• 한국환경농학회지
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• 제39권2호
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• pp.122-129
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• 2020

BACKGROUND: Dissipation patterns of insecticides (acequinocyl, clothianidin, diflubenzuron, thiacloprid, and thiamethoxam) on strawberry grown in plastic-covered greenhouse were evaluated at 7 intervals including the preharvest interval after application. This study was performed to determine the residue concentrations, half-lives and dissipation rates in strawberry for the harvest periods. METHODS AND RESULTS: Acequinocyl, clothianidin, diflubenzuron, thiacloprid, and thiamethoxam were applied in accordance with critical good agricultural practices for strawberry. Strawberry samples were collected at 0, 1, 2, 3, 5, 7 and 10 days after application. Quantitaion was performed by HPLC/DAD and HPLC-MSMS system with C₁₈ column. The limit of quantitation (LOQ) values varied between were 0.00025~0.05 mg/kg on strawberry. The recoveries of acequinocyl, clothianidin, diflubenzuron, thiacloprid and thiamethoxam at two concentrations ranged from 70.9~104.9% on strawberry. The half-lives of pesticide dissipation on strawberry for two fields ranged from 1.3~8.2 days. The dissipation rates were evaluated according to the statistics method with a 95% confidence. CONCLUSION: The residue levels of insecticides (acequinocyl, clothianidin, diflubenzuron, thiacloprid, and thiamethoxam) on strawberry at 0-day after application were below the specified values by Korean MRL. To estimate dissipation rate constant of pesticides on crop for harvest periods, it is important to set the pre-harvest residue limit for human health and consumer protection in Korea.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권1호
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• pp.31-37
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• 2016

Objectives: The aim of the present study was to evaluate changes in the management and 5-year survival rates of patients with oral cancer in our department over a 30-year period. Materials and Methods: We investigated the patient distributions, treatment methods, method of neck dissection according to cancer stage, and 5-year survival rates for 700 oral cancer patients over the periods of 1982-1996 (256 patients), 1999-2006 (248 patients), and 2007-2011 (196 patients). Results: Stage IV patients were the largest group in all of the time periods evaluated. Although surgery and radiotherapy were the most common methods in all periods (over 50%), the prevalence of patients who underwent concomitant chemoradiotherapy increased from 7.0% to 16.2%. The use of radical neck dissection decreased from 43.0% to 5.3%, while conservative surgical methods increased from 24.1% to 76.3%. Lastly, the overall 5-year survival rate increased from 31.6% to 63.5% during the study period. Conclusion: Although the 5-year survival rate reached the same level as that of other developed countries during the course of our study, most patients continue to come to the hospital with stage IV disease. In order to increase the 5-year survival rate of oral carcinoma, it may be necessary to improve public education and social efforts relevant to early diagnosis.

• The Journal of Advanced Prosthodontics
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• 제14권3호
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• pp.133-142
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• 2022

PURPOSE. A large number of studies have suggested the practicability and predictability of immediate implant function, but few studies have reported marginal bone level changes during sequential loading periods. The purpose of this study was to evaluate the marginal bone remodeling of immediately loaded self-tapping implants both at each time point and during each loading period between two time points. MATERIALS AND METHODS. The patients included in this retrospective study were treated with immediately loaded NobelSpeedy Replace implants between August 2008 and July 2009. Differences in the marginal bone level (MBL) at each time point and the marginal bone level change (ΔMBL) between two time points were analyzed with Bonferroni correction (P < .05). RESULTS. Overall, 24 patients (mean age, 47.3 ± 12.8 years) with 42 immediately loaded implants and a median follow-up of 6.5 years (IQR, 67.8 months) were included. The cumulative survival rate after 10 - 12 years was 95.2%. Continuous but slow marginal bone loss was observed during long-term follow-up. MBL at both 7.5 years and 11 years was significantly lower than that at loading, 6 months, 2 years and 4 years (P < .05). No bone loss difference was found in any period before 4 years of follow up (P > .05). The loading period of 4 years to 7.5 years showed the largest ΔMBL compared to those of other time periods (P < .05). CONCLUSION. Slight bone loss occurred continuously, and more radical changes of marginal bone can be observed during the period of 4-7.5 years. Thus, long-term effective follow-up of immediately loaded implants is needed.

• The Journal of Korean Physical Therapy
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• 제35권4호
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• pp.95-104
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• 2023

Purpose: This study was undertaken to identify the effects of apparatus Pilates exercise on Cobb's angle, angle of trunk rotation, and depression in female patients with idiopathic scoliosis. Methods: Participants included five patients with idiopathic scoliosis presenting with Cobb's angle of 10 degrees or more. Among the single-subject experimental research designs, the reversal (ABA) design was selected and performed. The apparatus Pilates exercise was performed for a total of 16 weeks, comprising 8 weeks between the baseline and intervention 1 period and 8 weeks between intervention 1 and intervention 2 periods. The patients were then followed up for 5 weeks. Results: In all subjects, compared to the baseline, Cobb's angle and the angle of trunk rotation decreased after application of the apparatus Pilates exercise. The follow-up period also showed a similar continuous decline. Following the apparatus Pilates exercise, the depression scale in subject 3 was increased during the intervention 1 period as compared to the baseline. However, the patient displayed a reduced depression scale in intervention 2 and follow-up periods. The depression scale in all other subjects was decreased for both intervention periods and the follow-up period. Conclusion: The application of apparatus Pilates exercise improves Cobb's angle and the angle of trunk rotation for female patients with idiopathic scoliosis in their 10s and 20s. Our results also indicate that this is potentially an effective intervention method to overcome depression.

• Molecular & Cellular Toxicology
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• 제4권4호
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• pp.278-284
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• 2008

The X-linked inhibitor of apoptosis (XIAP) is a member of a novel family of inhibitors of apoptosis and has several BIR domains (BIR1, BIR2, and BIR3) and a carboxy-terminal RING zinc-finger. Since suppressionof apoptosis is fundamentally important for carcinogenesis and tumor growth, we investigated the expression and function of XIAP in DEN-induced carcinogenesis using rat model. Wistar rats were injected intraperitoneally with DEN at a dose of 50 mg/kg in twice a week for 12 weeks (Group II) and 16 weeks (Group III) followed by the recovery periods, respectively. The evaluation of DEN-induced carcinogenesis carried out the blood, RT-PCR, histopathological and western blot analysis. The level of blood chemistry including GOT/GPT, albumin, and total bilirubin were significantly exchanged comparing to control and Group I/Group II. The expression of albumin and collagen mRNA were significantly exchanged (P<0.05) in both groups. In addition, AFP mRNA expression decreased more after recovery periods than Group II. XIAP was expressed constitutively in normal rat liver as well as DEN-induced Groups I and Group II. In addition, XIAP expression increased more in Group I with 4 weeks recovery periods than Group I. However, XIAP expression shown to increase in Group lI, otherwise, it was decreased in Group II with 10 weeks repair periods. Taken together, these results suggest the alteration of XIAP expression could be involved in hepatocellular carcinogenesis.

• 천문학회보
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• 제40권1호
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• pp.66.1-66.1
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• 2015

We present the first observational detection of radial and azimuthal oscillations in full halo coronal mass ejections (HCMEs). We analyze nine HCMEs well-observed by LASCO from Feb 2011 to Jun 2011. Using the LASCO C3 running difference images, we estimated the instantaneous apparent speeds of the HCMEs in different radial directions from the solar disk center. We find that the development of all these HCMEs is accompanied with quasi-periodic variations of the instantaneous radial velocity with the periods ranging from 24 to 48 mins. The amplitudes of the instant speed variations reach about a half of the projected speeds. The amplitudes are found to anti-correlate with the periods and correlate with the HCME speed, indicating the nonlinear nature of the process. The oscillations have a clear azimuthal structure in the heliocentric polar coordinate system. The oscillations in seven events are found to be associated with distinct azimuthal wave modes with the azimuthal wave number m=1 for six events and m=2 for one event. The polarization of the oscillations in these seven HCMEs is broadly consistent with those of their position angles with the mean difference of $42.5^{\circ}$. The oscillations may be connected with natural oscillations of the plasmoids around a dynamical equilibrium, or self-oscillatory processes, e.g. the periodic shedding of Alfvenic vortices. Our results indicate the need for advanced theory of oscillatory processes in CMEs.

• 한국항행학회논문지
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• 제17권1호
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• pp.90-97
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• 2013

최근 영상처리 기법에 기반한 지능형 교통시스템의 개발이 활성화되고 있다. 본 논문에서는 도심 사거리에서 획득한 비디오를 분석하여 차량의 움직임 변화와 체류시간에 기반한 추돌 검출 알고리즘을 제안한다. 가우시안 혼합 모델 기반으로 생성된 배경과 입력영상의 차 영상으로부터 관심영역(ROI)안의 객체를 추출한다. 추출된 객체에 대해 계산된 움직임벡터와 화면 내 차량 체류시간을 이용하여 교차로 내 차량추돌과 교통체증을 검출하였다. 제안된 알고리즘은 추돌을 포함한 실제 교차로 영상에 대해 테스트되었고, 탐지율은 85.7%이고, 오탐율은 7.7%였다.

• International Journal of Oral Biology
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• 제40권3호
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• pp.127-133
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• 2015

The salivary gland undergoes complex process of growth and differentiation of the branching morphogenesis of ductal system during the prenatal and early postnatal periods which are regulated by various elements in the extracellular matrix. Extracellular matrix metalloproteinase inducer (EMMPRIN) is a cell adhesion molecule. In the present study, localization and expression of EMMPRIN in development and effects of chorda-lingual denervation and cyclosporine A (CsA) treatment on the EMMPRIN expression were investigated. Immunohistochemistry, RT-PCR and Western blot were used to determine expression level. Immunohistochemistry revealed that EMMPRIN was localized specifically in the cytoplasm of ductal cells, not acini of the submandibular gland all the postnatal periods. At prenatal day 18, when the formation of ducts was not definite, no immunoreactivity was observed. Both Western blot and RT-PCR analyses revealed that EMMPRIN expression was maintained up to postnatal day 7, decreased after postnatal day 10. The EMMPRIN expression was upregulated by the surgical denervation of the chorda-lingual nerve in the gland as well as by the CsA treatment. The present study suggests that EMMPRIN is a crucial molecule for maintaining physiological functions of the salivary gland.

• Asia Marketing Journal
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• 제18권3호
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• pp.1-18
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• 2016

The purpose of this paper is to examine empirically how to balance advertising expenditure before and after launch with regard to the direction of word of mouth in the motion picture industry. The vector auto-regression model is applied to assess the dynamic impact of advertising and word of mouth on sales. Empirical data, including advertising, word of mouth, and sales (the number of entries) of 83 movies are used for analysis. The research results show that for a movie having more positive word of mouth in the pre- and post-launch periods, it is worthwhile to spend the advertising budget in the pre-launch period only and to spare it in post-launch period. However, it is worthwhile to spare the advertising budget in the pre-launch period for movies having less positive word of mouth before and after launch, and to concentrate spending in post-launch period instead. Mangers who handle products and services facing shortened lifecycles, such as games, eBooks, and digital music contents, need to check the quality of pre-launch word of mouth for their advertising budget decisions in the pre- and post-launch periods and spend more of the advertising budget in the post- (pre-) launch period if pre-launch word of mouth is negative (positive). For products and services with a shortened lifecycle, it is recommended to spend more of the advertising budget in the post- (pre-) launch period if pre-launch word of mouth is negative (positive).

• 한국수학교육학회지시리즈A:수학교육
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• 제37권1호
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• pp.87-99
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• 1998

Mathematics education is very important in future because mathematics is the basis of every study, for example, natural and social science, etc. Our nation wide curriculum has been revised six times since 1948. In 1992, the sixth revision was enforced and we are using the revised textbook now. This study aims at helping of continuous investigation for educational curriculum and textbook, and aims at efficient teaching by preventing unnecessary repetition and excessive gap in real field by analyzing the articulation of Analytics part in school textbook from elementary to high school. This thesis consists of the followings. 1.Investigation of the principles and natures of articulation along with curriculum course and notice the articulation based on the analysing tools. 2.Importance of learning functions. 3.To get the propriety, formation of 8 judging group and classification of content materials in function chapters by the judges based on the analyzing tools. 4.Analysis of presentation method and terminologies in the first concepts, suggestion teaching method to reduce gap and help of understanding on first concepts in the study of function. As a result 'development' consists of 55.8% of the total and it is higher than 'duplication' and 'gap'. To be specific in periods, between elementary school and middle school 'development' takes 64.5% and this shows an acceptable articulation in the period. While 39.4% of 'gap' in articulation between middle school and high school looks high compared with 'gap' between the previous periods. The item suggested with the 'gap' is the 'definition of function', 'value of function', 'parallel translation', 'exponential and logarithmic function'. It is observed that these materials is suddenly appeared in high school.