• Title/Summary/Keyword: Scaling up

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Effects of locally-delivered minocycline hcl on controlled periodontal disease (Minocycline 국소 약물 방출 제제의 치주질환 치료 효과)

  • Chung, Mi-Hyun;Kwon, Young-Hyuk;Herr, Yeek;Lee, Man-Sup;Park, Joon-Bong
    • Journal of Periodontal and Implant Science
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    • v.28 no.1
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    • pp.37-56
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    • 1998
  • The purpose of this study was to evaluate the clinical and microbiological outcomes following the use of 30% minocycline-loaded polycaprolacton film and 2% minocycline-loaded gel that was applied locally into pockets combined with scaling and root planing. 25 human subjects who were non-pregnant, non-lactating, aged 20-50 and diagnosed as moderate to advanced adult periodontitis were enrolled. Subjects were excluded if they had a history of severe acute or chronic systemic disease, if they required antibiotic prophylaxis for dental treatment for any reason, or if they reported a history suggestive of hypersensitivity reactions to minocycline or tetracycline. 4quadrants that had several teeth with a 5-8mm probing pocket depth and radiographic evidence of alveolar bone loss for each patient were selected and divided into test sites and control sites according to the split-mouth design. Scaling and root planing was done for each site at baseline(0week). Test sites received the minocycline gel and strip and control sites had saline irrigation. The patients received both treatments simyltaneously. Subgingival irrigation of sterile saline was applied to the control sites for approximately 30 seconds. Minocycline strip and gel was applied into the periodontal pocket at 1, 2, 3, 4 weeks each after scaling and root planing in the test sites. The clinical and microbiological measurements were made at baseline and at the follow-up visits 6, 10, 14, 20 weeks. The results of this study were as follows; 1. The sulcular bleeding index, probing pocket depth and Periocheck test was significantly reduced and the relative proportions of spirochetes and motile rods were significantly reduced and the proportion of cocci was correspondingly increased, in locally delivered minocycline strip group compared to saline irrigation group. 2. In locally delivered minocycline gel group, The effect was the same with minocycline strip group as compared with saline irrigation therapy. 3. There was no significant differences between minocycline strip group and minocycline gelgroup. In conclusion, minocycline HCl local drug delivery combined with scaling and root planing may provide added improvement of clinical and microbiological responses by inhibiting bacterial recolonization of treated sites. It is suggested that the local administration of minocycline-HCl in the periodontal pocket is effective when combined with subgingival mechanical debridement.

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Assessing Water Quality of Siheung Stream in Shihwa Industrial Complex Using Both Principal Component Analysis and Multi-Dimensional Scaling Analysis of Korean Water Quality Index and Microbial Community Data (Principal Component Analysis와 Multi-Dimensional Scaling 분석을 이용한 시화공단 시흥천의 수질지표 및 미생물 군집 분포 연구)

  • Seo, Kyeong-Jin;Kim, Ju-Mi;Kim, Min-Jung;Kim, Seong-Keun;Lee, Ji-Eun;Kim, In-Young;Zoh, Kyung-Duk;Ko, Gwang-Pyo
    • Journal of Environmental Health Sciences
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    • v.35 no.6
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    • pp.517-525
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    • 2009
  • The water quality of Lake Shihwa had been rapidly deteriorating since 1994 due to wastewater input from the watersheds, limited water circulation and the lack of a wastewater treatment policy. In 2000, the government decided to open the tidal embankment and make a comprehensive management plan to improve the water quality, especially inflowing stream water around Shihwa and Banwol industrial complex. However, the water quality and microbial community have not as yet been fully evaluated. The purpose of this study is to investigate the influent water quality around the industrial area based on chemical and biological analysis, and collected surface water sample from the Siheung Stream, up-stream to down-stream through the industrial complex, Samples were collected in July 2009. The results show that the downstream site near the industrial complex had higher concentrations of heavy metals (Cu, Mn, Fe, Mg, and Zn) and organic matter than upstream sites. A combination of DGGE (Denaturing Gradient Gel Electrophoresis) gels, lists of K-WQI (Korean Water Quality Index), cluster analysis, MDS (Multi-Dimensional Scaling) and PCA (Principal Component Analysis) has demonstrated clear clustering between Siheung stream 3 and 4 and with a high similarity and detected metal reducing bacteria (Shewanella spp.) and biodegrading bacteria (Acinetobacter spp.). These results suggest that use of both chemical and microbiological marker would be useful to fully evaluate the water quality.

Image scaling scheme using the intra mode information in H.264/AVC decoder (H.264/AVC 복호화기에서 복호된 인트라 모드 정보를 이용한 화면 해상도 변환 방법)

  • Chae, Jin-Ki;Han, Jong-Ki
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2013.06a
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    • pp.296-299
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    • 2013
  • 디스플레이 기술이 발전함에 따라 다양한 크기의 디스플레이를 탑재한 장치들이 등장하게 되었고, 다양한 디스플레이 크기만큼 다양한 해상도를 사용하고 있다. 때문에 비디오 코덱과 scaler는 보편적으로 함께 사용된다. 그러나 기존의 scaler는 비디오 코덱의 복호화기와 화면 해상도 변환 모듈이 독립적으로 구성되고, 서로 간에 정보를 이용하지 않으므로 시스템의 성능 개선에 한계가 존재하였다. 즉, 비디오 코덱의 복호화기는 비트스트림으로부터 복호한 정보를 바탕으로 영상을 복원하고, 복원영상은 up/down scaler에서 확대/축소를 수행한다. 하지만 비디오 코덱의 비트스트림에 존재하는 정보는 영상의 특성을 반영하기 때문에 up/down scaler에서 비디오 코덱의 복호화기에서 복호된 정보를 이용하면 복잡도의 증가 없이 효율적인 확대/축소를 수행할 수 있다. 이에 본 논문에서는 비디오 코덱 중 차세대 비디오 코덱인 H.264/AVC 복호화기에서 생성된 복원 영상에 대해서 별도로 영상의 특성을 계산하는 모듈 없이 H.264/AVC 복호화기에서 복원된 정보 중 인트라 모드 정보를 바탕으로 영상의 특성에 맞는 up/down scaler를 구현하는 방법을 제안한다. 이 방법은 기존의 scaler들보다 물체의 경계영역을 더 선명하게 확대하는 효과를 보인다.

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Hardware Implementation of an Advanced Image Scaler for Mobile Device Using the Group Delay (Group Delay를 이용한 모바일 기기용 고성능 해상도 확대기의 하드웨어 구현)

  • Kim, Joo-Hyun;Park, Jung-Hwan;Choi, Won-Tae;Kang, Bong-Soon
    • Journal of the Institute of Convergence Signal Processing
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    • v.8 no.3
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    • pp.163-170
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    • 2007
  • In this paper, we propose that the polyphase scaler whose performance to that of the bicubic method, has less complexity in hardware structure. In order to get the new information, proposed system is based on the group delay which is one of the digital filter characteristics. The performance of this system is superior to that of bicubic algorithm which is well known. Because the hardware structure is simpler than other image scalers, we can adopt this system for mobile devices easily. The previous polyphase filters make blurring noise which is generated by up-scaling. We replace polyphase filters by boost-up filter to get vivid image. The proposed scaler is verified by Xilinx Virtex2 FPGA and is used as digital Boom in mobile camera phone.

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Study of maintenance behavior based on the experience of the tooth brushing instruction for implant patient (임플란트 환자의 잇솔질 교육경험에 따른 유지관리행태 연구)

  • Jeon, Ji-Hyun;Min, Hee-Hong
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.3
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    • pp.403-410
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    • 2013
  • Objectives : This study aims to provide the basic data for the maintenance and management of healthy implants through finding out the educational experience of toothbrushing and the oral hygiene management for the implant patients and to determine the maintenance measure. Methods : From April 1 to october 1, 2012, 250 patients in the dental clinic in Daejeon completed the self-reported questionnaire. Results : As for the educational experience of toothbrushing, 66.4 percent received the training for toothbrushing and 33.6 percent had not received the training for toothbrushing. Those who brushed three times a day accounted for 74.1 percent. Those who received the training for toothbrushing comprised 56.0 percent and took regular check up of every 6 months. Approximately 50.0% received regular scaling service every 6 months. Periodical medical check up comprised 55.6% among those who received toothbrushing education. Approximately 63.9% thought that periodical medical check up is the most important to maintain oral health. Conclusions : There were important factors for oral health. They were tooth-brushing, the utilization of various oral hygienic products, and the awareness of importance of oral hygiene management. The customized education program for the general public should be implemented as regular as possible.

The Change of Geographical Names' Territory and Representation of Place Identity with Place Names : A Case Study of Chungju Geographical Names (지명을 통한 장소정체성 재현과 지명영역의 변화 : 충주지역 지명을 사례로)

  • Lee, Young-Hee
    • Journal of the Korean association of regional geographers
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    • v.16 no.2
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    • pp.110-122
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    • 2010
  • This article is to study the characteristics of Chungju geographical names using the concepts which are the place identity, the politics of scale, and the competition of place names' territory for the diverse study methods of geographical names. According to this results, the new name of 'Suanbo-Myun' revealed the place identity, because it has not only the property of 'Suanbo hot spring' but also the three conditions called 'the numerical solitary', 'the qualitative identity', and 'the self-identity' which are the conditions for the place identity. In relation to the politics of scale through place names, the example of scaling up is 'Yian-Myun' which is former name of 'Chungju city Yiru-Myun', and the cases of scaling down are 'the up and down of Chungju Up Ho', the reductional change from 'Chungju-Gun' to 'Chungju-Myun' and the change of Chinese name of the 'Wolak Mountain'. Lastly, the examples of place names' territory change are two types. One is 'Chungju Yongdu-Dong' and 'Yiru-Myune Geumgok-Ri' for the cases that the place name and its territory were changed. The other is 'Dalchon river' that the place name's territory was only changed. In conclusion, this study suggested that place names are useful in order to represent and construct the place identity.

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Effect of scaling and root planing on the expression of anti-inflammatory cytokines (IL-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid of electronic cigarette users and non-smokers with moderate chronic periodontitis

  • Al-Hamoudi, Nawwaf;Alsahhaf, Abdulaziz;Deeb, Modhi Al;Alrabiah, Mohammed;Vohra, Fahim;Abduljabbar, Tariq
    • Journal of Periodontal and Implant Science
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    • v.50 no.2
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    • pp.74-82
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    • 2020
  • Purpose: The aim of this cross-sectional study was to investigate the effect of scaling and root planing (SRP) on the expression of anti-inflammatory cytokines (interleukin [IL]-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid (GCF) of electronic cigarette users and non-smokers with moderate chronic periodontitis (CP). Methods: Electronic cigarette users and non-smokers with CP were included in the study. Full-mouth plaque and gingival indices, probing depth (PD), clinical attachment loss (CAL), and marginal bone loss (MBL) were assessed. The GCF was collected, and its volume and levels of IL-4, IL-9, IL-10, and IL-13 were assessed. These parameters were evaluated at baseline and 3 months after SRP. The sample size was estimated, and comparisons between groups were performed. P<0.05 was considered to indicate statistical significance. Results: Thirty-six electronic cigarette users (47.7±5.8 years old) and 35 non-smokers (46.5±3.4 years old) with CP were included. At baseline, there were no differences in plaque index (PI), PD, CAL, MBL, and GCF IL-4, IL-9, IL-10, and IL-13 between electronic cigarette users and nonsmokers. At the 3-month follow-up, there were no significant differences in PI, gingival index (GI), PD, CAL, and MBL in electronic cigarette users compared to baseline, while there were significant reductions in PI, GI, and PD among non-smokers. At the 3-month follow-up, GCF IL-4, IL-9, IL-10, and IL-13 levels were significantly elevated in both groups (P<0.05) compared to baseline. The increases in GCF IL-4, IL-9, IL-10, and IL-13 levels were significantly higher in non-smokers (P<0.05) than in electronic cigarette users at the 3-month follow-up. Conclusions: Levels of GCF IL-4, IL-9, IL-10, and IL-13 increased after SRP in electronic cigarette users and non-smokers with CP; however, the anti-inflammatory effect of SRP was more profound in non-smokers than in electronic cigarette users.

Scale-up Fabrication of Flat Sheet Membrane by Using a Roll-to-Roll Process (롤투롤 공정을 활용한 평판형 분리막의 대면적 제조 연구)

  • Dong Hyeok Baek;Youngmin Yoo;In-Chul Kim;You-In Park;Seung-Eun Nam;Young Hoon Cho
    • Membrane Journal
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    • v.34 no.1
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    • pp.79-86
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    • 2024
  • The flat sheet membrane, one of the representative forms of polymeric membranes, is widely used from material research in laboratories to commercial membrane production due to its ease of fabrication. Porous polymeric flat sheet membranes used in microfiltration and ultrafiltration are mainly fabricated through phase separation processes, utilizing non-solvent-induced and vapor-induced phase separation methods. However, due to the nature of phase separation processes, variations between samples can easily occur depending on the surrounding environment and the experimenter, making it difficult to ensure reproducibility. Therefore, for scaling up and ensuring reproducibility of developed membrane fabrication technologies, there is a need for a controlled environment continuous large-area production device, such as a roll-to-roll manufacturing system. This research compared the changes in membrane characteristics due to differences in manufacturing environments when scaling up laboratory-scale fabrication technologies to roll-to-roll processes using knife and slot die coaters. By optimizing the continuous manufacturing process factors, uniformity of the membrane was ensured during large-area production.

Clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients: a retrospective study

  • Han, Ji-Young;Park, Seo Hee;Kim, Joohyung;Hwang, Kyung-Gyun;Park, Chang-Joo
    • Journal of Periodontal and Implant Science
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    • v.51 no.3
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    • pp.163-178
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    • 2021
  • Purpose: The aim of this study was to evaluate clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients. Methods: In total, 52 patients with at least 2 years of follow-up after periodontal and orthodontic treatment were included in this study. After scaling and root planing, orthodontic treatment with fixed appliances or clear aligners was performed. Fixed retainers with twist-flex stainless steel wires were bonded to the palatal or lingual sides of anterior teeth. Changes in clinical parameters, including the plaque index, gingival index, calculus index (CI), probing pocket depth, and radiographic bone levels, were evaluated before bonding of fixed retainers and at a 12-month follow-up. Cumulative survival rates (CSRs) for retainer failure were evaluated according to sex, site, CI, stage of periodontitis, and the severity of the irregularity with the log-rank test and hazard ratios (HRs). Results: Twelve months after bonding of fixed retainers, improvements were observed in all clinical parameters except CI and radiographic bone gain. The overall CSR of the retainers with a CI <1 at the 12-month follow-up after bonding of fixed retainers was significantly higher than that of the retainers with a CI ≥1 at the 12-month follow-up (log-rank test; P<0.001). Patients with stage III (grade B or C) periodontitis had a higher multivariate HR for retainer failure (5.4; 95% confidence interval, 1.22-23.91; P=0.026) than patients with stage I (grade A or B) periodontitis. Conclusions: Although fixed retainers were bonded in periodontitis patients, periodontal health was well maintained if supportive periodontal treatment with repeated oral hygiene education was provided. Nonetheless, fixed retainer failure occurred more frequently in patients who had stage III (grade B or C) periodontitis or a CI ≥1 at 12-month follow-up after bonding of fixed retainers.

Toward Transparent Virtual Coupling for Haptic Interaction during Contact Tasks (컨택트 작업 시 햅틱 인터렉션의 투명성 향상을 위한 Virtual Coupling 기법의 설계)

  • Kim, Myungsin;Lee, Dongjun
    • The Journal of Korea Robotics Society
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    • v.8 no.3
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    • pp.186-196
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    • 2013
  • Since its introduction (e.g., [4, 6]), virtual coupling technique has been de facto way to connect a haptic device with a virtual proxy for haptic rendering and control. However, because of the single dependence on spring-damper feedback action, this virtual coupling suffers from the degraded transparency particularly during contact tasks when large device/proxy-forces are involved. In this paper, we propose a novel virtual coupling technique, which, by utilizing passive decomposition, reduces device-proxy position deviation even during the contact tasks while also scaling down (or up) the apparent inertia of the coordinated device-proxy. By doing so, we can significantly improve transparency between multiple degree of freedom (possibly nonlinear) haptic device and virtual proxy. In other to use passive decomposition, disturbance observer of [3] is adopted to estimate human force with some dead-zone modification to avoid "winding-up" force estimation in the presence of device torque saturation. Some preliminary experimental results are also given to illustrate efficacy of the proposed technique.