individual 2D slices. It is very tedious and still leaves some segmentation errors which are not visible on the slices. We have proposed to perform a novel 3D interactive correction of brain segmentation errors introduced by the fully automatic segmentation algorithms. We have developed the tool which is based on 3D semi-automatic propagation algorithm. The paper describes the implementation principles of the proposed tool and illustrates its application.

• 한국컴퓨터정보학회논문지
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• 제11권4호
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• pp.283-289
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• 2006

현재 영상분할은 사용자가 원하는 영상을 분할하고, 분할된 객체에 다른 영상을 합성하는 기술에 대해 많은 연구가 진행되어왔다. 본 논문에서는 점진적 영역병합과 유전자 알고리즘을 이용하여 새로운 반자동 영상 분할방법을 제안하였다. 제안된 알고리즘은 사용자가 원하는 객체를 선정한 후, 유전자 알고리즘을 이용해 객체의 경계를 검색한다. 검색된 경계를 기반으로 분수령 알고리즘을 이용하여 사용자가 원하는 객체의 영역을 분할하였다. 분할된 객체에서 불명확한 영역들을 점진적 영역 병합으로 배경과 객체를 분리하였다. 그리고, 알고리즘 개발을 효과적으로 수행하기 위해 GUI기반의 인터페이스를 만들어 사용자가 원하는 값을 적용할 수 있게 하였다. 실험에서는 제한된 방법의 우수성 입증을 위하여 다양한 영상을 분석하였다.

• International Journal of Contents
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• 제9권1호
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• pp.6-10
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• 2013

Foreground estimation in object segmentation has been an important issue for last few decades. In this paper we propose a GrabCut based automatic foreground estimation method using block clustering. GrabCut is one of popular algorithms for image segmentation in 2D image. However GrabCut is semi-automatic algorithm. So it requires the user input a rough boundary for foreground and background. Typically, the user draws a rectangle around the object of interest manually. The goal of proposed method is to generate an initial rectangle automatically. In order to create initial rectangle, we use Gabor filter and Saliency map and then we use 4 features (amount of area, variance, amount of class with boundary area, amount of class with saliency map) to categorize foreground and background. From the experimental results, our proposed algorithm can achieve satisfactory accuracy in object segmentation without any prior information by the user.

• 대한의용생체공학회:의공학회지
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• 제26권6호
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• pp.407-412
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• 2005

Convenience is one of the most important factors in medical image segmentation. Convenience is defined by compiling opinions from radiologists, and can be described as controllable maximum automation on the condition of producing only accurate results. The components of convenience are inclusive automation and inclusive modification. Inclusive modification consists of verify-and-confirm, undo-redo, exchange of segmentation methods, and intelligent modification tools. Inclusive automation is composed of automatic selection of a method, automatic selection of a confident segment, and automated chores. The convenient segmentation tool has been developed to segment X-ray images for orthopedic surgery, and has received an excellent evaluation from radiologists.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.791-797
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• 2007

This paper proposes a semiautomatic vertebra segmentation method that overcomes limitations of both manual segmentation requiring tedious user interactions and fully automatic segmentation that is sensitive to initial conditions. The proposed method extracts fence surfaces between vertebrae, and segments a vertebra using fence-limited region growing. A fence surface is generated by a deformable model utilizing valley information in a valley emphasized Gaussian image. Fence-limited region growing segments a vertebra using gray value homogeneity and fence surfaces acting as barriers. The proposed method has been applied to ten patient data sets, and produced promising results accurately and efficiently with minimal user interaction.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제16권11호
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• pp.1096-1100
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• 2010

본 논문에서는 MR 영상에서 중간형상정보를 이용한 활성형상모델 기반의 반월상 연골 자동 분할 기법을 제안한다. 첫째, 훈련집합 내의 형상 변형을 반영하기 위해 반월상 연골 통계형상모델을 생성한다. 둘째, 큰 변형을 갖는 반월상 연골의 견고한 분할을 위해 유사도에 따른 가중치 기법을 이용하여 중간형상정보 생성 기법을 제안한다. 마지막으로 활성형상모탤 적합을 통해 반월상 연골 자동 분할을 수행한다. 제안 방법의 평가를 위하여 육안평가와 정확성 평가 그리고 수행시간을 측정하였다. 정확성 평가는 자동 분할과 반자동 분할 결과간의 평균거리차이를 측정하였고 이를 컬러맵으로 표현하였다. 실험 결과 평균거리차이는 내측 반월상 연골은 $0.54{\pm}0.16mm$, 외측 반월상 연골은 $0.73{\pm}0.39mm$으로 측정되었고, 수행시간은 평균 4.87초로 측정되었다.