• 제목/요약/키워드: Sampling Rate

검색결과 1,670건 처리시간 0.038초

임상시험 대상자 모집 광고에 대한 정부의 규제 효과 (The Effect of Regulation on Recruitment Advertising for Clinical Trial Subjects in Korea)

  • 김현진;손현순
    • 한국임상약학회지
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    • 제32권3호
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    • pp.166-177
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    • 2022
  • Background: Recently clinical trials have expanded extensively in Korea; thus, ensuring the rights of subjects participating in clinical trials is imperative. Accordingly, national regulations on subject recruitment advertisement were enforced from October 25, 2018. In this study, the effect of this regulation was evaluated by analyzing the difference in the provision of information before and after enforcement of the regulation. Methods: Recruitment advertisements for clinical trial subjects 3 years before and after enforcement of the regulation were collated by the significance sampling approach. Print-based (newspapers, buses, and subways) and web-based (clinical trial center websites and online platforms) materials for recruitment in clinical trials of phase 1 to 4 for investigational drugs, medical devices, and oriental medicine were considered. Chi-square tests were conducted for inter-group comparisons. SPSS version 26 was employed for statistical analyses. Results: A total of 137 advertisements were collected comprising 60 pre- and 77 post-regulation enforcement. The overall rate of delivery of critical information in advertisements increased significantly from 47.5% before regulation to 93.2% after regulation enforcement. Particularly, details on expected adverse events augmented significantly (p<0.001). Benefits from participation in clinical trial reduced significantly from 88.3% to 70.1% (p<0.05). As the information provision amplified, the inclusion of professional terms increased. Conclusions: Enforcement of regulations has led to a surge in the amount of information and challenging terms contained in advertisements for recruiting subjects. Therefore, additional efforts are required by subjects to completely understand the information provided in the advertisements.

GAN 오버샘플링 기법과 CNN-BLSTM 결합 모델을 이용한 부정맥 분류 (Arrhythmia Classification using GAN-based Over-Sampling Method and Combination Model of CNN-BLSTM)

  • 조익성;권혁숭
    • 한국정보통신학회논문지
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    • 제26권10호
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    • pp.1490-1499
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    • 2022
  • 부정맥이란 심장이 불규칙한 리듬이나 비정상적인 심박동수를 갖는 것을 말하며, 뇌졸중, 심정지 등을 유발하거나 사망에도 이를 수 있는 만큼, 조기 진단과 관리가 무엇보다 중요하다. 본 연구에서는 심전도 신호의 QRS 특징 추출에 적합한 CNN과 기존 LSTM의 직전 패턴의 수렴 한계를 해결할 수 있는 BLSTM을 연결한 CNN-BLSTM 결합 모델을 이용한 부정맥 분류 방법을 제안한다. 이를 위해 먼저 전처리 과정을 통해 잡음을 제거한 심전도 신호에서 QRS 특징점을 검출하고 단일 비트 세그먼트를 추출하였다. 이때 데이터의 불균형 문제를 해결하기 위해 GAN 오버샘플링 기법을 적용하였다. 이 후 합성곱 계층을 통해 부정맥 신호의 패턴을 정밀하게 추출하도록 구성하고 이를 BLSTM의 입력으로 사용한 후 매개변수를 학습시키고 검증 데이터로 학습 모델을 평가한 후 부정맥 분류의 정확도를 확인하였다. 제안한 방법의 우수성을 입증하기 위해 MIT-BIH 부정맥 데이터베이스를 이용하여 분류의 정확도, 정밀도, 재현율, F1-score를 비교하였다. 성능평가 결과 각각 99.30%, 98.70%, 97.50%, 98.06%로 우수한 분류율을 나타내는 것을 확인할 수 있었다.

Ethnic Variation and Its Association With Malaria Awareness: A Cross-sectional Study in East Nusa Tenggara Province, Indonesia

  • Guntur, Robertus Dole;Kingsley, Jonathan;Islam, Fakir M. Amirul
    • Journal of Preventive Medicine and Public Health
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    • 제55권1호
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    • pp.68-79
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    • 2022
  • Objectives: This study investigated associations between ethnicity and malaria awareness in East Nusa Tenggara Province (ENTP), Indonesia. Methods: A community-based cross-sectional study was conducted upon 1503 adults recruited by multi-stage cluster random sampling. A malaria awareness questionnaire was used to collect data, according to which participants were classified as aware or unaware of malaria. Logistic regression was applied to quantify the strength of associations of factors with malaria awareness. Results: The participation rate in this study was high (99.5%). The participants were distributed relatively evenly among the Manggarai, Atoni, and Sumba ethnicities (33.0, 32.3, and 30.2%, respectively). Malaria awareness was significantly different amongst these groups; it was most common in the Manggarai ethnicity (65.1%; 95% confidence interval [CI], 59.9 to 70.3) and least common in the Sumba ethnicity (35.0%; 95% CI, 27.6 to 42.4). The most prominent factor influencing the malaria awareness in the Sumba and Manggarai ethnicities was education level, whilst it was socioeconomic status (SES) in the Atoni ethnicity. The likelihood of malaria awareness was significantly higher in adults with an education level of diploma or above (adjusted odds ratio [aOR], 21.4; 95% CI, 3.59 to 127.7 for Manggarai; aOR, 6.94; 95% CI, 1.81 to 26.6 for Sumba). Malaria awareness was significantly more common amongst high-SES adults in the Atoni group (aOR, 24.48; 95% CI, 8.79 to 68.21). Conclusions: Low education levels and low SES were prominent contributors to lower levels of malaria awareness in rural ENTP. Interventions should focus on improving malaria awareness to these groups to support the Indonesian government's national commitment to achieve a malaria elimination zone by 2030.

돈사용 스크러버 및 바이오커튼의 축산악취 저감효과 분석 (Evaluation of Livestock Odor Reduction Efficiency for Odor Reduction Systems in Domestic Pig Farms)

  • 이민형;여욱현;이인복;정득영;이상연;김준규;크리스티나;최영배;강솔뫼
    • 한국농공학회논문집
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    • 제64권6호
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    • pp.77-86
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    • 2022
  • Various odor reduction systems are being operated at pig houses to improve livestock odor issues. However, the quantitative evaluation of odor reduction efficiency is not sufficiently conducted. The analysis of factors that affect the reduction efficiency also has not been sufficiently conducted. Therefore, in this study, the reduction efficiency of representative odor reduction facilities (bio-curtain, scrubber) operated by domestic pig houses was evaluated. The odor reduction efficiency was evaluated by sampling the air before and after the odor reduction facility in 6 pig houses. Livestock odors were evaluated for complex odors, ammonia, hydrogen sulfide, and VOC. To find factors for reduction efficiency, temperature, humidity, pH of washing resolution, type of washing water, and ventilation rate was measured. As a result, it was found that the scrubber system had the highest reduction efficiency. The reduction efficiency was found to be affected by the scrubber's washing resolution, filler, operating conditions, and size. Bio-curtains may have problems such as deterioration of fan performance due to ventilation fan load, groundwater pollution, and excessive use of groundwater.

Infestation of the Longhorned Beetles Species (Cerambycidae) on Acacia seyal Del var. seyal in the Gum Arabic Belt of Sudan

  • Eisa, Maymoona Ahmed;Adam, Yahia Omar
    • Journal of Forest and Environmental Science
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    • 제26권2호
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    • pp.113-116
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    • 2010
  • The Acacia seyal Del. var. seyal belongs to family Mimosaceae is known locally as gum Talha tree. It is a multipurpose tree species occurs throughout the African gum belt in Savannah mostly in pure forest. In Sudan it thrives on heavy clay soils that receive an annual rainfall between 400-800 mm. It is an important source of rural energy (fuelwood and charcoal) and forage. As mentioned by Nair (2007) the economic damage causes by insect in natural forest often difficult to judge due to no enough research attention The tree is frequently affected by biotic factors among them the insect pests. During a survey in the 1980's the tree was severely infested by the longhorned beetles (Cerambycidae) severely infesting other Acacia species, but the ecological data are overlooked. Therefore, the objective of the study was to assess infestation characteristics and to determine environmental factors triggering the attack of longhorned beetles. A temporary random sampling technique was applied to observe the damage characteristics of the longhorned beetles on tree species during May-July 2007. Five sample plots occupies by A. seyal were taken in Kordofan region directly observed for the presence of hole of emergence of the longhorned beetles, presence of dusts, presence of insect stages, girdling as well as other characteristics of damage. The study results indicate that the infestation rate of trees in the sampled sites ranged between zero and 23.08%. Further ecological researches are recommended.

이단 필터 샘플러에 의한 대기 부유분진의 포집 및 금속 성분의 계절별 거동에 관한 연구 (Aerosol Sampling with Two Stage Filter Sampler and Seasonal Variation of Metal Components in the Atmosphere)

  • 이용근;김남훈;명노승;황규자
    • 한국대기환경학회지
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    • 제4권2호
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    • pp.20-27
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    • 1988
  • A simple two stage aerosol filter sampler which allows simultaneous and fractional collection of two different-size particles, coarse and fine, was constructed and applied to the collection of Seoul atmospheric particulate for inorganic analysis. The sampler consist of two 47-mm diameter filter holder, a pneumatic pump, and a flowmeter. Filtering rate normally runs around 20$\ell$/min for 8 hrs. Using the sampler, a series of seasonal aerosol samples were collected from June 1986 to March 1988 at Yonsei University campus, Seoul and subsequently analysed for ten environmentally important metals using an atomic absorption spectrometer and an inductively coupled plasma emission spectrometer. The analysed metals are Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb, V, and Zn. The analytical results showed the following order of metal abundance; Al > Fe > Zn > Pb > Mn > Cu > V > Ni > Cr > Cd. Based upon their size distribution pattern, the analyzed matals could be clasified into two groups, those present primarily in coarse particle and those in fine particle. Fe, Al, Mn, V, and Cr belong to the former group while the rest to the latter. Most metal concentration were highest in spring or winter, and lowest in autumn. Statistical analysis showed strong correlations between Al and Fe, Pb and Zn, and Cu and Mn.

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AoIP/UDP 기반 오디오 통신의 다중 채널 Low-Latency 구현 (Low-Latency Implementation of Multi-channel in AoIP/UDP-based Audio Communication)

  • 양승도;최진구
    • 한국인터넷방송통신학회논문지
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    • 제23권3호
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    • pp.59-64
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    • 2023
  • 화재 재난방송 시스템에서는 아날로그, 디지털, 네트워크 디지털 전관 방송 시스템으로 나뉘며, 네트워크 디지털 전광 방송 시스템에서 중요한 사양은 낮은 대기 시간(Low-latency), 높은 샘플링 레이트, 다채널 입출력이다. 기존에 데이터링크 층의 MAC 주소 기반으로 구별하는 AoE(Audio over Ethernet) 방법을 널리 사용하고 있다. 그러나 이 방법은 복잡성과 비용이 증가하는 문제가 있다. 이에 본 제안은 AoIP(Audio over Internet Protocol)/UDP 방식으로 별도의 중복적인 네트워크가 필요 없이 IP(Internet Protocol) 주소로 손쉽게 구별하는 통신을 할 수 있어 네트워크를 자유롭게 사용 구성하고 복잡도를 낮추어 비용을 낮출 수 있도록 제안한다. AoIP/UDP 방식으로 구현 후 실험결과 2.66ms 대기 시간 성능으로 동등한 성능으로 비용의 개선함을 보였다.

전극의 전기분해 용출을 통한 해성점토의 개량에 관한 연구 (A Study on Improvement of Marine Clay through the Leaching Effect of Electrolyte Reaction in Electrode)

  • 한상재;김수삼;김종윤
    • 대한토목학회논문집
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    • 제26권2C호
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    • pp.89-98
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    • 2006
  • 본 연구에서는 해성점토의 전단강도를 증진시킬 목적으로 철과 알루미늄 전극을 직접 삽입한 후 전극을 분해하여 지반 고결화 효과를 유발하였다. 이를 위해 남해안에서 채취한 실제 해성점토에 대해 실내 토조를 이용한 파일럿 실험을 실시하였고, 각각 철과 알루미늄을 삽입한 후 일정 고전류(2.5A)를 적용시켰다. 고결화에 의한 영향을 파악하고자 실험 종료 후에는 콘관입시험기를 이용하여 비배수 전단강도를 측정하였으며, 위치별 함수비와 pH 및 전기전도도를 측정하여 철과 알루미늄의 전극분해에 의한 고결화 효과를 간접적으로 판단하였다. 철 전극 전기분해 실험 결과, 양(+)극부 근처에서의 함수비는 초기에 비해 35% 감소하였고, 음극부 근처에서는 13% 증가하였으나, 양극부에서 용출된 철 이온과 흙 입자의 고결화 작용에 의해 전체적으로 측정된 전단강도는 초기에 비해 상당히 증가하였다. 또한 알루미늄 전극을 이용하였을 경우, 철에 비해 비교적 균일한 전단강도 증진효과가 나타났으며, 그 개량정도 역시 더 크게 나타났다.

타이어 화재 대응 소방관들의 휘발성유기화합물 노출 평가 (Firefighters' Exposure to Volatile Organic Compounds in Tyre Fire)

  • 김원;최인자;조영환;정혜영;권지운;이소연
    • 한국산업보건학회지
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    • 제33권4호
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    • pp.385-394
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    • 2023
  • Objectives: Firefighters could be exposed to a range of toxic chemicals during firefighting. When tyre burns, various toxic chemicals including volatile organic compounds(VOCs) could be emitted. In this study, the researchers assessed the VOC exposure of firefighters during tyre fire suppression through biomonitoring. Methods: There was a big tyre fire on 12 March 2023. Of the responding firefighters, we recruited 14 participants to collect their urine after firefighting. One week later, researchers collected firefighters' urine again right after their off-duty period. We analyzed each metabolite of benzene, toluene, xylene, and styrene in urine and compared their exposure level based on sampling time. Results: The detection rate for metabolite of benzene, toluene, styrene, and xylene in urine sampled at each time was 43%-64%, 100%, 86%-100%, and 100%, respectively. Except for the benzene, metabolite levels measured in urine after firefighting were similar to that from off-duty period. However, the median concentration of benzene metabolite in urine sampled after firefighting was three times higher compared to that from off-duty period(34.2 ㎍/g crea. and 10.9 ㎍/g crea., respectively.) The estimated airborne concentration of benzene calculated from metabolite level in urine was 0.16 ppm, which exceeded the recommended exposure level set by the National Institute for Occupational Safety and Health. Conclusions: This study shows that firefighters could be exposed to the high level of VOCs including benzene during their firefighting especially at tyre fire. These results could be used as a valuable data to prove firefighters' exposure to hazardous chemicals during their duty.

Korea Pathfinder Lunar Orbiter Magnetometer Instrument and Initial Data Processing

  • Wooin Jo;Ho Jin;Hyeonhu Park;Yunho Jang;Seongwhan Lee;Khan-Hyuk Kim;Ian Garrick-Bethell;Jehyuck Shin;Seul-Min Baek;Junhyun Lee;Derac Son;Eunhyeuk Kim
    • Journal of Astronomy and Space Sciences
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    • 제40권4호
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    • pp.199-215
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    • 2023
  • The Korea Pathfinder Lunar Orbiter (KPLO), the first South Korea lunar exploration probe, successfully arrived at the Moon on December, 2022 (UTC), following a 4.5-month ballistic lunar transfer (BLT) trajectory. Since the launch (4 August, 2022), the KPLO magnetometer (KMAG) has carried out various observations during the trans-lunar cruise phase and a 100 km altitude lunar polar orbit. KMAG consists of three fluxgate magnetometers capable of measuring magnetic fields within a ± 1,000 nT range with a resolution of 0.2 nT. The sampling rate is 10 Hz. During the originally planned lifetime of one year, KMAG has been operating successfully while performing observations of lunar crustal magnetic fields, magnetic fields induced in the lunar interior, and various solar wind events. The calibration and offset processes were performed during the TLC phase. In addition, reliabilities of the KMAG lunar magnetic field observations have been verified by comparing them with the surface vector mapping (SVM) data. If the KPLO's mission orbit during the extended mission phase is close enough to the lunar surface, KMAG will contribute to updating the lunar surface magnetic field map and will provide insights into the lunar interior structure and lunar space environment.