• Food Science and Biotechnology
• /
• 제18권4호
• /
• pp.842-848
• /
• 2009

The purpose of this study was to determine the extent of domoic acid (DA) a potent neurotoxin, responsible for the syndrome amnesic shellfish poisoning (ASP) contamination of various species of bivalve shellfish purchased from fish market in Korea and the implications for food safety. Liquid chromatography (LC) methods were applied to quantify DA in shellfish after sample clean-up using solid-phase extraction (SPE) with strong anion exchange (SAX) cartridges. Toxin detection was achieved using photodiode array ultraviolet (LC-UV) and electrospray ionization-mass (LC-ESI-MS). DA was identified in 4 bivalve shellfishes of 872 shellfishes collected from March, 2006 to October, 2007 in Korea. DA amount of 3 surf clams (Mactra veneriformis) collected at Seoul, Daejeon, and Daegu were 4.13, 1.99, and 1.94 mg/kg, respectively. DA amount of 1 pink butterfly shell (Peronidia venulosa) collected at Seoul was 3.02 mg DA/kg. The amounts of DA that were present in 4 bivalve shellfishes were within EU guideline limits for sale of shellfish (20 mg DA/kg).

• 한국음향학회지
• /
• 제20권7호
• /
• pp.94-100
• /
• 2001

적응 정합장처리에서 어레이의 센서 수보다 부족한 신호단편 수로 표본 공분산행렬을 구성할 경우 행렬 계수의 부족으로 행렬의 역변환에 문제가 발생된다. 이를 해결하기 위해 표본 공분산행렬의 대각성분에 일정한 값을 더하거나 고유분해와 같은 기법을 사용하나, 그 결과로 프로세서 출력에서는 바이어스가 발생된다. 본 논문은 고정음원에서 신호단편의 수에 따른 적응 프로세서 출력의 바이어스와 음원 위치 추정 결과를 고찰하기 위해 표본 공분산행렬의 대각성분에 일정한 값을 첨가하는 방법으로 최소분산 기법을 사용하여 수치실험과 실측 자료를 분석하였다. 그 결과 센서 수보다 많은 신호단편을 사용하는 것이 바이어스가 적으며, 음원 위치 추정에서도 좋은 성능을 보였다.

• 한국주조공학회지
• /
• 제32권2호
• /
• pp.65-74
• /
• 2012

In this paper, we present the results of our studies on optimal die design towards development of a vacuum die casting process to fabricate fuel cell bipolar plate with micro-channel array. Cavity and overflow shape is designed by computational filling analysis of MAGMA soft. Optimal die design consists of seven overflows at the end of cavity and three overflows at each side wall of cavity. The molten metal that passed the gate and reached the side wall flowed into the side overflow, no turbulent flow occurred, and the filling behavior and velocity distribution were uniform. In addition, partially solidified molten metal passing through the channel was perfectly eliminated by overflow without back-flow. When vacuum pressure, injection speed of low and high region was 300 mbar, 0.3 m/s and 2.5 m/s respectively with Silafont 36 die casting alloy, sound sample without casting defects was obtained. The experimental results are nearly consistent with simulation results.

• 대한원격탐사학회:학술대회논문집
• /
• 대한원격탐사학회 2004년도 Proceedings of ISRS 2004
• /
• pp.601-603
• /
• 2004

Multi-Spectral Camera(MSC) is a payload on the KOMPSAT -2 satellite to perform the earth remote sensing. The instrument images the earth using a push-broom motion with a swath width of 15 km and a ground sample distance (GSD) of 1 m over the entire field of view (FOV) at altitude 685 Km. The instrument is designed to have an on-orbit operation duty cycle of $20\%$ over the mission lifetime of 3 years with the functions of programmable gain! offset and onboard image data compression/storage. MSC instrument has one(1) channel for panchromatic Imaging and four(4) channel for multi-spectral Imaging covering the spectral range from 450nm to 900nm using TDI CCD Focal Plane Array (FPA). In this paper, the configuration, the interface of MSC hardware and the MSC operation concept are described. And the method of the MSC calibration are described and the design of MSC calibration operation to measure the change of MSC after Launch & Early Operation(LEOP) and normal mission operations are discussed and analyzed.

• The Journal of the Acoustical Society of Korea
• /
• 제20권4E호
• /
• pp.52-60
• /
• 2001

This paper describes real time implementation of subband sound localization system on a floating-point DSP TI TMS320C31. The system determines two dimensional location of an active speaker in a closed room environment with real noise presents. The system consists of an two microphone array connected to TI DSP hosted by PC. The implemented sound localization algorithm is Subband CPSP which is an improved version of traditional CPSP (Cross-Power Spectrum Phase) method. The algorithm first split the input speech signal into arbitrary number of subband using subband filter banks and calculate the CPSP in each subband. It then averages out the CPSP results on each subband and compute a source location estimate. The proposed algorithm has an advantage over CPSP such that it minimize the overall estimation error in source location by limiting the specific band dominant noise to that subband. As a result, it makes possible to set up a robust real time sound localization system. For real time simulation, the input speech is captured using two microphone and digitized by the DSP at sampling rate 8192 hz, 16 bit/sample. The source location is then estimated at once per second to satisfy real-time computational constraints. The performance of the proposed system is confirmed by several real time simulation of the speech at a distance of 1m, 2m, 3m with various speech source locations and it shows over 5% accuracy improvement for the source location estimation.

• 대한인간공학회:학술대회논문집
• /
• 대한인간공학회 1987년도 춘계학술대회논문집
• /
• pp.143-148
• /
• 1987

The Design of automotive IP must be designed for improving safety, and for satisfying the consumer's preference and for enlarging the usability of various gauges and information displaydevices. Also, these objects become more important by regarded and will be treated very sensitively for the next-generation vehicle concepts. Therefore, Automotive IP must be designed to adjust these trends, besides accord with car-inner lifestyle. One of these concept's designs is to apply Human Sensibility Ergonomics. This study suggestes the driver-centered design of the IP components that focused on the audio unit and HVAC(Heat and Ventilation Air Conditioner) through cognitive experiment. Primarily, analyzed components of IP in use, then, combined these components (especially, the number and arry of buttons, the position of LCD panel, etc.) nd designed some sample images(prototypes) the same as real size. After the subjects looked at the sam ples at the interval of 0.2/0.4/0.6 seconds, subjects should fill out the given forms from their memory. Then, the optimal prototype of IP was designed in respect to the correctness of cognition. The results will show the basic guideline of optimal design of IP that in the case of aaudio unit, the position of LCD, the array and the number of channel, in the case of HVAC, the position of LCD, TEMP button type and other button types.

• Journal of Oral Medicine and Pain
• /
• 제24권2호
• /
• pp.181-187
• /
• 1999

The most important progress in diagnostic sciences is the increased sensitivity and specificity in diagnostic procedures due to the development of newer micromethodologies and increasing availability of immunological and molecular biological reagents. The outcome of researches in this field has already provided DNA probes and antibodies which can be used for diagnosing various kinds of diseases including inherited ones. This development can be also applied to diagnose diseases in oral and maxillofacial regions. Technological advances have yielded highly sensitive test methodologies so that low analyte concentration and small sample volume are no longer limiting factors. Therefore, saliva can be useful test fluid for an array of analytes. Salivary constituents of diagnostic significance include steroid hormones, antibodies, drugs, and tumor markers. Of the proteins present in saliva, viral-specific immunoglobulins are of the greatest diagnostic interest. The development of conjugates and antigens by recombinant DNA technique and peptide synthesis is necessary for clinical application. Several kits developed for the purpose of blood testing should be modified to permit their application to saliva. The final practical outcome of researches in diagnostic sciences will be various diagnostic agents which can be used for detection of bacteria and viruses, screening and diagnosis of diseases, genetic screening for forensic individual identification. For these purposes, collaboration researches and development between institutions and companies are essential.

• 생약학회지
• /
• 제47권3호
• /
• pp.237-245
• /
• 2016

In present study, we conducted quantification analysis of phenolic compound (paeonol), monoterpene glycoside (paeoniflorin), and tannin ((+)-catechin in the 70% ethanol extracts of non-processed Moutan Radicis Cortex (MRC) and processed MRC by roasting using a high-performance liquid chromatography coupled with photodiode array detector. Three marker components were separated on Gemini $C_{18}$ analytical column and the column was maintained at $40^{\circ}C$ using two mobile phase system consisting of 1.0% (v/v) aqueous acetic acid and 1.0% (v/v) acetic acid in acetonitrile. The flow rate and injection volume were 1.0 mL/min and 10 mL. In non-processed MRC sample, the concentrations of three marker compounds, (+)-catechin, paeoniflorin, and paeonol were 0.20, 1.18, and 2.12%, respectively. On the other hand, the concentrations of the three compounds in processed MRC samples were 0.03-0.24, not detected-1.08, and 0.76-1.82%, respectively.

• Applied Microscopy
• /
• 제46권2호
• /
• pp.93-99
• /
• 2016

The thickness of specimen is an important factor in microscopic researches. Thicker specimen contains more information, but it is difficult to obtain well focused image with precise details due to optical limit of conventional microscope. Recently, a microscope unit that combines improved illumination system, which allows real time three-dimensional (3D) image and automatic z-stack merging software. In this research, we evaluated the usefulness of this unit in observing thick samples; Golgi stained nervous tissue and ground prepared bone, tooth, and non-transparent small sample; zebra fish teeth. Well focused image in thick samples was obtained by processing z-stack images with Panfocal software. A clear feature of neuronal dendrite branching pattern could be taken. 3D features were clearly observed by oblique illumination. Furthermore, 3D array and shape of zebra fish teeth was clearly distinguished. A novel combination of two channel oblique illumination and z-stack imaging process increased depth of field and optimized contrast, which has a potential to be further applied in the field of neuroscience, hard tissue biology, and analysis of small organic structures such as ear ossicles and zebra fish teeth.

• 한국식품조리과학회지
• /
• 제19권1호
• /
• pp.83-95
• /
• 2003

Investigations were conducted on the changes in carotenoids content, and quantification of cis-trans-${\beta}$-carotene Isomers in pureed and cooked carrot and spinach during storage. The isomerization and degradation of carotenoids were monitored by high-performance liquid chromatography on a C$\_$30/ reversed-phase column with diode-array detection. The results showed that lutein, ail-trans-${\beta}$-carotene, ${\alpha}$-carotene, 9-cis-${\beta}$-carotene and 13-cis-${\beta}$-carotene were present in carrot and spinach. Zeaxanthin and cryptoxanthin were present in raw spinach. The contents of lutein, zeaxanthin, cryptoxanthin, ${\alpha}$-carotene and all-trans-${\beta}$-carotene in pureed and cooked carrot and spinach decreased with increasing storage period. The 9-cis and 13-cis carotenoid isomers were the major types formed in cooked carrot during storage. Cooking was not found to alter the carotenoid profile of the sample, but increased the total amount of carotenoids compared with pured ones. This increase could be explained that cooking itself increased the extraction efficiency and inactivated the enzymes degradating carotenoids.