• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.545-547
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• 2003

A tyrosinase inhibitor, Lonjapoin, was isolated from the ethanolic extracts of Flos Lonicera by activity-guided fractionation. Lonjapoin ($IC_{50}$/; 2.07 $\mu\textrm{g}$/mL) was found to be potentially as effective inhibitor of production of melamin. Flos Lonicera (Jinyinhua) is the dry flower buds of Lonicera japonica. Thunb. It is used as an antibacterial and antiphlogistic agent in the treatment of abscess, laryngeal catarrh, erysipelas, dysentery, cold and fever. In our continuing search for natural source as cosmetic ingredients from Chinese medicinal herbs and found the extracts of Flos Lonicera showed the significant tyrosinase inhibition activity. In this study the active constituent of Lonicera japonica. obtained with the process of tyrosinase activity assay and column chromatography.

• Archives of Pharmacal Research
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• v.21 no.1
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• pp.24-29
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• 1998

To search for the anti-diabetic principle from the stem bark of Kalopanax pictus, seven kinds of chemical constituents including hederagenin glycosides and phenolic glycosides wre isolated. The anti-diabetic evaluation of these isoltes in the streptozotocin-induced diabetic rats exhibited that kalopanaxsaponin A has a potent anti-diabetic activity in contrast to a mild activity of hederagenin. In addition, significant hypocholesterolemic and hypolipidemic activities of kalopanaxsaponin A and hederagenin were observed. The structure-activity relationship of kalopanaxsaponin A was also investigated in the present work.

• YAKHAK HOEJI
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• v.43 no.6
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• pp.771-775
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• 1999

The antimutagenic activities of the total extract and several fractions of starfish, Asterina pectinifera (Asteriidae), were investigated in vitro by SOS chromotest with Escherichia coli PQ37 and Ames test with Salmonella typhimurium TA100. When various fractions was tested, the chloroform and butanol fractions showed low induction factors, which means both fractions increased antigenotoxicity against the base substitution mutagen MNNG. Even though higher antigenotoxic effect of the chloroform fraction, no effective result of Ames test was found in revertant formation of S. typhimurium TA100. The most effective antigenotoxic and antimutagenic fraction was a butanol one: i.e., When 0.5 mg/tube of butanol fraction was applied, the induction factor was 0.68. As the concentration of the fraction was increased the formation of revertants of S. typhimurium TA100 by about 81%. There was no cytotoxic effect of butanol fraction against S.typhimurium TA100. This result might be useful for further study to search a possible anticancer agent from the starfish, Asterina pectinifera.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.52 no.5
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• pp.295-304
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• 2003

In this paper, we proposed a hardware-oriented Genetic Algorithm Processor(GAP) based on subpopulation architecture for high-performance convergence and reducing computation time. The proposed architecture was applied to enhancing population diversity for correspondence to premature convergence. In addition, the crossover operator selection and linear ranking subpop selection were newly employed for efficient exploration. As stochastic search space selection through linear ranking and suitable genetic operator selection with respect to the convergence state of each subpopulation was used, the elapsed time of searching optimal solution was shortened. In the experiments, the computation speed was increased by over $10\%$ compared to survival-based GA and Modified-tournament GA. Especially, increased by over $20\%$ in the multi-modal function. The proposed Subpop GA processor was implemented on FPGA device APEX EP20K600EBC652-3 of AGENT 2000 design kit.

• Proceedings of the KAIS Fall Conference
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• 2010.05a
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• pp.487-490
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• 2010

비디오 데이터를 효율적으로 처리하기 위해서는 비디오 데이터가 가지고 있는 내용에 대한 정보를 데이터베이스에 저장하고 사용자들의 다양한 질의를 처리할 수 있는 의미기반 검색 기법이 요구된다. 기존의 내용기반 비디오 검색 시스템들은 주석기반 검색 또는 특징기반 검색과 같은 단일 방식으로만 검색을 하므로 검색 효율이 낮을 뿐 아니라 완전한 자동 처리가 되지 않아 시스템 관리자나 주석자의 많은 노력을 요구한다. 본 논문에서는 주석기반 검색과 특징기반 검색을 이용하여 대용량의 비디오 데이터에 대한 사용자의 다양한 의미검색을 지원하는 에이전트 기반에서의 자동화되고 통합된 비디오 의미기반 검색 시스템을 제안한다. 사용자의 기본적인 질의와 질의에 의해 추출된 키 프레임의 이미지를 선택함으로써 에이전트는 추출된 키 프레임의 주석에 대한 의미를 더욱 구체화시킨다. 또한, 사용자에 의해 선택된 키 프레임은 질의 이미지가 되어 제안하는 특징기반 검색기법을 통해 가장 유사한 키 프레임을 검색한다. 따라서 의미기반 검색을 통해 비디오 데이터의 검색의 효율을 높일 수 있도록 시스템을 설계한다.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.949-951
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• 2003

To improve the reusability and interoperability of GIS components, we propose the registration/retrieval agents, which can search the locating of users' frequently used components in not only the GIS domain but also other spatial information technologies such as GPS, ITS, RS and FM. The registration/retrieval agents increase the reusability through the GIS component based development under distributed GIS components environment and enables the rapid setting of application on the web. Moreover, users can understand easily the information of GIS component and have the effective investment, timeliness and reliability while they have less maintenance effort by agent. In order to design and implement this system on web, HTML and ASP (Active Serve Page), and JAVA were used. In addition, the performance of this system was verified through comparing others, which are similar to.

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.394-400
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• 2000

Tumor cell interaction with the extracellular matrix (ECM) is defined as the critical event of tumor invasion that signals the initiation of a metastatic cascade. To search for anti-metastatic agent from plants, several plant extracts were screened by cell- ECM anti-adhesion test. As result, Boehmeria pannosa, Dryopteris crassirhizoma, Scilla scilloides, and Agrimonia pilosa were shown a significant anti-adhesion activity.

• Journal of Intelligence and Information Systems
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• v.10 no.2
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• pp.147-163
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• 2004

For the purchase of a cheaper product on the Internet, many customers have been trying to search online shopping mall sites and visit comparison-pricing shops that compare prices and other criteria of the product. Others have been participating into online auction markets or group-buying markets. However, a lot of online shopping malls, auction markets, and group-buying markets provide the same product with different prices. Since these marketplaces have different price settlement mechanism, it is very difficult for the customers to determine marketplace to purchase, considering different kinds of marketplaces at the same time. To overcome such limitations, decision rules and solution procedures for purchase decision making are necessary, which can cover multiple marketplaces simultaneously. For this purpose, purchase decision making in each market must be conducted to maximize customer's utility, and conflicts with other marketplaces must be resolved. Therefore, we have developed the rules and methods that can negotiate cooperatively the purchase decision making in several marketplaces, and designed an architecture of Intelligent Buyer Agent and a message structure to support the idea.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7567-7573
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• 2015

Background: Catastrophic effects of mustard gas as a chemical warfare agent have always been a major problem for those exposed to this agent. In this meta-analysis it was tried to evaluate carcinogenesis, ocular, cutaneous and respiratory complications of mustard gas exposure among Iranians who had been exposed to this agent during the Iran-Iraq war. Materials and Methods: In this meta-analysis, the required data were collected using keywords "mustard gas", "sulfur mustard", "cancer", "neoplasm", "respiratory complications", "ocular complications", "lung disease", "chronic complication", "eye", "skin", "cutaneous complication", "carcinogenesis" and their combination with keywords "Iran", "Iranian", "prevalence", "mortality" and their Farsi equivalent terms from the databases of SID, Iranmedex, Magiran, Pubmed, Science Direct, Google Search engine, Gray Literature and Reference of References. To determine the prevalence of each complication and perform meta-analysis, CMA: 2 (Comprehensive Meta-Analysis) software with a randomized model was used. Results: Of the 542 articles found, 7 national articles, consistent with the aims of this study were selected. Meta-analysis of seven papers revealed that cancer risk, especially cancer of the respiratory system was elevated, so that the relative risk (RR) of cancer role of mustard gas was inconsistent from 2/1 to 4 in this survey. Also prevalence of delayed skin disorders due to sulfur mustard was 94.6%, pulmonary complications 94.5% and ocular complications 89.9%. The incidence of various cancers in victims exposed to mustard gas was 1.7% worldwide where the rate was 2.2% in Iranian victims of the Iraq-Iran war. Conclusions: Based on present study the prevalence of delayed mustard gas related cutaneous, pulmonary and ocular complications is above 90% and risk of carcinogenesis is higher in comparison to worldwide statistics. This may suggest need for long-term and persistent follow-up and rehabilitation procedures for populations exposed to this agent.

• Journal of KIISE:Information Networking
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• v.35 no.5
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• pp.367-373
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• 2008

Recently, the NAT middlebox widely deployed in the home network environment prohibits DM operations from reaching user devices behind NAT. In this article, we focus on NAT issues to manage home network devices. Particularly, we discuss standardization efforts, and present our proposal to deploy DM services for VoIP and IPTV devices under NAT. By slightly changing behaviors of Simple Network Management Protocol (SNMP) Manager and Agent, and defining additional Management Objects (MOs) to gather NAT binding information, we could solve the NAT traversal problem under symmetric NAT. Moreover, we propose an enhanced method to search the UDP hole binding time of the NAT box. We applied our method to randomly selected 22 VoIP devices out of 194 NATed hosts in the real broadband network and have achieved 99% of the success ratio for exchanging SNMP request messages and 26% of enhancement for searching the UDP hole binding time.