This study was conducted to establish the rapid determination method for major components of maturing covered barley grains, and to improve the efficiency of selection in barley breeding. Near Infrared Reflectance Spectroscopy (NIRS) is an established, economical and nondestructive technique applied widely to the food and feed industry. 34 barley lines were sampled at 5 day-interval from 25 to 35 days after heading. A standard regression analysis for the data obtained by analytical laboratory methods and NIRS method was carried out to get a useful calibration equation. The simple significant correlation between these two methods at 25 days after heading was recognized in starch and $\beta$-glucan contents. At 30 days after heading the data obtained by two methods showed significant correlation in starch, $\beta$-glucan and protein contents. Analyzed data and that from NIRS method at 35 days after heading was significantly correlated in starch and protein contents. It was concluded that the applicability of NIRS method for the components analysis in maturing barley grains was different depending on maturing stages and components.
Proceedings of the Korean Society of Toxicology Conference
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2006.11a
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pp.65-74
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2006
Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.31
no.4
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pp.269-275
/
2013
Recently, importance of pedestrian road network is getting emphasized as it is possible to provide mobile device users with both route guidance services and surrounding spatial information. However, it costs a tremendous amount of budget for generating and renovating pedestrian road network nationally, which hinder further advances of these services. Hence, algorithms extracting pedestrian road network automatically based on raster data are needed. On the other hand, road dataset generated from raster data usually has unnecessary vertices which lead to maintenance disutility such as excessive turns and increase in data memory. Therefore, this study proposed a method of selecting a proper threshold automatically for separate road entity using not only Douglas-Peucker algorithm but also road attribute data of digital map in order to remove redundant vertices, which maximizes line simplification efficiency and minimizes distortion of shape of roads simultaneously. As a result of the test, proposed method was suitable for automatic line simplification in terms of reduction ratio of vertices and accuracy of position.
Kim, Gun-Yeob;Park, Sang-Il;Song, Beom-Heon;Shin, Yong-Kwang
Korean Journal of Environmental Agriculture
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v.21
no.2
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pp.136-143
/
2002
Emission of methane and nitrous oxide affected by nitrogen fertilizer materials were measured simultaneously in rice paddy fields under flooding and intermittent irrigation in 2000. Studies focused on mitigating $CH_4$ emission from rice paddy fields are summarized and the possibilities and limits applied to world's rice cultivation are discussed. The mitigation options are water management, soil amendments, organic matter management, different tillage, rotation, and cultivar selection. Altering water management, in particular promoting midseason aeration by short-term drainage, is one of the most promising strategies, although these practices may be limited to the rice paddy fields where the irrigation system is well prepared. The test site was divided into two water managements: a continuously flooded plot which was maintained flooded by constant irrigation from May to September, and an intermittently drained plot in which short-term (20days) draining practices were performed one times during the flooding period. By total emission of GHGs converted by global warming potential (GWP), flooding plots were higher 170$\sim$208% than interimittent irrigation plots. For emission of GHGs in fertilizer materials, it was high in the order of Swine slurry>Urea+Rice straw>Urea>LCU. Basing on GHGs emission of urea fertilization under flooding as baseline GWP of urea fertilization and Latex-coated urea under intermittent irrigation showed lower GHGs emission by 41.4% and 55.8 respectively. In this case fertilizer use efficiency (kg unhulled rice/ of applied N) were 18.2$\sim$20.2 and 18.7$\sim$19.0 and 9.3 and 5.8$\sim$6.6 for Swine slurry and LCU and Urea+Rice straw and Urea in the continuously flooded and intermittently drained plot.
It is widely recognized that the embryonic or fetal loss after breeding is common in the cattle and that it is an important factor affecting reproductive efficiency. The causes of this loss have been subject of extensive researches and the results indicate that the embryonic mortality may he primary factor responsible for low pregnancy rates in non-embryo transfer bovine populations as well as embryo transfer programs. However, it's causes are still not clearly understood. The embryonic mortality or pregnancy rate has been influenced by various embryonic and maternal effects related to genetic and environmental factors. The timing and extent of embryonic mortality vanes greatly according to authors and estimating methods, because it is difficult to make direct measurements. The major important factors that may influence the embryonic losses or pregnancy rates after embryo transfer can be summeirized. 1.When an embryo is transferred to unmated recipients, the contralateral transfer to corpus luteum results in a lower survival rate than ipsilateral deposition. When the embryos are transferred for the production of twin calves, their survivals and twin pregnancies have quite inconsistent according to the transfer methods either to the unmated-synchronized or already mated recipients and more works are needed to accurrately clarify the previous results. 2.Although embryos can be cultured in vitro some hours without the great declines in pregnancy rates, the rates differ markedly among culture times and media but may be improved by co-transfer systems. 3.Embryo developmental stages and quality grades clearly affect the survival rate following freezing and the pregnancy rate after transfer and the selection of embryos without chromosome abnormalities and of high fertile semen may also be considered to increase the pregnancy rates. 4.Many researches have attempted to relate the plasma progesterone levels to pregnancy rates and others have done either direct progesterone supplementation or luteal stimulation by hCG treatment in order to increase the pregnancy rates. However, these effects on pregnancy rates are inconsistent and also contradictory. 5.The asynchrony between donors or embryos and recipients may he a major cause of embryo death and low pregnancy rate and the sensitivity to uterine asynchyony differs in according to the quality and stages of embryos. 6.The extremes of poor or over nutrition during early pregnancy in the recipients are detrimental to the survival of embryos and the good body condition is required to prevent a reduejion of pregnancy rates. The uterine pathogens in embryonic mortality or fertility have been questioned but the infection of C.pyogenes and Campylobacter fetus is still important pathogens. 7.The heat stress during early pregnancy may reduce conceptus weight and possibly increase the embryonic mortality.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
/
v.28
no.2
/
pp.273-280
/
2010
This study aims to research into a plan for the spatial design on the major facilities in new-town region in Mongolia by using the spatial analytical technique in GIS. In case of Mongolian region, the demand for new-town development is rapidly increasing around Ulaanbaatar, where is the capital. On the other hand, the adequately relevant ground or the spatial-design technique is failing to be applied. This study extracted the region available for developing new down by using spatial analytical technique in GIS, and researched into the spatial-design plan for housing complex, filtration plant, sewage disposal plant, power plant, general park, crematory. The housing complex in the targeted region could be known to be adequate to be positioned around watercourse and road. It could be known to be adequate for filtration plant, which is the source of drinking water, to be located in the upper-stream region of a river, which is secured good quality of water, and for sewage disposal plant to be located in the lower-stream region available for minimizing occurrence of contamination. It is judged to be required for a proposed site of power plant to be located in the upper-stream region, for the park unit, which is space of the living culture, to be repaired and expanded the existing facilities, and for traffic network to be expanded through predicting demand along with new-town development. It is judged to be probably needed to be reflected even the flexible aspect for changing design through surveying the feasibility and economic efficiency on the future spatial design.
The Journal of Korean Institute of Electromagnetic Engineering and Science
/
v.14
no.8
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pp.845-854
/
2003
In this paper, the characteristics of compensation for WDM channel signal distortion due to both chromatic dispersion and Ken effect in 1,000 km 200 Gbps(5${\times}$40 Gbps) WDM systems was investigated. The WDM system has a path-averaged intensity approximation(PAIA) mid-span spectral inversion(MSSI) as a compensation method. This system has a highly nonlinear dispersion shifted fiber(HNL-DSF) optical phase conjugator(OPC) in the mid-way of transmission line. In order to evaluate the degree of compensation, 1 dB eye opening penalty(EOP), bit error rate(BER) characteristics and power penalty of 10$\^$-9/ BER are used. It is confirmed that HNL-DSF is an useful nonlinear medium in OPC fur wideband WDM system with PAIA MSSI and that the optimal compensation for WDM channel distortion is achieved by the selection of pump light power of OPC, which equalize the conjugated light power into the second half fiber section with the input WDM signal light power depending on total transmission length, dispersion coefficient of fiber, OPC pump light wavelength, conversion efficiency of WDM channel in OPC.
The Journal of Korean Institute of Communications and Information Sciences
/
v.42
no.4
/
pp.768-779
/
2017
Recently, the great number of mobile devices causes excessive data/control traffic problems in the centralized LTE/EPC network and such dramatically increased traffic is emerging as a critical issue. In the Centralized Mobility Management (CMM) based LTE/EPC network, the Packet Data Network Gateway (P-GW) plays the centralized mobility anchor role and it accommodates most of data traffic. To solve this problem, the IETF has proposed the Distributed Mobility Management (DMM) scheme, but it has only focused on the data traffic load balancing and could not solve the control traffic overload problem. In this paper, therefore, we propose a new SDN based hybrid CMM/DMM Mobility Management (C-DMM) architecture based on Packet Network Edge Gateway (P-EGW), and introduce a selection scheme between CMM and DMM according to a device's mobility and the number of PDN connections. In order to prove the efficiency of the proposed architecture and scheme, we compare the data traffic processing load and the control traffic processing load over each scheme by emulating them in the ONOS controller and the Mininet environment.
As geopolitical, archaeological and strategic interests on cooperation with countries in the Far Eastern Area is gradually increased, countries are competing to attract or install a logistics or manufacturing hub in their countries. In this study, we investigated the relative importance of factors on the main three and nine detailed criteria from the domestic and overseas experts on Far Eastern Area. Using AHP(Analytic Hierarchy Process) analysis, priority importance of factors was derived. As a result, we find that the most important factor was economic factor. In detail, industrial complex creation was the highest factor and the institutional guarantees for the investment on policy and transportation network was second highest factor. Based on analysis result, specific competitiveness level in the 10 region of Far East was follows. Hunchun, Vladivostok, Yanji, Tumen, Rajin, Hassan, Ussuriysk, Cheongjin, Mihaylov Skiing, Nije Jeuchinski were showed in order. Hunchun showed the highest competitive level in location, topography, compliance to the around cities, transportation network, industrial complex, excellence in logistics facilities, long-term investment plans, institutional guarantees for investment, customs efficiency and political stability. However, in other factors such as population and number of households, public facilities, potential demand and resource utilization, Vladivostok showed the highest level.
This study aimed to evaluate conditions and performance of quality improvement (QI) activity in Korean dental hospitals. Twenty one representative dental hospitals in Korea were selected by the selection criteria. A questionnaire was implemented to measure awareness, perceived needs, educations, conferences, works, activating/obstructive factors and satisfaction related to QI activities. Satisfaction score range from 0 (lowest) to 5 (highest) among 329 dental hygienists who worked in the selected 21 dental hospitals. Implementation rate of programs on external customer satisfaction was the highest 59.9% in QI activities, and reduction of expenses (59.4%), Improvement in health care quality (58.7), risk management (52.8) were followed, while improvement in work efficiency (46.5) showed the lowest implementation rate. The most influencing factor accelerating QI activities was 'active participation of hospital workers' (54.7%), and 'effort to improve customer satisfaction' (44.7%) followed. The most influencing QI related obstructive factor was 'lack of QI-related manpower and support' (47.1%). A balanced development including QI programs with lower implementation rates is necessary. Encouraging participation of workers may be the most important in developing dental QI activities further.
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