• International Journal of Oral Biology
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• 제45권4호
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• pp.211-217
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• 2020

Molecular mimicry is the most common mechanism that breaches self-tolerance. We previously identified autoantibodies to aquaporin-5 (AQP5) in the sera of patients with Sjögren's syndrome and found that the aquaporin of Prevotella melaninogenica (PmAqp), an oral commensal, is highly homologous to human AQP5. This study aimed to test whether PmAqp can induce anti-AQP5 autoantibodies via molecular mimicry. From the amino acid sequence of PmAqp, an immunizing peptide; i.e., PmE-L, was designed, which contained both the B cell epitope "E" and T cell epitope. C57BL/6 and BALB/c mice were subcutaneously immunized with linear or cyclic forms of PmE-L emulsified in incomplete Freund's adjuvant. The concentrations of the antibodies in sera were measured using enzyme-linked immunosorbent assays. Both linear and cyclic PmE-L induced high levels of antibodies against not only the immunized peptides but also autoantibodies against AQP5E and antibodies against PmE, a Pm homolog of AQP5E. In C57BL/6 mice; however, the cyclic form of PmE-L was more efficient than the linear form in inducing autoantibodies against AQP5E that contained a cyclic epitope. The levels of anti-PmE antibodies and anti-AQP5E autoantibodies showed a strong positive correlation (r = 0.95, p < 0.0005), suggesting molecular mimicry. Collectively, the mice produced anti-AQP5E autoantibodies in response to a PmAqp-derived peptide. This model proved to be useful for studying the mechanisms of autoantibody production by molecular mimicry.

• International Journal of Computer Science & Network Security
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• 제21권7호
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• pp.35-42
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• 2021

In the article, the authors investigate the economic security system in the conditions of the powers transformation. It is substantiated that economic security acts as a certain system that includes components and at the same time acts as a subsystem of the highest order. It is determined that the economic security system of regions acting as a system has its subsystems, which include: production, financial, environmental, innovation, investment and social subsystems. The parameters of the economic security system include relative economic independence, economic stability and self-development of economic systems, and it is proved that an important feature of economic security in addition to its systemic nature is multi-vector. It is substantiated that the monitoring of ensuring the economic security system of the development of economic systems of different levels in the conditions of the powers transformation should contain the analysis of social, economic and ecological development of regions; spheres of possible dangers of the development of regional economic systems; the nature of the threats; the degree of the possibility of threats; time perspective of economic development threats; possible consequences of losses for economic entities; the impact of threats to the object of the economic entities' activity; possible asymmetry of economic development of regional economic entities. Possible threats as a consequence of the powers transformation have been identified. A PEST analysis of the impact of factors of different nature on economic security and the development of regional economic systems in the powers transformation is carried out. A recurrent ratio is proposed for the economic security system in the conditions of the powers transformation.

• International Journal of Contents
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• 제18권2호
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• pp.1-17
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• 2022

As of September 2021, COVID-19 is still seriously impacting people globally. To better control the epidemic, the Chinese government adopted a nationwide quarantine policy at the early stage of the discovery of COVID-19, which has significantly changed people's production and life. China's Douyin app (International version: TikTok) is an extremely influential entertainment and social tool. During COVID-19, a large number of short videos about COVID-19 appeared. Publishers included government agencies, professionals, and self-media. The content released has made Douyin a tool for people to receive COVID-19 information in addition to entertainment and social functions. This is a quantitative study. By exploring the impact of the Douyin app on Chinese college students during COVID-19, this study provides suggestions from the level of social media such as TikTok to enable Korea's epidemic prevention to be more effective. This study established variable questions such as Douyin's information perceived value, information usage channels, information awareness, anti-epidemic policy attitude, trust of public institution and preventive behavioral intention, and conducted a questionnaire survey. Using SPSS to analyze the obtained data, this study found that: 1. The short video information usage channels about COVID-19 in Douyin have a positive impact on the audience's information awareness; 2. The information perceived value in Douyin has a positive impact on the audience's information awareness; 3. Information awareness and trust of public institution in Douyin have a positive impact on the audience's anti-epidemic policy attitude; 4. Information awareness and trust of public institutions in Douyin have a positive impact on the audience's preventive behavioral intention; 5. The audience's anti-epidemic policy attitude has a positive effect on preventive behavioral intention.

• International Journal of Contents
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• 제18권2호
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• pp.47-57
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• 2022

e-Learning content can be defined as digital content to achieve educational goals. Since it is an educational material that can be distributed in offline, online, and mobile environments, it is important to create content that meets the learner's education environment and educational goals. In particular, if the learner is a public official, the vision, philosophy, and characteristics of each local government must reflect. As non-face-to-face online education expands further due to the COVID-19 pandemic, local governments that have relied on onsite education in the past urgently require developing strong basic competency education and special task competency content that reflect regional characteristics. Such e-learning content, however, hardly exists and the ability to independently develop them is also insufficient. In this circumstance, this case study describes the process of self-production of e-learning content suitable for Busan's characteristics by the Human Resource Development (HRD) Institute of Busan City, a local government. The field of instructional design and instructional technology is always evolving and growing by blending technological innovation into instructional platform design and adapting to the changes in society. Busan HRD Institute (BHI), therefore, tried to implement blended learning by developing content that reflected the recent trend of micro-learning in e-learning through a detailed analysis. For this, an e-learning content developer with certain requirements was selected and contracted, and the process of developing content through a collaboration between the client and developer was described in this study according to the ADDIE model of Instructional Systems Development (ISD).

• 반도체디스플레이기술학회지
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• 제21권1호
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• pp.148-154
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• 2022

As the 4th industrial age approaches, the demand for semiconductors is increasing enough to be used in all electronic devices. At the same time, semiconductor technology is also developing day by day, leading to ultraprecision and low power consumption. Semiconductors that keep getting smaller generate heat because the energy density increases, and the generated heat changes the shape of the semiconductor package, so it is important to manage. The temperature change is not only self-heating of the semiconductor package, but also heat generated by external damage. If the package is deformed, it is necessary to manage it because functional problems and performance degradation such as damage occur. The package burn in test in the post-process of semiconductor production is a process that tests the durability and function of the package in a high-temperature environment, and heat dissipation performance can be evaluated. In this paper, we intend to review a new material formulation that can improve the performance of the adapter, which is one of the parts of the test socket used in the burn-in test. It was confirmed what characteristics the basic base showed when polyamide, a high-molecular material, and alumina, which had high thermal conductivity, were mixed for each magnification. In this study, functional evaluation was also carried out by injecting an adapter, a part of the test socket, at the same time as the specimen was manufactured. Verification of stiffness such as tensile strength and flexural strength by mixing ratio, performance evaluation such as thermal conductivity, and manufacturing of a dummy device also confirmed warpage. As a result, it was confirmed that the thermal stability was excellent. Through this study, it is thought that it can be used as basic data for the development of materials for burn-in sockets in the future.

• 국제교류와 융합교육
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• 제2권1호
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• pp.29-41
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• 2022

최근 시각디자인 전공은 많은 국가에서 생산적 가치를 창출하는 신흥 산업으로 부상하고 있으며 시각디자인 교사는 디자이너의 발전과 디자인 산업의 트렌드에도 영향을 미치는 핵심 요소가 되고 있다. 시각디자인 전공 교사들의 역할이 중요해졌다. 본 연구는 대학의 시각디자인 전공 교사를 연구대상으로 하며 그들의 직무를 수행할 때 갖춰야 할 역량의 구성 모델을 연구하고자 한다. 우선 문서 분류를 통해 지식 능력, 교학 능력, 실무능력, 관리능력, 직업윤리인 5가지 역량군을 기반으로 한다. 시각디자인 업계 전문가 10명과의 인터뷰와 2회의 델파이 방식 인터뷰를 통해 시각디자인 교사의 역량을 평가하기 위한 설문지를 개발하도록 한다.

• 한국항행학회논문지
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• 제27권1호
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• pp.102-110
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• 2023

유도탄 체계개발 기간 중 유도탄 기능 점검을 위하여 유도탄 종합점검장비를 제작하여 사용하는데, 장비 제작을 위하여 전원 및 통신 등에 대한 요구사항을 관리한다. 유도탄 종합점검장비 개발자는 유도탄과 통신하는 데이터의 신뢰성 확보를 위하여 제시된 통신 규격에 따라 소프트웨어를 구현한다. 구현 후 테스트베드를 구축하여 자체 성능평가를 수행하고 기준 장비를 이용하여 검증하는 프로세스로 진행하는데, 테스트 베드 구축 시 데이터의 주기적 지연 전송 특성을 반영하여야 한다. 본 논문은 주기적 지연 데이터 처리를 위한 테스트 베드 구축 방법에 대하여 기술하였고, 기존 설계된 알고리즘을 변경하여 성능을 비교 평가 하였다.

• 한국표면공학회지
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• 제56권3호
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• pp.208-218
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• 2023

Photocatalysts are advanced materials which accelerate the photoreaction by providing ordinary reactions with other pathways. The catalysts have various advantages, such as low-cost, low operating temperature and pressure, and long-term use. They are applied to environmental and energy field, including the air and water purification, water splitting for hydrogen production, sterilization and self-cleaning surfaces. However, commercial photocatalysts only absorb ultraviolet light between 100 and 400 nm of wavelength which comprises only 5% in sunlight due to the wide band gap. In addition, rapid recombination of electron-hole pairs reduces the photocatalytic performance. Recently, studies on blackening photocatalysts by laser, thermal, and plasma treatments have been conducted to enhance the absorption of visible light and photocatalytic activity. The disordered structures could yield mid-gap states and vacancies could cause charge carrier trapping. Herein, liquid phase plasma (LPP) is adopted to synthesize Ag-doped black ZnO for the utilization of visible-light. The physical and chemical characteristics of the synthesized photocatalysts are analyzed by SEM/EDS, XRD, XPS and the optical properties of them are investigated using UV/Vis DRS and PL analyses. Lastly, the photocatalytic activity was evaluated using methylene blue as a pollutant.

• Advances in materials Research
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• 제11권2호
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• pp.147-164
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• 2022

This study aims to investigate the influence of scoria aggregate (SA) and silica fume (SF) as a replacement of conventional aggregate and ordinary Portland cement (OPC), respectively. Three types of concrete were prepared namely normal weight concrete (NWC) using limestone aggregate (LSA) and OPC (control specimen), lightweight concrete (LWC) using SA and OPC, and LWC using SA and partial SF (SLWC). The representative workability and compressive strength properties of the developed concrete were evaluated, and the results were correlated with non-destructive ultrasonic pulse velocity and Schmidt hammer tests. The LWC and SLWC yielded compressive strength of around 30 MPa and 33 MPa (i.e., 78-86% of control specimens), respectively. The findings indicate that scoria can be beneficially utilized in the development of structural lightweight concrete. Present renewable sources of aggregate will preserve the natural resources for next generation. The newly produced eco-friendly construction material is intended to break price barriers in all markets and draw attraction of incorporating scoria based light weight construction in Saudi Arabia and GCC countries. Findings of the SWOT analysis indicate that high logistics costs for distributing the aggregates across different regions in Saudi Arabia and clients' resistant to change are among the major obstacles to the commercialized production and utilization of lightweight concrete as green construction material. The findings further revealed that huge scoria deposits in Saudi Arabia, and the potential decrease in density self-weight of structural elements are the major drivers and enablers for promoting the adoption of lightweight concrete as alternative green construction material in the construction sector.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 추계학술대회
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• pp.150-152
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• 2021

자원순환기본법 시행에 따라 국가적으로 자원순환사회 발전을 위해 노력중이다. 이를 위해서는 생산·유통·소비·폐기 등 전 과정에서 폐기물 발생을 억제하고 폐기물 중 재활용가능자원이 단순히 매립·소각되는 대신 재활용되는 것이 중요하다. 하지만 자원순환사회를 만들기 위해서는 배출자. 사업자, 중앙 정부 뿐 아니라 지자체가 함께 노력하고 해결방안을 모색할 필요하다. 이에 본 연구는 국내 제도의 변화와 함께 세종시 현황 및 여건변화를 고려하여 세종시 자원순환사회 발전을 위한 추진 전략을 제시하고자 한다. 지역적으로 재활용 우선 관리 단계별 활성화 방안 마련, 폐기물 자원화의 극대화 및 재활용 산업 활성 방안 마련, 체계적이고 효율적인 재활용 플랫폼 구축 등을 제안한다. 이를 통해 자원순환사회로 도약하고 폐기물이 지속적으로 증가되고 있는 환경문제에 대한 해결책이 될 수 있을 것으로 기대한다.