• Title/Summary/Keyword: Self Restoration

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Transplantation of spermatogonial stem cells in stallions

  • Heejun Jung;Minjung Yoon
    • Journal of Animal Science and Technology
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    • v.66 no.4
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    • pp.635-644
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    • 2024
  • Spermatogonial stem cells originate from gonocytes and undergo self-renewal and differentiation to generate mature spermatozoa via spermatogenesis in the seminiferous tubules of the testis in male mammals. Owing to the unique capacity of these cells, the spermatogonial stem cell transplantation technique, which enables the restoration of male fertility by transfer of germlines between donor and recipient males, has been developed. Thus, spermatogonial stem cell transplantation can be used as an important next-generation reproductive and breeding tool in livestock production. However, in large animals, this approach is associated with many technical limitations and inefficiency. Furthermore, research regrading spermatogonial stem cell transplantation in stallions is limited. Therefore, this review article describes the history and current knowledge regarding spermatogonial stem cell transplantation in animals and challenges in establishing an experimental protocol for successful spermatogonial stem cell transplantation in stallions, which have been presented under the following heads: spermatogonial stem cell isolation, recipient preparation, and spermatogonial stem cell transplantation. Additionally, we suggest that further investigation based on previous unequivocal evidence regarding donor-derived spermatogenesis in large animals must be conducted. A detailed and better understanding of the physical and physiological aspects is required to discuss the current status of this technique field and develop future directions for the establishment of spermatogonial stem cell transplantation in stallions.

The Comparative Research on the Theory of Self-cultivation in Neo-Confucianism and Daesoon Thought (주자학과 대순사상의 수양론 비교 연구)

  • Lee, Gwang-ju
    • Journal of the Daesoon Academy of Sciences
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    • v.24_2
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    • pp.231-270
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    • 2015
  • This thesis examined Chu Hsi's self-cultivation theory as the representative theory of cultivation in Confucianism, while juxtaposing it to self-cultivation theory in Daesoon thought, concentrating on its similarity and difference. Neo-Confucianism is a scholarship which has wielded a tremendous influence upon East Asia, while functioning as an official scholarship for long period up to Yuan, Ming, and Ching period, after achieving its synthesis by Chu Hsi. After 13th century, Neo-Confucianism has been a representative academic system in Confucianism, and self-cultivation theory was in its center. It suggested various virtues that classical scholars have to equip to fulfill the sainthood and the politics of royal road. The self-cultivation theory of Chu Hsi was developed upon the basis of the theory 'Li-Qi' and the theory of mind. Here, the practice of Geokyung(morally awakened state with a reverent spirit in every moment) and Gyeokmul-tsiji(reaching into the utmost knowledge through investigation of things) formed a nucleus of Chu Hsi's self-cultivation theory. While Geokyung was to reveal one's true nature through cultivation of mind, Gyeokmul-tsiji was to demonstrate the complete use of mind's essence and function. Chu Hsi's self-cultivation theory attempted to realize the unity of heaven and man, and through cultivating self and governing people, it also tried to achieve its ideal of the society of Great Union(Daedong). Daesoon Thought is originated from Sangjenim who has descended to this world as a human being called Jeungsan. He went on his circuit to rectify the disorder of heaven and earth for 9 years to rectify the Three worlds of heaven, earth and human being which were faced with total annihilation due to its rule of mutual conflict, while creating an earthly paradise. Respecting the will of Sangjenim, Dojunim established the foundation of Do through launching 'Meukeukdo' and setting tenet, creed and object so that the cultivators (Doins) could believe and respect the truth of Sangje's great itineration (Daesoon). Among those, the two components of creed, which are four fundamental principles and the three fundamental attitudes are of great account as precept and cardinal point. Through this means, the cultivators of Daesoonjinrihoe aspire to guard against self-deception through transforming the human spirit, to realize earthly immortality through renewing human beings, and to create an earthly paradise through transforming the world. This thesis attempted to compare and analyze the theory of self-cultivation in Neo-Confucianism and Daesoon Thought in the aspect of ground, method, and object of cultivation. First, as for the ground of cultivation, the doctrines of Chu-tzu and Daesoon thought place the essence of cultivation on 'heaven'. Yet, whereas the former postulates Taekeuk (the Great Ultimate) as a principle as well as the heaven of a natural order, Daesoon thought postulates Sangenim as the heaven of superintendence as well as the heaven of a natural order, signified as its equation of Daesoon with circle, along with the unity of Meukeuk (Endlessness) and Taegeuk (the Great Ultimate). Further, the doctrine of Chu-zhu and Daesoon thought is identical in the point that both thoughts see mind as the subject of cultivation, while trying to restore a pure essence. Nevertheless, whereas Neo-Confucianism intends to give scope to ability of the complete use of mind's essence and function, Daesoon Thought sees mind as the essence which is used by spiritual beings and as an organ that heaven, earth and human being rely upon as the center of the universe. In the aspect of method of cultivation, the doctrine of Chuzhu lays emphasis on the rational factor in that it brightens its 'myung-deoki'(bright inner virtue),' while trying to correspond to the law of heaven on the basis of 'Geokyung' and 'Gyeokmul-tsiji.' On the contrary, Daesoon thought lays much emphasis on faith factor in that it aspires for human perfection based on the restoration of conscience by cultivating Daesoonjinri with sincerity, reverence and faith along with 'quieting the heart-mind', 'quieting the body', 'respecting the God of the Ninth Heaven', and 'observing ritual practice on the basis of the faith in Sangjenim. Yet, both thoughts have similarities in that cultivation of body forms the basis and that they attempt to realize their ideals through cultivation in daily life while taking 'Guarding against self-deception' as the key method of self-cultivation.' However, the principle of Chu-zhu can be said to be a voluntary and autonomous practice based on scripture of the saint as well as self-reflection. On the other hand, Daesoon thought reveals certain difference in that it combines faith factor with one's self-effort by concentrating on cultivation under the presence of Sangjenim as the object of belief and the spirits of heaven and earth. In the aspect of object of cultivation, both thoughts share similarities in that the saint and the perfected gentleman with a moral virtue as an ideal image of men in both thoughts attempt to realize each of their 'myung-deok' in human nature as a heavenly mandate while respecting morality. Further, they also share similarity in the point that the desirable characters in both thoughts want to participate in harmonious creation and nurturance. Yet, the perfected gentleman with a moral virtue is also characterized by its aim for a new heaven and earth where there is no mutual conflict but mutual beneficence, by promoting the moral influence and virtue of Sangjenim over one's own virtue, while practising the mutual beneficence of all life through harmonious union of divine beings and human beings.

An Exploratory Study on the Business Failure Recovery Factors of Serial Entrepreneurs: Focusing on Small Business (연속 기업가의 사업 실패 회복요인에 관한 탐색적 연구: 소상공인을 중심으로)

  • Lee, Kyung Suk;Park, Joo Yeon;Sung, Chang Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.16 no.6
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    • pp.17-29
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    • 2021
  • Recently, as social distancing have been raised due to the re-spread of COVID-19, the number of serial entrepreneurs who are closing their business is rapidly increasing. Learning from failure is a source of success, but business failure can result in psychological and economic losses and negative emotions of the serial entrepreneur. At this point, it is very important to find a way to recover the negative emotions caused by business failures of serial entrepreneurs. Recently, a strategic model has emerged to deal with the negative emotions of grief caused by business failures of serial entrepreneurs. This study identified the recovery factors from the grief of business failures of serial entrepreneurs and analyzed Shepherd's(2003) three areas: loss orientation, restoration orientation, and dual process. To this end, individual in-depth interviews were conducted with 12 small business serial entrepreneurs who challenged re-startup to identify the attributes of recovery factors that were not identified with quantitative data. As a result of the study, first, recovery factors were investigated in three areas: individual orientation, family orientation, and network orientation. It was found to help improve recovery in nine categories: self-esteem, persistence, personal competence, hobbies, self-confidence, family support, networks, religion, and social support. Second, recovery obstacle factors were investigated in three areas: psychological, economic, and environmental factors. Nine categories including family, health, social network, business partner, competitor, partner, fund, external environment, and government policy were found to persist negative emotions. Third, the emotional processing process for grief was investigated in three areas: loss orientation, restoration orientation, and dual process. Ten categories such as family, partner support, social member support, government support, hobbies, networks, change of business field, moving, third-party perspective, and meditation were confirmed to enhance rapid recovery in the emotional processing process for grief. The implications of this study are as follows. The process of recovering from the grief caused by business failures of serial entrepreneurs was attempted by a qualitative study. By extending the theory of Shepherd(2003), This study can be applied to help with recovery research. In addition, conceptual models and propositions for future empirical research were presented, which can be discussed in carious academic ways.

Middle School Home Economics Teachers' Perception and Needs of Self Supervision Related to Home Economics Subject Matter (중학교 가정과교사의 가정교과관련 자기장학에 대한 인식과 자기장학 활성화를 위한 요구)

  • Nam, Yun-Jin;Chae, Jung-Hyun
    • Journal of Korean Home Economics Education Association
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    • v.20 no.1
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    • pp.45-62
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    • 2008
  • The purpose of this study was to investigate middle school home economics(HE) teachers' perception and needs on self supervision related to HE subject matter, Using the methods of survey and interview, 177 samples were collected. For collected surveys, mean value, standard deviation, frequency, percentage analysis were performed by using an SPSS/Win (ver10.1) program. The results of this study were as follows. First, the middle school HE teachers recognized that self supervision related to HE subject matter was absolutely needed to expand the improvement of techniques for teaching instructions and the width of knowledge on the studies on textbook. Second, the middle school HE teachers recognized the necessary parts of self supervision related to HE subject matter as HE teaching-learning methods, the studies on textbook contents, and HE education philosophy in order. Third, the middle school HE teachers recognized that it would be helpful in improving their HE class and expertise in order of field survey, participation in various training programs, utilization of mass media, participation in societies for researches and meetings and information sharing with co-teachers among the types of self supervision. Fourth, the middle school HE teachers needed the reduction in miscellaneous duties, less pressure for time, restoration of teachers' desire, support of physical resources (improvement of various environments such as classrooms and special rooms), economic support and various support programs (expanding the opportunities to participate in training and society and establishment of a database for relevant materials, etc.) to facilitate self supervision. As such, the middle school HE teachers' overall recognition on HE-related self supervision became significantly higher. To enhance the HE-related expertise, however, it would be necessary to conduct concrete and active support for HE education, philosophical area and the studies on textbook contents as well as the teaching-learning methods for HE in which teachers' demand was high. In addition, the HE teachers wanted to have an easy and quick access to various HE-related data; therefore, it would be urgent to summarize scattered relevant data and support the HE teachers more systematically.

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EFFECT OF INTERMEDIATE RESIN HYDROPHILICITY ON BOND STRENGTH OF SINGLE STEP ADHESIVE (중간레진의 친수성이 상아질 접착에 미치는 영향)

  • Kim, Yong-Sung;Park, Sang-Hyuk;Choi, Gi-Woon;Choi, Kyoung-Kyu
    • Restorative Dentistry and Endodontics
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    • v.32 no.5
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    • pp.445-458
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    • 2007
  • The purpose of this study was to evaluate the bond strength of a new Single step system with different curing mode composites, and to evaluate the effect of the intermediate resins which have different hydrophilicity on bonding ability by means of the micro shear bond testing and TEM examination for the adhesive interface. The adhesive used in this study was an experimental single step system (Bisco Inc., Schaumburg IL). Experimental groups were produced by using six kinds of intermediate resin having different hydrophilicity that was hydrophilic, hydrophobic and most hydrophobic resin and as filled or not after applying adhesive. Each experimental group was further divided into two subgroups whether the adhesive was light cured or not. Dual cured composite (Bis Core, Bisco Ltd., Schaumburg, IL) was placed on the adhesive layer as light cure or self cure mode. The results or bond strength were statistically analyzed using one way ANOVA and multiple comparisons are made using Tukey's test at ${\alpha}\;<\;0.05$ level. The results of this study were as follows ; 1. The application of intermediate resin did not increase the bond strength for light cured composite. 2. The bond strength of an experimental adhesive with self cured composite was significantly increased by the application of intermediate resin layer. 3. The bond strength of adhesive was irrespective of the cure or not of itself before intermediate resin layer applied. 4. As applied hydrophilic resin layer was, the initial bond strength was higher than both hydrophobic and most hydrophobic one used but there was no significance. Using a single step adhesive with dual/self cured composite, the incompatibility between both of them should be solved by the application of intermediate hydrophobic resin to reduce the adhesive permeability. However, Single step adhesive can be used in the light cured composite restoration without any decrease of the initial bond strength.

Fish Distribution and Management Strategy for Improve Biodiversity in Created Wetlands Located at Nakdong River Basin (낙동강 신규조성 습지의 어류 분포와 종다양성 증진을 위한 관리방안)

  • Choi, Jong Yun;Kim, Seong-Ki;Park, Jung-Soo;Kim, Jeong-Cheol;Yoon, Jong-Hak
    • Korean Journal of Environment and Ecology
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    • v.32 no.3
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    • pp.274-288
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    • 2018
  • This study investigated the environmental factors and fish assemblage in 42 wetlands between spring and autumn of 2017 to evaluate the fish distribution and deduce the management strategy for improving biodiversity in created wetlands located at the Nakdong River basin. The investigation identified a total of 30 fish species and found that the most of wetlands were dominated by exotic fishes such as Micropterus salmoides and Lepomis macrochirus. Fish species such as Rhinogobius brunneus, Opsariichthys uncirostris amurensis, Zacco platypus were less abundant in the area with high density of Micropterus salmoides (static area) because they preferred the environment with active water flow. The pattern analysis of fish distribution in each wetland using the self-organizing map (SOM) showed a total of 24 variables (14 fish species and 10 environmental variables). The comparison of variables indicated that the distribution of fish species varied according to water depth and plant cover rate and was less affected by water temperature, pH, and dissolved oxygen. The plant cover rate was strongly associated with high fish density and species diversity. However, wetlands with low plant biomass had diversity and density of fish species. The results showed that the microhabitat structure, created by macrophytes, was an important factor in determining the diversity and abundance of fish communities because the different species compositions of macrophytes supported diverse fish species in these habitats. Based on the results of this study, we conclude that macrophytes are the key components of lentic freshwater ecosystem heterogeneity, and the inclusion of diverse plant species in wetland construction or restoration schemes will result in ecologically healthy food webs.

A Study on the Readaptation of the Women Who have Engaged in Prostitution - A Grounded Theory Approach - (탈성매매여성들의 사회적응에 대한 연구 - 근거이론 방법 접근 -)

  • Kim, Young-sook;Lee, Keun-moo;An, Jun-ri
    • Korean Journal of Social Welfare Studies
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    • no.37
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    • pp.429-455
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    • 2008
  • The purpose of this study is to generate a substantive theory that accounts for the social readaptation of the women who have engaged in prostitution and propose a practical program for them. We used the grounded theory developed by Strauss and Corbin(1990). Raw data were collected through the in-depth interview, documents and observation. We used constant comparative method for the data analysis. The nine women who had the exprience of prostitution have participated in this study. As a result of the data analysis, in open coding were generated 116 concepts, 29 subcategories and 12 categories, In axial coding the outcomes of a paradigm model were as follows. The causal conditions were named 'hostile environment' and 'the self endowed stigma'. The phenomenon turned out to be 'living as an anonymous being'. The contextual conditions were named 'cohesion of family', 'being pushed' and 'shrinked emotion'. The intervening conditions were presented to be 'desire of self restoration as a social being', 'reactionary reconstruction'. The action/interaction strategies turned out to be 'shifting of social status', 'neighbor alliance'. The consequences were presented to be 'psychological wayfarer' and 'tentacular living'. In selective coding we found a core category, 'repetition of leaving and returning from the life world'. Based on the phenomenon, two types of participants life attitudes were found as follows : present hesitating type, self concealing type. Following the adove results, We finally suggested the need to develope a community oriented case management model.

A Study on the Improvement of Response System through the Case of Heavy Rain Disaster Response (폭우재난 대응 사례를 통한 대응체계 개선방안 연구)

  • Woo Sub Shim;Sang Beam Kim
    • Journal of the Society of Disaster Information
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    • v.19 no.3
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    • pp.597-607
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    • 2023
  • Purpose: The Ministry of Employment and Labor has been working hard to ensure the safety of workers due to heavy rain during natural disasters as the responsible ministry in charge of preventing industrial accidents and health problems for workers. Accordingly, the Ministry of Employment and Labor intends to analyze actual cases of responding to heavy rain disasters and suggest ways to improve the response system. Method: An emergency response system implemented to respond to heavy rain disasters with an internal expert group composed of those in charge of disaster work at headquarters, local government offices, and Korea Occupational Safety and Health Agency, and an external expert group composed of professors, consulting representatives, and disaster managers from other ministries. Contents on self-inspection by industry, workplace inspection, use of serious siren, safety management and restoration work guidance were reviewed. Result: First of all, it is necessary to check the regular contact system from time to time, and it is also necessary to prepare and distribute detailed self-checklists for each industry. In addition, it is necessary to check the implementation of self-inspection when inspecting workplaces, and it seems necessary to have measures to increase the readability of information notified through serious disaster sirens. In addition, since safety work is done in the form of a contract, it seems necessary to prepare specific safety guidelines. Conclusion: In order to protect the lives of workers due to seasonal harm and risk factors, unlike the passive coping methods of the past, abnormal weather should not be regarded as an unexpected situation, and it should be actively and preemptively responding beyond the conventional framework.

The Distribution of Patients and Treatment Trends in the Department of Pediatric Dentistry, Yonsei University Dental Hospital for Last 5 Years (최근 5년간 연세대학교 치과대학병원 소아치과의 환자 분포 및 치료 경향)

  • Kang, Chungmin;Lee, Hyoseol;Choi, Hyungjun;Choi, Byungjai;Son, Heungkyu;Lee, Jaeho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.41 no.2
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    • pp.134-144
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    • 2014
  • The aim of this study was to investigate changes in treatment patterns within pediatric dentistry departments by analyzing the distribution of patients and treatment trends. To that end, treatment charts based on electronic medical records (EMR) from the Yonsei University Dental Hospital from 2008 to 2012 were collected and analyzed. The results showed a decrease in the number of new patients and patients cared for by non-specialists, while the number of foreign patients has increased. The under 2 years-old group accounted for a large portion of new patients. Dental caries, dental trauma, and malocclusion ranked as the top complaints. In terms of restoration treatment, the proportion of patients receiving composite resin, amalgam, and sealant has decreased, whereas self-curing glass ionomer and preventive resin restoration have increased. Single-visit endodontic treatment has been increasing, with a decreasing trend in multi-visit endodontic treatment. The rate of conservative pulp treatment, such as pulp capping and pulpotomy, has increased. For reducing patient anxiety, treatments under sedation have increased, especially with the use of nitric oxide. This investigation into the latest treatment trends and patient characteristics is expected to help pediatric dentists to make appropriate treatment plans.

A STUDY ON THE MICROLEAKAGE OF COMPOSITE RESIN AND GLASS IONOMER CEMENT WITH VARYING FILLING METHODS (수복방법에 따른 복합레진 및 글라스아이오노머 시멘트의 변연부 미세누출에 관한 연구)

  • Hwang, Ho-Keel;Park, Joo-Sik
    • Restorative Dentistry and Endodontics
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    • v.21 no.1
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    • pp.174-186
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    • 1996
  • The purpose of this study was to evaluate the adaptability to tooth structure of composite resin and glass ionomer cement according to filling methods. In this study. two class V cavities were prepared on the buccal and lingual surface of each tooth of forty extracted human premolars. and they were randomly assigned into 4 groups with 10 teeth. The cavities of each group were filled with the CLEARFIL FII self curing resin(Control Group), Z-100 light curing resin (Group 1). $Vitremer^{TM}$ light curing glass ionomer cement(Group 2) and Z-100 light curing resin over the $Vitremer^{TM}$ liner(Group 3). The specimens underwent temperature changed from $5^{\circ}C$ to $55^{\circ}C$ five hundred times. After thermocycling. specimens were immersed in 2% methylene blue solution and stored in 100% relative humidity at $37^{\circ}C$ for 24 hours. And then. the specimens sectioned buccolingually. Degree of dye penetration at tooth-restoration interfaces were examined by Tool maker's microscope(x 200) and Image analyzer. The results were as follows : 1. On the occlusal margin. among the experimental groups. the group 2 showed the highest dye penetration($2.40{\pm}0.68$) and the group 3 showed the lowest dye penetration($1.15{\pm}0.37$). There was significant difference among the experimental groups(p<0.001). 2. On the gingival margin, among the experimental groups, the group 1 showed the highest dye penetration($3.30{\pm}0.57$) and the group 2 showed the lowest dye penetration($1.65{\pm}0.49$). There was significant difference among the experimental groups(p>0.001). 3. About total degree of dye penetration, the group 1 showed the highest dye penetration($2.25{\pm}1.17$) and the group 3 showed the lowest dye penetration ($1.43{\pm}0.55$). There was significant difference among the experimental groups(p<0.001). 4. The sum of dye penetration at occlusal margin was less than gingival margin. There was significant difference between occlusal margin and gingival margin (p<0.001). The results showed that differences were more pronounced at the gingival margin. Composite restorations inserted over the glass-ionomer liner demonstrated significantly less leakage than single restoration that used composite resin or glass-ionomer cement.

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