• Journal of Sasang Constitutional Medicine
• /
• v.26 no.1
• /
• pp.98-109
• /
• 2014

Objectives This paper was aimed to review experimantal and clinical articles on Yeoldahanso-tang(YDHS), figuring out the recent tendency and suggesting the future prospects of YDHS-related studies. Methods The articles published in Korean or English since 2000 were searched, screened, and classified into experimental or clinical studies. And we structured designs, methods and results of the included studies into each table for the experimental studies or the clinical studies. Especially tools to diagnose constitutions and patterns identified in clinical researches were also summarized in the tables. Results 28 articles are finally included. 14 experimental studies are mostly in vitro designs to show efficacy of YDHS. There are only 2 studies for the safety. Among 14 clinical studies, 12 case studies target disorders of central nervous system, viral infection, skin ulcer and so on. 2 studies are before and after studies on cerebral infarction and effects on liver function. Conclusions Based on the efficacy of YDHS on central nervous system, it acquires higher level of evidence such as randomized controlled trials in the future. In addition other diseases such as skin ulcer and so on, it needs to be done more specific experimental or clinical studies so that we can get statistically significant results.

• Journal of Sasang Constitutional Medicine
• /
• v.23 no.1
• /
• pp.79-86
• /
• 2011

1. Objectives: Pharmacopuncture according to Sasang Constitutional Medicine is new field of constitutional medicine. We investigated safety of pharmacopunctures to develop this treatment. 2. Methods: We searched for papers in fifteen Korean oriental medical journals and four online searching portal articles. Hepatotoxicity, nephrotoxicity and general toxicity tests were investigated about one hundred thirty kinds of pharmacopunctures. 3. Results: Toxicity test about 36 kinds of 130 pharmacopunctures were investigated. 1) Hepatotoxicity and nephrotoxicity test of pharmacopunctures were searched in 11 of 38 Soeumin herbs, 8 of 36 Soyangin herbs, 5 of 44 Taeeumin herbs and 1 of 12 Taeyangin herbs. From among these herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Fructus alpiniae oxyphyllae(益智仁), Semen crotonis(巴豆), Radix bupleuri(柴胡) and Semen armeniacae amarum(杏仁) pharmacopunctures. 2) General toxicity test of pharmacopunctures were searched in 8 of 38 Soeumin herbs, 9 of 36 Soyangin herbs, 6 of 44 Taeeumin herbs and 2 of 12 Taeyangin herbs. from among thes herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Radix ginseng(人蔘), Semen crotonis(巴豆), Rhizoma seu radix notopterygii(羌活), Radix aralia cordatae(獨活), Semen armeniacae amarum(杏仁) and Radix scutellariae(黃芩) and Cortex acanthopanacis(五加皮) pharmacopunctures. 4. Conclusions: From these results, we must decide extraction method, concentration and dose carefully to use the toxic pharmacopuncture. More toxicity test and further study is needed about pharmacopuncture treatment in Sasang Constitutional Medicine.

• Journal of Sasang Constitutional Medicine
• /
• v.27 no.4
• /
• pp.429-435
• /
• 2015

Objectives The purpose of this study was to report the effects of treatments to traumatic subcutaneous hematoma on the shin using herbal medication and external application without venesection, which had no change in spite of previous 3 weeks medical conservative treatment so it had a risk of sepsis.Methods The patient diagnosed as Soyangin was prescribed with Yangkyuksanhwa-tang. The subcutaneous hematoma lesion was treated by external application of Daehwangchija-san(大黃梔子散). We evaluated the size of hematoma, pain and gait disturbance.Results and Conclusions Subcutaneous hematoma and relevant symptoms disappeared within 11 days of admission. Any kind of sequela did not show up and skin color was recovered after 4 month later follow-up.

• Journal of Korean Traditional Oncology
• /
• v.27 no.1
• /
• pp.49-56
• /
• 2022

Objective: This case report represented that Korean traditional medicine therapies can make effective results for chemotherapy-induced peripheral neuropathy(CIPN) patients. Methods: A 63-year-old female patient has been diagnosed with ovarian cancer(Sertoli-Leydig cell tumor). Total excision of uterus and appendages was operated, and Bleomycin, etoposide and cisplatin combination therapy was applied. After three cycles of chemotherapy, the severe side effects of neutropenia and CIPN occurred. Chemotherapy was terminated, but numbness and tingling pains in the limbs persisted for several months. We provided Korean medicine treatments including herbal medicine, pharmacopuncture, acupuncture, moxibustion and physiotherapies. Results: After treatments, the numbness and pain were reduced from 10 to 1 in hand and 6 to 0 on the numeric rating scale(NRS). Functional assessment of cancer therapy/Gynecologic oncology group neurotoxicity (FACT/GOG-NTX) score was improved from 58 to 97. Conclusion: According to these results, Korean medicine treatments could be considered effective for CIPN. Prospective studies are needed to confirm and expand these findings.

• Journal of Sasang Constitutional Medicine
• /
• v.23 no.4
• /
• pp.526-532
• /
• 2011

1. Objectives This study was designed to investigate the effect of Yanggyuksanhwa-tang(凉膈散火湯) to twelve hyperhidrosis patients. 2. Methods From May, 2008 to August, 2010, we treated hyperhidrosis patients with Yanggyuksanhwa-tang(凉膈散火湯). We survey demographic characters, symptoms of patients and efficacy of Yanggyuksanhwa-tang(凉膈散火湯). 3. Results 1) Twenties, thirties and males were more suffer from hyperhidrosis. 2) The patients who had dysuria got treatment efficacy negatively. 3) Treatment efficacy was affected by number of herbal medicine positively. 4. Conclusions This study shows that Yanggyuksanhwa-tang(凉膈散火湯) has effect to hyperhidrosis in Soeyangin. Treatment efficacy was affected by number of herbal medicine significantly.

• Journal of Sasang Constitutional Medicine
• /
• v.28 no.3
• /
• pp.215-224
• /
• 2016

Objectives This study aimed at proposing a hypothetical principle to add or abstract herbs for modifying Taeeumjowi-tang.Method Based on Jema Lee's literatures such as Dongyisusebowon and Dongyisasangsipyeon, we analyzed contents related to Taeeumjowi-tang and its modification. Moreover, we reviewed physiological and pathological pecularities of Taeeumin symptomatology and applied the theory to induce the principle of the modified Taeeumjowi-tang in Sasang medicine.Results and Conclusions 1) We have found 10 modified Taeeumjowi-tang from Dongyisasangsipyeon. 2) Mahwangjowi-tang (麻黃調胃湯), Gogijowi-tang (固氣調胃湯), Shingijowi-tang (腎氣調胃湯), Euiyiinjowi-tang (薏苡仁調胃湯), Gamijowi-tang (加味調胃湯), and Gyeongheomjowi-tang (經驗調胃湯) are modified for Taeeumin who have original symptoms of more severe cold tendency. Especially, Gogijowi-tang helps to circulate energy-fluid from esophagus to skin, while Shingijowi-tang directly aids the function of esophagus. 3) Seungjijowi-tang (升芷調胃湯), Seunggeumjowi-tang (升芩調胃湯), Seunggijowi-tang (承氣調胃湯), and Jowisokmyung-tang (調胃續命湯) are modified for Taeeumin who have originally cold symtoms, accompanied by heat tendencies. Especially, Seungjijowi-tang helps to eliminate mild heat existing throughout skin and flesh, while Seunggeumjowi-tang gets rid of severe heat swarming in the flesh parts. Seunggijowi-tang can take away the most severe heat symptoms in the whole body

• Journal of Sasang Constitutional Medicine
• /
• v.33 no.4
• /
• pp.57-64
• /
• 2021

Objectives This study was aimed to report significant improvement of gastroesophageal reflux disease (GERD) treated by Cheongsimyeonja-tang and acupuncture treatment in Taeeumin. Methods Patient who has GERD was treated with herbal medicine and acupunture from June 15 to July 6. Gastrointestinal Symptom Rating Scale (GSRS) was used to observe changes of digestive symptoms. Results After treatment, the GSRS of the patient improved from 4.8 to 2.6. Also, the patient's symptoms of sore throat, cough, phlegm and bowel sound were reported to be improved after treatment. Conclusions This study shows that Cheongsimyeonja-tang might be effective in Taeeumin type patient's GERD.

• Journal of Sasang Constitutional Medicine
• /
• v.14 no.3
• /
• pp.132-145
• /
• 2002

The purpose of this study is to examine the toxic effects caused by xanthine oxidase/hypoxanthine(XO/HX) and the effects of herbal extracts such as Cheongsimyeonjatang(CYT) on the treatment of the toxic effects. For this purpose, experiments with the cultured hippocampal cells from new born mice were done. The results of these experiments were as follows. 1. XO/HX, a oxygen radical-generating system, decreased the survival rates of the cultured cells on MTT assay and NR assay, protein synthesis, and amounts of neurofilaments. 2. CYT have the efficacy of increasing protein synthesis decreased by XO/HX. 3. CYT have the efficacy. of increasing the amount of neurofilaments decreased by XO/HX. From the above results, it is suggested that Cheongsimyeonjatang (CYT) have marked efficacy as a protection for the damages caused by the XO/HX-mediated oxidative stress.

• Journal of Sasang Constitutional Medicine
• /
• v.22 no.2
• /
• pp.28-36
• /
• 2010

1. Objectives: This paper was written to understand the origin, changes and the constructive principles of Jeokbaekhaogwanjung-tang(Chibaihewu-tang; 赤白何烏寬中湯). 2. Methods: Jeokbaekhaogwanjung-tang and other related prescriptions were analyzed in terms of pathology, based on "Donguibogam(東醫寶鑑)", "Donguisusebowon Chobongwon(東醫壽世保元 草本卷)", "Donguisusebowon Gabobon(東醫壽世保元 甲午本)", "Donguisusebowon Sinchukbon(東醫壽世保元 辛丑本)" and "Donguisasangsinpyeon(東醫四象新編)" 3. Results: and Conclusions: 1) The origin of Jeokbaekhaogwanjung-tang, which inherited the spirit of Zhang, Zhongjing(張仲景)'s Sasim-tang(Xiexin-tang; 瀉心湯), is discovered in the prescriptions for Sun-qi(順氣), that is, Gwanjung-hwan(Kuanzhong-wan; 貫衆丸) and Mokhyangsungi-san(Muxiangshunqi-san; 木香順氣散). 2) The Jeokbaekhaogwanjung-tang was derived from Gangchulpajeok-tang(Jiangzhupoji-tang; 薑朮破積湯) of "Dongyisusebowon Gabobon", where the herbal medicines, Panax ginseng(人蔘) of Sasim-tang was replaced with Cynanchum wilfordii(白何首烏) and Allium sativum(獨頭蒜) was newly used too. Thereafter, Polygonum multiflorum(赤何首烏) and Alpinia oxyphylla(益智仁) were first added in Jeokbaekhaogwanjung-tang in "Sinchukbon". 3) The Jeokbaekhaogwanjung-tang, composed of 8 herbs except for Zizyphus jujuba(大棗), treats Taeumjeung(太陰證) of Soeumin(少陰人) through warming the Stomach(溫胃) of Cynanchum wilfordii, Polygonum multiflorum, Zingiber officinale(乾薑) and Alpinia officinarum(良薑) and downbearing the Yin(降陰) of Citrus reticulata(靑皮), Citrus unshiu(陳皮), Cyperus rotundus(香附子) and Alpinia oxyphylla.

• Journal of Sasang Constitutional Medicine
• /
• v.27 no.1
• /
• pp.171-177
• /
• 2015

Objectives The purpose of this study is to give an account of the effects of the Traditional Korean herbal medicine therapy which is based on the Sasang constitutional medicine on psoriasis Methods We diagnosed her as Soyangin(少陽人) based on her nature and emotion, physical chracteristics, symptoms. We thought Leaky Gut Syndrome is related to Soyangin Food Stagnation, stuffiness and fullness(食滯痞滿). So we applied Dokhwaljihwang-tang(獨活地黃湯) which is used to Soyangin Food Stagnation, stuffiness and fullness because her symptoms recurred as a result of Food Stagnation(食滯) after eating meat. The improvement of the skin condition was observed by Psoriasis Area and Severity Index (PASI) score Results Psoriasis patient who was treated with Soyangin Dokhwaljihwang-tang showed improvement in Psoriasis symptom. This case study describes the effectivenss on psoriasis symptoms by using Soyangin Dokhwaljihwang-tang. Conclusions The PASI score of the patient reduced from 10.8 to 1.2 after three months of treatment. According to the result, we concluded that Dokhwaljihwang-tang had a good effect on psoriasis.