• Title/Summary/Keyword: Secondary analysis

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Effect of intravenous ascorbic acid administration on fatigue after laparoscopic myomectomy: A randomized, double-blind, placebo-controlled trial (복강경 자궁근종절제술을 받은 여성에서 정맥 내 아스코르브산 투여가 피로에 미치는 영향: 무작위 배정 양측맹검 위약대조 임상시험)

  • Hwang, Woo Yeon;Kim, Kidong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.434-439
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    • 2021
  • We assessed the effects of intravenous (IV) ascorbic acid administration on fatigue in women undergoing laparoscopic myomectomy. We analyzed the secondary endpoint results of a randomized, double-blind, placebo-controlled trial. Fifty patients undergoing laparoscopic myomectomy received IV ascorbic acid (2g) or placebo (randomly 1:1 ratio) intravenously during surgery. On day 2 post-surgery, we measured the level of fatigue using the Brief Fatigue Inventory-Korean version. Forty-five women (experimental arm 23, control arm 22) were eligible for analysis after 5 women (experimental arm 2, control arm 3) were excluded due to withdrawal of consent, cancellation of surgery or non-measurement of the endpoints. The baseline and operative characteristics were similar between arms and the global fatigue score of the experimental arm (4.56 ± 2.63) was not significantly different from that of the control arm (5.21 ± 2.02, P = 0.351). However, the fatigue score of the experimental arm tended to be lower than that of the control arm in most domains. IV ascorbic acid administration did not significantly reduce the level of fatigue in women undergoing laparoscopic myomectomy as compared to placebo. More research is needed to better understand the effects of ascorbic acid on fatigue in surgical patients.

Comparing Inhaler Use Technique Based on Inhaler Type in Elderly Patients with Respiratory Disease

  • Lee, Ha Youn;Song, Jin Hwa;Won, Ha-Kyeong;Park, Yeonkyung;Chung, Keun Bum;Lim, Hyo-Jeong;Ahn, Young Mee;Lee, Byoung Jun
    • Tuberculosis and Respiratory Diseases
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    • v.84 no.1
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    • pp.46-54
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    • 2021
  • Background: The aim of this study was to investigate inhaler device handling in elderly patients. Inhaler devices with respect to misuse and error correction were also compared. Methods: Inhaler use technique was assessed using standardized checklists at the first visit and 3-month follow-up visit after retraining. The primary outcome was difference in the acceptable use ratio among inhaler devices. Secondary outcomes included differences in error correction, the most common step of misuse, and factors affecting the accuracy of inhaler use. Results: A total of 251 patients (mean age, 76.4 years) were included. The handling of 320 devices was assessed in the study. All patients had been trained before. However, only 24.7% of them used inhalers correctly. Proportions of acceptable use for Evohaler, Respimat, Turbuhaler, Ellipta, and Breezhaler/Handihaler were 38.7%, 50.0%, 61.4%, 60.8%, and 43.2%, respectively (p=0.026). At the second visit, the acceptable use ratio had increased. There were no significant differences among inhaler types (Evohaler, 63.9%; Respimat, 86.1%; Turbuhaler, 74.3%; Ellipta, 64.6%; and Breezhaler/Handihaler, 65.3% [p=0.129]). In multivariate analysis, body mass index, Turbuhaler, and Ellipta showed positive correlations with acceptable use of inhalers, whereas Chronic Obstructive Pulmonary Disease Assessment Test score showed a negative correlation. Conclusion: Although new inhalers have been developed, the accuracy of inhaler use remains low. Elderly patients showed more errors when using pressurized metered-dose inhalers than using dry powder inhalers and soft-mist inhalers. However, there were no significant differences in misuse among inhaler devices after individual training. Results of this study suggests that repeat training is more important than inhaler type.

Intravenous Fluid Selection for Unruptured Intracranial Aneurysm Clipping : Balanced Crystalloid versus Normal Saline

  • Kang, Jian;Song, Young Joo;Jeon, Sujeong;Lee, Junghwa;Lee, Eunsook;Lee, Ju-Yeun;Lee, Euni;Bang, Jae Seung;Lee, Si Un;Han, Moon-Ku;Oh, Chang Wan;Kim, Tackeun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.4
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    • pp.534-542
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    • 2021
  • Objective : While balanced crystalloid (BC) could be a relevant fluid regimen with buffer system compared with normal saline (NS), there have been no studies on the optimal fluid for surgery of an unruptured intracranial aneurysm (UIA). This study aimed to compare the effects of fluid regimens between NS and BC on the metabolic and clinical outcomes of patients who underwent surgery for UIA. Methods : This study was designed as a propensity score matched retrospective comparative study and included adult patients who underwent UIA clipping. Patient groups were categorized as NS and BC groups based on the types of pre-operative fluid and the amount of fluid administered during surgery. The primary outcomes were defined as electrolyte imbalance and acidosis immediately after surgery. The secondary outcomes were the length of stay in the intensive care unit (ICU) and duration from the end of the operation to extubation. Results : A total of 586 patients were enrolled in this study, with each of 293 patients assigned to the NS and BC groups, respectively. Immediately after surgery, serum chloride levels were significantly higher in the NS group. Compared to the NS group, the BC group had lower incidence rates of acidemia (6.5% vs. 11.6%, p=0.043) and metabolic acidosis (0.7% vs. 4.4%, p=0.007). As compared to NS group, BC group had significantly shorter duration from the end of the operation to extubation (250±824 vs. 122±372 minutes, p=0.016) and length of stay in ICU (1.37±1.11 vs. 1.12±0.61 days, p=0.001). Throughout multivariable analysis, use of BC was found to be significant factor for favorable post-operative results. Conclusion : This study showed that the patients who received BC during UIA clipping had lower incidence of metabolic acidosis, earlier extubation and shorter ICU stay compared to those who received NS. Therefore, using BC as a peri-operative fluid can be recommended for patients who undergo surgery for UIA.

Frailty and its Related Factors in the Vulnerable Elderly Woman by Urinary Incontinence (지역사회 거주 여성노인의 요실금 유무에 따른 허약정도와 허약 영향요인)

  • Park, Jin Kyoung
    • 한국노년학
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    • v.37 no.4
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    • pp.893-907
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    • 2017
  • This study aimed to investigate factors affecting frailty by urinary incontinence groups among the vulnerable elderly woman in Korea. In this secondary analysis, data were collected from records for 3,251 elders registered in the Visiting Health Management program of Public Health Centers in 2012. body mass index, waist circumference, timed up & go, depression, self rated helath, walking exercise, flexibility exercise, strengh exercise and frailty were assessed. Data were analyzed using $x^2$-test, t-test, ANOVA, Pearson's correlation and stepwise regression to determine the associated factors of frailty by urinary incontinence. Depression, walking exercise, timed up & go and age were found to be factors significantly associated with frailty among the elders with incontinence(F=38.321, p<.001). Age, depression, walking exercise, self rated health and tined up & go were found to be factors associated with frailty in the elders without incontinence(F=265.666 p<.001). The findings show that frailty of elders and associated factors were different by urinary incontinence, and common factors affecting frailty were depression, walking exercise, timed up & go, age. Thus, these factors should be considered in the development of intervention program for care and prevention of frailty and program should be modified according to urinary incontinence.

The Effects of Quality of Life in the Elderly's Health Condition (노인의 건강상태가 삶의 질에 미치는 영향)

  • Lee, Dong-Ho
    • 한국노년학
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    • v.30 no.1
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    • pp.93-108
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    • 2010
  • This study conducted a secondary analysis by using original data of performed by Korea Institute for Health and Social Affairs to determine factors affecting health-related quality of life for the elderly aged over 65 years living in Korea. The survey was conducted in 2005 and it evaluated totally 34,152 cases. Among them 3074 cases investigating the elderly aged over 65 years were selected for this study and finally 2036 cases were included in it by excluding cases with no answer or a wrong answer. The results were as follows. In the illness days, the average of the whole subjects was 11.05 days and it was longer when subjects were female and older, had lower educational background and lower family income, did not have spouses and jobs and were covered by medical aid as medical security. In the years of activity restriction, the average of the total subjects was 3.48 years and it was increased when they were older, had lower educational background and lower family income, did not have spouses, lived in detached houses and were covered by medical aid as medical security. Subjective health condition of the total subjects was 2.64 points out of 5 points in average. The scores were higher when subjects were male, younger, had better educational background, spouses, jobs and more family income, lived in multi-family living houses and were covered by corporate insurance as medical security. The average of total quality of life of the subjects was 2.61 points out of 3 points and it was found to be higher when subjects were male, younger, had better educational background, spouses, jobs and more family income and were covered by corporate insurance as medical security. It was decreased with higher illness days, higher years of activity restriction and lower subjective health condition. For the effects of the factors related to quality of life, subjective health condition showed the largest influence.

The Effect of Welfare Status on Welfare Attitudes: Focusing on the Moderating Effect of Trust in Government (복지지위가 복지인식에 미치는 영향: 정부신뢰의 조절효과를 중심으로)

  • Choi, Go Eun
    • 한국사회정책
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    • v.23 no.1
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    • pp.125-150
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    • 2016
  • This study was carried out to empirically analyze the hypothesis that the impact of the welfare status on the welfare attitudes is moderated by each individual's level of confidence in government. To do this, this study focused on the welfare status known as the significant predictors of welfare attitudes and measured the welfare status as a gap between 'welfare contribute' and 'welfare benefit' in a single dimension, which is defined as 'material sacrifice'. Also, this study examined the main effect of material sacrifice and trust in government on the welfare attitudes and moderating effect of trust in government on relationship between material sacrifice and welfare attitudes. This study was performed with secondary data from 8th year of "2013 Korea Welfare Panel Study". Hypothesis of this study were verified using hierarchical multiple regression analysis. The major findings of this study are summarized as follow. 'Material sacrifice' was found to be negatively associated with the welfare attitudes. However, as the confidence in which social policies will be carried out competently by government increases, it was confirmed that the negative effect of material sacrifice on the welfare attitudes was moderated. It suggests that self-material interests associated with welfare could be moderated by beliefs and expectations about the government's functions, which means that expanding the reliance on the social policy is an important task in order to lead a social consensus for the welfare expansion.

Teaching Democracy in Indonesian Civic Education Textbook (인도네시아 시민윤리교육 교과서에서의 민주주의 교육)

  • KIM, Hyun Kyoung
    • The Southeast Asian review
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    • v.27 no.3
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    • pp.1-47
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    • 2017
  • This paper examines how democracy is being taught in secondary school level of Indonesian civic education. For this purpose, this study analyses the textbook contents concerning democracy. First, this study sets the freedom, the right, the unity and the stability as key words and analyzes the characteristic of describing democracy by looking at how each keyword is explained in the textbook. The result of analysis shows that democracy of Indonesia can be described as "Pancasila democracy" and textbooks have tendency to relatively emphasize 'the unity', and 'the stability' by differentiating themselves from "liberal democracy" and "liberalism." The freedom in textbook can be interpreted in the context of organic-statism that state and interests of state have the ascendancy over individuals. This viewpoint is based on the historical contexts of Indonesia. However, when textbook describes about Indonesian democracy and its values, they deal with contents of democratic principles, "the freedom of opposition", "the negative freedom", and natural rights. And the study interprets the existence of the two contrasting concepts - relative emphasis on the unity of state and the statement about the importance of individual rights and the freedom - in the textbook as a logical tension in transitional process of traditional organic-statism. Second, the study examines educational contents in accordance with the method of description in textbook. It has been found that there are logical tension and fallacy in describing the principle of fundamental concepts and applicate that concepts into Indonesia case. Also, when describing Marsinah and Munir case, there are some parts distorted and overlooked the facts. On the other hand, the gaps between the explanation in textbook and reality can be pointed out. This study which examined textbook and contents of the rights of the individual is an introductory study on textbook, education and democracy for development of Indonesia and their education.

Residue and risk assessment of veterinary antibiotics in manure-based composts and agricultural soils (가축분뇨 유래 퇴비 및 농경지 중 축산용 항생제의 잔류 및 위해성 평가)

  • Paik, Min-Kyoung;Ryu, Song-Hee;Kim, Sung-Chul;Hong, Young-Kyu;Kim, Jin-Wook;Kim, Jeong-Gyu;Kwon, Oh-Kyung
    • Journal of Applied Biological Chemistry
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    • v.64 no.2
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    • pp.177-184
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    • 2021
  • While veterinary antibiotics are used only in a part of the dose administered, the rest are excreted as urine or feces. Residual antibiotics enter the adjacent agricultural environments by spraying manure-based composts on farmlands and lead to secondary pollution. Therefore, it is necessary to develop the technique for post management such as regulatory levels of antibiotics in the agricultural environments. This study was conducted to compare by different matrices the amount of residual antibiotics such as tetracyclines and sulfonamides, which are known to be frequently used in Korea and to practice risk assessment by different antibiotics in soils before and after application of composts. Pre-treatment with modified typical method using buffer and solid phase extraction showed the recovery of composts and soils was more than 70% at ppb level and the limits of detection were 0.13-0.46 and 0.05-0.25 ㎍/kg, respectively. Analysis of manure-based composts revealed concentrations from 5.38 to 196.0 ㎍/kg for tetracyclines, from below the detection of limit (BDL) to 259.0 ㎍/kg for sulfonamides. In case of agricultural soils, residual concentrations of selected veterinary antibiotics were ranged 0.30-53.3 ㎍/kg, BDL-4.16 ㎍/kg respectively and the concentration level of tetracyclines, which had higher soil distribution coefficient (Kd) values, was higher than that of sulfonamides. There was a difference in human risk assessment by different antibiotics in soil before and after application of composts. But, it was indicated that detection values of all of 5 antibiotics were very safe on the basis that Hazard Quotient was safe below 1.

A Study on a Method to Reduce Marine Pollution Accidents through Tugboat Grounding - Focusing on an Experiment of Indicating the Location of Stranded Accidents on GPS Plotters - (예인선 좌초에 의한 해양오염사고 감소방안에 관한 연구 - GPS 플로터에 좌초사고 위치표시 실험을 중점으로 -)

  • Kim, Do-Hoon;Kang, Woo-Kyung
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.1
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    • pp.29-37
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    • 2021
  • In the event of a marine pollution accident, Korea, which is bordered by the sea on three sides, would suffer tremendous damage. According to an analysis of marine pollution accidents in Korea, most pollutants were small fishing boats and tugboats. In particular, urgent safety measures are required due to the high incidence of marine pollution accidents caused by stranded tugboats. This study aims to decrease secondary marine pollution accidents by preparing measures to prevent accidents by stranded tugboats, the main source of pollution accidents. To this end an experiment was conducted to mark 63 locations where stranded accidents have occurred on the GPS plotters of 61 tugboats operating in Boryeong sea area. Its effectiveness was then investigated. The result showed that there was no stranded accident by the subject ship during the 20-month experiment period. As a result of survey of the captains, 36 out of 40 respondents (90%) stated that the experiment was significantly helpful in ensuring safe navigation, thus confirming its effectiveness. Various measures were proposed to prevent stranded accidents, including providing information to manufacturers and users by marking the location of grounded accidents on GPS plotters and posting the location information of unknown reefs on the official website of institution Korea Hydrographic and Oceanographic Agency.

The Consumption Patterns of Korean Native Chicken (식품 소비 성향에 따른 토종닭 구매요인 분석)

  • Park, Seoyoung;Kim, Nayeong;Choi, Suhyun;Moon, Junghoon
    • Korean Journal of Poultry Science
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    • v.47 no.4
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    • pp.247-254
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    • 2020
  • This study examined how consumer choices (i.e., selecting food safety certified products, health-related products, and familiar brands) affect the purchase of Korean native chicken (KNC) and the demographics that influence KNC purchases using secondary consumer panel data from the Rural Development Administration of Korea. The grocery purchase data from 654 Korean households between 2017 and 2019 were used; the propensity for food safety certified products was measured by the purchasing frequency of Good Agricultural Practice (GAP) and Hazard Analysis and Critical Control Point (HACCP) products, and the propensity for health-related products was measured by the purchasing frequency of home meal replacement (HMR) and hedonic products. The propensity to purchase familiar brands was measured using a questionnaire. Logistic regression was used to examine the determinants of the KNC purchase experience, and multiple linear regression was used to determine the factors that influenced the KNC purchase frequency. The results showed that unemployed women purchased more safety certified products, health-related products, familiar brands, and KNC. These findings suggest that targeting consumers with differential marketing strategies may help promote KNC consumption. This study identified factors that influence KNC purchases, which is important for understanding consumer behavior and revitalizing the market.