• BMB Reports
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• v.41 no.5
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• pp.345-352
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• 2008

The cerebral microvessels possess barrier characteristics which are tightly sealed excluding many toxic substances and protecting neural tissues. The specialized blood-neural barriers as well as the cerebral microvascular barrier are recognized in the retina, inner ear, spinal cord, and cerebrospinal fluid. Microvascular endothelial cells in the brain closely interact with other components such as astrocytes, pericytes, perivascular microglia and neurons to form functional 'neurovascular unit'. Communication between endothelial cells and other surrounding cells enhances the barrier functions, consequently resulting in maintenance and elaboration of proper brain homeostasis. Furthermore, the disruption of the neurovascular unit is closely involved in cerebrovascular disorders. In this review, we focus on the location and function of these various blood-neural barriers, and the importance of the cell-to-cell communication for development and maintenance of the barrier integrity at the neurovascular unit. We also demonstrate the close relation between the alteration of the blood-neural barriers and cerebrovascular disorders.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.956-961
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• 2000

This paper describes the design of a small size Alkali Metal Thermal to Electric Converter (AMTEC) which employs a capillary structure for recirculating sodium working fluid. The cycle is based on the simple and small capillary type ${\beta}"$ -alumina and wick tube element. The proposed cell consists of the 37 conversion elements with capillary tube of $50{\mu}m$ in diameter and the sealed cylindrical vessel of 22mm in outer diameter. Results on the cycle analysis of sodium flow and heat transfer in the cell showed that the expected power output was 4.65W and the conversion efficiency was 19% for the source temperature of 900K.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.50 no.7
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• pp.351-363
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• 2001

This paper presents an experimental investigation on the heat trensfer characteristic of micro pipe (MHP) array with 38 triangular microgrooves. A heat pipe is an effective heat exchanger operating without external power. The heat pipe transfers heat by means of the latent heat of vaporization and two-phase fluid flow driven by the capillary force. The overall size of the MHP array can be put undermeath a microelectonic die and integrated into the electrronic package of a microelectronin device to dissipate the heat from the die. The MHP array is fabricated by micromachining with a silicon wafer and a glass substrate. The MHP was filled with water and sealed. The experimental results show the temperature decrease of 12.1$^{\circ}C$ at the evaporator section for the input power of 5.9 W and the improvement of 28% in the heat transfer rate.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1983.05a
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• pp.20-20
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• 1983

A 40-year-old man was admitted with chief complaints of sudden hearing loss, ear fullness and tinnitus of 12 days duration developed following SCUBA diving. An exploratory tympanotomy was done on 16th day of onset, and a small leakage of clear fluid was found on the anterior portion of the stapediovestibular joint, which was sealed off by small piece of fatty tissue from the ear lobe. Postoperatively, his PTA's was improved from 85㏈ to 15㏈, however high tone was remained unchanged above 4KHz. More exploration of the middle ear will be helpful to find the labyrinthine fistula causing sudden type of hearing loss.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.572-575
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• 2005

A microlens connected to microfluidic channel is fabricated. The microlens is sealed with an elastomeric membrane which deforms by pressure of fluid driven by a syringe pump resulting in the shape change of the microlens. The optical properties of the microlens could be controlled by changing the microlens shape. The microlens system were made of an elastomer, PDMS, using molding from a photoplastic master patterned by UV photolithography. The test results show the optical property of the lens could be made into convex and concave type by applying the fluidic pressure positive and negative.

• Archives of Plastic Surgery
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• v.38 no.1
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• pp.121-126
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• 2011

Purpose: Vaccum-assisted closure (VAC) has rapidly evolved into a widely accepted treatment of contaminated wounds, envenomations, infiltrations, and wound complications. This results in a sealed, moist environment where tissue is given the opportunity to survive as edema is removed and perfusion is increased. Many plastic surgeons now place a VAC device directly over the fasciotomy site at the time of the initial procedure. Large amounts of the fluid are withdrawn, and fasciotomies can be closed primarily sooner. This study was designed to observe the effect of VAC in preventing complications in snake bitten hands. Methods: In our study of three cases of snake bite, three of them underwent the VAC treatment & fasciotomy of the wound in the hand. This cases, the posterior compartment of the hand was bitten for a few days, releasing incisions were made of the posterior hand and 125 mmHg of continuous vacuum was applied to fasciomy incision site and the biting wound. The dressings were changed three times per week. Results: Our study examining the effects of applied vacuum in preventing snake bite wounds showed that the incidence of tissue necrosis and compartment syndrome was significantly lower for vacuum-treated wounds than for conservative wounds. Serum myoglobin, CK-MB, and CPK levels measured after fasciotomy incision were significantly decreased. We obtained satisfactory results from early dorsal fasciotomy, drainage of the edema with the VAC system, and then primary closure. The postoperative course was uneventful. Conclusion: Envenomation is a term implying that sufficient venom has been introduced into the body to cause either local signs at the site of the bite and/or systemic signs. Use of the vacuum-assisted closure device in snake bite can result in a decreased rate of tissue necrosis, lymphatic fluid collection, hemolytic fluid collection, and edema. Early fasciotomy of the dorsal hand and VAC apply is the alternative treatment of the snake bite.

• Tunnel and Underground Space
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• v.32 no.4
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• pp.272-284
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• 2022

This study conducted tunnel blasting to evaluate the blasting effect of a shear thickening fluid-based blasting stemming material and a sealed plug device under development. STF single stemming and STF stemming materials were combined with plugs to a tunnel blasting to which the SAV-Cut method was applied, and the advanced rate and fragmentation of tunnel blasting muck pile were compared when sand stemming was used. Tunnel advanced rate was evaluated using a 3D laser scanner. When the STF stemming material and STF stemming material with the plug were compared to the sand stemming material, it increased by 5.7 and 5.36%, respectively. As a result of evaluation of the fragmentation of tunnel blasting muck pile, it was the best when the STF stemming material was applied, and it decreased by about 61% compared to the case of sand stemming blasting. However, no significant improvement in blasting effect was observed with the application of plug devices.

• Journal of the Korea Institute of Building Construction
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• v.18 no.1
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• pp.25-31
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• 2018

In this study, the Controlled Low Strength Material (CLSM) was investigated to utilize the bottom ash and fly ash generated in the Circulating Fluidized Bed Combustor (CFBC). It was confirmed that the CFBC fly ash (CFBC-F) and CFBC bottom ash (CFBC-B) had an irregular particle shape through SEM measurement. According to the results of the hazard analysis, it was also confirmed that they were environmentally safe. In the case of mixing with CFBC-F, the unit quantity was increased. Regarding the rate of change of length, shrinkage in the range of -0.05~0.50% occurred in the air dry curing condition and expansion in the range of 0.1~0.6% in the sealed curing condition. Compressive strength was increased in the sealed curing condition compared to the air dry curing condition because there was enough moisture for hydration reaction in the long term. Therefore, the results of this study are likely be used as basic research data of mine filler materials.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.16 no.4
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• pp.364-374
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• 2006

Natural ventilation technique could be the substitute for or the complement to the local exhaust ventilation system in the sense of protecting work environment. Moreover, it has many strong points ; almost no mechanical parts, no energy use and no noise. If applied appropriately, it could have the very high ventilation rate and save a lot of energy expense. But, it depends on the outdoor environment, especially temperature and wind speed/direction. Predicting the capacity of natural ventilation is not an easy job because it comes from both buoyancy and wind effect. Another problem is too much flow through the ventilator especially in winter time due to too much difference between indoor and outdoor temperature. Thus some ventilators in industries are sealed by door or plastic sheet, resulting in bad work environment. Various types of dampers are used to control the flow rate through ventilators. The capabilities of flow control by damper has not been estimated. In addition, it was not tested whether the damper could obstruct the flow through ventilator when fully opened. To answer these questions, 4 types of dampers were tested by using computational fluid dynamics. 10 different configurations includes no damper, full open and half open. Flow rates were estimated and airflow fields were analysed to clarify the before-mentioned questions. The dual type damper was the best choice for controling the capability of ventilator. In addition, the upward grill type damper was the best for not obstructing the air flow when fully opened.

• The KSFM Journal of Fluid Machinery
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• v.14 no.3
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• pp.23-27
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• 2011

Due to a roots type medium vacuum pump is operated in condition of $1{\sim}10^{-3}$ torr vacuum, it could be applied for production and process of industrial parts, such as precise processing, vaporization, enrichment, separation, casting, metaling, welding, transportation. Therefore, the demand of this pump is increasing nowadays in our industrial markets of semiconductor, electric, electronic, automobile, material, environmental and transporting industries. However, the pumps are almost imported, because the domestic pumps are inferior in fields of vacuum range as under $10^{-1}$torr, relevant techniques(design, fabrication, casting, test, etc.) to the imported ones. In this study, essential parts of the development pump are designed with using of CFD and 3D decodes, FEM for analysing strength and deformation, generated heat, vibration and noise control, and are casted with using of mechanochemistry techniques for decreasing of weights, increasing of heat resistances and abrasion durability of materials for pump caing and impellers especially. Besides, in order to achieve ultimate vacuum around $10^{-3}$torr, this pump is composed of 6 stages, among which 1st stage is operated separately from remained stages. Additionally, a test rig for prototype pumps(300$m^3/h$ and 2,500$m^3/h$) is designed and procured as to apply for multi-staged rootz type vacuum pump, with modification of the test method recommended by KS B 6314 "Positive-displacement oil-sealed rotary vacuum pumps".