• The Korean Journal of Pain
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• v.18 no.1
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• pp.39-42
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• 2005

Background: Besides its general anesthetic effect, ketamine interacts with sodium channels in a local anesthetic-like fashion, including the sharing of binding sites with those commonly used by clinical local anesthetics. This study evaluated the dose related effects of ketamine during epidural anesthesia with 0.5% ropivacaine. Methods: Sixty ASA physical status I II patients, scheduled for minor elective surgery under epidural anesthesia using 0.5% ropivacaine, were randomly divided into three groups (n = 20 each). The patients initially received either 0.5% ropivacaine (group 1), ketamine (0.1 mg/kg) in addition to the epidural 0.5% ropivacaine (group 2) or ketamine (0.2 mg/kg) in addition to the epidural 0.5% ropivacaine (group 3). The regression of sensory block was assessed by transcutaneous electric stimulation (TES), equivalent to a surgical incision. Motor block was assessed using the Modified Bromage's scale. Episodes of bradycardia, hypotension and sedation were also recorded. Results: There were no significant differences among the three groups in the maximal levels of sensory block or the times taken for these levels to be reached. The mean times for the block to regress to two and four segments below the maximal level were significantly prolonged by epidural ketamine. Conclusions: Epidural ketamine prolongs the duration of ropivacaine epidural anesthesia. These results suggest that ketamine has local anesthetic-like actions.

• Journal of Pharmaceutical Investigation
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• v.29 no.3
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• pp.217-225
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• 1999

These studies were designed to determine the effect of hydroalcoholic gel system (lower alkanol concentration: 40-60%) compared to general hydrogel system (lower alkanol concentration: 10-35%) on transdermal delivery of piroxicam and its anti-inflammatory activity. Piroxicam was incorporated into a hydroalcoholic gel and a hydrogel containing polymers, solvents, and cosolvents. The pH of gel was about 6.3-7.3 and the solvent mixtures were composed of water and various concentrations of ethanol (35, 40, 50, and 60%). For the in vitro study, the skin permeation of piroxicam from the gel formulations was investigated using Franz modified diffusion cells fitted with hairless mouse skin. For the in vivo study, the anti-inflammatory activity of hydroalcoholic gel was compared to other commercial products (piroxicam hydrogel and ketoprofen hydrogel) in rat and human. The anti-inflammatory activity was determined using carrageenan induced foot edema model in rat. For the clinical study, it was evaluated from determining efficacy and acceptability with 98 patients suffering from musculoskeletal pain. A novel piroxicam hydroalcoholic gel was successfully formulated in the range of 40-50% of ethanol as solvent, more than 10% of propylene glycol, 5% of $Transcutol^{\circledR}$ and 1 % of benzyl alcohol. The skin permeation of piroxicam using hydroalcoholic gel system was greater than that of general hydrogel system $(flux\;:\;139.1-148.2\;{\mu}g/cm^2/hr\;vs.43.0-84.5 {\mu}g/cm^2/hr)$ in vitro. In carrageenan-induced edema model, the anti-inflammatory activity of hydroalcoholic gel was better than that of piroxicam hydrogel for edema inhibition (75.1 % vs. 62.9%, p

• Journal of the Korean association of regional geographers
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• v.15 no.6
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• pp.803-819
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• 2009

This study explores of the lowest social class segregation in the residential area of Yao city of the Osaka Prefecture. The Buraku people, who constitute a social class that was the object of societal discrimination and exclusion since the beginning of modem times, formed a segregated residential area of their own. During the process of an organized struggle against discrimination that was institutionally recognized, communal consciousness among the constituents was consolidated. Moreover, in the Yao city, Korean immigrants in Japan, another discriminated group, as well as Vietnamese refugees and Chinese, who are also social minorities, increased in number. Also, activities by the Buraku people and Korean immigrants in Japan to defend human rights and the rights of social minorities began to unfold. Recently, the number of small scale factories in the Buraku's Douwa District decreased due to relocation of manufacturing companies elsewhere throughout Japan and to the effects of depression. New non-Buraku houses began to appear one by one on the site where factories started to disappear. While the spatial separatism of Yao city, as part of the isolated Douwa District, is weakening, the struggle based on communal consciousness among the social minorities and continued human rights activity is exerting great influence upon the administrative policy of Yao city. In the case of Yao city, while the visual appearance of spatial segregation is weakening, the communal consciousness among the regional residents remains. From this perspective, it can be said that this case represents a modified form of isolated space or the social pattern of segregation which is in the stage of extinction.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.23 no.3
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• pp.258-264
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• 2011

A MCS technique is represented to stochastically analyze the uncertainties of wave forces exerted on the upright sections of composite breakwaters. A stochastical models for horizontal and uplift wave forces can be straightforwardly formulated as a function of the probabilistic characteristics of maximum wave height. Under the assumption of wave forces followed by extreme distribution, the behaviors of relative wave forces to Goda's wave forces are studied by the MCS technique. Double-truncated normal distribution is applied to take the effects of uncertainties of scale and shape parameters of extreme distribution into account properly. Averages and variances of relative wave forces are quantitatively calculated with respect to the exceedance probabilities of maximum design wave height. It is found that the averages of relative wave forces may be decreased consistently with the increases of the exceedance probabilities. In particular, the averages on uplift wave force are evaluated slightly larger than those on horizontal wave force, but the variations of coefficient of the former are adversely smaller than those of the latter. It means that the uncertainties of uplift wave forces are smaller than those of horizontal wave forces in the same condition of the exceedance probabilities. Therefore, the present results could be useful to the reliability based-design method that require the statistical properties about the uncertainties of wave forces.

• Journal of Korean Society of Environmental Engineers
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• v.29 no.5
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• pp.556-563
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• 2007

We carried out a laboratory scale experiment about the characteristics of chemically active species produced in hybrid gas-liquid discharges. The electrode configuration which had high voltage electrode in the gas phase and ground electrode in the liquid was utilized while high voltage electrode has been typically positioned in the liquid in other studies. Our electrode was configured in such a way as to increase the energy efficiency of chemical reactions by creating a higher electrical field strength and a narrower pulse width than the typical electrode configuration. The highest ozone concentration was obtained at 45 kV which was the medium value in operating voltages. The decrease of solution conductivity increased the resistance of liquid phase and the electric field strength through the gas phase, so ozone gene-ration rate was enhanced. The increase of voltage promoted the production rate of hydrogen peroxide by increasing the electric field strength. In a lower voltage, the increase of solution conductivity increased the degradation rate of $H_2O_2$, so the $H_2O_2$ generation rate decreased. On the other hand, the effects of UV radiation, shock waves etc. increased the $H_2O_2$ generation rate as the solution conductivity increased. A higher rate of $H_2O_2$ generation can be achieved by mixing argon to oxygen which generates a stronger and more stable discharges.

• Journal of the Korean Society of Hazard Mitigation
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• v.2 no.4 s.7
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• pp.131-141
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• 2002

Precast concrete (PC) panels are often used as retaining walls to support soil pressure. In such a case, the panels should be connected at the location where PC panels meet with a buttress. However, it is not easy to provide enough development length for the reinforcing steels due to the limited width of the buttress. If it happens, the width of buttress should be increased as large enough although it is not desirable. The critical section required for providing the development length is always located where the flexural moment is maximum. Thus it is the place the buttress width ends. Also it is the place that the reinforcing steels stressed to maximum. However, it is possible to make differentiate between the maximum moment location and the most stressed location of reinforcing steels. It means that the most stressed location of reinforcing steels, the critical section, can be moved to the other place where the moment is not maximum. New critical location will have less moment than that of buttress width ends. In consequence, the development length would be longer than that of the typical way of construction. Debonding or cutting technique make it possible to reduce the moment strength of a section. Therefore reinforcing steels are debonded or cut to have a desired flexural strength at a desired place. In this study, five test specimens in full scale were erected to examine the effects of critical section movement in PC panel joints. Test parameters were the length variations of debonded and cut reinforcing steels. The test results showed that the debonding or cutting technique could be used to lengthen the development length in the joint of PC panels.

• Journal of the Korean Society for Marine Environment & Energy
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• v.8 no.4
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• pp.186-192
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• 2005

We investigated the deposition characteristics and mass transport flux estimation of the Nakdong estuary, Korea. To understand the effects of the tidal current circulation that influences estuary terrain changes, we used a 2D numerical model to map seawater circulation under three different situations, with the level of river flow being set as none or flood. The net-water flux of the cross-sectional area between sandbars (known as dung) was estimated. From our review of previous research, we know that the development of local sandbars shifted from the west to the east side of the estuary after the construction of the Nakdong River dike. Current development is occurring mostly at the Bakhap-dung near Tadea. The seawater circulation pattern over this large-scale area of tidal na is brings changes related to the quantity of the outflow from the Nakdong River. Based on the calculated results for the net-water flux of the cross-sectional area, we see very strong accumulation in local waters around Jangjiado, Bakhapdung, and Tadae under flood river flow conditions, but accumulation in local waters around Jinudo under the other states of flow. Consequently, in the Nakdong estuary, the main sensitive regions that are affected by changes in the flow of river discharge are the local waters around Jangiado, Bakhapdung, Tadae, and Jinudo.

• Journal of the Korean Institute of Landscape Architecture
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• v.44 no.4
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• pp.66-74
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• 2016

In what way is the urban landscape of North Korea used today, and what features do people prefer in the North Korean landscape? This study analyzed the characteristics of Pyongyang landscapes and their effects, based on an analysis of Western tourists motivation for tourism in North Korea and preferred enjoyment-seeking experiences. Using data from the tourist agency specializing in Western tourism in North Korea and a location based photo-sharing service, the study interprets the visual distinctiveness of Pyongyang landscape. The study concluded that widely known risk to travelers in North Korea is in fact an attraction, making people want to visit directly. However, this risk was mitigated in practical experience by the overall intermediation of the tourism agency and locals' conscious behavior to keep their distance from foreigners. Next, the scope of National ritual attributes was expanded to the locals' daily life as well as large-scale events such as mass games and military parades only if for national holidays. Also, the most preferred factors contributing to North Korean tourism were based on departure from routine through mobilization of the residents. This indicates the extension that the nature of North Korea as a theater state. The Pyongyang landscape represents a world politically isolated, people's congregated motion to display to the world, and people's lives hidden beneath a veil. These visualities fulfill the fantasy of Westerners regarding North Korea. Furthermore, these are superficial images that help create a basis to maintain the North Korea regime.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4011-4020
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• 2015

The purpose of this study was to determine the self efficacy, body image and family support affect on postpartum depression in early postpartum mothers. The data was collected 306 mothers on the first week after delivery from one hospital located in B city. The instruments were a survey of general characteristics, obstetrical characteristics, the Edinburgh Postnatal Depression Scale(EPDS), self-efficacy, body image and family support. Data was analysed using descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression. The results revealed that the average item score of the EPDS was 6.09. The significant predictors of postpartum depression were body image, emotional state in pregnancy, and family support. These variables had a 38.4% explainability. The results indicate that the postpartum mothers should be screened for postpartum depression early in the postpartum period and it's necessary to implement nursing intervention focused on to enhance the body image and family support, especially the weak emotional state mothers in pregnancy.

• Journal of Korean Society of Rural Planning
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• v.26 no.4
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• pp.27-39
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• 2020

With the COVID-19 pandemic, the global economy has stagnated and our daily lives have changed. The rural economy is also experiencing damage, such as an average of 65% or more decrease in the number of visitors to rural experience resort villages due to the spread of COVID-19. In order to minimize the damage arising from the prolonged coronavirus, a hospitality system in response to changes in rural tourism behavior and consumer demand is needed to revitalize rural areas and maintain continuous economic independence. Therefore, this study attempted to find ways to utilize landscape resources such as education, culture, history, and ecology in order to complement the existing experience programs in connection with local resources and local environment. Wibong Village, which is the subject of the study, attempted to revitalize the village using the resources through the "Creative village creation" project in 2015. Due to poor management of historical resources, difficulty in operating experience programs, and response to changes in the natural environment, the rate of implementation of the project plan was very low. Currently, the demand for experience is also decreasing due to the COVID-19 effect, so it was judged that it was necessary to develop an experience village program suitable for the needs of experienced visitors by discovering additional local resources for the continuous operation of the experience village. In order to solve the problem of the use of landscape resources and the spatial composition of the study site, additional investigations of local resources were made, and an experience program course that could be operated by theme was proposed by configuring a space suitable for the use of landscape resources. By dividing the additionally investigated landscape resources into history, ecology, and region, an experiential course was created to separate the traffic lines, and the space composition for large-scale experienced visitors that had been previously operated was constructed in a form suitable for the post-corona era. In addition, at least two experiential tour courses that can be operated by period were proposed to maintain economic effects. Starting with this study, if further research on the creation and spatial composition of a rural experience village centered on the connection with the region, it will be used as research results that can be referenced in projects such as village creation, rural space planning, and living area analysis. It is expected that it will be able to effectively cope with the construction of a rural area suitable for the post-corona era, where demand is expected to increase in the future.