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An Analysis of Clinical Research Trends on Interventions of Korean Medicine for Ovarian Cysts (난소 낭종의 한의학적 치료에 대한 국내 임상연구 동향 분석)

  • Jeoung-Yoon Choi;Jin-Moo Lee;Chang-Hoon Lee;Jun-Bock Jang;Deok-Sang Hwang
    • The Journal of Korean Obstetrics and Gynecology
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    • v.36 no.3
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    • pp.25-45
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    • 2023
  • Objectives: The purpose of this study is to review the clinical research trends of ovarian cysts and to recognize the efficacy of Korean medicine intervention. Methods: Based on four domestic databases, including Korean studies Information Service System (KISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Medical Database (KMbase) and Research Information Sharing Service (RISS), we analyzed the case reports using Korean medicine intervention, which include acupuncture, moxibustion and herbal medicine. Data retrieval was carried out from May 12th, to 18th, 2022, and a total of 9 papers were included. Results: All papers were published in Korea and they contain seventeen case reports in total. The most frequently used intervention was herbal medicine, especially Gyejibokryeong-hwan-gami (桂枝茯苓丸加味), Guichulpajing-tang-gagam (歸朮破癥湯加減), Guibiondam-tang-gami (歸脾溫膽湯加味). Most cases reported statistically significant results on using Korean-medicine intervention. Also, there was no serious side effect of Korean medicine. Conclusions: In this study, we investigated the efficacy of Korean medicine intervention as an adjuvant therapy for ovarian cyst patients and research trends on ovarian cysts. Further studies are needed to supplement the safety and the evaluation of Korean medicine. However, the results should be taken cautiously as more clinical studies are needed.

"Where can I buy this?" - Fashion Item Searcher using Instance Segmentation with Mask R-CNN ("이거 어디서 사?" - Mask R-CNN 기반 객체 분할을 활용한 패션 아이템 검색 시스템)

  • Jung, Kyunghee;Choi, Ha nl;Sammy, Y.X.B.;Kim, Hyunsung;Toan, N.D.;Choo, Hyunseung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2022.11a
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    • pp.465-467
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    • 2022
  • Mobile phones have become an essential item nowadays since it provides access to online platform and service fast and easy. Coming to these platforms such as Social Network Service (SNS) for shopping have been a go-to option for many people. However, searching for a specific fashion item in the picture is challenging, where users need to try multiple searches by combining appropriate search keywords. To tackle this problem, we propose a system that could provide immediate access to websites related to fashion items. In the framework, we also propose a deep learning model for an automatic analysis of image contexts using instance segmentation. We use transfer learning by utilizing Deep fashion 2 to maximize our model accuracy. After segmenting all the fashion item objects in the image, the related search information is retrieved when the object is clicked. Furthermore, we successfully deploy our system so that it could be assessable using any web browser. We prove that deep learning could be a promising tool not only for scientific purpose but also applicable to commercial shopping.

Current Trends of Traditional Herbal Medicine Research on Allergic Disease with Dysbiosis (알레르기 질환에서 장내미생물 조절을 통한 한약의 효과 연구동향)

  • Yun-Jung Lee;Min-Hee Kim
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.37 no.1
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    • pp.57-68
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    • 2024
  • Objectives : The purpose of this study is to analyze the current trends of various herbal medicine research on allergic disease with dysbiosis. Methods : Electronic searches were performed using Pubmed, Research Information Sharing Service(RISS), Korean studies Information Service System(KISS), Oriental medicine Advanced Searching Integrated System(OASIS). Results : We analyzed ten studies on the effect of herbal medicine on allergic disease with dysbiosis. Eight studies were animal experimental studies, and two were randomized clinical trial(RCT) study and one-group pretest-posttest research, respectively. Among the studies, three studies were on atopic dermatitis, two on allergic rhinitis, and five on asthma. All different herbal medicines were used in the studies. Changes in gut microbiota composition were observed in nine studies except for 1 RCT study. In eight animal experimental studies, there was significant reduction in allergy-related inflammatory markers. Six studies evaluated the change of metabolites related to gut microbiota and three of them showed significant increase in short-chain fatty acids(SCFA). Conclusion : This study provides current trends of studies on herbal medicine research on allergic disease with dysbiosis. Most research is conducted using animal experiments, and this is a relatively recent trend. These studies offer basic knowledge on the correlation between herbal medicine, gut microbiota, and anti-inflammatory effects in allergic disease.

A Review of Clinical Studies on Acupuncture Application for Abdominal Obesity (복부비만에 활용되는 침치료에 대한 국내외 연구동향)

  • Su-Min Koh;Mi-Yeon Song;Won-Seok Chung;Hyungsuk Kim;Woo-Chul Shin;Seyun Kim;Joonwon Seo;Jae-Heung Cho
    • Journal of Korean Medicine for Obesity Research
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    • v.23 no.2
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    • pp.125-135
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    • 2023
  • Objectives: The purpose of this study was to review current research trends and to provide basic data for the guideline of the acupuncture treatment for abdominal obesity in the clinic. Methods: Publications related to acupuncture treatment for abdominal obesity were retrieved from 9 databases (PubMed, Embase, Scopus, Cochrane Library, Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, Research Information Sharing Service, DataBase Periodical Information Academic, National Discovery for Science Library). Extracted studies were analyzed in terms of publication year, study type, treatment method, acupoint and evaluation method. Results: There were 19 studies about acupuncture treatment applied to abdominal obesity. Electroacupuncture and acupoint catgut embedding therapy was the most frequently studied treatment method. ST25, CV12, SP15, CV6, CV4 was the most frequently used acupoint. Body weight, body mass index, waist circumference and waist-hip ratio was the most frequently used evaluation method. Conclusions: This review identified acupuncture application for abdominal obesity. However, well-designed and conducted clinical trials will be more needed to develop acupuncture treatment for abdominal obesity.

Recent Clinical Research on Acupuncture Therapy for Cluster Headache (군발성 두통에 대한 최근 침치료 연구 동향)

  • Sung-eun Kim;Ae-ri Lee;In Lee
    • The Journal of Internal Korean Medicine
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    • v.44 no.6
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    • pp.1197-1211
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    • 2023
  • Objectives: This study presents evidence by analyzing the research trends in acupuncture treatment for cluster headache in the last 10 years. Methods: Randomized controlled trials (RCTs) about acupuncture for cluster headache were searched from the China National Knowledge Infrastructure, PubMed, Cochrane Library, Oriental Medicine Advanced Searching Integrated System, ScienceON, Korean Studies Information Service System, and Research Information Sharing Service. The search terms were the combinations of "cluster headache", "acupuncture", and "needle therapy", and the articles were restricted to those published between 2013 and 2023. Only RCTs were selected. The risk of bias (RoB) was assessed according to the revised Cochrane RoB2 criteria. Results: Six RCTs were selected and analyzed in this review. All selected studies were conducted in China. All RCTs comprised 628 participants. Manual acupuncture was used in all studies. Acupuncture targeting the sphenopalatine ganglion was performed in two papers published after 2020. ST8, Ex-HIN3, and GB14 were the most frequently used acupoints in acupuncture treatment. The most commonly used indicators for evaluation were headache attack frequency, clinical efficacy, and the visual analog scale. In each study, adding acupuncture treatment to conventional therapy had significant effects in relieving the symptoms of cluster headaches. Conclusion: The results suggest that acupuncture is an effective treatment for cluster headache. To ensure objective evidence for the effectiveness of acupuncture treatment in cluster headache, it is important to continue large-scale case reports and RCTs.

Recent Domestic and International Clinical Research Trends in Gua Sha Therapy: A Scoping Review (괄사요법의 국내외 최신 임상 연구 동향: 주제범위 문헌고찰)

  • Seungwon Jung;Seungkwan Choi;Jungho Jo;Yunhee Han;Hyeonjun Woo;Byeonghyeon Jeon;Wonbae Ha;Junghan Lee
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.1
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    • pp.23-38
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    • 2024
  • Objectives This study examined recent domestic and international clinical research trends in Gua sha therapy to suggest future direction for research. Methods We used six domestic and international databases (Research Information Sharing Service, Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, PubMed, Embase, Cochrane Library) to select clinical studies with an original text in English or Korean published after 2018. Results Finally, 55 studies were selected. Randomized controlled trials accounted for the largest amount with 42 studies. Instrument assisted soft tissue mobilization was the most frequent term referring to Gua sha. Muscle shortening, limited range of motion, and plantar fasciitis were the most common symptoms, with six cases each. Additionally, there were two studies targeting symptoms other than the musculoskeletal system. Conclusions Additional research is needed on the effects of Gua sha therapy on the back of the lower extremities and hip joints, and research is needed on the possibility of their clinical use for diseases or symptoms other than those of the musculoskeletal system. And standards for the terminology of Gua sha and the types and methods of applied interventions are needed.

Therapeutic Effects of Acupuncture for Shoulder Impingement Syndrome: A Systematic Review and Meta-Analysis (어깨충돌증후군에 대한 침치료의 효과: 체계적 문헌고찰 및 메타분석)

  • Jeong Hoon Ahn;Gun Hee Bae;Byung-Jun Kim;In-Hwa Park;In Heo;Yun-Yeop Cha
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.1
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    • pp.83-95
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    • 2024
  • Objectives This review was conducted to evaluate the therapeutic effects of manual acupuncture (MA) for shoulder impingement syndrome (SIS). Methods We searched 12 electronic databases (DBpia, Korean studies Information Service System [KISS], Oriental Medicine Advanced Searching Integrated System [OASIS], Research Information Sharing Service [RISS], China National Knowledge Infrastructure [CNKI], CINAHL, Clinical Key, Cochrane Library, Embase, JAMA, PubMed, Web of Science) to find randomized-controlled clinical trials (RCTs) investigating therapeutic effects of MA for treating SIS. Shoulder Pain and Disability Index scores and numeric pain rating scale or visual analogue scale were analyzed as the main evaluation criteria. Results Among 181 studies, 169 were screened and only 12 RCTs were eligible in our review. Finally, 11 RCTs could be statistically analyzed. MA was more effective than sham treatment and physical therapy in terms of reducing pain (p=0.003, p=0.0007 each). Electroacupuncture (EA) showed more significant effect than physical therapy (PT) for improving shoulder pain (p<0.00001) and shoulder functionality (p<0.00001). Conclusions These results suggest that MA and EA could be superior option for treating SIS than sham treatment or PT. However this review has its limitations due to the small sample size and lack of well-designed RCTs that were included in the study. Further well-designed RCTs are necessary to provide high-level evidence.

Electroacupuncture for Rotator Cuff Disorder: A Systematic Review and Meta-Analysis (회전근개 질환의 전침 치료에 대한 체계적 문헌고찰 및 메타분석)

  • Bok-Yeon Na;Sang-Hoon Lee;Chang-Hoon Woo;Young-Jun Kim
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.3
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    • pp.27-41
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    • 2024
  • Objectives This study aims to evaluate the efficacy and safety of electroacupuncture for rotator cuff disorder. Methods We searched nine online databases (PubMed, Embase, Cochrane Library, Chinese Academic Journals, Korean studies Information Service System, Rsearch Information Sharing Service, ScienceON, KMbase, Oriental Medicine Advanced Searching Integrated System) and two related journals up to April 2024 to identify randomized controlled trials that applied electroacupuncture to rotator cuff disorder. Selected studies were analyzed for risk of bias using the Cochrane risk of bias tool, and a meta-analysis was performed with RevMan version 5.4.1. Results Out of 175 studies, eleven randomized controlled trials were selected for final analysis. Most studies showed that electroacupuncture had effect on rotator cuff disorder. In the meta-analysis, electroacupuncture combined with rehabilitation treatment was significantly more effective than rehabilitation treatment alone in improving visual analog scale (p<0.00001). Almost studies did not report any side effects or adverse reactions to electroacupuncture treatment. Conclusions This systematic review suggests that electroacupuncture is an effective treatment for pain management in rotator cuff disorder. However, the lack of adverse effect reporting and a high risk of bias indicate the need for high-quality randomized controlled trials from various countries.

A Review on the Effect of Traditional Medicine Treatments in Korea and China for Recurrent Lumbar Disc Herniation: Systematic Review and Meta-Analysis (재발성 요추간판탈출증의 한의학적 치료에 대한 국내·외 연구 동향 체계적 문헌고찰 및 메타분석)

  • Ah-Ra Koh;Young-Jin Lee;Ji-Eun Choi;So-Jung Kim;Hyun-Woo Kim;Hye-Jeong Jo;Go-Eun Chae
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.3
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    • pp.13-26
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    • 2024
  • Objectives This study aimed to examine the efficacy of Korean traditional medicine treatments for recurrent lumbar disc herniation by analyzing randomized controlled trials (RCTs). Methods The following 6 databases were used Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, ScienceON, PubMed, and China National Knowledge Infrastructure. Only RCTs were selected. The risk of bias was assessed by Cochrane's risk of bias tool. Results A total of 10 RCTs were analyzed, which utilized 8 types of interventions, including acupuncture, moxibustion, warm needling, electroacupuncture, herbal medicine, cupping, and chuna manual therapy. Acupuncture and moxibustion were the most frequently used treatments. There were 7 outcome measures, including the effective rate, visual analog scale, Japanese Orthopedic Association. The effective rate was assessed in all studies. Meta-analysis results indicated that warm needling therapy and traditional Chinese medicine interventions were more effective compared with the control. Conclusions In this study, warm needling therapy and herbal medicine interventions demonstrated beneficial effects. As the meta-analysis was conducted with only a subset of RCT studies, further large-scale, systematic RCT studies are needed.

A Literature Review of Domestic Clinical Studies on Chungsangboha-tang (Qingshangbuxia-tang) (청상보하탕에 대한 국내 임상연구 동향 분석)

  • Ji won Park
    • Herbal Formula Science
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    • v.32 no.3
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    • pp.325-343
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    • 2024
  • Objective : To understand how Chungsangboha-tang (CSBHT) is being utilized in clinical practice and research in Korea, clinical studies related to CSBHT published in domestic academic journals were analyzed. Methods : The search was conducted using the following six databases: Korean Traditional Knowledge Portal, Oriental Medicine Advanced Searching Integrated System, ScienceON, Research Information Sharing Service, Koreanstudies Information Service System, and The Journal of Internal Korean Medicine. After selecting relevant literature published before June 24, 2024, the studies were classified and analyzed according to their research design. Results : The final selection comprised 20 studies categorized as follows: 1 non-randomized controlled trial and 10 before-and-after studies in prospective clinical research, along with 7 case reports and 2 retrospective chart reviews in retrospective clinical studies. Among the 233 participants included in these studies, 169 had asthma, 53 had chronic cough, and 5 had chronic obstructive pulmonary disease. Additionally, other conditions reported included Churg-Strauss syndrome, pulmonary Langerhans cell histiocytosis, non-tuberculous mycobacterial pulmonary disease, bronchiectasis, and pulmonary hypertension. CSBHT was administered as a decoction in 13 studies, as granules in 6 studies, and both in one study. The most frequently used assessment tools were pulmonary function tests and quality of life evaluations. For safety assessment, liver function test results and adverse events were reported. Conclusion : To enhance the utilization of CSBHT in Korean medicine clinical practice, continuous accumulation of domestic clinical research is essential. Moreover, meticulously designed randomized controlled trials are necessary to elevate the level of evidence.