• Korean Journal of Acupuncture
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• v.24 no.4
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• pp.221-231
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• 2007

목 적 : 본 연구의 목적은 시상하부에서 침처치에 대한 nitric oxide synthase (NOS)발현을 nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d)를 이용한 조직화학 염색법으로 관찰하였다. 실험방법 : 동물은 Balb/c (wild type) 와 Stat 4 knockout (KO) 생쥐를 사용하였다. 염증유도는 1% carrageenan 용액 (20ul/마리)을 발 뒤꿈치 표피에 주사하였고, 침 처치는 족삼리 (ST36)에 시침하였다. 침 처치 후 5시간까지 부종율을 부종측정기로 측정하였으며, 마지막으로 부종을 측정한 후 동물을 희생하여 뇌를 적출하여 고정하였다. 침에 대한 효과를 확인하기 위하여 NADPH-d 반응의 조직염색을 실시하였다. 염증유도와 그룹간의 유의성 검증은 one-way ANOVA를 사용하였다. 결 과 : 대조군인 Balb/c와 실험군인 stat4 KO 생쥐를 carrageenan으로 염증을 유도시에 대조군은 90%이상 유도된 반면, Stat4 KO 그룹은 50% 정도의 염증만이 유도되었다. 염증을 유도한 생쥐의 족삼리에 침 처치시 대조군은 1시간에서 약 40%정도 감소하였고 (P<0.05), Stat4 KO 실험군은 유의한 염증 감소율을 보이지 않았다. 시상하부의 lateral hypothalamic area (LHA)와 paraventricular nucleus (PVN)부위의 침에 대한 효과를 NADPH-d 에 양성으로 반응하는 세포수로 비교하여 다음과 같은 결과를 얻었다. (1) 대조군에서 염증 유도시 시상하부의 PVN는 NADPH-d 양성세포수가 감소하였고, LHA에서는 증가하였다. (2) 염증을 유도한 대조군에 침을 처치시 PVN은 세포수가 증가하였고, LHA에서는 감소하는 경향을 보였다. (3) 염증을 유도한 Stat4 KO 군에서는 시상하부의 PVN과 LHA부위 모두에서 NADPH-d 양성세포수가 감소하였고, 염증유도그룹에 침을 처치시 PVN과 LHA부위 모두에서 세포수가 증가함을 관찰 할 수 있었다. (4) 대조군과 실험군 모두에 salicylic acid로 비교하였더니 염증유도 효과 및 NADPH-d 세포 수에서 침 처치와 비슷한 결과를 나타내었다. 결 론 : 침은 염증을 유도한 생쥐에서 염증 감소에 유의한 효과가 있다. 염증을 유도한 Balb/c 와 Stat4 KO 생쥐에 침을 처치 시 시상하부의 NADPH-d 발현이 LHA부위와 PVN에서 서로 다르게 나타나는 것으로 나타난다. 이러한 현상은 침 효과가 시상하부의 위치에 대한 작용이 다르기 때문이라고 생각된다.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.5 no.2
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• pp.128-136
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• 1995

The purpose of this study is to evaluate the difference of noise level according to noise measuring methods in the noisy working environments. Sound pressure level(SPL), equivalence sound level(Leq) and personal noise exposure dose(Dose) in the fifty-nine unit workplaces of the twenty-eight industries were measured and relating factors which were affected noise level were investigated. The results were as follows ; 1. The noise levels were $88.70{\pm}5.68dB(A)$ by SPL, $89.07{\pm}5.41dB(A)$ by Leq and $89.07{\pm}5.69$ by Dose. The differences of noise levels by three measuring methods were statistically significant(P<0.001) by repeated measure ANOV A. 2. Comparing with noise levels by general classes of noise exposure, noise levels of continuous noise were $89.14{\pm}5.19dB(A)$ by SPL, $89.45{\pm}4.65dB(A)$ by Leq and $90.04{\pm}5.09$ by Dose. Noise levels of intermittent noise were $87.90{\pm}6.52dB(A)$ by SPL, $88.40{\pm}6.63dB(A)$ by Leq and $90.10{\pm}6.80$ by Dose. The differences noise level of noise measuring methods by general classese of noise exposure were statistically not significant by repeated measure ANOV A. 3. Interaction between general classese of noise exposure and noise measuring methods for noise level was not statistically significant by repeated measure ANOVA. And the noise level by noise measuring methods were statistically significant by repeated measure ANOV A(P<.001) 4. Comparing with noise levels by unit workplace size, noise levels of large unit workplace were $90.73{\pm}5.87dB(A)$ by SPL, $91.32{\pm}5.50dB(A)$ by Leq and $91.82{\pm}6.06$ by Dose and noise levels of middle unit workplace were $88.31{\pm}5.26dB(A)$ by SPL, $88.41{\pm}4.83dB(A)$ by Leq and $89.69{\pm}5.05$ by Dose. And noise levels of small unit workplace were $94.89{\pm}4.10dB(A)$ by SPL, $85.35{\pm}4.11dB(A)$ by Leq and $86.87{\pm}4.98$ by Dose. The noise level differences of noise measuring methods by unit workplace size were statistically significant by repeated measure ANOV A(P<.05). 5. The noise level by noise measuring methods were statistically significant by repeated measure ANOV A(P<.001). But Interaction between workplace size and noise level measuring methods for noise level was not statistically significant by repeated measure ANOVA. According to the above results, there was a difference of the noise level among the three measuring methods. Therefore we must use the personal noise exposure dose using by noise dose meter, possible, to prvent occupational hearing loss in noisy working environment.

• The korean journal of orthodontics
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• v.40 no.4
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• pp.227-238
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• 2010

Objective: The purpose of this study was to analyze the effect of growth hormone treatment (GHT) on craniofacial growth in children of short stature. Methods: Nineteen untreated children of short stature were referred from the Pediatric Department, Yeungnam University Hospital as a subject group. All subjects had lateral cephalograms taken before, after 1 year and after 2 years of growth hormone treatment. As a reference group, we selected 19 normal children with paired sampling who matched the subjects' age and sex, from the Department of Orthodontics, Kyungpook National University Hospital. Results: Before GHT, anterior cranial base length and upper posterior facial height, posterior total facial height, mandibular ramus length, and mandibular corpus length were significantly smaller in the reference group. In angular craniofacial measurements, saddle angle and mandibular plane angle were larger. SNA and SNB were smaller in the reference group. After two years of GHT, growth hormone accelerated growth in several craniofacial components. The posterior total facial height, the anterior, posterior cranial base length, and the mandibular ramus length were increased. And the difference in mandibular plane angle and ANB values compared with the reference group was decreased. Conclusions: GHT over 2 years leads to a craniofacial catch-up growth tendency, which is pronounced in interstitial cartilage and condylar cartilage.

• Journal of the Korean Society of Food Culture
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• v.17 no.4
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• pp.482-495
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• 2002

Changes in ATP and related compounds, TMAO, TMA, creatine and creatinine were analyzed to establish the processing conditions for rapid- and low salt-fermented liquefaction of anchovy(Engrulis japonica) extracts during fermentation. Experimental sample A: chopped whole anchovy, adding 20% water, heating at $50^{\circ}C$ for 9 hrs and then adding 10% NaCl. Sample B: chopped whole anchovy, adding 20% water, heating at $50^{\circ}C$ for 9 hrs and then adding 13% NaCl. Sample C: chopped whole anchovy adding 13% NaCl. Sample D: whole anchovy adding 17% NaCl. ATP, ADP, AMP and IMP were broken down during fermentation period, while inosine and hypoxanthine or hypoxanthine were detected in each fermented liquefaction of anchovy. However the amounts of them were varied from collection to collection according to the pretreatment methods. Possibly ATP and their related compounds will not make a great contribution to the umami taste in fermented liquefaction of anchovy. The contents of TMAO were decreased during fermentation period, ranging from 3 to 15 mg/100g in the fermented liquefaction of anchovy after 180 days. The TMA contents were increased slowly during fermentation period, ranging from 60 to 114 mg/100g in the 180 days specimens, however their contents were varied from sample to sample. The contents of creatine and creatinine were increased during early fermentation period, and then they were decreased in the last period. As for distribution of nitrogen in the anchovy extracts, the contribution of creatine and creatinine to the extractive nitrogen was occupying 6.8, 5.7, 4.6 and 5.7% in the experimental sample A, B, C and D, respectively. The contribution of ATP and related compounds to the extractive nitrogen was occupying 2.1, 2.4, 2.2 and 2.7% in the experimental sample A, B, C and D, respectively. The contribution of TMAO and TMA to the extractive nitrogen was very low as they are occupying $0.7{\sim}1.2%$ in the four experimental samples.

• Atmosphere
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• v.18 no.3
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• pp.183-197
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• 2008

The purpose of this study is to summarize tropical cyclone activity in 2007. 24 tropical cyclones of tropical storm (TS) intensity or higher formed in the western North Pacific and the South China Sea in 2007. The total number is less than the thirty-year (1971~2000) average frequency of 26.7. Out of twenty four tropical cyclones, 14 TCs reached typhoon (TY) intensity, while the rest 10 only reached severe tropical storm (STS) and tropical storm (TS) intensity - four STS and six TS storms. The tropical cyclone season in 2007 began in April with the formation of KONG-REY (0701). From April to May, two TCs formed in the western North Pacific in response to enhanced convective activity there. From June to July, convective activity turned inactive over the sea around the Philippines and in the South China Sea, and the subtropical high was weak over the south of Japan. MAN-YI (0704) and USAGI (0705) moved northwestward and hit Japan, bringing serious damage to the country. After August, convective activity became enhanced over the sea east of the Philippines, and the subtropical high turned strong over the sea south of Japan. Many TCs, which formed over the sea east of the Philippines and in the South China Sea, moved westward and hit China and Vietnam. PABUK (0706), WUTIP (0707), SEPAT (0708), WIPHA (0712), LEKIMA (0714) and KROSA (0715) brought serious damage to some countries including China, the Philippines and Vietnam. On the other hand, FITOW (0709) and NARI (0711) moved northward, bringing serious damage to Japan and Korea. After HAIYAN (0716), all four TCs except FAXAI (0720) formed over the sea east of $140^{\circ}E$. Three typhoons among them affected Republic of Korea, MAN-YI (0704), USAGI (0705) and NARI (0711). Particularly, NARI (0711) moved northward and made landfall at Goheng Peninsula ($34.5^{\circ}N$, $127.4^{\circ}E$) in 1815 KST 16 September. Due to $11^{th}$ typhoon NARI, strong wind and record-breaking rainfall amount was observed in Jeju Island. It was reported that the daily precipitation was 420.0 mm at Jeju city, Jeju Island on 16 September the highest daily rainfall since Jeju began keeping records in 1927. This typhoon hit the southern part of the Korean peninsula and Jeju Island. 18 people lost their lives, 14,170 people were evacuated and US$ 1.6 billion property damage was occurred.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.46 no.6
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• pp.892-900
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• 2013

In 2011, the system for conserving and managing cetacean resources in Korea changed. The status of the cetacean bycatch was analyzed using a distribution certificate that was issued by the coast guard. During 2011.2012, 12 species were bycatch in Korean waters: three species of baleen whale and nine species of dolphin. The finless porpoise (Neophocaena phocaenoides) was the dominant species, followed by the common dolphin (Delphinus delphis), harbor porpoise (Phocoena phocoena), and Pacific white-sided dolphin (Lagenorhynchus obliquidens). Among the baleen whales, the common minke whale (Balaenoptera bonaerensis) was first and Bryde's (Balaenoptera edeni) and humpback (Megaptera novaeangliae) whales appeared in the Korea Strait and East Sea, respectively. Among the dolphins, the finless porpoise ranked first in the Yellow Sea. The common dolphin, Pacific white-sided dolphin, and harbor porpoise were more frequent in the East Sea than in other waters. The cetacean bycatch was caused mainly by pots, set nets, gill nets, and stow nets. Among the three species of baleen whale, the common minke whale was caught by pots and set nets, and comprised over 68.9% of the total bycatch in 2011 and 56.2% in 2012. Comparing the bycatch caused by fishing gears by area in 2011 and 2012, 97.9% and 99.6%, respectively, of the finless porpoise bycatch in the Yellow Sea was by stow nets. In the Korea Strait, trawl bycatch comprised 67.3% in 2011 and 73.0% in 2012, followed by gill nets, set nets, and pots targeting finless porpoise and common minke whales. In the East Sea, gill nets were responsible for 46.7% in 2011 and 61.2% in 2012, followed by set nets and pots.

• Journal of fish pathology
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• v.24 no.2
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• pp.53-64
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• 2011

In quantitative studies of clinical signs, rock bream of adults and juveniles infected with Megalocytivirus IVS-1 isolated from rock bream (Oplegnathus fasciatus) in Korea showed average $4.49{\pm}1.13$ and $4.85{\pm}1.06$ of spleen index respectively. In challenge experiments, Megalocytivirus IVS-1 induced 100% cumulative mortality in both adult and juvenile rock bream. However we found 60% cumulative mortality in juvenile red sea bream (Pagrus major) even after 30 days of injection, which contradicted with the results of other laboratories. Interestingly, IVS-1 infected red sea bream of the same juvenile size with rock bream showed lower spleen index compared to that of rock bream. In real-time PCR, there was continuous increasing of the numbers of viral copies ($2.03{\times}10^7$ copies/mg) in the spleen of juvenile rock bream infected, which were different from those in adult rock bream showing plateau level after reaching to the peak level. Moreover, enlarged cell numbers in the infected spleen were also increased continuously in the juvenile but not in adult of rock bream, even decreased after reaching to peak level. Consequently, significant differences in clinical signs: cumulative mortality. spleen index and viral copy number were found between rock bream and red sea bream, but not between adult and juvenile rock bream. Certainly quantitative expression of clinical sign as in this study may be a way to compare the progression of megalocitiviral disease more accurately in different species or physiological conditions.

• The Journal of Korean society of community based occupational therapy
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• v.3 no.2
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• pp.1-12
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• 2013

Objective : The objective of this study is to present basic data to find health care plans for the elderly by comparing time-management ability and ADL and identifying the relationships between groups with subjects of elderly people living alone and living with family in Daejeon Metropolitan City. Method : A total of 80 elders who lived alone or with family that were aged 65 or older were selected with MMSE-K, 40 people were selected as subjects for each group. For time-management ability, a questionnaire was used. ADL were assessed by using FIM. The study period was May to June 2013. Result : Comparison of scores for time-management ability and FIM of the elderly who live alone or living with family did not show any statistically significant difference. In comparison of detailed scores between groups, there were statistically significant differences between the two groups being social interaction, problem solving and memory in social cognition items among detailed items. Conclusion : Through this study, we understood that social cognitive function of the aged living alone who had less opportunity of interaction compared to that of the aged living with family was lowered. Based on this, development and study on various programs should be made with consideration of sociodemographic characteristics of the elderly within community-based occupational therapy in the future.

• Culinary science and hospitality research
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• v.19 no.4
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• pp.1-12
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• 2013

The purpose of this study was to find the effects of guava leaf powder as a natural tenderizing ingredient for low-fat pork seasoned with meat sauce, and to promote a consumer demand and practical use of low-fat pork. Moisture content, pH, color, texture, and sensory tests (quantitative descriptive sensory evaluations and acceptance) were conducted to the control and 5 samples of pork seasoned with 0.75, 1, 1.5, 2, 3% guava leaf powder) to determine the highest effectiveness on tenderizing pork. Moisture content and pH values were the highest in the samples with 1% and 1.5% of guava leaf powder added. L-value of cooked meat decreased, while a-value increased. In the texture test, most of the experiments showed the best values in the sample with 1.5% added. Based on quantitative descriptive sensory evaluations, the unpleasant smell of meat tended to decrease with more guava leaf powder, and the scores of the others were highest in the sample with 1.5% added. This sample also got the highest score in the acceptance test. These results can be used as primary data for research on the tenderizing effect of a functional ingredient and solutions to unbalanced consumption of pork.

• Journal of Periodontal and Implant Science
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• v.37 no.1
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• pp.65-75
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• 2007

In this study, author examined the effect of the concentration of the inorganic polyphosphate on the process of the bone regeneration by using the 6 weeks old rabbit with the weight of 2.0kg in average. we performed the experiment by using TR-eITFE membrane filled with collagen immersed with 1%, 2%, and 4% of inorganic polyphosphate, respectively, after removing the proper sized cort-ical bones from the calvaria of rabbit. The experimental results were compared with the one of the following four groups: The control group for membrane only, experimental group I for membrane filled with collagen im-mersed with 1% of inorganic polyphosphate, experimental group II for membrane filled with collagen immerse with 2% of inorganic polyphosphate, experimental group III for membrane filled with colla-gen immersed with 4% of inorganic polyphosphate. The fragments of the tissue with membrane were obtained from each group of the sacrificed rab-bits for 4 or 8 weeks sustained after surgery, were then prestained and coated. New bone formation was assessed by histomorphometric and statistical analysis. We may draw the conclusions from these experiments as following: 1. Collagen was an excellent carrier with a minimal inflammatory reaction and sustaining the form. 2. The sample of the 8th week group has shown the best bone regeneration compared with the cases of all groups including the control group. 3. The samples of collagen immersed with 2% and 4% of inorganic polyphosphate have shown more bone regeneration relative to the sample of the 1% inorganic polyphosphate. 4. The new bone regeneration was shown actively in the group for membrane filled with collagen immersed with 4% of inorganic polyphosphate. With above results, it is strongly suggested the use of inorganic polyphosphate with vehicle under TR-eITFE membrane.