• 한국치위생학회지
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• 제17권4호
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• pp.693-704
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• 2017

Objectives: The purpose of study is to investigate trends in dental hygiene research published in the Journal of Korean Society Dental Hygiene. Methods:Total of 992 researches were published between 2001 to 2015 were reviewed using analysis criteria. Results: 23.7% of the researches were supported financially. The most frequent research topics were oral health (40.9%). 3 to 5 researchers per research (38.5%) was most common and 84.1% of principal researchers were professors. 29 researchers were approved by IRB (2011 to 2015). As for the type of research, 87.1% of quantitative studies adapted survey and 9.5% adapted experiment. Convenient sampling was used in 85.6% of the researches. 32.7% of studies searched information in school. Interventions of dental material were the most in pre experimental design (19.2%) and Interventions of activation of oral health program were the most in quasi experimental design (37.5%). Conclusions: The findings of this study suggested the recent trends and the direction in dental hygiene research.

• 한국축산식품학회지
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• 제31권1호
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• pp.40-46
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• 2011

The growth profile of Bacillus cereus in ready-to-eat (RTE) food products of animal origin was examined under different temperature and incubation conditions. In sandwiches and Kimbab, B. cereus did not grow or exhibited only minimal growth at 4 and $10^{\circ}C$, but it grew rapidly at ambient temperature. In sandwiches, B. cereus did not grow efficiently at $25^{\circ}C$, however, in ham, the main ingredient of sandwiches, B. cereus growth was observed at the same temperature, with bacterial levels reaching 7.94 Log CFU/g after incubation for 24 h at $25^{\circ}C$. Toxigenicity of B. cereus was observed only at temperatures above $25^{\circ}C$. In Kimbab, B. cereus produced toxin after 9 h at $30^{\circ}C$ and after 12 h at $25^{\circ}C$. Ingredients of sandwiches and Kimbab were collected from 3 different Korean food-processing companies to investigate the source of contamination by B. cereus. Among the 13 tested food items, 6 items including ham were found to be contaminated with B. cereus. Of these ingredients, B. cereus isolates from 3 items produced enterotoxins. None of these isolates harbored the emetic toxin-producing gene. The findings of the present study can be used for risk assessments of food products, including ham and cheese, contaminated with B. cereus.

• 대한한방내과학회지
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• 제28권3호
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• pp.586-596
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• 2007

Objectives : This study aimed to investigate the underlying protective mechanism of Rhizoma Arisaematis(RA) on 3-NP-induced Cytotoxicity in rat C6 glial cells. Methods : We investigated treatment ofC6 cells with 20mM 3-NP and pretreatment with RA to cause loss of cell viability. and morphological change. which was associated with elevation of ROS level. increase in Bax/Bcl2 ratio and HIF-a protein expression Results : RA inhibited 3-NP-induced cell death in C6 glial cells and inhibited the changes of the : MMPT (mitochondria membrane potential transition) and inhibited the decrease of mitochondria complex II activity and 3-NP-induced ROS generation in C6 cells. And RA decreased the activity of HIF-a and Bax. and increased the activity of $Bcl_2$ in C6 glial cells Conclusions : RA markedly protects C6 glial cells from 3-NP-induced oxidative injury.

• 한국축산식품학회지
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• 제36권1호
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• pp.23-28
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• 2016

This study investigates the effect of cooking, storage, and reheating conditions on the formation of cholesterol oxidation products (COPs) in pork loin. Samples of pork loin procured 24 h postmortem were initially processed and assessed for total fat and cholesterol content. The cooking methods evaluated were pan roasting, steaming, oven grilling, and microwaving. Cooked pork loin samples were stored at 4℃ and reheated after 3 and 6 d of storage using the original method of preparation or alternately, microwaving. Fat content increased significantly with cooking as a result of the loss in moisture but cholesterol content remained unchanged. Pan roasting and microwave cooking caused a significantly higher production of COPs, as with the process of reheating using microwave, pan roasting, and oven grilling methods. The major COPs found in pork loin were cholestanetriol, 20-hydroxycholesterol, and 25-hydroxycholesterol, whose concentrations varied according to the different cooking and reheating methods used. Moreover, the aerobic storage of cooked pork loin under a refrigerated condition also increased the formation of cholesterol oxides on reheating.

• 한국컴퓨터정보학회논문지
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• 제11권2호
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• pp.159-167
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• 2006

립리딩은 잡음이 있는 환경에서 음성 인식 시스템의 성능 향상을 위한 한 방법으로 제안되었다. 기존의 논문들이 소프트웨어 립리딩 방법을 제안하는 것에 반하여, 본 논문에서는 실시간 립리딩을 위한 하드웨어 설계를 제안한다. 실시간 처리와 구현의 용이성을 위하여 본 논문에서는 립리딩 시스템을 이미지 획득 모듈, 특징 벡터 추출 모듈, 인식 모듈의 세 모듈로 분할하였다. 이미지 획득 모듈에서는 CMOS 이미지 센서를 사용하여 입력 영상을 획득하게 하였고, 특징 벡터 추출 모듈에서는 병렬 블록매칭 알고리즘을 이용하여 입력영상으로부터 특징벡터를 추출하도록 하였고, 이를 FPGA로 코딩하여 시뮬레이션 하였다. 인식 모듈에서는 추출된 특징 벡터에 대하여 HMM 기반 인식 알고리즘을 적용하여 발성한 단어를 인식하도록 하였고, 이를 DSP에 코딩하여 시뮬레이션 하였다. 시뮬레이션 결과 실시간 립리딩 시스템이 하드웨어로 구현 가능함을 알 수 있었다.

• 한국환경성돌연변이발암원학회지
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• 제22권1호
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• pp.12-21
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• 2002

Genetic polymorphisms of the renin-angiotensin system (RAS) have been associated with hypertension in various ethnic groups, but no relation between these polymorphisms and hypertension has yet been systematically evaluated. To assess the relationship between allelic variation of RAS genes and hypertension, we performed the case-control studies using genetic markers in Korean normotensives and hypertensives. The allele and genotype frequencies of RAS genes in Korean population were not significantly different between normotensives and hypertensives. To investigate the distribution of allele frequencies among various populations, the data obtained in this study were compared to those in other ethnic groups studied previously. Except for T174M polymorphism of angiotensinogen (AGT) gene, allele frequencies of RAS genes were different among racial groups. The reason for these differences may be due to the difference in various genetic or environmental background or due to the effects by various sample size studied. In addition, it can be emphasized that carefully designed studies are required to minimize the ethnic heterogeneity of the case and control populations.

• 한국환경성돌연변이발암원학회지
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• 제22권1호
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• pp.39-46
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• 2002

Obesity is a complex metabolic disorder with a strong genetic component. There are many candidate genes for obesity and its related phenotypes. We studied genetic variations between Korean obese and lean groups. Polymorphisms investigated were the Msp I polymorphism of the $\alpha$$_{2A}$-adrenergic receptor ($\alpha$$_{2A}$-AR) gene, the Mnl I polymorphism of the $\alpha$$_2$-adrenergic receptor ($\alpha$$_2$-AR) gene, the BstO I polymorphism of the $\beta$$_3$-adrenergic receptor ($\beta$$_3$-AR) gene, the Pml I polymorphism of the lamin A/C (LMNA) gene, the Hga I polymorphism of the clearance receptor (NPRC) gene, the Msp I polymorphism of the leptin gene, BclI polymorphism of the uncoupling protein 1 (UCPI) gene and the Hha I polymorphism of the fatty acid binding protein 2 (FABP2) gene. Among these genetic markers, Pml I polymorphism at the LMNA gene and Bcl I polymorphism at the UCP1 gene were significantly associated with obesity. However, further studies are required whether thease findings are reproduced in large population, although two polymorphisms might be useful as genetic markers in the ethiology of obesity in Korean population.ion.

• 한국병원경영학회지
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• 제25권3호
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• pp.78-86
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• 2020

Purposes: This study purposed to identify factors influencing the composite quality score from the quality assessment program for long-term care hospitals Methodology: The study variables was obtained from HIRA(Health Insurance Review and Assessment Service): the composite quality scores and hospital variables such as number of doctors, nurses, beds, medical technicians, medical equipments, administrative region, ownerships from 3rd (2010) to 7th (2018) quality assessment program. National Statistical Portal(www.kosis.go.kr) provided the number of senior citizens aged over 65 in city·county·district area. SAS 9.4 was used for the data processing and used to analyze the data. Findings: The results showed that composite quality score increased past 9 years. Hospital variables such as number of doctor, nurse, medical technicians, bed and public hospitals had significant positive relationship with the composite quality score. Administrative region(district) showed higher scores compare to that of city. Compare to the score of quality assessment year(2010), as the assessment year move to 2012, 2013, 2015, 2018, results showed higher significant positive coefficients. Practical Implication: Continuously improve the performance of long-term care hospitals, current quality assessment program are needed to update their system such as adopting indicators measuring the service process, or compensating the cost for quality assessment program. It will enable to provide more reasonable and accurate performance assessment scores.

• Bulletin of the Korean Chemical Society
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• 제33권7호
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• pp.2213-2218
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• 2012

Efficient synthetic routes were developed to prepare a sizable amount (4-15 grams) of the chiral epoxides 4-6 as versatile intermediates for the synthesis of aspartyl protease inhibitors of therapeutic interest such as HIV protease and ${\beta}$-secretase. Oxidative cleavage of the C(2)-C(3) double bond of L-ascorbic acid followed by functional group manipulation led to the preparation of the epoxide 10, which was opened with an azide to yield a common aziridine intermediate 12. Through opening of the aziridine ring of 12 with either a carbon or a sulfur nucleophile, chiral epoxide precursors 4-6 could be prepared for various HIV protease inhibitors. Except for the final low melting epoxides 5 and 6, all intermediates were obtained as crystalline solids, thus the synthetic pathway can be easily applied to a large-scale synthesis of the chiral epoxides.

• 한국방재학회:학술대회논문집
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• 한국방재학회 2008년도 정기총회 및 학술발표대회
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• pp.751-754
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• 2008

최근의 집중호우로 소하천의 피해가 빈번해짐에 따라 치수적 안전성을 확보함과 동시에 환경생태기능 및 경관보존 측면을 반영한 하천정비공법 개발이 필요하게 되었다. 본 연구에서는 국내 소하천에 적용가능한 자연형 하천정비공법 개발을 위해 $2002\sim2007$년에 걸쳐 전국의 7개 시범소하천을 대상으로 모니터링을 실시하였다. 시범소하천에 대한 정비공사 시행 후, 수변생태계에 교란이 발생하였으나 자연형호안공법 적용으로 생태계의 복원 정도 및 속도는 양호한 것으로 조사되었다. 그러나 국내 적용사례가 많은 호안공법에 대한 실측자료가 부족하여, 공법별 하천복원 및 허용소류력 검토가 어려운 실정이다. 따라서 향후 지속적인 모니터링 사업을 통해 보다 효과적인 자연형 호안공법을 제시해야할 것이다.