• 한국산학기술학회논문지
• /
• 제14권11호
• /
• pp.5423-5433
• /
• 2013

본 연구는 교육행정직 공무원이 단위학교의 행정을 수행하면서 겪고 있는 일상적 스트레스, 직무스트레스, 직무만족도에 관한 요인을 분석함을 목적으로 한다. 이를 위해 2013년 3월 10일부터 3월 30일까지 충북 청주시 청원군 소재 교육행정직 공무원 122명을 대상으로 설문조사를 실시하였다. 자료 분석은 SPSS Win 18.0 프로그램을 사용하여 t-test, 빈도분석과 신뢰도분석 방법으로 실시하였고, 실증분석은 유의수준 5%에서 검증하였다. 분석 결과, 인구통계학적 특성에 따른 직무만족도에 있어서 직급에 따른 직무만족도 차이는 유의미하나 성별, 연령, 종교, 교육 정도, 결혼 상태, 학교 급, 학교 규모, 경력, 음주, 흡연, 종교에 따른 차이는 유의수준 5%에서 유의미하지 않은 것으로 분석되었다. 인구통계학적 특성에 따른 직무만족도 하위요인에 있어서는 인사관리, 인간관계, 업무능력 부문에서는 요인별 내용과 유의미하나 조직 분위기는 유의수준 5%에서 유의미하지 않은 것으로 분석되었다. 또한 인구통계학적 특성에 따른 직무 스트레스 하위요인에서 양적 역할고에 대한 스트레스는 연령과 학교 급, 직급, 경력, 흡연에 따른 차이가 유의미하였으며, 경력발달에서는 흡연에 따른 차이가 유의미하였고, 역할갈등 및 모호성에 대한 스트레스에서는 인구통계학적 특성에 따른 차이가 유의수준 5%에서 유의미하지 않은 것으로 분석되었다. 본 연구의 시사점으로는 교육행정공무원에 대한 사회 환경적 배려가 요구되며, 아울러 인사관리보다는 업무능력 개발과 인간관계, 조직의 분위기 순의 배려가 요구됨을 들 수 있다.

• 인간식물환경학회지
• /
• 제22권1호
• /
• pp.53-63
• /
• 2019

The purpose of this study was to investigate the preference of plant environmental images for flower plant consumption. This study came up with a total of four treatments including one image without plants and three images with flower plants (three roses, rose gift, rose garden). We conducted a survey on 104 men and women through the Google (online) survey and analyzed the data. The preference was higher with statistical significance for environmental images with plants than the image without plants. The preference for environmental images of roses was highest in the order of rose gift > rose garden > three roses. As a result of the cross-tabulation analysis, it was found that there was a significant difference in the preference for environmental images of roses according to general characteristics such as educational background and residence type. In terms of educational background, 2-year college graduates showed higher preference for the three environmental images of roses with statistical significance compared to high school graduates, university graduates and masters or higher. As a result of determining the difference in preference according to residential types, residents of multiplex houses showed higher preference for the "rose garden" environment image than residents of detached houses (p < .05). As a result of examining stress and depression in everyday life, 48.1% (the highest) of the respondents answered that they were "under daily stress" and 48.1% (the highest) of the respondents claimed not to be "under much depression". This study investigated the difference in preference according to demographic characteristics and existence of plants, preference in environmental images using roses, correlation with daily stress and depression, and utility of publicity using photographic images of plants.

• Safety and Health at Work
• /
• 제10권2호
• /
• pp.205-212
• /
• 2019

Background: Workforce health is one of the primary and most challenging issues, particularly in industrialized countries. This article aims at modeling the major factors affecting accidents in the workplace, including general health, work-family conflict, effort-reward imbalance, and internal and external locus of control. Methods: A cross-sectional study was conducted in Esfahan Steel Company in Iran. A total of 450 participants were divided into two groups-control and case-and the questionnaires were distributed among them. Data were collected through a 7-part questionnaire. Finally, the results were analyzed using SPSS 22.0 and Amos software. Results: All the studied variables had a significant relationship with the accident proneness. In the case group, general health with a coefficient of -0.37, worke-family conflict with 0.10, effort-reward imbalance with 0.10, internal locus of control with -0.07, and external locus of control with 0.40 had a direct effect on occupational stress. Occupational stress also had a positive direct effect on accident proneness with a coefficient of 0.47. In addition, fitness indices of control group showed general health (-0.35), worke-family conflict (0.36), effort-reward imbalance (0.13), internal locus of control (-0.15), and external locus of control (0.12) have a direct effect on occupational stress. Besides, occupational stress with a coefficient of 0.09 had a direct effect on accident proneness. Conclusion: It can be concluded that although previous studies and the present study showed the effect of stress on accident and accident proneness, some hidden and external factors such as work-family conflict, effort-reward imbalance, and external locus of control that affect stress should also be considered. It helps industries face less occupational stress and, consequently, less occurrence rates of accidents.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권10호
• /
• pp.5961-5964
• /
• 2013

Background: Breast cancer in Kazakhstan and its Kyzylorda oblast is the most prevalent cancer in women and features increasing trends of incidence. The aim of study was to reveal risk factors for breast cancer among women of Kyzylorda oblast of Kazakhstan. Materials and Methods: A hospital-based case-control study was conducted at Kyzylorda oblast Oncology Center, including 114 cases of breast cancer and 196 controls. Binary logistic regression analysis was performed. Results: Social and behavioral risk factors for breast cancer were evaluated, among which unfavorable living conditions, chronic stress, unilateral breastfeeding, breastfeeding less than 3 months and over 2 years, abortions, and hereditary predisposition were found to be related with increased breast cancer risk. Breastfeeding for 6-24 months was found to be protective. Conclusions: The findings may have significant impact on activity planning aimed towards breast cancer reduction among women in Kazakhstan.

• 한국학교ㆍ지역보건교육학회지
• /
• 제8권1호
• /
• pp.43-54
• /
• 2007

This study aimed at investigating the level of high school students' entrance exam stress and mental health first and also investigating if the entrance exam stress and mental health are related to gender, grade, character type, parenting style and economic status. This is expected to be used as a fundamental data for the development of health education program on high school students' stress and diagnosis of their mental health. To achieve those goals above, the questionnaire was used and the sample consisted of 600 students from general high schools in a large city, C and in a smaller city, A in Chungnam province through questionnaire and the conclusion, which was based on 582 proper questionnaires from the 600 questionnaires, through variable analysis, correlation analysis and multi-regression, is below. First, according to the information provided by respondents, the result showed the relationship between those background variables and the entrance exam stress and mental health level. As the students are more introverted and the parenting style is more authoritative, the entrance exam stress is higher and the mental health level is higher as the parenting style is more authoritative and the economic status is lower. In gender, the entrance exam stress level was high for male students in regard to parents pressure. For female students, it was due to the insufficient free time. In test performance, the good grade group showed high stress level when they don't have enough free time and the poor grade group showed high stress level when they have test tension and poor test performance. In character style, the introverted group showed high stress level in future uncertainty. In parenting style, the authoritative group showed significantly high level in all four sub-factors and there is no significant relationship with the stress level and economic statue. Female students reported higher mental health level than male students in somatization and depression. In academic achievement, the poor grade group showed high level in obsession, fear-anxiety and psychotism. In character style, the introverted group showed high level in sensitivity towards others and depression. And in parenting style, the authoritative group is higher in 9 sub-factors than the other two groups in the factor, economic status. The lower economic status group showed high mental health problem level in this order; in obsession, sensitivity towards others, depression, paranonia and psychotism. Second, the results revealed that there is a significant difference among the groups after comparing and analyzing the relationship between the mental health level according to the three groups, the first, second and third group divided by the degree of entrance exam stress. And the higher the entrance exam stress is, the higher the mental health problem level is. Verification showed that there was obvious difference among the groups. the entrance exam stress was positively correlated with the mental health level. The lack of free time, future uncertainty, test anxiety/poor test performance and parents pressure, these factors, in that order, were correlated with the mental health level. when the prediction variables which influenced on mental health are analyzed, test-anxiety/poor test performance was found to be related to mental health most. And after the factor, test-anxiety, future uncertainty and the lack of free time were listed(ranked), however results did not show any correlation with parents' pressure.

• Tuberculosis and Respiratory Diseases
• /
• 제68권6호
• /
• pp.334-344
• /
• 2010

Background: Based on the known immunoregulatory functions of moxifloxacin on phagocytes, the therapeutic effect of moxifloxacin on oleic acid (OA)-induced acute lung injury (ALI) was investigated. Methods: Moxifloxacin (10 mg/kg) was given to male Sprague-Dawley rats that had been given oleic acid (OA, $30{\mu}L$) intravenously. Five hours after OA injection, parameters demonstrating ALI were assessed to measure the effects of moxifloxacin on acute lung injury. Results: The pathological findings of OA-induced ALI's was diminished by moxifloxacin. Through ultrastructural and $CeCl_3$ EM histochemistry, moxifloxacin was confirmed to be effective in decreasing oxidative stress in the lung as well. Indices of ALI, such as lung weight/body weight ratio, protein content in bronchoalveolar lavage fluid, and lung myeloperoxidase were decreased by moxifloxacin. In diaminobenzidine immunohistochemistry, fluorescent immunohistochemistry, and Western blotting of the lung, moxifloxacin had decreased the enhanced expression of secretory phospholipase $A_2$ ($sPLA_2$) by OA. Conclusion: We concluded that moxifloxacin was effective in lessening acute inflammatory pulmonary edema caused by OA, by inhibiting the neutrophilic respiratory burst, which was initiated by the activation of $sPLA_2$.

• 한국전문물리치료학회지
• /
• 제31권2호
• /
• pp.159-166
• /
• 2024

Background: For instance, forward head posture (FHP), characterized by the forward movement of the head relative to the spine, places significant stress on the neck and upper back muscles, disrupting the biomechanical balance of the body. Objects: The objective of this study was to probe the biomechanical effects of FHP on musculoskeletal health through a relative analysis of 26 adults diagnosed with FHP and 26 healthy controls. Methods: In this study, we evaluated the biomechanical impacts of FHP. Participants adjusted their head positions and underwent muscle strength tests, including electromyography assessments and the Biering-Sørensen test for trunk muscle endurance. Data analysis was conducted using Kinovea (Kinovea) and IBM SPSS software ver. 26.0 (IBM Co.) to compare muscle activities between groups with normal and FHPs. Results: The study shows that individuals with FHP have significantly lower muscle activity, endurance, and spinal extension in the erector spinae compared to those without, highlighting the detrimental effects of FHP on these muscles. Conclusion: This study underscores the impact of FHP on erector spinae function and emphasizes the need for posture correction to enhance musculoskeletal health and guide future research on intervention strategies.

• Nutrition Research and Practice
• /
• 제18권5호
• /
• pp.602-616
• /
• 2024

BACKGROUND/OBJECTIVES: Inflammation and ferroptosis are implicated in various diseases and lipopolysaccharides (LPS) have been linked with these disorders. Recently, many edible insects, such as Gryllus bimaculatus, Protaetia brevitarsis larvae (PB) and Tenebrio molitor larvae, have been recommended as alternative foods because they contain lots of nutritional sources. In this study, we explored the potential of PB extract in preventing LPS-induced inflammation and ferroptosis in Hep3B cells. MATERIALS/METHODS: PB powder was extracted using 70% ethanol and applied to Hep3B cells. Co-treatment with LPS was conducted to induce ferroptosis and inflammation. The anti-inflammatory and anti-ferroptosis mechanisms of the PB extract were confirmed using Western blot, enzyme-linked immunosorbent assay, and real-time polymerase chain reaction analysis. RESULTS: PB extract effectively prevented LPS-induced cell death and restored LPS-induced inflammatory cytokine production, NF-κB signaling, endoplasmic reticulum (ER) stress and ferroptosis. Interestingly, PB extract reduced LPS-induced ceramide increase and acid sphingomyelinase (ASMase) expression. The use of the ASMase inhibitor, desipramine, also demonstrated a reduction in these pathways, highlighting the pivotal role of ASMase in inflammation and ferroptosis. Treatment with each inhibitor revealed that ferroptosis causes ER stress and that NF-κB and MAP kinase pathways are involved in inflammation. CONCLUSION: PB emerges as a potential functional food with inhibitory effects on LPS-induced inflammation and ferroptosis, making it a promising candidate for nutritional interventions.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제17권1호
• /
• pp.21-28
• /
• 2017

Background: The skin consists of tightly connected keratinocytes, and prevents extensive water loss while simultaneously protecting against the entry of microbial pathogens. Excessive cellular levels of reactive oxygen species can induce cell apoptosis and also damage skin integrity. Propofol (2,6-diisopropylphenol) has antioxidant properties. In this study, we investigated how propofol influences intracellular autophagy and apoptotic cell death induced by oxidative stress in human keratinocytes. Method: The following groups were used for experimentation: control, cells were incubated under normoxia (5% $CO_2$, 21% $O_2$, and 74% $N_2$) without propofol; hydrogen peroxide ($H_2O_2$), cells were exposed to $H_2O_2$ ($300{\mu}M$) for 2 h; propofol preconditioning (PPC)/$H_2O_2$, cells pretreated with propofol ($100{\mu}M$) for 2 h were exposed to $H_2O_2$; and 3-methyladenine $(3-MA)/PPC/H_2O_2$, cells pretreated with 3-MA (1 mM) for 1 h and propofol were exposed to $H_2O_2$. Cell viability, apoptosis, and migration capability were evaluated. Relation to autophagy was detected by western blot analysis. Results: Cell viability decreased significantly in the $H_2O_2$ group compared to that in the control group and was improved by propofol preconditioning. Propofol preconditioning effectively decreased $H_2O_2$-induced cell apoptosis and increased cell migration. However, pretreatment with 3-MA inhibited the protective effect of propofol on cell apoptosis. Autophagy was activated in the $PPC/H_2O_2$ group compared to that in the $H_2O_2$ group as demonstrated by western blot analysis and autophagosome staining. Conclusion: The results suggest that propofol preconditioning induces an endogenous cellular protective effect in human keratinocytes against oxidative stress through the activation of signaling pathways related to autophagy.

• Journal of Cancer Prevention
• /
• 제21권2호
• /
• pp.95-103
• /
• 2016

Background: Excess energy supply induces chronic low-grade inflammation in association with oxidative stress in various tissues including intestinal epithelium. The objective of this study was to investigate the effect of high-fat diet (HFD) on intestinal cell membrane integrity and intestinal tumorigenesis in $Apc^{Min/+}$ mice. Methods: Mice were fed with either normal diet (ND) or HFD for 12 weeks. The number of intestinal tumors were counted and biomarkers of endotoxemia, oxidative stress, and inflammation were determined. Changes in intestinal integrity was measured by fluorescein isothiocyanate (FITC)-dextran penetration and membrane gap junction protein expression. Results: HFD group had significantly higher number of tumors compared to ND group (P < 0.05). Blood total antioxidant capacity was lower in HFD group, while colonic 8-hydroxy-2'-deoxyguanosine level, a marker of oxidative damage, was higher in HFD group compared to that of ND group (P < 0.05). The penetration of FITC-dextran was substantially increased in HFD group (P < 0.05) while the expressions of membrane gap junction proteins including zonula occludens-1, claudin-1, and occludin were lower in HFD group (P < 0.05) compared to those in ND group. Serum concentration of lipopolysaccharide (LPS) receptor (CD14) and colonic toll-like receptor 4 (a LPS receptor) mRNA expression were significantly higher in HFD group than in ND group (P < 0.05), suggesting that significant endotoxemia may occur in HFD group due to the increased membrane permeability. Serum interleukin-6 concentration and myeloperoxidase activity were also higher in HFD group compared to those of ND group (P < 0.05). Conclusions: HFD increases oxidative stress disrupting intestinal gap junction proteins, thereby accelerating membrane permeability endotoxemia, inflammation, and intestinal tumorigenesis.