• 대한기관식도과학회지
• /
• 제4권2호
• /
• pp.182-187
• /
• 1998

Platelet activating factor (PAP) has been known as implicating as one of potent inflammatory mediators and reported 0 be involved in inflammation and allergy. PAF induces ciliary dysfunction and epithelial damage of human paranasal sinus mucosa in vitro. However, several recent papers have reported that PAF may not readily damage the airway epithelium. The aim of this study was to investigate the ultrastructural evidence to elucidate the pathogenesis of epithelial damage induced by PAF. Sixteen $\mu\textrm{g}$ g of PAF was applied into the maxillary sinuses of 6 rabbits. Rabbits were divided into 2 subgroups along with time interval at 1st and 3rd experimental day, and sinus mucosae were taken for the histopathologic study using electron microscopy. At 1st day, epithelial cells showed no ultrastructural change. Ultrastructures of the cilia were well preserved. Subepithelial space showed no evidence of the infiltration of inflammatory cells. Intravascular platelet aggregation and swelling of endothelial cells were evident. At 3rd day, epithelial cells showed vacuolar degeneration. Fusion of cilia forming giant cilia and focal loss of cilia were evident. Eosinophils were infiltrated in subepithelial and intraepithelial space. Swelling of endothelial cells, and migration of inflammatory cells into the connective tissue were evident. This study implies that epithelial damage induced by PAF may be secondary to the cytotoxicity of mobilized eosinophils rather than direct cytotoxicity of PAF.

• 한국방재학회:학술대회논문집
• /
• 한국방재학회 2008년도 정기총회 및 학술발표대회
• /
• pp.735-738
• /
• 2008

Various characteristics of creek were not considered in designing creek for a long time. As result of that, a lot of reverse functions have been present in creek. In this study, a presentation of creek damage was investigated and differences river form creek design standards were analyzed. The damage of creeks accounts for 37.3 percent of total damage of rivers over the last 6 years. Besides, government should spend more money in restoring creeks. Considering that maintenance rate of domestic creeks is 37 %, counterplan should be prepared to prevent the damage of creeks. There are many kinds of causes in destroyed creek round. Specially, most damage was secondary that was caused by increase of flood elevation according to decrease in conveyance, local scour around structures, and failures because of inappropriate structures such as bridge, culvert, crossbeam, and drop in creek. These destroy types are in bend area. However, current creek design standards do not suggest solutions to prevent damages. Currently, there are no standards for bridge, and appropriate hight and width of culvert. Standards for crossbeam and drop could not reflect characteristics of creek. Therefore, it is need to improve the creek design standards for appropriate design and construction. That could improve flood control and prevention of creeks.

• 한국농촌건축학회논문집
• /
• 제21권3호
• /
• pp.25-32
• /
• 2019

This study is to derive the types of displacement and damage that occur in wooden architecture cultural assets. Although the wooden architectural cultural assets are being repaired through continuous maintenance, secondary problems frequently occur. This is because the root cause of the problem has yet to be solved. The types of displacement and damage that occur in the wooden architecture cultural asset are classified into three parts: the foundation section, the gagu section, and the roof section. In turn, the three main factors that lead to displacement and damages are the structures' load impact, the durability deterioration, and the imbalance. Load impact is a phenomenon in which the member is subjected to a load that causes deformation or cracks. Durability decline is a natural phenomenon that reduces the performance of lumber as a result of check shake, termite damage, and decay. The imbalance is a condition in which the lumber is twisted and the force balance is lost, due to either drying shrinkage or displacement of the gagu section.

• 한국안전학회지
• /
• 제37권4호
• /
• pp.92-100
• /
• 2022

Of the Korean military's 3,959 ammunition depots, 1,007 - more than 25% - violate safety requirements for distance and equipment. There is a risk of explosion in old depots that are vulnerable to various interior and exterior accidents. This paper examines 10 scenarios, with varying values for ammunition amount and safety distance. The study calculated the overpressure that can be applied to risk-exposure objects, based on the safety distance; expected damage was predicted using constructed spatial information from 3D explosion simulations. The simulations confirmed that explosion overpressure increased the most when the safety distance violation rate increased from 80% to 90%. It also confirmed that secondary damage such as fire and explosion can cause casualties and property damage when the violation rate is 60% or higher. The results show that building collapse becomes a risk with a violation rate of 70% or higher. We conclude that taking ammunition depot safety distance violation into account when planning military facilities and their land utilization could better protect life and property.

• 한국멀티미디어학회논문지
• /
• 제17권9호
• /
• pp.1098-1103
• /
• 2014

Smartphone is very much ingrained into our lives and it has propagated rapidly. With the growing expansion of smartphone, the number of lost smartphones has proliferated all the while. Unlike common personal belongings, smartphone is a high-priced goods and has personal information. In case it gets lost or stolen, it will cause monetary damage as well as secondary damage of personal information leaks. To lesson the damage, diverse applications that prevent the loss of a smartphone have been developed. But existing applications place emphasis on providing countermeasures that tracks the missing smartphones. Therefore, this paper describes the design and implementation of a smartphone application which provides precautionary functions to prevent the loss of a smartphone and countermeasures to track the missing smartphone. The implemented application prevents the loss of a smartphone using satefy zone and movement detection. In the event we lose a smartphone, it helps us recover a lost property using location tracking and remote control functions quickly and efficiently.

• 미생물학회지
• /
• 제26권2호
• /
• pp.113-121
• /
• 1988

Ozone, an atmospheric pollutant, can damage similar UV and X-rays DNA and its components. It is possible then that the KNA damage produced by this gas are similar, to some extent, to those of radiations and that they could be repaired by the same DNA repair mechanisms. It has been observed in Escherichia coli that radiosensitive strains such as lex A, rec A and pol A, all deficient to some extent for DNA repair, are more sensitive to ozone than a wild type strain. We have thendetermined the ozone resistance and host-cell reactivation of ozone-damaged T3 phages for the E. coli double mutants pol A, lex A, uvr B, lex A, uvr A, rec A and rec A lox A. According to the results, the DNA polymerase 1 plays a key role in ozone resistance and Type 11 mechanism and/or shory patch excision repair are the most important for it. The interactions between the different DNA repair mechanisms are secondary. There is a strong correlation between ozone resistance and the capacity to reactivate T3 phages damaged by ozone.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 2011년도 한국우주과학회보 제20권1호
• /
• pp.28.1-28.1
• /
• 2011

Radiation-induced displacement damage which has caused the increase of the dark current in the focal plane adopted in the Ozone Monitoring Instrument (OMI) was studied in regards of the primary protons and the secondaries generated by the protons in the orbit. By using the Monte Carlo N-Particle Transport Code System (MCNPX) version 2.4.0 along with the Stopping and Range of Ions in Matter version 2010 (SRIM2010), effects of the primary protons as well as secondary particles including neutron, electron, and photon were investigated. After their doses and fluxes that reached onto the charge-coupled device (CCD) were examined, displacement damage induced by major sources was presented.

• Earthquakes and Structures
• /
• 제9권1호
• /
• pp.257-279
• /
• 2015

The primary objective of this study is to summarize results from previous experimental tests on laboratory specimens of RC/steel frames with masonry infills, in order to develop fragility functions that permit the estimation of damage in typical non-structural components of RC frame buildings, as a function of attained peak interstory drift. The secondary objective is to derive loss functions for such non-structural components, which provide information on the probability of experiencing a certain level of monetary loss when a given damage state is attained. Fragility curves and loss function developed in this study can be directly used within the FEMA P-58 framework for the seismic performance assessment of RC frame buildings with masonry infills.

• International Journal of Safety
• /
• 제9권1호
• /
• pp.12-20
• /
• 2010

In this study, a series of random field test and dynamic analysis in the time domain were carried out in order to find in the reason of fatigue damage of the main and the secondary members in the 3-span continuous steel plate girder railway bridge being under in service over 60 years. From the measured and the analyzed results, the stress distribution patterns were investigated for the members with fatigue damage. In addition, global and local numerical stress analysis was performed for the members damaged severely by corrosion, to estimate variation of the distribution by corrosion. Finally, a reasonable cut-off ratio in the steel plate railway bridge will be proposed by analyzing the equivalent stress ranges according the ratio.

• Safety and Health at Work
• /
• 제8권1호
• /
• pp.42-48
• /
• 2017

Background: As one of the most frequently occurring accidents in a chemical plant, a fire accident may occur at any place where transfer or handling of combustible materials is routinely performed. Methods: In particular, a jet fire incident in a chemical plant operated under high pressure may bring severe damage. To review this event numerically, Computational Fluid Dynamics methodology was used to simulate a jet fire at a pipe of a compressor under high pressure. Results: For jet fire simulation, the Kemeleon FireEx Code was used, and results of this simulation showed that a structure and installations located within the shelter of a compressor received serious damage. Conclusion: The results confirmed that a jet fire may create a domino effect that could cause an accident aside from the secondary chemical accident.