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Increased Wall Enhancement Extent Representing Higher Rupture Risk of Unruptured Intracranial Aneurysms

  • Jiang, Yeqing;Xu, Feng;Huang, Lei;Lu, Gang;Ge, Liang;Wan, Hailin;Geng, Daoying;Zhang, Xiaolong
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.189-197
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    • 2021
  • Objective : This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods : One hundred and eight patients with 127 unruptured aneurysms were prospectively enrolled from Feburary 2016 to October 2017. Aneurysms were divided into high risk (≥10) and intermediate-low risk group (<10) according to the PHASES (Population, Hypertension, Age, Size of aneurysm, Earlier SAH history from another aneurysm, Site of aneurysm) scores. Clinical risk factors, aneurysm morphology, and wall enhancement index (WEI) calculated using 3D MR-VWI were analyzed and compared. Results : In comparison of high-risk and intermediated-low risk groups, univariate analysis showed that neck width (4.5±3.3 mm vs. 3.4±1.7 mm, p=0.002), the presence of wall enhancement (100.0% vs. 62.9%, p<0.001), and WEI (1.6±0.6 vs. 0.8±0.8, p<0.001) were significantly associated with high rupture risk. Multivariate regression analysis revealed that WEI was the most important factor in predicting high rupture risk (odds ratio, 2.6; 95% confidence interval, 1.4-4.9; p=0.002). The receiver operating characteristic (ROC) curve analysis can efficiently differentiate higher risk aneurysms (area under the curve, 0.780; p<0.001) which have a reliable WEI cutoff value (1.04; sensitivity, 0.833; specificity, 0.67) predictive of high rupture risk. Conclusion : Aneurysms with higher rupture risk based on PHASES score demonstrate increased neck width, wall enhancement, and the enhancement intensity. Higher WEI in unruptured aneurysms has a predictive value for increased rupture risk.

An Comparative Analysis of Certification Results for Pre-Certified Office Buildings according to G-SEED Revisions (녹색건축 인증제도 업무용 건축물 개정 전·후 인증결과 비교분석)

  • Yun, Yo-Sun;Chae, Chang-U;Kim, Yu-Jin
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.8
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    • pp.51-58
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    • 2018
  • G-SEED has been introduced with the aim of reducing energy use and resources since 2002, as the system of certificating environmental friendliness of buildings to create comfortable environment. This study analyzed the changes of certification standard of G-SEED since the revision in 2016, comparing certification results of office buildings by grade, category and certification items between G-SEED 2013-2 version and revised version of 2016. Also, this study analyzed the average points and their standard deviation of certification items including both deleted items and newly added items and extracted items needed to be reviewed in the future revision. In the revision, G-SEED has been extended its certification system to involve existing buildings and Innovative Design categories newly introduced with revising the certification items and difficulties. In revised version of G-SEED, the certification grade appeared to change its acquisition ratio decreasing Green2 and increasing Green4, during Green1 and Green3 were similar in proportion. The average scores by categories appeared decrease in Energy and Environmental Pollution category and Materials and Resources category, on the other hand, Maintenance category appeared the highest increase in the average score. Otherwise, Land Use and Transportation, Water Circulation, Ecology, Indoor Environment categories appeared similar average scores both version of G-SEED. In addition, the Innovative Design which was newly introduced category, seems to expect gradual gaining high scores according to technology development in future, although its possession has shown lower scores in revised version.

Survey Research for Evaluation of Real-time Non-face-to-face Medical Education in Clinical Korean Medicine (임상한의학 실시간 비대면교육의 평가를 위한 설문조사 연구)

  • Yang, Seung-Bo
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.984-992
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    • 2020
  • Objectives: This survey research was conducted to evaluate real-time non-face-to-face education in clinical Korean medicine conducted during the COVID-19 outbreak. Methods: This study was conducted with all 3rd and 4th grade students of the Department of Korean Medicine, Gachon University. The Korean Internal Medicine (Pulmonary) lecture course was held from April 1st to July 1st, 2020 for one semester. The lectures were conducted through real-time non-face-to-face education using the Cisco Webex program, and the lectures were mainly conducted by sharing a PowerPoint summarizing textbook. The questionnaire consisted of 3 parts and a total of 18 questions. The survey was conducted anonymously to ensure the confidentiality of all responses. Results: The overall score for real-time non-face-to-face education was 74.69±18.15 points. The efficiency of real-time non-face-to-face education was 2.12±0.78 points, and opinions on the expansion of future use were 2.08±0.91 points and were generally positive. The ratio of non-face-to-face education and face-to-face education in future clinical Korean medicine theory lectures was about 63:27, with a higher proportion of non-face-to-face education. Conclusions: Promoting clinical Korean medicine as a non-face-to-face education has generally been positively evaluated in terms of efficiency and overall, and its use should be expanded in the future. In particular, it will be necessary to use non-face-to-face education in the theory classes of clinical Korean medicine. However, technical problems involving internet, video, equipment, and communication tools will need to be improved in the future.

Effect of eco-friendly restoration on the community characteristics of benthic macroinvertebrates in forested bog (산지습지의 친환경복원이 저서성 대형무척추동물 분포에 미치는 영향)

  • Jung, Yu-Gyeong;Lee, Heon-Ho;Kang, Won-Seok;Park, Ki-Hyung;Kwon, Se-Myung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.24 no.3
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    • pp.33-47
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    • 2021
  • This study was conducted to investigate the influence of eco-friendly restoration in forested bog on the structure of benthic macroinvertebrate community. The benthic macroinvertebrates collected from the surveyed sites were composed of 1,071 individuals, 60 species, 40 families, 13 orders, 6 classes and 5 phyla. At the control and Site 3(small dam), the number of species and individuals were larger than that of other sites, and EPT group ratio was same as well. Considered by index, the dominance index (DI) was found the highest at the biotope area. The diversity index (H') and richness index (RI) were the highest at the control and Site 3. In addition, the ecological score of benthic macroinvertebrate (ESB) showed the highest at site 3, while the lowest at biotope area. The stability and recovery of benthic macrointebrates showed different according to restoration types at forested bog. After restoration project, the benthic macroinvertebrates were observed to get recovery at Site 3, and to have the highest communities stability at control and Site 3. At biotope areas (Site 4, Site 5 and Site 6) communities stability were the lowest, but showed different community stability values according to the presence of water. It is confirmed that the eco-friendly restoration projects indeed provided the better environment for the inhabitation of benthic macroinvertebrate community. The change of community index depending on the restoration projects suggests that the eco-friendly restoration can provide a more suitable environment for benthic macroinvertebrate ecosystem that prefers the stream environment.

Randomized, Double-blind, and Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Allium Fistulosum L. Root Extract on Improvement of Child Height Growth: Study Protocol (총백추출물의 어린이 키 성장에 대한 유효성 및 안전성을 평가하기 위한 무작위배정, 이중눈가림, 위약 대조 인체적용시험: 인체적용시험 프로토콜)

  • Shim, Soo Bo;Ko, Byoung Seob;Ryuk, Jin Ah;Lee, Jung Hwan;Lee, Ho Bong;Ha, Ki Chan;Kim, Yeung Mi;Lee, Hye Lim
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.2
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    • pp.11-20
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    • 2021
  • Objectives The purpose of the study is to evaluate the safety of the Allium Fistulosum extract in children and its effectiveness in height growth. Methods This study is randomized, double-blind, placebo-controlled trial. The participants are children between the 3rd and 25th percentiles in height, and between the ages of 5 and 12 years. They are randomly assigned to treatment group or control group. The treatment group will take 5 g (1 g as Allium Fistulosum extract) for 24 weeks, 1 time a day. The control group will take the 5 g (0 g as Allium Fistulosum extract) of placebo for 24 weeks, 1 time a day. The primary outcome is change in height, and the secondary outcomes are growth rate, height standard deviations, Insulin-like growth factor-1 (IGF-1), Insulin-like growth factor binding protein-3 (IGFBP-3), IGF1-1/IGFBP-3 ratio, growth hormone, bone age, osteocalcin, and Z-score for growth. Results This protocol has been approved by the institutional review board (IRB) of Daejeon Korean Medicine Hospital of Daejeon University (IRB No. DJDSKH-20-BM-15), and registered in the Clinical Research Information Service (CRIS) (Registry No. KCT0005981). Conclusions This study will provide clinical information about the effectiveness and safety of Allium Fistulosum extract in children for their growth.

Maximizing WSQ Compression Rate by Considering Fingerprint Image Quality (지문 영상 품질을 고려한 WSQ 최대 압축)

  • Hong, Seung-Woo;Lee, Sung-Ju;Chung, Yong-Wha;Choi, Woo-Yong;Moon, Dae-Sung;Moon, Ki-Young;Jin, Chang-Long;Kim, Hak-Il
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.20 no.3
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    • pp.23-30
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    • 2010
  • Compression techniques can be applied to large-scale fingerprint systems to store or transmit fingerprint data efficiently. In this paper, we investigate the effects of FBI WSQ fingerprint image compression on the performance of a fingerprint verification system using multiple linear regressions. We propose a maximum compression using fingerprint image quality score. Based on the experiments, we can confirm that the proposed approach can compress the fingerprint images up to 3 times more than the fixed compression ratio without significant degradation of the verification accuracy.

Analysis of Prevalence of Anemia according to Severity of Atopic Dermatitis (아토피 피부염 심각도에 따른 빈혈 유병률 비교 분석)

  • Yun, Dai;Chang, Ji-Eun;Rhew, Kiyon
    • Korean Journal of Clinical Pharmacy
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    • v.30 no.4
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    • pp.264-269
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    • 2020
  • Background: Inflammatory diseases can increase the prevalence of anemia. Recent studies confirmed that the prevalence of anemia is increased by atopic dermatitis (AD), a chronic inflammatory disease. Therefore, we aimed to elucidate the correlation between AD severity and prevalence of anemia. Methods: We used data of pediatric patients from the Health Insurance Review and Assessment Service (HIRA-PPS-2016). We included pediatric patients (<18 years) with AD diagnosis who were prescribed medications for AD. We applied a propensity score method with inverse probability of treatment weighting (IPTW) adjusting for differences in prevalence of confounders and performed IPTW logistic regression to evaluate associations between the anemia and severity of AD. Results: In total, 91,501 patients (mild AD: 47,054 patients; moderate-to-severe AD: 44,447 patients) <18 years who were prescribed drugs for AD were analyzed. Analysis of the probability of patients with mild AD and prevalence of anemia as a reference revealed an odds ratio (OR) of 1.159 (95% CI, 1.109-1.212; p<0.001) in moderate-to-severe AD patients, indicating a correlation between anemia prevalence and AD severity. Subgroup analysis according to gender, age group, and type of health insurance revealed there was an association between AD severity and anemia except in patients equal or older than 7 years. Conclusion: The prevalence of anemia increased with AD severity despite adjusting for confounding factors. Our results support the hypothesis that AD can cause anemia, and anemia prevalence could be increased in severe AD patients. Further studies are needed to establish a pathological basis.

An empirical study on the impact of intellectual property rights on the management performance of companies: focusing on patent rights (지식재산권이 기업의 경영성과에 미치는 영향에 대한 실증연구: 특허권을 중심으로)

  • Yang, Changyong;Hong, Jung-Wan;You, Yen-Yoo
    • Journal of the Korea Convergence Society
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    • v.12 no.6
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    • pp.173-181
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    • 2021
  • In previous research, large companies were analyzed to focus on their past management performance and patent rights, but in this study we looked at the variability in future sales of small and medium-sized enterprises with patents through empirical analysis. We looked at how the quantitative and qualitative value of patent rights affect management performance of company. We used 'the number of patents' as the quantitative value of patents, 'the average score of patents' as the qualitative value of patents, and the average sales growth rate as the management performance of company. Through a discriminant analysis using the statistical program SPSS, both independent variables used in this study were significant for distinguishing between companies with an average growth in sales more than twice that of general small and medium-sized enterprises and those with less than twice the average sales growth rate. Therefore it is meaningful to provide stakeholders with an analysis framework on how sales will change in the future using the results of this study during guarantee or loan screening for small and medium-sized enterprises with patent rights.

Relationship Between Shift Intensity and Insomnia Among Hospital Nurses in Korea: A Cross-sectional Study

  • Chung, Yuhjin;Kim, Hyunjoo;Koh, Dong-Hee;Park, Ju-Hyun;Yoon, Seohyun
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.1
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    • pp.46-54
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    • 2021
  • Objectives: This study explored the relationship between shift intensity and insomnia among hospital nurses. Methods: The participants were 386 female hospital nurses who underwent a special health examination for night workers in 2015. The Korean Insomnia Severity Index (ISI), indices of shift work intensity, and other covariates such as amount of exercise, level of alcohol consumption, employment duration, and hours worked were extracted from the health examination data. The indices for shift intensity were (1) number of 3 consecutive night shifts and (2) number of short recovery periods after a previous shift, both assessed over the prior 3 months. Multiple logistic regression analysis adjusted for the aforementioned covariates was performed to evaluate the association of shift intensity with insomnia, defined as an ISI score of ≥8. Results: The nurses with insomnia tended to be younger (p=0.029), to have worked 3 consecutive night shifts more frequently (p<0.001), to have experienced a greater number of short recovery periods after the previous shift (p=0.021), and to have worked for more hours (p=0.006) than the nurses without insomnia. Among the other variables, no statistically significant differences between groups were observed. Experiences of 3 or more consecutive night shifts (odds ratio [OR], 2.33; 95% confidence interval [CI], 1.29 to 4.20) and 3 or more short recovery periods (OR, 2.01; 95% CI, 1.08 to 3.73) were associated with increased odds of insomnia. Conclusions: The results suggest that decreasing the shift intensity may reduce insomnia among hospital nurses working rotating shifts.

A Study on the Correlation between Locomotive Syndrome and Stress and Lifestyle Patterns in the Elderly in Korea (국내 노인의 운동기능저하증후군과 스트레스 및 일상생활패턴과의 상관성 분석 연구)

  • Kim, Myungchul;Kim, Haein;Baek, Incheol
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.4
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    • pp.241-251
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    • 2020
  • Purpose : This study examined the effect of locomotive syndrome on stress index and lifestyle patterns among elderly Koreans aged 65 years and older, and analyzed its correlation with stress index and lifestyle patterns. The purpose of this study was to provide basic data for the management and prevention of locomotive syndrome in the elderly. Methods : Using the "25-Question Geriatric Locomotive Function Scale (GLFS-25)", the study evaluated locomotive syndrome in 123 elderly Koreans aged 65 years and older. Of them, 85 patients were assigned to the locomotive syndrome group and 38 patients were assigned to the normal group. The questionnaire measured and investigated the participants' stress index and lifestyle patterns. Statistical analysis was performed using SPSS 22.0 ver. Results : Results showed the locomotive syndrome group displayed a higher stress index than the normal group, with a statistically significant difference between the two groups. The group also scored lower in the lifestyle pattern survey than the normal group did, with a statistically significant difference in high-intensity work performance ratio and average daily performance time between them. The GLFS-25 score showed a significant positive correlation with the stress index and sitting and lying down time, and a significant negative correlation with medium-intensity working time, walking, and cycling time. Conclusion : In conclusion, Locomotive syndrome in elderly Koreans is closely related to stress and lifestyle patterns, especially high-intensity work. We recommend active prevention and management of locomotive syndrome and further research into the effects of various lifestyle factors on the illness.