• Health Policy and Management
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• v.7 no.2
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• pp.89-108
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• 1997

The purpose of this study is to investigate drug information sources which influence physician's prescriptions, and to compare the differences of drugh information sources between private practitioners and hospital physicians. In addition, the ultimate goal of this study is to provide better quality of drug information for both groups of physicians through the professional drug information system. 264 physicians, including general practitioners and all types of specialists who were working in hospitals and private clinics in Taejon and Chungnam area, participated in this study which was conducted by mail. The results are summarized as follows ; 1. Both physician groups received drug informations mainly from medical journals, but there were differences in secondary sources of drug information. Namely, hospital physicians got drug information from annual meetings and textbooks, and private practitioners got it from detail men and colleagues. 2. Drug effect was the first consideration for drug selection in both physician groups. But, in the 2nd consideration, private practitioners concerned about the price, insurance and rebates, but hospital physicians were not. 3. Only 9.2% of the private practitioners satisfied with the sufficiency of drug information, whereas 22.0% of hospital physicians satisfied with it. The most insufficient area of information was drug interaction in both groups and 91.9% of the physicians suggested that a professional drug information system should be introduced. 4. Both physician groups had contacted with detail men frequently. However, it was rare for them to contact with a pharmacist. This phenomenon was more severe in the case of private practitioners. 5. Neither physician groups knew very much about drug informatio centers. However, they would be willig to participate if a professional drug information system were established. Also, they indicated that the information most required was drug interaction.

• Journal of Preventive Medicine and Public Health
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• v.57 no.4
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• pp.307-318
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• 2024

Objectives: Effective data collection and surveillance of epidemiological trends are essential in confronting the growing challenges associated with substance use (SU), especially in light of emerging trends and underreporting of cases. However, research and data are scarce regarding SU and substance use disorder (SUD) in Korea. Methods: We conducted a scoping review to identify data sources and surveillance methods used in SU research in Korea up to December 2023. This review was complemented by semi-structured consultations with experts in this area in Korea, whose feedback led to revisions of previously identified data sources and assessments. Results: Our review identified 32 publications conducting secondary analyses on existing data to examine the epidemiology of SU and SUD in Korea. Of these, 14 studies utilized clinical databases to explore the prescription patterns of addictive substances, particularly opioids. Eleven data sources showed promise for advancing SU research; however, they face substantial limitations, including a lack of available data, missing data, the absence of key variables, the exclusion of marginalized populations not captured within the clinical system, and complexities in matching individual-level data across time points and datasets. Conclusions: Current surveillance methods for SU in Korea face considerable challenges in accessibility, usability, and standardization. Moreover, existing data repositories may fail to capture information on populations not served by clinical or judicial systems. To systematically improve surveillance approaches, it is necessary to develop a robust and nationally representative survey, refine the use of existing clinical data, and ensure the availability of data on treatment facilities.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.3
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• pp.302-313
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• 2008

The purposes of this study are to investigate the concentration levels of fine particles, so called PM$_{2.5}$, to identify the affecting sources, and to estimate quantitatively the source contributions of PM$_{2.5}$. Ambient air sampling was seasonally carried out at two sites in Pohang(a residential and an industrial area) during the period of March to December 2003. PM$_{2.5}$ samples were collected by high volume air samplers with a PM$_{10}$ Inlet and an impactor for particle size segregation, and then determined by gravimetric method. The chemical species associated with PM$_{2.5}$ were analyzed by inductively coupled plasma spectrophotometery(ICP) and ion chromatography(IC). The results showed that the most significant season for PM$_{2.5}$ mass concentrations appeared to be spring, followed by winter, fall, and summer. The annual mean concentrations of PM$_{2.5}$ were 36.6 $\mu$g/m$^3$ in the industrial and 30.6 $\mu$g/m$^3$ in the residential area, respectively. The major components associated with PM$_{2.5}$ were the secondary aerosols such as nitrates and sulfates, which were respectively 4.2 and 8.6 $\mu$g/m$^3$ in the industrial area and 3.7 and 6.9 $\mu$g/m$^3$ in the residential area. The concentrations of chemical component in relation to natural emission sources such as Al, Ca, Mg, K were generally higher at both sampling sites than other sources. However, the concentrations of Fe, Mn, Cr in the industrial area were higher than those in the residential area. Based on the principal component analysis and stepwise multiple linear regression analysis for both areas, it was found that soil/road dust and secondary aerosols are the most significant factors affecting the variations of PM$_{2.5}$ in the ambient air of Pohang. The source apportionments of PM$_{2.5}$ were conducted by chemical mass balance(CMB) modeling. The contributions of PM$_{2.5}$ emission sources were estimated using the CMB8.0 receptor model, resulting that soil/road dust was the major contributor to PM$_{2.5}$, followed by secondary aerosols, vehicle emissions, marine aerosols, metallurgy industry. Finally, the application and its limitations of chemical mass balance modeling for PM$_{2.5}$ was discussed.

• Food Science and Preservation
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• v.21 no.5
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• pp.601-608
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• 2014

To determine the optimal shelf life for maintaining the high quality of kohlrabi, the changes in the physiological and secondary metabolites of kohlrabi stems during storage were investigated. The results showed that the kohlrabi maintained its marketable quality for two weeks at room temperature and for two months in cold storage ($4^{\circ}C$). Interestingly, the total phenol and flavonoid contents sharply declined along with the quality deterioration after two-week storage at room temperature. Moreover, insignificant changes in these compounds were observed for two months during the cold storage. The secondary metabolites of the kohlrabi were also influenced by its storage condition. The total phenol and total flavonoid contents of the kohlrabi significantly increased with the storage periods at low temperature, and significantly decreased with the storage periods at room temperature. In terms of the packaging, no significant difference in the total phenol content of the kohlrabi was found between the packaged and non-packaged types of storage. However, the flavonoid content of the packaged kohlrabi was higher than that of the non-packaged kohlrabi at the end of their storage. The content of glucosinolates, an anti-cancer ingredient was maintained during the storage, so the vegetables remained good sources of these compounds when stored in cold storage even for a long period. This study showed a close correlation between the secondary metabolites and the change in the quality of kohlrabi during storage. The results also suggested that secondary metabolites such as phenolics can be considered quality indicators of the shelf life of kohlrabi.

• Journal of Environmental Science International
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• v.27 no.4
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• pp.241-250
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• 2018

The objective of this study was to estimate air quality trends in the study area by surveying monthly and seasonal concentration trends. To do this, the mass concentration of $PM_{10}$ samples and the metals, ions, and total carbon in the $PM_{10}$ were analyzed. The mean concentration of $PM_{10}$ was $33.9{\mu}g/m^3$. The composition of $PM_{10}$ was 39.2% ionic species, 5.1% metallic species, and 26.6% carbonic species (EC and OC). Ionic species, especially sulfate, ammonium, and nitrate, were the most abundant in the $PM_{10}$ and had a high correlation coefficient with $PM_{10}$. Seasonal variation of $PM_{10}$ showed a similar pattern to those of ionic and metallic species. with high concentration during the winter and spring seasons. $PM_{10}$ showed high correlation with the ionic species $NO_3{^-}$ and $NH_4{^+}$. In addition, $NH_4{^+}$ was highly correlated with $SO{_4}^{2-}$ and $NO_3{^-}$. We obtained four factors through factor analysis and determined the pollution sources using the United States Environmental Protection Agency(U.S. EPA) pollution profile. The first factor accounted for 51.1% of $PM_{10}$ from complex sources, that is, soil, motor vehicles, and secondary particles: the second factor indicated marine sources; the third factor, industry-related sources; and the last factor, heating-related sources. However, the pollution profile used in this study may be somewhat different from the actual situation in Korea because it was from US EPA. Therefore, to more accurately estimate the pollutants present, it is necessary to create a pollution profile for Korea.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.7
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• pp.1087-1094
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• 2003

The piston slap phenomenon occurs when the piston collides with the internal wall of the cylinder. Impact force caused by piston slap is one of the major mechanical noise sources in reciprocating compressors. In response to public demand, strict regulations are increasingly being imposed on the allowable noise level which is caused mostly by household electric appliances. In this paper, forces acting on piston by considering the dynamic behavior of suction and discharge valves are analytically calculated and the piston slap caused by the piston secondary motion is investigated by the finite element method.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.185-188
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• 2001

We have developed a synthetic method for dTDP-4-keto-6-deoxy-D-glucose with four enzyme system. We have used crude extracts from cultures of Escherichia coli BL21 strains harboring plasmids containing different sources. dTDP-4-keto-6-deoxy-D-glucose was synthesized by the combination of thymidine-monophosphate kinase, acetate kinase, dTDP-glucose synthase and dTDP-D-glucose 4,6-dehydratase in a batch system, starting the reaction with dTMP. The enzymatic synthesis strategy allowed a dTMP conversion with a 95%.

• Journal of Microbiology and Biotechnology
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• v.11 no.1
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• pp.13-16
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• 2001

Maltose and soluble starch were used as secondary sources of carbon for glucoamylase production by Aspergillus awamori in solid state fermentation. During batch cultivation, maltose above 2.5%(w/w) repressed glucoamylase production, but, by adding either 2.5% (w/w) maltose or 1.25% (w/w) soluble starch to fed-batch cultivations, glucoamylase activity was increased by 15% and 170% over standard medium, respectively. The data showed that maltose is a weak inducer of glucoamylase production in solid stat fermentation.

• Bulletin of the Korean Space Science Society
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• 2011.04a
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• pp.28.1-28.1
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• 2011

Radiation-induced displacement damage which has caused the increase of the dark current in the focal plane adopted in the Ozone Monitoring Instrument (OMI) was studied in regards of the primary protons and the secondaries generated by the protons in the orbit. By using the Monte Carlo N-Particle Transport Code System (MCNPX) version 2.4.0 along with the Stopping and Range of Ions in Matter version 2010 (SRIM2010), effects of the primary protons as well as secondary particles including neutron, electron, and photon were investigated. After their doses and fluxes that reached onto the charge-coupled device (CCD) were examined, displacement damage induced by major sources was presented.

• Journal of Electrical Engineering and Technology
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• v.4 no.2
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• pp.194-200
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• 2009

In this paper, the cooperative control scheme of micro sources and an ESS (Energy Storage System) during islanded operation is presented and evaluated by a simulation study. The ESS handles the frequency and voltage as a primary control. Then, the secondary regulation control returns the cur-rent power output of ESS into a pre-planned value. The simulation's results show that the proposed co-operative control scheme can regulate the frequency and voltage and reduce the consumption of the stored energy of ESS.