• Title/Summary/Keyword: Science and Engineering

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Growth Performance and Meat Quality of Broiler Chickens Supplemented with Bacillus licheniformis in Drinking Water

  • Liu, Xiaolu;Yan, Hai;Lv, Le;Xu, Qianqian;Yin, Chunhua;Zhang, Keyi;Wang, Pei;Hu, Jiye
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.5
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    • pp.682-689
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    • 2012
  • A feeding trial was conducted to investigate effects of Bacillus licheniformis on growth performance and meat quality of broilers. Nine hundred one-d-old broiler chicks were randomly assigned to 3 experimental groups with three replicate pens of 100 broiler chicks. Three treatments were i) control, ii) basal diets supplemented with 1 ml of B. licheniformis for each in feed water per day iii) basal diets supplemented with 2 ml of B. licheniformis per chick in feed water per day. The supplementation of B. licheniformis significantly increased body weight in grower chickens (p<0.05), and significantly improved the feed conversion in 3 to 6 and 0 to 6 wk feeding period compared with the control group (p<0.05). Additionally, the supplement also resulted in increased protein and free amino acid contents, and decreased fat content in chicken breast fillet (p<0.05). Furthermore, improvement in sensory attributes was observed in broilers fed with the probiotic. In conclusion, B. licheniformis treatments resulted in a significant increase (p<0.05) in broiler productivity based on an index taking into account daily weight gain and feed conversion rate. Meanwhile, the probiotic contributed towards an improvement of the chemical, nutritional and sensorial characteristics of breast fillet. Overall, the study indicates that B. licheniformis can be used as a growth promoter and meat quality enhancer in broiler poultry.

Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson's disease

  • Yoo, Hajung;Lee, Jeongmin;Kim, Bokwang;Moon, Heechang;Jeong, Huisu;Lee, Kyungmi;Song, Woo Jeung;Hur, Junho K.;Oh, Yohan
    • BMB Reports
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    • v.55 no.7
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    • pp.323-335
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    • 2022
  • Together with neuronal loss, the existence of insoluble inclusions of alpha-synuclein (α-syn) in the brain is widely accepted as a hallmark of synucleinopathies including Parkinson's disease (PD), multiple system atrophy, and dementia with Lewy body. Because the α-syn aggregates are deeply involved in the pathogenesis, there have been many attempts to demonstrate the mechanism of the aggregation and its potential causative factors including post-translational modifications (PTMs). Although no concrete conclusions have been made based on the previous study results, growing evidence suggests that modifications such as phosphorylation and ubiquitination can alter α-syn characteristics to have certain effects on the aggregation process in PD; either facilitating or inhibiting fibrillization. In the present work, we reviewed studies showing the significant impacts of PTMs on α-syn aggregation. Furthermore, the PTMs modulating α-syn aggregation-induced cell death have been discussed.

Measurement and removal of a cerenkov light in a plastic optical fiber to detect a scintillating light (섬광검출을 위한 플라스틱광섬유에서의 체렌코프 빛 측정 및 제거)

  • Cho, Dong-Hyun;Jang, Kyoung-Won;Yoo, Wook-Jae;Shin, Sang-Hun;Lee, Bong-So;Park, Byung-Gi;Cho, Hyo-Sung;Kim, Sin
    • Journal of Sensor Science and Technology
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    • v.17 no.2
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    • pp.100-105
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    • 2008
  • The objectives of this study are to measure and to remove Cerenkov lights generated in a fiber-optic radiation sensor by a charge-coupled device. we have fabricated a fiber-optic radiation sensor which comprises an organic scintillator, a plastic optical fiber and a charge-coupled device. Charge-coupled device as a light measuring tool has many advantages which are easy in multi-dimensional measurements, high spatial resolution and relatively low cost.