• Journal of Chest Surgery
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• v.55 no.1
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• pp.10-19
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• 2022

Background: According to the eighth TNM (tumor-node-metastasis) staging system, the presence of separate tumor nodules in the same lobe is designated as a T3 descriptor. However, it remains unclear whether adjuvant chemotherapy confers survival advantages in this setting. Methods: We retrospectively identified 142 pathologic T3N0M0 patients with additional pulmonary nodules in the same lobe from a single-institutional database from 2004 to 2019. The main outcomes were overall survival and recurrence-free survival. Multivariable Cox regression was used to identify the benefit of adjuvant chemotherapy while adjusting for other variables. Results: Sixty-one patients received adjuvant chemotherapy (adjuvant group) and 81 patients did not receive adjuvant therapy after surgery (surgery-only group). There were no demonstrable differences between the 2 groups regarding hospital mortality and postoperative complications, indicating that treatment selection had not significantly occurred. However, the use of adjuvant chemotherapy was associated with improved 5-year overall survival (70% vs. 59%, p=0.006) and disease-free survival (60% vs. 46%, p=0.040). A multivariable Cox model demonstrated that adjuvant chemotherapy was associated with a survival advantage (adjusted hazard ratio, 0.54; p<0.001). In exploratory analyses of subgroups, the effect of adjuvant chemotherapy seemed to be insufficient in those with small main tumors (<4 cm). Conclusion: Adjuvant chemotherapy was associated with better survival in T3 cancers with an additional tumor nodule in the same lobe. However, the role of adjuvant chemotherapy in patient subgroups with small tumors or those without risk factors should be determined via large studies.

• Therapeutic Science for Rehabilitation
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• v.11 no.4
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• pp.55-68
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• 2022

Objective : This review aimed to provide information for clinical application by confirming the principles and characteristics of the tool through a review of tongue movement and measurement tools for patients with swallowing disorders. Results : We identified 15 tools used as tongue exercises and measurement tools in the field of dysphagia. According to principle, the tools were classified as either a bulb sensor, resistive sensor sheet, mouthpiece with sensor, or other techniques. The bulb sensor was easy to use but had limitations in fixing the position when measuring tongue pressure. The resistive sensor sheet could be measured at a more stable position than the bulb sensor. A mouthpiece with a sensor could be used in an individual's oral cavity such that the position was fixed when measuring the tongue pressure. Other techniques had the advantage of being wireless and capable of sensing light. Conclusion : Based on this literature review, it is necessary to facilitate the selection of the best tool for quantitative tongue measurement in dysphagia. The review can also be used to develop a Korean tongue movement tool model that can be used in hospitals and community centers.

• Journal of The Korean Society of Agricultural Engineers
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• v.64 no.3
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• pp.9-24
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• 2022

Currently, a vast amount of hydrologic data is accumulated in real-time through automatic water level measuring instruments in agricultural reservoirs. At the same time, false and missing data points are also increasing. The applicability and reliability of quality control of hydrological data must be secured for efficient agricultural water management through calculation of water supply and disaster management. Considering the characteristics of irregularities in hydrological data caused by irrigation water usage and rainfall pattern, the Korea Rural Community Corporation is currently applying the Hampel filter as a water level data quality management method. This method uses window size as a key parameter, and if window size is large, distortion of data may occur and if window size is small, many outliers are not removed which reduces the reliability of the corrected data. Thus, selection of the optimal window size for individual reservoir is required. To ensure reliability, we compared and analyzed the RMSE (Root Mean Square Error) and NSE (Nash-Sutcliffe model efficiency coefficient) of the corrected data and the daily water level of the RIMS (Rural Infrastructure Management System) data, and the automatic outlier detection standards used by the Ministry of Environment. To select the optimal window size, we used the classification performance evaluation index of the error matrix and the rainfall data of the irrigation period, showing the optimal values at 3 h. The efficient reservoir automatic calibration technique can reduce manpower and time required for manual calibration, and is expected to improve the reliability of water level data and the value of water resources.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.3
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• pp.163-169
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• 2022

According to the Credit Information Act, in order to protect customer information by relationship of credit information subjects, it is destroyed and stored separately in two stages according to the period after the financial transaction effect is over. However, there is a limitation in that the destruction of personal credit information of customers whose financial transaction effect has expired cannot be collectively destroyed when the transaction has been terminated, depending on the nature of the financial product and transaction. To this end, the IT person in charge is developing a computerized program according to the target and order of destruction by investigating the business relationship by transaction type in advance. In this process, if the identification of the upper relation between tables is unclear, a compliance issue arises in which personal credit information cannot be destroyed or even information that should not be destroyed because it depends on the subjective judgment of the IT person in charge. Therefore, in this paper, we propose a model and algorithm for identifying the referenced table based on SQL executed in the computer program, analyzing the upper relation between tables with the primary key information of the table, and visualizing and objectively selecting the range to be destroyed. presented and implemented.

• Journal of Bio-Environment Control
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• v.32 no.1
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• pp.72-80
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• 2023

Melons, a rich source of vitamins and fibers, are commonly grown in the soil. Hydroponic cultivation could improve yield and quality of melon and selection of substrate volume and the kind of substrates is important for hydroponic cultivation of melons. This study investigated the effect on melon growth according to volume of granular rockwool and substrates of coir and rockwool slab. 'Geumsegye' melon (Cucumis melo L. cv. Geumsegye) was cultivated hydroponically according to volume of granular rockwool to 1.0, 1.5, 2.0, 3.0, and 4.0 L, and was also cultivated using coir and rockwool slabs. Logistic model was applied to estimate the growth characteristics of melons such as plant height, leaf length, leaf width, and the characteristics of fruit. The growth characteristics of melons were significantly increased at 4.0 L compared to those grown of 1.0 L volume of on granular rockwool, and the results were the highest in coir and rockwool slabs. Melons grown in rockwool slabs showed the largest fruit fresh weight, fruit length, and fruit width. During hydroponic cultivation, growth characteristics of melon appropriate at the 4.0 L volume of granular rockwool, and the highest at coir and rockwool slabs. This study provides a basis for understanding the effect of root zone environment to the growth characteristics and fruit quality of non-netted melon.

• Smart Media Journal
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• v.11 no.10
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• pp.89-96
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• 2022

An open domain machine reading comprehension is a model that adds a function to search paragraphs as there are no paragraphs related to a given question. Document searches have an issue of lower performance with a lot of documents despite abundant research with word frequency based TF-IDF. Paragraph selections also have an issue of not extracting paragraph contexts, including sentence characteristics accurately despite a lot of research with word-based embedding. Document reading comprehension has an issue of slow learning due to the growing number of parameters despite a lot of research on BERT. Trying to solve these three issues, this study used BM25 which considered even sentence length and InferSent to get sentence contexts, and proposed an open domain machine reading comprehension with ALBERT to reduce the number of parameters. An experiment was conducted with SQuAD1.1 datasets. BM25 recorded a higher performance of document research than TF-IDF by 3.2%. InferSent showed a higher performance in paragraph selection than Transformer by 0.9%. Finally, as the number of paragraphs increased in document comprehension, ALBERT was 0.4% higher in EM and 0.2% higher in F1.

• Journal of Animal Reproduction and Biotechnology
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• v.37 no.4
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• pp.292-297
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• 2022

Direct injection of CRISPR/Cas9 into zygotes enables the production of genetically modified nonhuman primates (NHPs) essential for modeling specific human diseases, such as Usher syndrome, and for developing novel therapeutic strategies. Usher syndrome is a rare genetic disease that causes loss of hearing, retinal degeneration, and problems with balance, and is attributed to a mutation in MYO7A, a gene that encodes an uncommon myosin motor protein expressed in the inner ear and retinal photoreceptors. To produce an Usher syndrome type 1B (USH1B) rhesus macaque model, we disrupted the MYO7A gene in developing zygotes. Identification of appropriately edited MYO7A embryos for knockout embryo transfer requires sequence analysis of material recovered from a trophectoderm (TE) cell biopsy. However, the TE biopsy procedure is labor intensive and could adversely impact embryo development. Recent studies have reported using cell-free DNA (cfDNA) from embryo culture media to detect aneuploid embryos in human in vitro fertilization (IVF) clinics. The cfDNA is released from the embryo during cell division or cell death, suggesting that cfDNA may be a viable resource for sequence analysis. Moreover, cfDNA collection is not invasive to the embryo and does not require special tools or expertise. We hypothesized that selection of appropriate edited embryos could be performed by analyzing cfDNA for MYO7A editing in embryo culture medium, and that this method would be advantageous for the subsequent generation of genetically modified NHPs. The purpose of this experiment is to determine whether cfDNA can be used to identify the target gene mutation of CRISPR/Cas9 injected embryos. In this study, we were able to obtain and utilize cfDNA to confirm the mutagenesis of MYO7A, but the method will require further optimization to obtain better accuracy before it can replace the TE biopsy approach.

• Journal of the Korean Society of Earth Science Education
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• v.16 no.1
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• pp.56-71
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• 2023

The purpose of this study is to explore the role and effectiveness of argumentation structure and the developmental characteristics of science PCK with Earth science preservice teachers who used argumentation structure as a pedagogical reasoning tool. Since teachers demonstrate PCK in a series of pedagogical reasoning processes using argumentation structures, we explored the characteristics of future-oriented family resemblance-PCK shown by preservice science teachers using argumentation structures. At the end of the semester, we conducted in-depth interviews with 15 earth science preservice teachers who had experienced lesson design and teaching practice using the argumentation structure. Qualitative analysis including a semantic network analysis was conducted based on the in-depth interview to analyze the characteristics of preservice teachers' family resemblance-PCK. Results include that preservice teachers organized their classes systematically by applying the argumentation structure, and structured classes by differentiating argumentation elements from facts to conclusions. Regarding the characteristics of each component of the argumentation structure, preservice teachers had difficulty finding warrant, rebuttal, and qualifier. The area of PCK most affected by the argumentation structure is the science teaching practice, and preservice teachers emphasized the selection of a instructional model suitable for lesson content, the use of various teaching methods and inquiry activities to persuade lesson content, and developing of data literacy and digital competency. Discussed in the conclusion are the potential and usability of argument structure as a pedagogical reasoning tool, the possibility of developing science inquiry and reasoning competency of secondary school students who experience science classes using argumentation structure, and the need for developing a teacher education protocol using argumentation structure as a pedagogical reasoning tool.

• Journal of Korea Entertainment Industry Association
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• v.13 no.8
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• pp.377-389
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• 2019

This study conducted social network big data analysis to investigate consumer's perception of Japanese sporting goods related to Japanese boycott and to extract problems and variables by recognition. Social network big data analysis was conducted in two areas, "Japanese boycott" and "Japanese sporting goods". Months of data were collected and investigated. If you specify the research method, you will identify the issues of the times - keyword setting using social network analysis - clustering using CONCOR analysis using TEXTOM and Ucinet 6 programs - variable selection through expert meetings - questionnaire preparation and answering - and validity of questionnaire Reliability Verification - It consists of hypothesis verification using the structural model equation. Based on the results of using the big data of social networks, four variables of relevant characteristics, nationality, attitude, and consumption behavior were extracted. A total of 30 questions and 292 questionnaires were used for final hypothesis verification. As a result of the analysis, first, the boycott-related characteristics showed a positive relationship with nationality. Specifically, all of the characteristics related to boycotts (necessary boycott, sense of boycott, and perceived boycott benefits were positively related to nationality. In addition, nationality was found to have a positive relationship with consumption behavior.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.317-321
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• 2022

In response to Incheon tap water accident in 2019, the Ministry of Environment has created the "Comprehensive Measures for Water Safety Management" to improve water operation management, provide systematic technical support, and respond to accidents. Accordingly, K-water is making a smart water supply management system for the entire process of tap water. In order to advance the response to water accidents, it is essential to secure the reliability of real-time water operation data such as flow rate, pressure, and water level, and to develop and apply a warning algorithm in advance using big data analysis techniques. In this paper, various statistical techniques are applied using water supply operation data (flow, pressure, water level, etc) to prepare the foundation for the selection of the optimal operating range and advancement of the monitoring and alarm system. In addition, the arrival time is analyzed through cross-correlation analysis of changes in raw water turbidity between the water intake and water treatment plants. The purpose of this paper is to study the model that predicts the raw water turbidity of a water treatment plant by applying raw water turbidity data considering the time delay according to the flow rate change.