• Title/Summary/Keyword: Secondary $SO{_4}^{2-}$ and $NO_3{^-}$

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A retrospective clinical study of isolated patent ductus arteriosus (동맥관 개존증의 임상적 고찰)

  • 곽영태
    • Journal of Chest Surgery
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    • v.17 no.4
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    • pp.593-606
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    • 1984
  • With the ligation of patent ductus arteriosus by Gross in 1938, surgeons first entered the field of congenital heart disease. Interruption of a ductus is one of the most satisfactory and curative operations in the field of surgery for congenital heart disease. 27 cases of isolated patent ductus arteriosus were operated from Jan. 1978 to July 1984 at the Department of Thoracic & Cardiovascular Surgery in Kyung-Hee University Hospital. Retrospective clinical analysis of these patients were: 1. Sex ratio, female: male, was 2:1. 2. Mean age at operation was 9.85\ulcorner.58 years. The youngest patient was a 23 month-old girl and the oldest one was a 24 year-old male. 3. More than half of the patients had less than 50 percentile of growth retardation. 4. Chief complaints of the patients were frequent URI [52%], dyspnea on exertion [33%], generalized weakness [22%], palpitation [7%], but 7 patients [26%] had no subjective symptoms. 5. Continuous machinery murmur could be heard at the 2nd or 3rd intercostal space on the left sternal border in 22 patients [81%]. The other S patients made systolic murmur with accentuation of the second heart sound and those were associated with pulmonary hypertension. 6. Radiologic findings of Chest P-A were cardiac enlargement in 15 patients [55%], enlargement of pulmonary conus and/or increasing density of pulmonary vascularity in 20 patients [74%]. 7. Electrocardiographic findings of the patients were within normal limit in 13 patients [48%], LVH in 4 patients [15%], biventricular hypertrophy in 3 patients [11%]. 8; echocardiogram was obtained from 11 patients. Ductus was directly visualized in 7 patients. Left atrial enlargement is the secondary change of left to right shunt, 10 patients had LA/Ao ratio more than 1.2. 9. Cardiac catheterization performed in 25 patients. The mean value of the results were:SO2[PA-RV]= 14.72\ulcorner6.01%, Qp/Qs=2.22\ulcorner.80, peak systolic pulmonary arterial pressure=48.28\ulcorner1.60 mmHg. 10. 26 patients were operated through the left posterolateral thoracotomy: closure of ductus by double ligation in 14 cases, triple ligation in 5 cases, and division with suture in 8 cases. One patient suffer from aneurysmal rupture of main pulmonary artery, endocarditis, hemopericardium was treated with cardiopulmonary bypass via median sternotomy and closure of ductus through the ruptured main pulmonary artery. 11.There was no death associated with the operation, but 3 cases were experienced with intraoperative rupture around the ductus resulting in massive bleeding. The other complications were transient hoarseness in one patient, atelectasis in left lower lobe in 3 patients, and postoperative systemic hypertension in 4 patients with unknown etiology. 12. Pulse pressure was reduced, 11.47+5.92 mmHg, postoperatively, as compare to preoperative status. 13. Intraoperative wedge lung biopsy from lingular segment for the evaluation of the pulmonary vascular disease was taken in S patients with severe pulmonary hypertension. The result was Heath-Edward grade I in one case, grade II in two cases, and grade III in two cases.

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Geochemistry and Isotope Studies of the Shinchon $CO_2$ -rich Waters in the Gyeongsang Province (경상지역 신촌 탄산약수의 지화학적 및 동위원소 특성)

  • 김건영;고용권;배대석;김천수;박맹언
    • Economic and Environmental Geology
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    • v.34 no.1
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    • pp.71-88
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    • 2001
  • The Geochemica] and isotope studies on the $CO_2$-rich water from the Shinchon area were carried out. The Shinchon $CO_2$-rich water belongs to Ca(Na)-$HCO_3$ type showing very high $P_{CO_{2}}$ ( $10^{-0.35}$ ~ $10^{0.29}$ atm) and TDS (835-3,144 mg/L). The results of geochemical and isotope analysis indicate that $CO_2$ gas is originated from the deep seated source such as mantle or magmatic gases. The $CO_2$-rich water was evolved by interaction with deep-seated granite and major water-rock interaction was dissolution of p]agioclase resulting high Na content of $CO_2$-rich water. Precipitation and dissolution of secondary calcite might be accompanied with the dissolution of plagioclase maintaining Na/Ca ratio. High contents of K and $SO_4$ indicate that the geochemical characteristics of $CO_2$-rich water were partially affected by interaction with upper sedimentary rock during uprising to surface. N03 and tritium contents suggest that the $CO_2$-rich water was mixed with low $CO_2$ groundwater at some locations. The oxygen-hydrogen isotopes show that all water samples were derived from meteoric waters and the $CO_2$-rich water was isotopically re-equilibrated with lighter $CO_2$ gas. Although some carbon isotope data show isotopically heavy values, carbon isotope data indicate that the $CO_2$ gas was possib]y derived by deep source.

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Preliminary Research to Support Air Quality Management Policies for Basic Local Governments in Gyeonggi-do (경기도 기초지자체 대기환경 관리정책 지원을 위한 선행 연구)

  • Chanil Jeon;Jingoo Kang;Minyoung Oh;Jaehyeong Choi;Jonghyun Shin;Chanwon Hwang
    • Journal of Environmental Health Sciences
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    • v.49 no.5
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    • pp.275-288
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    • 2023
  • Background: When basic local governments want to improve their air quality management policies, they need fundamental evidence, such as the effectiveness of current policies or scenario results. Objectives: The purpose of this study is to lay the groundwork for a process to calculate air pollutant reduction from basic local government air quality policies and provide numerical estimates of PM2.5 concentrations following improved policies. Methods: We calculated the amount of air pollutant reduction that can be expected in the research region based on the Gyeonggi-do Air Environment Management Implementation Plan issued in 2021 and guidelines from the Korean Ministry of Environment. The PM2.5 concentration variations were numerically simulated using the CMAQ (photochemical air quality model). Results: The research regions selected were Suwon, Ansan, Yongin, Pyeongtaek, and Hwaseong in consideration of population, air pollutant emissions, and geographical requirements. The expected reduction ratios in 2024 compared to 2018 are CO (3.0%), NOx (7.9%), VOCs (0.7%), SOx (0.1%), PM10 (2.4%), PM2.5 (6.1%), NH3 (0.05%). The reduced PM2.5 concentration ratio was highest in July and lowest in April. The expected concentration reduction of yearly mean PM2.5 in the research region is 0.12 ㎍/m3 (0.6%). Conclusions: Gyeonggi-do is now able to quickly provide air pollutant emission reduction calculations by respective policy scenario and PM2.5 simulation results, including for secondary aerosol particles. In order to provide more generalized results to basic local governments, it is necessary to conduct additional research by expanding the analysis tools and periods.

Adalimumab Treatment in Pediatric-Onset Crohn's Disease Patients after Infliximab Failure: A Single Center Study

  • Song, Won Jae;Kang, Ben;Choi, So Yoon;Choe, Yon Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.19 no.2
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    • pp.116-122
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    • 2016
  • Purpose: We aimed to investigate the efficacy and safety of adalimumab in pediatric-onset Crohn's disease patients who had failed treatment with infliximab. Methods: In this retrospective study, patients included were those who had been diagnosed with Crohn's disease before 18 years old, and had received treatment with adalimumab after infliximab failure. The efficacy of adalimumab treatment was investigated at 1 month and 1 year, and adverse events that had occurred during treatment with adalimumab were explored. Results: Ten patients were included in this study. The median duration from diagnosis to adalimumab treatment was 5.5 years (range: 2.4-7.9 years). At 1 month after adalimumab initiation, 80% (8/10) of patients showed clinical response, and 40% (4/10) achieved clinical remission. At 1 year, 71% (5/7) of patients showed clinical response, and 43% (3/7) were under clinical remission. Among the total included patients, 5 patients (50%) showed clinical response at 1 year. Primary non-response to adalimumab was observed in 2 patients (20%), and secondary failure to adalimumab was observed in 3 patients (30%) during 1 year treatment with adalimumab. No serious adverse event had occurred during adalimumab treatment. Conclusion: Adalimumab was effective for 1 year without serious adverse events in half of pediatric-onset Crohn's disease patients who had failed treatment with infliximab.

A Study on the Reliability Assessment of Sasang Constitution Questionnaire Developed by KIOM for Japanese (일본인 대상자를 통해 살펴본 KIOM 체질 설문지의 신뢰도 평가)

  • Yoo, Jong-Hyang;Jang, Eun-Su;Kim, Yun-Yung;Park, Ki-Hyun;Lee, Si-Woo
    • Journal of Sasang Constitutional Medicine
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    • v.24 no.2
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    • pp.8-18
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    • 2012
  • 1. Objectives : This study aimed to assessing the reliability of questionnaire for Japanese as one of method to diagnose Sasang Constitution and evaluating the possibility of applying domestic questionnaire to foreign site. 2. Methods : A cross-sectional survey approved by IRB (Independent Review Board) at Tohoku University was performed for 119 participants with informed consent at a particular city in Japan using self-reported questionnaires developed by KIOM (Korea Institute of Oriental Medicine). Among the entire samples, 112 were retested. The test-retest reliability was assessed by Kappa for normal variables and internal consistency was evaluated by Cronbach's alpha. 3. Results : Four of 77 questions are impossible to calculate consistency owing to unsymmetric matrix between primary reply and secondary one. Seventeen of them (22%) showed 0.4 or below in Kappa, 56 were ranged from 0.4 to 0.8 and no question marked 0.8 or over. Internal consistency was possibly checked for several questions about character, digestion, sweat, excrement, urine, cold-heat pattern. Cronbach's alpha for questions except urine and cold-heat pattern was over 0.6 4. Conclusions : On the basis of Kappa value by two self reported questionnaire, 72.7% of questions showed 0.4 or over so that reliability were highly secured. And other questions except for urine and heat-cold pattern marked 0.6 or over in order that internal consistency was also successfully maintained. Accordingly, when subsequently applying KIOM questionnaire to foreign site, domestic questionnaire should be properly adjusted in social and cultural background, lifestyle, etc.

Secondary Mineral Formation and Expansion Mechanisms Involved in Concrete Pavement Deterioration (콘크리트 포장 도로의 성능저하에 관련된 이차광물형성과 팽창메카니즘)

  • ;Rober D. Cody
    • The Journal of Engineering Geology
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    • v.12 no.1
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    • pp.95-109
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    • 2002
  • A significant question is what role does newly-formed expansive mineral growth play in the premature deterioration of concrete. These minerals formed in cement paste as a result of chemical reactions involving cement paste and coarse/fine aggregate. Petrographic observations and SEM/EDAX analysis were conducted in order to determine chemical and mineralogical changes in the aggregate and cement paste of samples taken from lowa concrete highways that showed premature deterioration. Formation and expansive mechanisms involved in deterioration were Investigated. Brucite, Mg(OH)$_2$, is potentially expansive mineral that farms in cement paste of concretes containing reactive dolomite aggregate as a result of partial dedolomitization of the aggregate. No cracking was observed to be spatially associated with brucite, but most brucite was microscopic in size and widely disseminated in the cement paste of less durable concretes. Expansion stresses associated with its growth at innumerable microlocations may be retrieved by cracking at weaker locations in the concrete. Ettringite, 3CaO.Al$_2$O$_3$.3CaSO$_4$.32$H_2O$, completely fills many small voids and occurs as rims lining the margin of larger voids. Microscopic ettringite is common disseminated throughout the paste in many samples. Severe cracking of cement paste causing premature deterioration is often closely associated with ettringite locations, and strongly suggests that ettringite contributed to deterioration. Pyrite, FeS2, is commonly present in coarse/fine aggregates, and its oxidation products is observed in many concrete samples. Pyrite oxidation provides sulfate ions for ettringite formation.

Analysis of survey on Secondary Mathematics Teachers' Attitudes toward Teaching and Learning (증등 수학교사의 교수-학습에 대한 태도 조사 분석 - 부산시 및 경상남도 중등 수학교사를 대상으로 -)

  • 이종연;이상백
    • Journal of Educational Research in Mathematics
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    • v.8 no.1
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    • pp.11-29
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    • 1998
  • The purpose of this thesis was to improve the plans and methods of teaching and learning activities and contribute to developing teachers` quality and reeducating them by investigating teachers' attitudes toward teaching and learning have a significant effect on the students' attitudes toward mathematics and the students' ability development at mathematics. The inventory was composed of 56 items : three main areas and eight sub-areas. Added seven background factors were sex, by whom was established (is it a public or nongovernmental \ulcorner), teaching career, age, what kind of school (is it general or vacational high school or middle school\ulcorner), region, college. For this analysis of materials used SAS program. And analysis of variance was applied on the seven background factors. All subjects in this study were 341 secondary school mathematics teachers in pusan city and Kyungsangnam-do were surveyed by the questionnaire of Likert type to which the respondents' seven background elements were added. Main results this study were as follows : 1. The overall attitude of the measured secondary school mathematics teachers tends to be positive but a little indifferent. Also attitude toward the students was a little more positive than the other attitudes. 2. There were significant differences (1%) among the sub-level areas except three of them. (r = 0.17~0.60) 3. There were significant differences (5%) by the result of Multiple comparison test among the schools in learning and teaching. So the teachers working at middle schools and general high schools were more positive than those working at vocational high schools. 4. The result of comparison among region was that teachers working in towns and cities were more positive than those working in the country. But there was no significant difference between the teachers working in large cities and those working in other region. 5. There was no significant difference in the overall attitudes toward teaching and learnig among the sex, by whom was established(is it public or nongovernmental\ulcorner), teaching career, age, college. The study left much deficiency to be desired and has to be followed by a continuing study to make it better. For the following study, it is necessary to examine the validity and reliability of the measuring tools more thoroughly and investigate the attitudes with sufficient samples all over the country.

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Sources Apportionment Estimation of Ambient PM2.5 and Identification of Combustion Sources by Using Concentration Ratios of PAHs (대기 중 PM2.5의 오염기여도 추정 및 PAHs 농도비를 이용한 연소 오염원 확인)

  • Kim, Do-Kyun;Lee, Tae-Jung;Kim, Seong-Cheon;Kim, Dong-Sool
    • Journal of Korean Society for Atmospheric Environment
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    • v.28 no.5
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    • pp.538-555
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    • 2012
  • The purpose of this study was to understand $PM_{2.5}$ chemical characteristics on the Suwon/Yongin area and further to quantitatively estimate $PM_{2.5}$ source contributions. The $PM_{2.5}$ sampling was carried out by a high-volume air sampler at the Kyung Hee University-Global Campus from November, 2010 to October, 2011. The 40 chemical species were then analyzed by using ICP-AES(Ag, Ba, Cr, Cu, Fe, Mn, Ni, Pb, Si, Ti, V and Zn), IC ($Na^+$, $K^+$, $NH_4{^+}$, $Mg^{2+}$, $Ca^{2+}$, $NO_3{^-}$, ${SO_4}^{2-}$ and $Cl^-$), DRI/OGC (OC1, OC2, OC3, OC4, OP, EC1, EC2 and EC3) and GC-FID (acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, benzo[a]anthracene, benzo[b]fluoranthene, benzo[a] pyrene, indeno[1,2,3-cd] pyrene, benzo[g,h,i]perylene and dibenzo[a,h,]anthracene). When applying PMF model after performing proper data treatment, a total of 10 sources was identified and their contributions were quantitatively estimated. The average contribution to $PM_{2.5}$ emitted from each source was determined as follows; 26.3% from secondary aerosol source, 15.5% from soil and road dust emission, 15.3% from vehicle emission, 15.3% from illegal biomass burning, 12.2% from incineration, 7.2% from oil combustion source, 4.9% from industrial related source, and finally 3.2% from coal combustion source. In this study we used the ratios of PAHs concentration as markers to double check whether the sources were reasonably classified or not. Finally we provided basic information on the major $PM_{2.5}$ sources in order to improve the air quality in the study area.

Kinetics and Mechanism of the Oxidation of Alcohols by C9H7NHCrO3Cl (C9H7NHCrO3Cl에 의한 알코올류의 산화반응에서 속도론과 메카니즘)

  • Park, Young-Cho;Kim, Young-Sik;Kim, Soo-Jong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.8
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    • pp.378-384
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    • 2018
  • $C_9H_7NHCrO_3Cl$ was synthesized by reacting $C_9H_7NH$ with chromium (VI) trioxide. The structure of the product was characterized by FT-IR (Fourier transform infrared) spectroscopy and elemental analysis. The oxidation of benzyl alcohol by $C_9H_7NHCrO_3Cl$ in various solvents showed that the reactivity increased with increasing dielectric constant(${\varepsilon}$) in the following order: DMF (N,N'-dimethylformamide) > acetone > chloroform > cyclohexane. The oxidation of alcohols was examined by $C_9H_7NHCrO_3Cl$ in DMF. As a result, $C_9H_7NHCrO_3Cl$ was found to be an efficient oxidizing agent that converts benzyl alcohol, allyl alcohol, primary alcohols, and secondary alcohols to the corresponding aldehydes or ketones (75%-95%). The selective oxidation of alcohols was also examined by $C_9H_7NHCrO_3Cl$ in DMF. $C_9H_7NHCrO_3Cl$ was the selective oxidizing agent of benzyl, allyl and primary alcohol in the presence of secondary ones. In the presence of DMF with an acidic catalyst, such as $H_2SO_4$, $C_9H_7NHCrO_3Cl$ oxidized benzyl alcohol (H) and its derivatives ($p-OCH_3$, $m-CH_3$, $m-OCH_3$, m-Cl, and $m-NO_2$). Electron donating substituents accelerated the reaction rate, whereas electron acceptor groups retarded the reaction rate. The Hammett reaction constant (${\rho}$) was -0.69 (308K). The observed experimental data were used to rationalize hydride ion transfer in the rate-determining step.

A Comparison of Shared Governance and Nursing Unit Culture in Three Hospitals (공유관리와 간호단위문화에 대한 조사;세개 종합병원 대상)

  • Kang, Sun-Joo
    • Journal of Korean Academy of Nursing Administration
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    • v.2 no.1
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    • pp.17-33
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    • 1996
  • The primary purpose this descriptive study was to identify, describe, and compare the patterns of shared governance and nursing unit culture in the hospital settings. The secondary purpose of the research was to identify, describe whether the participation style or responsibility style of nursing management activities shared through nurses in a consistent way. Methodology included survey and in-depth interviews with a total 145 members of 15 nursing units in 3 hospitals. One was a national hospital, another was a corporation hospital and the other was a teaching hospitals. Conclusions from this research included the following: 1. The degree of shared governance in nursing management activities was the highest in the corporation hospital. 2. In the participation style of nursing management activities, 'all participation' was the highest in the corporation hospital. 'Nursing administration only' was the highest in the national hospital. 3. Distribution of responsibility style differed from that of participation style. Three hospitals showed high in nursing management activities such as 'nursing administration only' and 'head nurse only' style. 4. Five experts surveyed showed that the ideal level of nurses' participation in nursing management activities was a traditional nursing governance pattern. 5. There was a distinct difference in the nursing unit culture throughout the institutions in the professional growth. 6. There was no significant difference in the same nursing units of three hospitals in nursing unit culture. According to these results, the following implications can be made; 1. In nursing administration, there should be an emphasis on preparing staff nurses' potential decision-making ability through continuing education so that staff nurses' autonomy and responsibility will be developed and increased. 2. It is necessary to develop a strategic nursing unit for improving nursing quality in hospital setting. 3. The relationship of shared governance, nursing unit culture and nursing outcome should be researched further.

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