• Genomics & Informatics
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• v.13 no.4
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• pp.146-151
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• 2015

Previous studies in Holstein have shown 35% to 51.8% heritability in milk production traits, such as milk yield, fat, and protein, using pedigree data. Other studies in complex human traits could be captured by common single-nucleotide polymorphisms (SNPs), and their genetic variations, attributed to chromosomes, are in proportion to their length. Using genome-wide estimation and partitioning approaches, we analyzed three quantitative Holstein traits relevant to milk production in Korean Holstein data harvested from 462 individuals genotyped for 54,609 SNPs. For all three traits (milk yield, fat, and protein), we estimated a nominally significant (p = 0.1) proportion of variance explained by all SNPs on the Illumina BovineSNP50 Beadchip ($h^2_G$). These common SNPs explained approximately most of the narrow-sense heritability. Longer genomic regions tended to provide more phenotypic variation information, with a correlation of 0.46~0.53 between the estimate of variance explained by individual chromosomes and their physical length. These results suggested that polygenicity was ubiquitous for Holstein milk production traits. These results will expand our knowledge on recent animal breeding, such as genomic selection in Holstein.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.1
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• pp.90-100
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• 2015

There are a lot of effort to improve medical service quality and medical trust in Korean Medicine. However, in spite of importance of personalized medicine, there are still few research about it. Thus, the purpose of this study is to grope ways to improve medical service quality and medical trust by sympathy module group and personalized trust. People over 19 were participated in investigation. We divided respondents into 4 groups depending on sympathy module group and 2 groups depending on speed of trust. Questionnaire was consisted of questions about sympathy module group, speed of trust, medical service quality, medical trust, satisfaction and happiness. This questionnaires were conducted through personal interviews. Total 220 members responded to the survey and the results of the analysis were as follows. Rational type had the highest proportion. At Medical service quality scale, Prevention focus group had most highest figure on Confidence. Promotion focus group and Rational Group had most highest figure on Sympathy. At Medical trust scale, Medical team had the highest proportion at all group. Prevention focus group put more emphasis on sense of sanitation, At Satisfaction and Happiness scale, Satisfaction and Happiness was most affected by Trust in Sincerity and Ability. This study can be very useful for composing kit of treatment of personalized medicine. But this study has also some limits such as respondent selection, disease selection etc. So, more detailed and comprehensive survey is needed.

• Proceedings of the Korea Concrete Institute Conference
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• 1998.10a
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• pp.262-268
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• 1998

This research is to examine the selected method of optimal mixing proportion and cost analysis in the super flowing concrete. As confined water $ratio($\beta_p$)$ and K is introduced, itis to establish optimal mixing design of super flowing concrete according to the steps of paste, mortar and concrete. From paste and mortar test, it was led to $$\beta_p$$ and $K_p$satisfying the optimum condions depending on the kinds of binders. Then $$\beta_p$$ and $K_p$ is reflected to the mix condition of super flowing concrete. The result of test, the mix condition of super flowing concrete satisfied the quality performance of concrete with adjustment of additional rate of the superplasticizer. Besides, in case of design strength $350kg/\textrm{cm}^2$ of concrete, material cost in super flowing concrete is able to be reduced 5~16% in replacement of fly ash 30% in ordinary portland cement and slag cement.

• Journal of Nutrition and Health
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• v.17 no.3
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• pp.236-241
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• 1984

In order to make clear the relationship between sample design and sample survey in community, it was conducted research on sample design for National Nutrition Survey in 1983. In this paper it was tried to analize the data based on The Report of a Settled Population, 1981 conducted by National Bureau of Statistics Economic Planning Board. The sample was basically using stratified two-stage sampling with systematic sampling of Ban or Li as administrative unit. The population represents the whole nation excluding Jeju-do because of budget. The selection of sampling unit and sampling procedure was as follows. 1) Stratify the nation-wide area in 20 sections according to administrative districts. 2) Determine the sample size in each section according to equal proportional rate (1 / 8040) and to about 1,000 households in the sample. 3) Select the 25 sampling units by section according to households proportion. 4) Select the 10 households at random from each Ban or Li according to equal probability proportion as the final sampling unit. Using the procedure, it was sampled 1,000 households for National Nutrition Survey in 1983.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.1
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• pp.25-36
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• 2015

The complex analysis of the pedigree records of Czech Landrace (CLA), Czech Large White-dam line (CLWd), Czech Large White-sire line (CLWs), Duroc (DC), and Pietrain (PN) was performed to determine trends of genetic diversity (GD), and to find the main sources of the GD loss. The total size of the pedigree was 132,365, 391,151, 32,913, 13,299, and 7,160 animals in CLA, CLWd, CLWs, DC, and PN, respectively. Animals born in the years 2011 through 2013 were assumed as the reference population. The average pedigree completeness index for one generation back was 95.9%, 97.4%, 91.2%, 89.8%, and 94.2% for appropriate breeds. Number of ancestors explaining 100% of gene pool was 186, 373, 125, 157, and 37 in CLA, CLWd, CLWs, DC, and PN, respectively. The relative proportion of inbred animals (58%, 58%, 54%, 47%, and 25%), the average inbreeding (2.7%, 1.4%, 2.5%, 3.6%, and 1.3%) and the average co-ancestry (3.1%, 1.6%, 3.3%, 4.2%, and 3.3%) were found over the past decade in analysed breeds. The expected inbreeding under random mating increased during the last 10 years in CLWs and PN and varied from 1.27% to 3.2%. The effective population size computed on the basis of inbreeding was 76, 74, 50, 35, and 83 in 2012 in CLA, CLWd, CLWs, DC, and PN, respectively. The shortest generation interval (1.45) was observed for CLWd in sire to son selection pathway. The longest generation interval obtained PN (1.95) in sire to daughter pathway. The average relative GD loss within last generation interval was 7.05%, 4.70%, 9.81%, 7.47%, and 10.46%, respectively. The relative proportion of GD loss due to genetic drift on total GD loss was 85.04%, 84.51%, 89.46%, 86.19%, and 83.68% in CLA, CLWd, CLWs, DC, and PN, respectively. All breeds were characterized by a high proportion of inbred animals, but the average inbreeding was low. The most vulnerable breeds to loss of GD are DC and PN. Therefore, a breeding program should be more oriented to prevent the increase of GD loss in these breeds.

• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.223-231
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• 2005

A quantitative risk assessment tool was used to provide estimates of the probability that foot-and-mouth (FMD) virus-contaminated, smuggled animal products are fed to susceptible swine in Korea. Sensitivity analyses were conducted to attempt to distinguish between parameter uncertainty and variability, using different assumptions on the effect of cooking at home, the effect of the fresh meat, and the effect of heat treatment at garbage processing facility. The median risk estimate was about 20.1% with a mean value of 27.4%. In a scenario regarding all beef and pork were considered as fresh meat the estimated median risk was 3.4%. The risk was greatly dependent on the survival parameters of the FMD virus during the cooking or heat treatment at garbage processing facility. Uncertainty about the proportion of garbage that is likely contaminated with FMD had a major positive influence on the risk, whereas conversion rate representing the size of a load had a major negative effect. This model was very useful in assessing the risk explored. However, the model also requires enhancements, such as the availability of more accurate data to verify the various assumptions considered such as FMD prevalence in a specific country, proportion of garbage which is recycled as feed, proportion of food discarded as garbage. Other factors including the effect of selection of animals for slaughter, ante- and post-mortem inspection, the domestic distribution of the smuggled products, and susceptible animals other than pigs, are need to be taken into account in the future model development.

• The Journal of Korean Medicine
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• v.44 no.3
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• pp.87-101
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• 2023

Objectives: Many acupuncture points have been suggested for the treatment of Bell's palsy, but information on which acupuncture points are more important in treatment is not provided. This study was conducted to investigate the importance of acupuncture points currently used clinically in Bell's palsy. Methods: By reviewing the full text of 11 books that recorded acupuncture prescriptions from the Qin Dynasty to the Qing Dynasty, the frequency of use of acupuncture points, their meridians, and their location were investigated. Results: The average number of acupuncture points used for local, adjacent and distal points selection was 10.5, 2, 4 respectively. The number of acupuncture points increased from the Qin Dynasty to the Ming Dynasty 《Bojaebang》 and then decreased, but the proportion of local points has been still high. From the Ming Dynasty, ST4, ST6, GV26, and GV24 were mainly have been used as the local points. Except for the GB12, the use of the rest of the acupuncture points gradually decreased in the adjacent points. In the distal acupuncture points, it was summarized to point of lung and large intestine channel until the Ming Dynasty, and LI4 was mainly used in the Qing Dynasty. Yangming meridian has been most often used at the local and distal area except for the adjacent area. Conclusions: In the treatment of facial paralysis, the lower part of the face had the highest proportion among local acupuncture points, and the Yangming had the highest proportion by meridian.

• Journal of Animal Science and Technology
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• v.65 no.3
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• pp.596-610
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• 2023

Focusing high marble deposition, Hanwoo feedlot system uses high-energy diet over the prolonged fattening period. However, due to the individual genetic variation, around 40% of them are graded into inferior quality grades (QG), despite they utilized the same resources. Therefore, focusing on development of a nutrigenomic based precision management model, this study was to evaluated the response to the divergent selection on genetic merit for marbling score (MS), under different dietary total digestible nutrient (TDN) levels. Total of 111 calves were genotyped and initially grouped according to estimated breeding value (high and low) for marbling score (MS-EBV). Subsequently, managed under two levels of feed TDN%, over the calf period, early, middle, and final fattening periods following 2 × 2 factorial arrangement. Carcasses were evaluated for MS, Back fat thickness (BFT) and Korean beef quality grading standard. As the direct response to the selection was significant, the results confirmed the importance of initial genetic grouping of Hanwoo steers for MS-EBV. However, dietary TDN level did not show an effect (p > 0.05) on the MS. Furthermore, no genetic-by-nutrition interaction for MS (p > 0.05) was also observed. The present results showed no correlation response on BFT (p > 0.05), which indicates that the selection based on MS-EBV can be used to enhance the MS without undesirable effect on BFT. Ultimate turnover of the Hanwoo feedlot operation is primarily determined by the QGs. The present model shows that the initial grouping for MS-EBV increased the proportion of carcasses graded for higher QGs (QG1⁺⁺ and QG1⁺) by approximately 20%. Moreover, there appear to be a potential to increase the proportion of QG 1⁺⁺ animals among the high-genetic group by further increasing the dietary energy content. Overall, this precision management strategy suggests the importance of adopting an MS based initial genetic grouping system for Hanwoo steers with a subsequent divergent management based on dietary energy level.

• Journal of Korean Library and Information Science Society
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• v.45 no.4
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• pp.45-65
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• 2014

The purpose of this research is to examine the characteristics and current status of OASIS, a web archive, developed and operated by the National Library of Korea. From December 2013 to November 2014, an analysis of a numerical growth and subject distribution of 55,581 websites archived at OASIS shows many problems in quality, including an overwhelming proportion of 'Social Science' and its subclass 'Politics', consequential lack of balance in subject distribution, lack of authority or scholarly value of some contents, unclear application of selection criteria for personal creators/publishers, and inaccurate and overlapping statistics. Despite an impressive growth in quantity, immediate improvement of selection policies and quality control is needed.

• Journal of the Korean Society for Library and Information Science
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• v.8
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• pp.233-263
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• 1981

The purpose of this study is to bring out the most reasonable and feasible evaluation methods of research library collection in Korea. At the very outset, writer tried to define the purpose and the necessity of collection evaluation. Writer described a collection evaluation is to gain the data for decision making on selection policy, weeding and storage project, and explained it is one of the procedures of a collection development system operation of being explained as repeated three procedures through a collection development plan, an implimentation of the set plan(selection process) and a collection evaluation. Writer also pointed out the fact many libraries in Korea are apt to by pass or overlook this important process. Writer then defined the criteria of a collection evaluation as the measurement of the proportion of library holding's capability to meet users' demands and that of the degree of total collection's utilization. Writer introduced and analysed seven existing collection evaluation methods and concluded the method by a survey of users' needs and opinion and the method by a circulation survey are the most feasible and reasonable methods that can be applied. Writer also added that using above two evaluation methods together can enhance the effectiveness of collection evaluation.