Korean Journal of Pharmacognosy (생약학회지)
- Volume 31 Issue 4
- /
- Pages.394-400
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- 2000
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- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Inhibitory activity of plant extracts on Cell-ECM adhesion
암세포에 대한 식물 추출물의 세포외 기질 접착저해 활성
- Lee, Sang-Myung (Korea Research Institute of Bioscience and Biotechnology) ;
- Lee, Ho-Jae (Korea Research Institute of Bioscience and Biotechnology) ;
-
Lee, Choong-Hwan
(Korea Research Institute of Bioscience and Biotechnology)
;
- An, Ren Bo (College of Pharmacy, Chungnam National University) ;
- Na, Min-Kyun (College of Pharmacy, Chungnam National University) ;
- Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
- Kho, Yung-Hee (Korea Research Institute of Bioscience and Biotechnology)
- 이상명 (한국생명공학연구원) ;
- 이호재 (한국생명공학연구원) ;
-
이충환
(한국생명공학연구원)
;
- 안인파 (충남대학교 약학대학) ;
- 나민균 (충남대학교 약학대학) ;
- 배기환 (충남대학교 약학대학) ;
- 고영희 (한국생명공학연구원)
- Published : 2000.12.30
Abstract
Tumor cell interaction with the extracellular matrix (ECM) is defined as the critical event of tumor invasion that signals the initiation of a metastatic cascade. To search for anti-metastatic agent from plants, several plant extracts were screened by cell- ECM anti-adhesion test. As result, Boehmeria pannosa, Dryopteris crassirhizoma, Scilla scilloides, and Agrimonia pilosa were shown a significant anti-adhesion activity.