• 대한의용생체공학회:의공학회지
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• 제20권5호
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• pp.573-579
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• 1999

본 논문은 2채널 센서를 이용한 펄스 옥시메터의 산소포화도 계산 모델의 설계 및 분석에 관한 것이었다. 또한 Beer Lambert 법칙에 의거하여 기존 알고리즘 및 새로운 알고리즘들을 이론적으로 분석하였다. 제안된 알고리즘은 손가락을 투과한 2개의 채널에서 나온 광신호를 각각 직류성분 Adc 와 맥동성문 Aasin wt. 잡음성분 Ahnoise , ALnoise 등으로 모델링한다. 모델링 되어진 광신호를 맥동성분이 적분비를 사용하여 고주파 동잡음인 AHnoise 를 제거한 후 각각 산소포화도 계산을 위한 상관계수 그래프를 구한다. 또한 2개의 채널에서 적분비를 사용하여 구해진 상관계수 그래프를 사용하여 산소농도를 추출하는 방법에 관하여 기술하였다. 맥동성분비와 관혈적인 측정에 의한 혈중 산소포화도와의 상관관계 그래프의 선형성을 확보하기 위하여 펄스 옥시메터 시뮬레이터 오차범위를 고려해 75~100%상이의 산소포화도를 중점적으로 관측하였고, 4주기로 면적계산주기를 결정하여 실험하였다. 본 연구에서 제안된 알고리즘의 성능평가는 맥동성분의 적분비를 이용한 방법과 비교하였다. 비교결과는 4주기의 면적계산 주기를 가졌을 때 기존의 방식보다 평균오차가 0.7%정도 향상되었으며, 회귀적선의 신뢰도를 보여주는 결정계수 ${\gamma}$$^2$도 0.995로 기존의 방식에서 나온 0.979보다 더 좋은 결과를 얻을 수 있었다. 따라서 2채널을 이용한 방법이 A Lnoise 제거와 성능면에서 우수하다는 결론을 얻을 수 있었다.

• Journal of Electrical Engineering and Technology
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• 제9권5호
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• pp.1780-1787
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• 2014

Arterial oxygen saturation ($SpO_2$) monitoring for newborns requires special attention in neonatal intensive care units (NICUs). Newborns have very low photo-plethysmogram (PPG) amplitudes and their body movements are difficult to contain. Hardware design and its associated signal processing algorithms should be robust enough so that faulty measurements can be avoided. In this study, improved designs were implemented to deal with low perfusion, motion artifact, and the influence of ambient light. Dynamic range was increased by using different LED intensities and a feedback system. To minimize the effects of motion artifact and to discard other unqualified data, four additional algorithms were used, which were based on dual-trace detection, continuity of DC level, morphology of PPG, and simultaneity check of $SpO_2$. Our $SpO_2$ system was tested with newborns with normal respiration in the NICU. Our system provided fast, real-time responses and 100% artifact detection was accomplished under 84% of $SpO_2$.

• Tuberculosis and Respiratory Diseases
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• 제70권6호
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• pp.498-503
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• 2011

Background: The causes of exertional desaturation in patients with COPD can be multifactorial. We aimed to investigate factors predict exertional desaturation in patients with moderate to severe COPD. Methods: We tested 51 consecutive patients with stable COPD (FEV1/FVC, $40{\pm}13%$ predicted). Patients performed a six minute walk test (6MWT). Pulse oxymetric saturation (SpO2) and pulse rate were recorded. Results: Oxygen desaturation was found in 15 subjects after 6MWT, while 36 subjects were not desaturated. Lung diffusing capacity was significantly lower in desaturation (DS) group ($62{\pm}18%$ predicted) compared with not desaturated (ND) group ($84{\pm}20$, p<0.01). However there was no statistical difference of FEV1/FVC ratio or residual volume between two groups. The pulse rate change was significantly higher in the desaturated compared with the not desaturated group. Six minute walking distance, subjective dyspnea scale, airflow obstruction, and residual volume did not predict exertional oxygen desaturation. Independent factors assessed by multiple logistic regression revealed that a pulse rate increment (odd ratio [OR], 1.19; 95% confidence interval [CI], 1.01~1.40; p=0.02), a decrease in baseline PaO2 (OR, 1.105; 95% CI, 1.003~1.218; p=0.04) and a decrease in lung diffusing capacity (OR, 1.10; 95% CI, 1.01~1.19; p=0.01) were significantly associated with oxygen desaturation. Receiver operator characteristic (ROC) analysis showed that an absolute increment in pulse rate of 16/min gave optimal discrimination between desaturated and not desaturated patients after 6MWT. Conclusion: Pulse rate increment and diffusion capacity can predict exertional oxygen desaturation in stable COPD patients with moderate to severe airflow obstruction.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 춘계종합학술대회 A
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• pp.495-498
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• 2008

본 논문은 유비쿼터스 헬스케어 시스템을 위한 웨어러블 센서의 한 종류로서, 손목 착용형 $SpO_2$ 모듈을 구현하였으며 사용자의 산소포화도를 모니터링 할 수 있도록 제안하였다. $SpO_2$ 계측 보드는 고성능, 저전력 특징을 가지고 있는 MCU (ATmega128L, Atmel Co., USA)를 활용하여 모든 측정된 신호의 처리 및 제어를 담당하도록 하였으며, 일차적인 신호의 증폭과 필터를 위한 아날로그 회로도 구성하였다. 또한, 특정부위에서의 측정을 위해 제작된 반사형 프로브와도 연결되어 측정된 신호의 수집 및 처리를 담당하도록 하였다. IEEE 802.15.4 표준 프로토콜과 연동이 가능한 무선 센서 노드는 $SpO_2$ 계측 보드와 함께 연결되어 수집된 데이터를 서버측 PC로 전송하는 역할을 담당한다. 제안된 시스템의 활용으로 관리자가 서버측에서 모니터링 프로그램을 통해 사용자의 건강상태에 대한 정보를 확보할 수 있도록 하였다.

• 한국자기공명학회논문지
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• 제17권2호
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• pp.98-104
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• 2013

The ERETIC (Electronic REference To access In vivo Concentrations)2 method is a new qNMR experimental technique to measure analytes based on the signal of the reference compound without additional hardware equipment. In this study, ERETIC2 method was validated, and we sought to identify whether it would be possible to apply this method to a specific compound analysis of metabolites in plant. The $90^{\circ}$ pulse value (P1) and spin-lattice relaxation time ($T_1$) of each compound were measured for ERETIC2. The $9^1H$ of 3-(trimethylsilyl) propionic-2,2,3,3-$d_4$ acid (TSP) was used as a reference peak for ERETIC 2, and then, a suitable solvent and pulse sequence for each compound were selected. Under the NOESY-presat sequence, the relative accuracy error for quantitative analyses of primary metabolites was within the range of 5%, with the exception of glucose, which showed ${\geq}$ 55% error due to saturation. It showed excellent results for the quantification of glucose by using a $30^{\circ}$ pulse sequence, which did not suppress the water peak. In addition, the quantitative accuracy for secondary metabolites was extremely accurate, with an error ${\leq}$5% when considering the purity of the standard sample. The ERETIC2 method showed outstanding linearity, precision, and accuracy.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권6호
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• pp.397-402
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• 2020

Background: Inferior alveolar nerve block (IANB) is the most common, painful, and anxiety-provoking procedure involving needle insertion for anesthetic solution deposition. DentalVibeⓇ (DV) delivers vibration at a sustained frequency as a counter-stimulation to the site of injection, thereby alleviating pain. The aim of this study was to evaluate and compare the effectiveness of DV and lignocaine hydrochloride 2% gel (Lox 2% jelly) in pain reduction during IANB in children. Methods: A split-mouth randomized clinical trial was designed with a sample of 60 children (age, 6 to 12 years) requiring bilateral IANB for various dental procedures; DV was used while administering IANB and Lox 2% jelly was used as the topical anesthetic before administering IANB at subsequent appointments. During both appointments, pain perception was measured using the sound, eye, motor (SEM) scale and Wong-Baker faces pain rating scale (WBFPRS); oxygen saturation (SpO2) and pulse rate were measured using a pulse oximeter before, during, and after the IANB procedure. The obtained values were tabulated and subjected to statistical analysis. Wilcoxon test was used for intergroup comparison, and Friedman test, for intragroup comparison of measured variables at different treatment phases. Results: The medians and interquartile ranges of the WBFPRS scores recorded during the IANB procedure for DV and Lox 2% jelly were 2 (2-4) and 2 (0-2), respectively (P < 0.05). The SEM scale scores, mean SpO2, and pulse rate did not show any significant differences during the IANB procedure between both treatments. Conclusion: Both DV and Lox 2% jelly were found to be effective in pain reduction during IANB in children.

• 한국표면공학회지
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• 제35권3호
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• pp.127-132
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• 2002

High speed performance of ferroelectric Pb(Zr,Ti)$O_3$ (PZT) based capacitors is reported. La substitution up to 10% was performed to systematically lower the coercive and saturation voltages of epitaxial ferroelectric capacitors grown on Si using a ($Ti_{0.9}$ /$Al_{0.1}$ )N/Pt conducting barrier composite. Ferroelectric capacitors substituted with 10% La show significantly lower coercive voltage compared to capacitors with 0% and 3% La. This is attributed to a systematic decrease in the tetragonality (i.e., c/a ratio) of the ferroelectric phase. Furthermore, the samples doped with 10% La showed dramatically better retention and pulse width dependent polarization compared to the capacitors with 0% and 3% La. These capacitors show promise as storage elements in low power high density memory architectures.

• Journal of Korean Neurosurgical Society
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• 제45권4호
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• pp.249-252
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• 2009

We report on a case of thrombosis of the left common iliac artery following anterior lumbar interbody fusion (ALIF) of L4-5 in a 79-year-old man with no previous medical problems, including peripheral vascular disease. After completing the ALIF procedure, the surgeon could not feel the pulsation of the left dorsalis pedis artery, and the oxygen saturation ($SaO_2$) had fallen below 90% from pulse oxymetry on the left great toe. Thrombectomy was successfully performed after confirming the thrombus in the left common iliac artery using Computed Tomography (CT) angiography. Thrombosis of the common iliac artery is very rare following ALIF. However, delayed diagnosis can lead to disastrous outcome. Although elderly patients have no cardio-vascular disease or vessel calcification in pre-op evaluation, the possibility of a complication involving L4-5 should be considered.

• 한국정보통신학회논문지
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• 제16권6호
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• pp.1153-1157
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• 2012

안드로이드 기반의 스마트폰 기술의 발달에 따라 우리 생활에 다양한 변화를 가져오고 있다. 본 논문에서는 스마트폰을 기반으로 인간의 생체 정보인 맥파 및 산소포화도를 계측할 수 있는 단말기를 이용하여 환자의 상태를 모니터링 할 수 있도록 불루투스 기반의 u-헬스 케어시스템을 구현하였다. 본 논문의 구현을 통하여 불루투스를 지원하지 않고 PC에서만 모니터링 하는 의료 장비를 불루투스 모듈을 추가하여 스마트폰으로 데이터를 모니터링 할 수 있음을 확인하였다.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제54권10호
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• pp.470-476
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• 2005

In this paper PU control scheme is presented. The proposed scheme has following features. The one is oft-starting method which is used for preventing to flow large current in motor phase winding when motor starts. The ther is the selection of the level of the over current. The first feature is implemented by increasing the PWM duty lowly, the second feature is implemented by limiting the magnitude of the phase current level by which the over heat f motor by copper losses and magnetic saturation decreases. By the analysis using FEM considering load condition, the peed of mode transition from PW to single pulse control is selected and confirmed by simulation that there is no ver current occurs during the mode transition. For the verification of proposed scheme, the simulation using MATLAB Simulink with considering non-linearity of inductance profile from FEM analysis is performed and the experiment with SRM drive system which has the DSP controller and single Phase SRM are peformed.