• 생명과학회지
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• 제17권8호통권88호
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• pp.1121-1128
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• 2007

초피나무(Z. piperitum) 열매는 다양한 생리활성을 갖고 있으며, 과피 용매추출물은 세균에 대한 강한 항균활성을 갖고 있어, 간장과 된장제조에 초피를 첨가하여 생리활성효과를 조사하였다. 초피를 간장제조에 1%, 2%, 4% 첨가하여 제조하고, 간장추출물을 식중독균(Sta. aureus, Sal. typhimurium, V. parahemolyticus, E. coli 0157:H7)에 대한 항균활성을 조사했다. 초피를 2% 첨가한 간장은 E. coli 0157:H7과 V. parahemolyticuS 의 생육을 각각 70%와 50% 억제했으며, Sal. typhimurium 과 Sta. aureus 에 대한 항균효과는 농도와 간장제조시기에 따라 40% ${\sim}$ 60% 의 생육을 억제했다. 초피된장의 용매추출물에서는 약한 항균활성을 확인할 수 있었다. 초피간장의 추출물을 백혈병세포 U-937에 처리하여 caspase-3 활성으로 항암활성을 조사했다. 그 결과 초피의 량을 1%, 2%, 4% 첨가한 간장의 추출물은 초피를 침가하지 않은 간장보다 caspase-3 활성이 각각 4배, 12배, 15배 활성이 증가하는 것이 확인되어졌다. 이는 초피간장의 추출물이 apoptosis를 유도하는 것을 의미하며, 된장의 용매추출물은 caspase-3 활성에 아무런 영향이 없었다. 초피간장 추출물을 처리한 세포의 죽음이 necrosis인지 apoptosis인지 알아보기 위하여 세포내의 DNA fragmentation을 확인한 결과, 초피간장 추출물을 처리한 세포는 DNA 단편화가 형성되어졌다. 초피틀 1% 첨가한 것에서는 fragmentation을 확인하기 힘들었고, 2%와 4%초피를 첨가한 간장추출물은 DNA fragmentation을 강하게 일으켰다. 초피를 첨가한 간장추출물이 caspase를 활성화시키고, DNA fragmentation을 일으키는 apoptosis 기작에 의해 암세포를 죽음으로 유도하는 초피간장의 항암효과를 입증했다.

• 한국철학논집
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• 제32호
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• pp.113-159
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• 2011

17세기 중 후반에 진행된 서인의 자기 분열과 소론계의 출현은 조선사회 내부에서의 일대 정치사적 사건에 해당하는 의미를 내포한다. 이제 소론은 송시열이 역학 구도의 원천에 배치된 노론과는 상이한 사상적 대외적 노선을 구축해 나가게 됨으로써, 척박한 조선 지성계의 면모를 일신할만한 한 축을 형성하게 되었다. 실상 이러한 조짐은 노소 분열이 진행되는 과정에서 윤선거가 시종 윤휴의 사상성을 변호하고, 이른바 회니 시비의 와중에서 윤증이 송시열의 위선적 학문 행위와 명분론적 대외 노선을 동시에 비판할 때에, 이미 그 맹아가 움트기 시작했던 것이다. 초기 소론을 대표하는 윤증과 박세당, 남구만과 박세채 등은 실로 다양한 사안들을 대상으로 한 토론과 대화 문화를 존중함으로써, 장차 소론계만의 고유한 학풍을 형성하는 데 크게 기여했다. 소론의 중진들은 당면한 시국 현안에 대해서도 폭넓은 대화와 토의를 병행해 나갔던바, 박세채가 집성한 황극탕평론은 정치철학적 영역에서 소론계의 대화 문화가 결실한 또 하나의 긍정적인 사례였다. 소론의 선배들은 붕당의 폐해를 타파하기 위한 논의인 탕평론에 깊이 공감하고, 그 기본 골격을 형성해 나가는 과정에서 상호간의 의견을 폭넓게 참작했던 것이다. 결과적으로 초기 소론의 선배들은 닫힌 동일성의 학문적 울타리에 안주하기보다는 서로의 차이를 존중하는 대화 양식을 존중함으로써, 진정한 학문적 행위란 소통을 지향하는 과정을 통해서만이 유의미한 결실을 맞이한다는 사실을 과시해 보였던 것이다. 이처럼 대화와 토론을 통한 소통적 학문 행위는 소론의 2세대에게로 전승되면서, 장차 소론계만의 고유한 학풍으로 정착될 국면을 맞이할 전망이다.

• 농업과학연구
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• 제38권2호
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• pp.349-360
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• 2011

The international oil price have being fluctuated due to the exhaustion of fossil energy problem became big social issue. Rural villages are relatively sensitive to the energy problem, reflecting the characteristics of rural sustainable and stable introduction of renewable energy sources that are available is essential. In addition, through the influx of young workers in rural areas to regain vitality, efforts to improve rural living environment has been under the rural newtown project. In this study, a survey aimed at rural dwellers through the AHP, interview to report of realization about renewable energy and review the current policies. The results of realization survey though AHP are as follows, (1) the advantage of the natural environment (2) the superiority of government supporting policy and being economic, (3) easy to use, (4) ecologically stable, and (5) policy stable, respectively. In addition, renewable energy sources among the inhabitants of rural areas by solar energy was the highest score. The impact of regional characteristics compared with other energy sources receive little, easy to apply and has already been considerable technological development is considered.

• The Journal of Advanced Prosthodontics
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• 제10권1호
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• pp.18-24
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• 2018

PURPOSE. In literature, many studies compare survival rates of different types of FPDs. Most of them compared restorations, which originated from one university, but from different clinicians. Data about restoration survival rates by only one experienced dentist are very rare. The aim of this study was to evaluate the survival rate of all-ceramic FPDs without the blurring effects of different clinicians. MATERIALS AND METHODS. 153 veneered-zirconia FPDs were observed for follow-up. 22 patients received 131 single crowns and 22 bridges. Because of the different bridge lengths, one unit was defined as a restored or replaced tooth. In total, 201 units were included. Only the restorations performed by the same clinician and produced in the same dental laboratory from 2011 to 2016 were included. Considered factors were defined as "type of unit", "type of abutment", "intraoral region", and "vitality". Modified UHPHS criteria were used for evaluation. Statistical analysis was performed using cox-regression. RESULTS. 189 units (94.0%) showed no kind of failure. 5 chippings (2.4%) could be corrected by intraoral polishing. 4 units (1.9%) exhibited spontaneous decementation. These polishable and recementable restorations are still in clinical use. Chippings or decementations, which lead to total failure, did not occur. One unit was completely fractured (0.5 %). Biological failures (caries, periodontitis or periimplantitis) did not occur. The statistical analysis of the factors did not reveal any significant differences. CONCLUSION. Modern all-ceramic FPDs seem to be an appropriate therapy not only for single restorations but for complex occlusal rehabilitations.

• 농촌의학ㆍ지역보건
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• 제35권1호
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• pp.46-55
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• 2010

Objectives: The aim of this study was to investigate the association of social support and quality of life of stroke patients. Methods: Stroke patients were interviewed by a direct contact survey among 160 person. A structured questionnaire was configured about demographic features, social support and health related quality of life(SF12). Data were collected from July to August 2009. Results: Among social support, satisfaction of dependable when you need help is the highest score(5.3) and console you when you are very upset is the lowest(4.0). Vitality among health related quality of life(HRQOL) is the higest score(55.9) and general health score is the the lowest(17.4). Physical component score(PCS) is lower than mental component. The results of multiple regression analysis about the factors affecting the PCS and MCS score, disability grade and feel better variable gave effect HRQOL. Conclusions: For improvement of HRQOL, among stroke patients, community social support, specially, when patients feeling generally down-in-the dumps, the rely on to help feel better was needed.

• 대한한방부인과학회지
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• 제25권2호
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• pp.154-173
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• 2012

Objectives: The aim of this study is to find out the effects of dance movement therapy(DMT) on anxiety, depression, and life quality by applying DMT program to climacteric women. Methods: The subjects of the research are climacteric women between the ages of 45 and 55 who located in the city of oo in Chollabukdo. The program was conducted with the subjects of a total of 27 women less than one year after menopause, 14 in the experiment group and 13 in the comparison group, 90 minutes a session, once a week, for 15 weeks. Results: The results show that the points of anxiety and depression decreased significantly in the experiment group which participated in the DMT program (p<0.05). The points of life increased significantly in physical & mental wellbeing, competence, and stability (p<0.05). Vitality points increased, but not significantly. Conclusions: This means that DMT decreases anxiety and depression of climacteric women, has positive effects on life quality related to health, and can help increase physical, mental, and emotional wellbeing of climacteric women.

• 한국환경복원기술학회지
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• 제15권5호
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• pp.165-176
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• 2012

The objective of this study is to set urban ecosystem assessment indicators, assess the status of the urban ecosystems in 31 cities & counties in the capital region and based on which, to examine an improvement plan to resolve problems and raise quality and quantity of urban ecosystems. The study showed that the ecological base of 31 cities & counties was 48% on average, which indicates that their ecological property is the middle class. Their natural-ecological function was 63% and environmental-control function was 25%, showing that environment-control function was poor. Therefore, going forward, urban ecological base should be further improved. When securing an ecological base, creation techniques should be able to further enhance environmental-control function along with natural-ecological function. Also, additional effort should be made to conserve areas with high ecological value as much as possible and increase vegetation vitality by replacing tree species.

• Journal of Information Technology Applications and Management
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• 제16권3호
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• pp.29-43
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• 2009

The advancement of emerging technologies can create more national value, and this motivates many nations to invest their resources in the emerging technologies. However, due to limited financial and human resources, even a wealthy nation cannot afford to randomly invest its resource in all profitable technologies. Therefore, cautious appraisal and prioritization of the competitive technologies should be conducted first, and then concentrated investment should be done for only the selected technologies. In this study, we propose a quantitative criterion for prioritizing the targeted electronic device technologies. The prioritization scheme devised in this study consists of a growth layer, a profitability layer, a vitality layer, and an influence layer. The proposed model forecasts the most promising technologies by applying the revised version of the Analytic Hierarchy Process (AHP). We performed empirical experiments on 12 emerging electronic device technologies to analyze the practical applicability of our study. The experimental data was obtained from 70 experts in high-tech industry as a part of the 2004 Prioritization and Selection project that was carried out in South Korea. As a result, the proposed scheme was able to present the most promising areas for investment in the field of electronic device technology.

• Restorative Dentistry and Endodontics
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• 제38권4호
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• pp.227-233
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• 2013

Objectives: The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement. Materials and Methods: A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were followed clinically for six months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulp inflammation, and calcified bridge formation. Results: All patients were free of clinical signs/symptoms of pulpal/periradicular diseases during the follow up period. In CH group, one tooth had necrotic radicular pulp; other two teeth in this group had vital uninflamed pulps with complete dentinal bridge formation. In CEM cement and MTA groups all teeth had vital uninflamed radicular pulps. A complete dentinal bridge was formed beneath CEM cement and MTA in all roots. Odontoblast-like cells were present beneath CEM cement and MTA in all samples. Conclusions: This study revealed that CEM cement and MTA were reliable endodontic biomaterials in full pulpotomy treatment. In contrast, the human dental pulp response to CH might be unpredictable.

• 디지털콘텐츠학회 논문지
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• 제16권5호
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• pp.767-773
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• 2015

본 연구는 신뢰성 기반의 상가건물 권리분석 프로그램을 개발하기 위한 연구로서 기존의 권리분석 프로그램에서 진일보하여 보다 현실에 부합한 분석방법을 제시하고 있다. 기존 연구는 단순히 직전 3개월에서 1년 사이의 경매낙찰가율과 경매낙찰가를 예상하고 이를 토대로 권리분석을 수행하였다. 그러나 본 연구에서는 상권분석시스템에서 제공하는 상권활성화 정도를 권리분석프로그램에 입력변수로 활용하여 경매에서의 낙찰가를 예측하고 이를 토대로 권리분석을 수행하도록 하였다.