• 제목/요약/키워드: Sample array

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Microfluidic Array for Simultaneous Detection of Antigen-antibody Bindings (항원-항체 결합의 동시 검출을 위한 미세 유체 어레이)

  • Bae, Young-Min
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.4
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    • pp.102-107
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    • 2011
  • In this paper, a microfluidic array biochip for simultaneously detecting multiple antigen-antibody bindings was designed and implemented. The biochip has the single channel in which microreaction chambers are serially connected, and the antibody-coated microbeads are packed in each microreaction chamber. In addition, the weir structure was fabricated in the microchannel using the gray-scale photolithography in order to trap the microbeads in the microreaction chamber. Three kinds of antibodies were chosen, and the antibodies were immobilized onto the microbeads by the streptavidin-biotin conjugation. In the experiment, as the fluorescence-labeled antigens were injected into the microchannel, the antigen-antibody bindings were completed in 10 minutes. When the solution with multiple antigens was injected into the microchannel, it was observed that the fluorescence intensity increased in only the corresponding microreaction chambers with few non-specific binding. The microfluidic array biochip implemented in this study provides, even with the consumption of tiny amount of sample and fast reaction time to simultaneously detect multiple immunoreactions.

Development of the Planar Active Phased Array Radar System with Real-time Adaptive Beamforming and Signal Processing (실시간으로 적응빔형성 및 신호처리를 수행하는 평면능동위상배열 레이더 시스템 개발)

  • Kim, Kwan Sung;Lee, Min Joon;Jung, Chang Sik;Yeom, Dong Jin
    • Journal of the Korea Institute of Military Science and Technology
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    • v.15 no.6
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    • pp.812-819
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    • 2012
  • Interference and jamming are becoming increasing concern to a radar system nowdays. AESA(Active Electronically Steered Array) antennas and adaptive beamforming(ABF), in which antenna beam patterns can be modified to reject the interference, offer a potential solution to overcome the problems encountered. In this paper, we've developed a planar active phased array radar system, in which ABF, target detection and tracking algorithm operate in real-time. For the high output power and the low noise figure of the antenna, we've designed the S-band TRMs based on GaN HEMT. For real-time processing, we've used wavelenth division multiplexing technique on fiber optic communication which enables rapid data communication between the antenna and the signal processor. Also, we've implemented the HW and SW architecture of Real-time Signal Processor(RSP) for adaptive beamforming that uses SMI(Sample Matrix Inversion) technique based on MVDR(Minimum Variance Distortionless Response). The performance of this radar system has been verified by near-field and far-field tests.

Study on Beamforming of Conformal Array Antenna Using Support Vector Regression (Support Vector Regression을 이용한 컨포멀 배열 안테나의 빔 형성 연구)

  • Lee, Kang-In;Jung, Sang-Hoon;Ryu, Hong-Kyun;Yoon, Young-Joong;Nam, Sang-Wook;Chung, Young-Seek
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.11
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    • pp.868-877
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    • 2018
  • In this paper, we propose a new beamforming algorithm for a conformal array antenna based on support vector regression(SVR). While the conventional least squares method(LSM) considers all sample errors, SVR considers errors beyond the given error bound to obtain the optimum weight vector, which has a sparse solution and the advantage of the minimization of the overfitting problem. To verify the performance of the proposed algorithm, we apply SVR to the experimentally measured active element patterns of the conformal array antenna and obtain the weights for beamforming. In addition, we compare the beamforming results of SVR and LSM.

Multi-illumination digital holographic microscopy

  • Phan, Anh-Hoang;Kim, Nam;Park, Jae-Hyeung
    • Proceedings of the Optical Society of Korea Conference
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    • 2009.10a
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    • pp.323-324
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    • 2009
  • In this paper, we use multi-point sources to illuminate the sample in digital holographic microscopy. The resolution of digital holographic microscopy is enhanced without shifting the CCD camera. The specimen is illuminated from many directions by using multi-point sources which are easily created by a lens-array. The high frequency information of specimen can be captured at a fixed position of CCD camera. All information is then synthesized to increase the resolution.

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Fluorescece Microscope using Total Internal Reflection for Measuring Biochip (내부 전반사 방식에 의한 바이오칩 측정 장비)

  • Bae, Soo-Jin;Kang, Uk
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.9
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    • pp.1694-1698
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    • 2007
  • This study suggests a new fluorescence microscope to observe micro-samples within fluorophore in a variety of biomedical fields including the fluorescence analysis of a biochip, such as a DNA micro-array. A fluorescence microscope is a device for irradiating light onto a micro-object, executing an excitation and fluorescence emission process. In this study, it adopts a total internal reflection fluorescence(TIRF) method to excite a whole micro-sample substrate different from an existing way which uses an evanescent wave resulting from a total internal reflection on the micro-sample surface. Suggested TIRF microscope can reduce optical noise and obtain images with higher sensitivity thus obtain precise information about the density, quantity, location, etc. of a flurophore, and can simultaneously process separate images even when plurality of fluorophores having different excitation and fluorescent wavelength ranges is distributed, thus easily obtain information about the fluorophores.

Low Complexity Sample Matrix Inversion (SMI) Technique (낮은 복잡도를 갖는 Sample Matrix Inversion (SMI) 기법)

  • Jung, Sung-Kyu;Lee, Jung-Woo
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2010.07a
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    • pp.15-17
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    • 2010
  • 적응 어레이(adaptive array) 기법은 이동통신 시스템에서 발생하는 동일채널 간섭신호를 제거하는 데에 효과적인 기술이다. 적응 어레이 기법 중 가장 널리 이용되는 SMI 기법은 높은 성능을 보이는 데 반해 상대적으로 많은 계산량을 필요로 한다. 본 논문에서는 역행렬의 크기를 줄임으로써 SMI 기법의 복잡도를 줄이는 방법을 제안한다. 제안하는 기법은 안테나 어레이 중 받은 신호의 파워가 가장 작은 안테나를 사용하지 않음으로써 안테나 어레이의 개수를 하나 줄이는 방식을 사용한다. 시뮬레이션 결과는 제안하는 방법의 복잡도가 낮음에도 불구하고 우수한 성능을 갖는다는 것을 입증한다.

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Development of a Portable Electronic Nose System (I) - System Development - (휴대용 전자코 시스템 개발 (I) - 시스템 개발 -)

  • Lee, Jeong-Woo;Kim, Seong-Min
    • Journal of Biosystems Engineering
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    • v.33 no.5
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    • pp.333-339
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    • 2008
  • The purpose of this study was to develop a portable electronic nose system to measure volatile components of agricultural and food products. Also, a graphical operating software to control the electronic nose system and to acquire signals through the Internet was developed. An array of five commercial metal oxide gas sensors was used to detect various volatile gas components of target samples. Transient and steady state signals were analyzed to extract variables related to sample states, To find optimal operating conditions of the system, several experiments were performed with different gas chambers, vacuum pumps, gas sampling temperatures, and sample container sizes. The patterns of gas sensor signals were analysed to find effects of the various conditions.

Optimization of a fiber optic probe for non-invasive blood glucose monitoring

  • Kang, Na-Roo;Baek, Ju-Hyun;Woo, Young-Ah;Lee, Hyun-Chul;Kim, Hyo-Jin
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.407.3-408
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    • 2002
  • A portable near infrared (NIR) system which was newly integrated by our lab has been used to develop a non-invasive blood glucose monitoring. The portable NIR system includes a tungsten halogen lamp, a photo diode array type-InGaAs detector, and specialized reflectance fiber optic probes. The shape of probes is composed of two parts. one for illumination into sample and the other for receiving the radiation from sample. Three kinds of probes with different distance between illumination and receiving part. such as 0.03. 0.1. and 0.5mm, were investigated for optimization. (omitted)

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Improvement Residual Non-uniformity in Thermal Imaging System Using Correlated Double Sample Signal Processing (상관이중표본화 신호처리를 이용한 적외선 열상시스템의 잔여불균일성 개선)

  • Suk, Jung-Youp;Jang, Sung-Kun;Kim, Sung-Un;Yeou, Bo-Yeoun
    • Proceedings of the IEEK Conference
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    • 2008.06a
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    • pp.1043-1044
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    • 2008
  • In this study, a novel algorithm of the improvement residual non-uniformity (RNU) in thermal imaging system is proposed using correlated double sample signal processing. The proposed method attempts to eliminate offset variation of ROIC in IR detector causing the variation of FPA (focal plane array) temperature and suppling power. Experimental results show that the proposed method confirmed a better performance than the existing RNU system.

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Estimation Technique on the Bearings and Doppler frequencies Using the Passive Non-Uniformly Distributed Towed Line Array (수동형 비균일 선형 견인 배열 센서를 이용한 입사각 및 도플러 주파수 동시 추정 기법)

  • 강정원;이원철
    • The Journal of the Acoustical Society of Korea
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    • v.17 no.2
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    • pp.32-42
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    • 1998
  • 본 논문은 비균일 분포 수동형 견인 배열 센서를 사용하여 입사각 추정은 물론, 도 플러 주파수를 동시에 추정해내기 위한 기법을 제안한다. 균일 선형 센서 배열을 사용하는 전통적인 수동형 견인 센서 배열 처리기법은 센서간의 등 간격 구조 및 단순한 표본 과정에 기인하여 활용 분야의 한계성을 가지며, 주된 응용 분야가 방사된 음향신호의 입사각을 추 정하는데만 국한되어 사용될 수 있다는 문제점을 내포하고 있다. 이러한 사실 때문에, 수중 천해 환경 하에서 견인함의 등속 이동에 의해 발생하는 도플러 주파수들에 대한 정보는 목 표물에 대한 식별이나 음향신호 전달 경로의 모델링에 중요한 매개변수로 작용하며, 일반적 인 수동형 견인 센서 배열의 사용에 의한 처리 방식으로는 이러한 매개변수의 추출이 불가 능하게 된다. 본 논문은 이러한 제한성을 극복하고 방사 신호들의 개별적인 입사각 및 도플 러 주파수의 동시 추정을 가능케하도록 비균일 분포의 선형 센서 배열과 Sample Skipping 기법(Sample Skipping Technique;SST)을 적용한 새로운 형태의 수동형 견인 배열 센서 처 리 기법을 제안한다.

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