• 대한치과보철학회지
• /
• 제61권2호
• /
• pp.153-159
• /
• 2023

임플란트를 비롯한 고정성 보철물 제작에 있어서 Computer-aided design-computer-aided manufacturing 기술이 많이 사용되어 왔지만 가철성 의치의 경우 Selective laser melting 방식의 레이저 분말의 융합과정에서 오차가 생기면 융착 부족이나 과융합 등의 오차가 발생하여 정밀도를 크게 손상시킬 수 있어 여전히 기존의 아날로그 방식의 제조법을 사용하고 있다. 최근 CAD 소프트웨어의 발달로 가상의 서베잉과 프레임워크의 디자인이 가능해지고 이렇게 디자인된 형태를 밀링이나 3D 프린팅과 같은 방식으로 제작할 수 있게 되면서 전통적인 의치제작 방식 중 납형 제작이나 온성과 같은 과정을 대체할 수 있게 되었고, 제작 소요되는 시간과 비용을 줄일 수 있다. 따라서 본 증례는 CAD 소프트웨어 상에서 디지털 서베잉을 시행하여 서베이드 금속도재관을 제작하고 금속 프레임워크를 디자인하여 이를 3D 프린팅 하는 디지털 방식의 상하악 가철성 의치를 제작하여 좋은 임상 결과를 얻었기에 보고하는 바이다.

• 한국산학기술학회논문지
• /
• 제14권7호
• /
• pp.3431-3436
• /
• 2013

본 논문은 주파수 선택 표면 (FSS)을 이용한 대역저지 ultra-wideband (UWB) 안테나를 제안한다. 제안된 안테나는 일반적인 FSS 단위 셀의 특성을 이용하여 UWB 대역 중 특정대역을 저지 할 수 있다. 안테나의 FSS 단위 셀구조는 UWB 안테나 구조체와 동일면에 설계하였으며, UWB 대역 (3.1-10.6 GHz) 중 무선 근거리 통신대역(5.15-5.825 GHz)의 간섭을 막기 위해 고안되었다. 제작된 안테나의 실제 측정된 이득은 저지 대역을 제외한 전 대역에서 2 dBi 이상이다. 제안된 안테나는 소형 모바일 장치에 적용이 가능 한 크기이며, 평판형 구조로 설계되어 다양한 FSS 단위 셀에 적용 할 수 있으며, 다양한 상용 UWB 시스템에 적용이 가능하다.

• 열처리공학회지
• /
• 제33권3호
• /
• pp.99-106
• /
• 2020

Selective laser melting (SLM) is an additive manufacturing process by melting metallic powders and stacking into layers, and can product complex shapes or near-net-shape (NNS) that are difficult to product by conventional processes. Also, SLM process is able to raise the efficiency of production by creating a streamlined manufacturing process. For manufacturing in SLM process using Ti-6Al-4V powder, analysis of microstructural evolution and evaluation of mechanical properties are essential because of rapid melting and solidification process of powders according to high laser power and rapid scan speed. In addition, it requires a post-processing because the soundness and mechanical properties are degraded by defects such as pore, un-melted powder, lack-of-fusion, etc. In this study, hot isostatic press (HIP) was conducted as a post-processing on SLM-printed Ti-6Al-4V alloy. Microstructure of post-processed Ti-6Al-4V alloy was compared to as-built Ti-6Al-4V, and the evolution of quasi-static (Vickers hardness, room temperature tensile characteristic) and dynamic (high-cycle fatigue characteristic) mechanical properties were analyzed.

• Journal of Korean Neurosurgical Society
• /
• 제48권5호
• /
• pp.419-422
• /
• 2010

Objective : To analyze the clinical outcomes of computed tomography (CT) fluoroscopy-guided selective neve root block (SNRB) for severe arm pain caused by acute cervical disc herniation. Methods : The authors analyzed the data obtained from 25 consecutive patients who underwent CT fluoroscopy-guided SNRB for severe arm pain, i.e., a visual analogue scale (VAS) score of 8 points or more, caused by acute soft cervical disc herniation. Patients with chronic arm pain, motor weakness, and/or hard disc herniation were excluded. Results : The series comprised 19 men and 6 women whose mean age was 48.1 years (range 35-72 years). The mean symptom duration was 17.5 days (range 4-56 days) and the treated level was at C5-6 in 13 patients, C6-7 in 9, and both C5-6 and C6-7 in 3. Twenty-three patients underwent SNRB in 1 session and 2 underwent the procedure in 2 sessions. No complications related to the procedures occurred. At a mean follow-up duration of 11.5 months (range 6-22 months), the mean VAS score and NDI significantly improved from 9 and 58.2 to 3.4 and 28.1, respectively. Eighteen out of 25 patients (72%) showed successful clinical results. Seven patients (28%) did not improve after the procedure, and 5 of these 7 underwent subsequent anterior cervical discectomy and fusion. Conclusion : CT fluoroscopy-guided SNRB may play a role as a primary conservative treatment for severe arm pain caused by acute cervical disc herniation.

• ALGAE
• /
• 제35권4호
• /
• pp.389-404
• /
• 2020

Red algal fertilization is unusual and offers a different model to the mechanism of intracellular transport of nuclei and polyspermy blocking. A female carpogonium (egg) undergoes plasmogamy with many spermatia (sperm) simultaneously at the receptive structure, trichogyne, which often contains numerous male nuclei. The pattern of selective transport of a male nucleus to the female nucleus, located in the cell body of the carpogonium, remain largely unknown. We tracked the movement of spermatial nuclei and cell organelles in the trichogyne after plasmogamy using time-lapse videography and fluorescent probes. The fertilization process of Bostrychia moritziana is composed of five distinctive stages: 1) gamete-gamete binding; 2) mitosis in the attached spermatia; 3) formation of a fertilization channel; 4) migration of spermatial nuclei into the trichogyne; and 5) cutting off of the trichogyne cytoplasm from the rest of the cell after karyogamy. Our results showed that actin microfilaments were involved in the above steps of fertilization, microtubules are involved only in spermatial mitosis. Time-lapse videography showed that the first ("primary") nucleus which entered to trichogyne moved quickly to the base of carpogonium and fused with the female nucleus. The transport of the primary male nucleus to the egg nucleus was complete before its second nucleus migrated into the trichogyne. Male nuclei from other spermatia stopped directional movement soon after the first one entered the carpogonial base and oscillated near where they entered trichogyne. The cytoplasm of the trichogyne was cut off at a narrow neck connecting the trichogyne and carpogonial base after gamete nuclear fusion but gamete binding and plasmogamy continued on the trichogyne. Spermatial organelles, including mitochondria, entered the trichogyne together with the nuclei but did not show any directional movement and remained close to where they entered. These results suggest that polyspermy blocking in B. moritziana is achieved by the selective and rapid transport of the first nucleus entered trichogyne and the rupture of the trichogyne after gamete karyogamy.

• Applied Microscopy
• /
• 제39권3호
• /
• pp.277-281
• /
• 2009

Practical difficulties for preparing a good crosssectional specimen of GaN-based materials for transmission electron microscopy have arisen due to large difference of mechanical properties between hard ceramic substrate and soft GaN-layered materials. Uneven polishing, sudden cracking, delamination, and selective sputtering during the conventional wedge polishing technique are often encountered as experimental hindrances. The preparation technique based on Strecker's method can be applied to overcome these difficulties, which eventually leads to mechanically stable TEM samples independent of the mechanical properties of materials. The basic idea is to use hard ceramic dummy filler for embedding the sample of interest into the dummy frame. In this study, we applied this technique into preparing cross-sectional TEM specimen of the GaN-based materials with mechanical instability and demonstrated usefulness of this hard dummy filler method in which the possible modifications of the sample of interest during the preparation must be avoidable. In addition, practical precautions during the preparation were discussed.

• Composites Research
• /
• 제34권4호
• /
• pp.212-225
• /
• 2021

금속 기지재 복합재료들(MMCs, Metal matrix composites)은 우수한 기계적 물성(강성, 강도, 마모 저항성, 경도 등)과 뛰어난 특성(열전도, 전기전도도, 부식 저항 등)으로 다양한 산업군에 활용되고 있다. 적층제조 기술이 발달함에 따라 복잡한 형상을 시간과 비용을 절약하여 제조할 수 있다는 이점으로, 적층 제조한 MMCs에 관한 연구가 활발하게 이루어지고 있다. 하지만 MMCs를 적층 제조할 경우, 다양한 원인들에 의해 여러 문제들이 발생할 수 있다. 따라서 본 연구에서는 다양한 MMCs의 특징들을 소개하고, 위의 문제들이 발생하는 원인을 고찰하여 소재와 Powder bed fusion (PBF) 공정 설계 관점에서 해결책을 제시하고자 한다. 본 논문은 향후 PBF 방식으로 적층 제조한 MMCs를 개발할 때 설계 및 제조 가이드라인을 제시하여 줄 수 있을 것이다.

• Molecules and Cells
• /
• 제25권1호
• /
• pp.55-63
• /
• 2008

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the selective death of motor neurons. Mutations in the SOD1 gene are responsible for a familial form of ALS (FALS). Although many studies suggest that mutant SOD1 proteins are cytotoxic, the mechanism is not fully understood. To investigate the role of mutant SOD1 in FALS, human SOD1 genes were fused with a PEP-1 peptide in a bacterial expression vector to produce in-frame PEP-1-SOD fusion proteins (wild type and mutants). The expressed and purified PEP-1-SOD fusion proteins were efficiently transduced into neuronal cells. Neurones harboring the A4V, G93A, G85R, and D90A mutants of PEP-1-SOD were more vulnerable to oxidative stress induced by paraquat than those harboring wild-type proteins. Moreover, neurones harboring the mutant SOD proteins had lower heat shock protein (Hsp) expression levels than those harboring wild-type SOD. The effects of the transduced SOD1 fusion proteins may provide an explanation for the association of SOD1 with FALS, and Hsps could be candidate agents for the treatment of ALS.

• 한국지하수토양환경학회지:지하수토양환경
• /
• 제18권1호
• /
• pp.112-122
• /
• 2013

Current status of soil contamination with fluorine and its source were investigated. The basic principles and procedures of various techniques for the analysis of fluorine contents in soil and solid phase samples were summarized in this review. Analysis of fluorine in solid matrices can be achieved by two types of techniques: (i) UV/Vis spectrophotometer or ion selective electrode (ISE) analysis after performing appropriate extraction steps and (ii) direct solid analysis. As the former cases, the standard method of Korean ministry of environment, alkali fusion-ISE method, pyrohydrolysis, oxygen bomb combustion, aqua regia digestion-automatic analysis, and sequential extraction-ISE method were introduced. In addition, direct analysis methods (i.e., X-ray fluorescence spectrometry and proton induced gamma-ray emission spectrometry) and atomic spectrometry combining with the equipment for introducing solid phase sample were also reviewed. Fluorine analysis techniques can be reasonably selected through site-specific information such as matrix condition, contamination level, the amount of samples and the principles of various methods for the analysis of fluorine presented in this review.

• Journal of Korean Neurosurgical Society
• /
• 제30권6호
• /
• pp.743-748
• /
• 2001

Objective : To evaluate the effectiveness of posterior microforaminotomy in treatment of posterolateral cervical disc herniation, the authors retrospectively analyzed the result of posterior microforaminotomy in our institute. Patients and Methods : Ten patients with radiculopathy due to posterolateral cervical disc herniation have been treated with posterior microforaminotomy from August 1996 to July 2000. We analyzed clinical results in all patients who were followed up for an average of 10 months. Results : The mean age was 47.2 years and all patients were treated with posterior microforaminotomy as primary treatment. one patient was received anterior cervical interbody fusion with iliac bone 12 years before. Clinical improvement in the last follow-up were seen in all patients and there were no complications. Conclusion : Microcervical foraminotomy is considered useful operative method for posterolateral soft disc herniation. We conclude that the posterior microforaminotomy for radiculopathy due to soft posterolateral cervical disc herniation seems to be safe and effective in selective patients.