• 제목/요약/키워드: Sample Distribution

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A Bayesian Multiple Testing of Detecting Differentially Expressed Genes in Two-sample Comparison Problem

  • Oh Hyun-Sook;Yang Wan-Youn
    • Communications for Statistical Applications and Methods
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    • 제13권1호
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    • pp.39-47
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    • 2006
  • The Bayesian approach to multiple testing procedure for one sample testing problem proposed by Scott and Berger (2003) is extended to two-sample comparison problem in microarray experiments. The prior distribution of each gene's mean for one sample is given conditionally on the corresponding gene's mean for the other sample. Posterior distributions of interesting parameters are derived and estimated based on an importance sampling method. A simulated example is given for illustration.

PCR을 이용한 치주환자의 타액과 치은연하치태의 세균분포에 관한 연구 (The Distribution of Actinobacillus actinomycetemcomitans, Hemophilus aphrophilus and Hemophilus paraphrophilus in Subgingival Plaque and Saliva from Korean Periodontitis Patients using PCR)

  • 최옥선;안광숙;김혜진;이은숙
    • 한국치위생학회지
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    • 제2권2호
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    • pp.201-213
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    • 2002
  • The closely related species Actinobacillus actinomycetemcomitans, Hemophilus aphrophilus and Hemophilus paraphrophilus are common findings in oral microbiota. The aims of this study were to compare the distribution of three species in healthy subjects and periodontitis patients using PCR for 16s rRNA gene. The DNA was extracted from the subgingival plaque and saliva in 122 subjects for restriction enzyme analysis with Hinf I and Hha I. In case of periodontally healthy person, A. actinomycetemcomitans was predominant than H. paraphrophilus in saliva sample, but H. paraphrophilus was predominant than A. actinomycetemcomitans in subgingival plaque sample. On the contrary, in case of periodontitis patients, H. paraphrophilus was predominant than A. actinomycetemcomitans in saliva sample, but A. actinomycetemcomitans was predominant than H. paraphrophilus in subgingival plaque sample. In addition, the fact was confirmed that the distribution of A. actinomycetemcomitns of women periodontitis patients was somewhat higher than men periodontitis patients in saliva and subgingival plaque samples. We convinced that the PCR method for 16s rRNA gene was important for screening and monitoring of periodontal disease.

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Influence of Sample Preparation Method and Silver Salt Types on MALDI-TOFMS Analysis of Polybutadiene

  • Choi, Sung-Seen;Ha, Sung-Ho
    • Macromolecular Research
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    • 제16권2호
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    • pp.108-112
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    • 2008
  • Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis of nonpolar polymeric materials is affected by the sample preparation as well as the matrix and cationizing agent. This study examined the influence of silver salt types on the MALDI analysis of polybutadiene (PB). Silver trifluoroacetate (AgTFA), silver benzoate (AgBz), silver nitrate ($AgNO_3$), and silver p-toluenesulfonate (AgTS) were used as the silver salts to compare the MALDI mass spectra of PB. The mixture solution of PB and 2,5-dihydroxybenzoic acid (DHB), as a matrix dissolved in THF, was spotted on the sample plate and dried. A droplet of the aqueous silver salt solution was placed onto the mixture. The mass spectrum with AgBz showed the clear $[M+Ag]^+$ ion distribution of PB while the mass spectrum with AgTFA did not show $[M+Ag]^+$ ions but only silver cluster ions. The mass spectra with $AgNO_3$ and AgTS did not show a clear $[M+Ag]^+$ ion distribution. The difference in the formation of $[M+Ag]^+$ ions of PB depending on the silver salts was attributed to the silver cation transfer reaction between the silver salt and the matrix (DHB). The mass spectrum showed a clear $[M+Ag]^+$ ion distribution of PB when the conjugate acid of the silver salt was less acidic than the matrix.

튜브, 봉류의 와전류 탐상시 시편 변위에 의한 신호 변화 (Wobble and Nonconcentricity Effects in Eddy Current Test of Tubes or Rods)

  • 김영주;김영길
    • 비파괴검사학회지
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    • 제9권2호
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    • pp.37-41
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    • 1989
  • The purpose of this paper is to estimate the effect of wobble and nonconcentricity of tubes or rods in eddy current test with encircling test coils. Because the eddy current induced in a sample is related to the total magnetic flux linkages, the information about magnetic field distribution in a coil is important. In theoretical study, magnetic field distribution in a single turn coil was calculated and variation of impedance according to the difference of sample positions was presumed. Magnetic field intensity at inside of a solenoidal coil was measured and compared with the theoretical estimation. In experiment, impedance loci of a coil encircling an aluminum rod were measured at different sample positions. The effect of crack positions was examined at same sample positons.

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Modified Mass-Preserving Sample Entropy

  • Kim, Chul-Eung;Park, Sang-Un
    • Communications for Statistical Applications and Methods
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    • 제9권1호
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    • pp.13-19
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    • 2002
  • In nonparametric entropy estimation, both mass and mean-preserving maximum entropy distribution (Theil, 1980) and the underlying distribution of the sample entropy (Vasicek, 1976), the most widely used entropy estimator, consist of nb mass-preserving densities based on disjoint Intervals of the simple averages of two adjacent order statistics. In this paper, we notice that those nonparametric density functions do not actually keep the mass-preserving constraint, and propose a modified sample entropy by considering the generalized 0-statistics (Kaigh and Driscoll, 1987) in averaging two adjacent order statistics. We consider the proposed estimator in a goodness of fit test for normality and compare its performance with that of the sample entropy.

A Jarque-Bera type test for multivariate normality based on second-power skewness and kurtosis

  • Kim, Namhyun
    • Communications for Statistical Applications and Methods
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    • 제28권5호
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    • pp.463-475
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    • 2021
  • Desgagné and de Micheaux (2018) proposed an alternative univariate normality test to the Jarque-Bera test. The proposed statistic is based on the sample second power skewness and kurtosis while the Jarque-Bera statistic uses sample Pearson's skewness and kurtosis that are the third and fourth standardized sample moments, respectively. In this paper, we generalize their statistic to a multivariate version based on orthogonalization or an empirical standardization of data. The proposed multivariate statistic follows chi-squared distribution approximately. A simulation study shows that the proposed statistic has good control of type I error even for a very small sample size when critical values from the approximate distribution are used. It has comparable power to the multivariate version of the Jarque-Bera test with exactly the same idea of the orthogonalization. It also shows much better power for some mixed normal alternatives.

상악 유중절치의 치수치료후 치관수복에 대한 유한요소법적 분석 (FINITE ELEMENT ANALYSIS OF STRESS TRANSMITTED TO THE PULPECTOMIZED PRIMARY CENTRAL INCISOR RECONSTRUCTED BY COMPOSITE RESIN CROWN)

  • 맹명호;김용기;김종수
    • 대한소아치과학회지
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    • 제25권4호
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    • pp.717-730
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    • 1998
  • The Finite Element Analysis has been used for stress analysis of prosthesis, orthodontic or orthopedic appliances and filling materials. The primary purpose of the present studying was to evaluate the effectiveness of needle post in promoting the retention and integrity of composite crown restored on the pulpotomized primary central incisor. Three finite element models-natural tooth (Sample I), composite crown with (Sample II) and without (Sample III) needle post-were constructed and the stress distribution within each model were analyzed and compared one another. The results can be summarized as follows: 1. In sample I, the stress was shown to have distributed uniformly throughout the whole tooth even to the alveolar bone. 2. In sample II, the transmission of stress from the crown to the root area was shown to be very poor and irregular. 3. In sample III, the needle post was proved to be very effective in distributing the stress well to the aveolar bone which might help in maintaining the stability of crown restoration.

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몬테카를로 시뮬레이션에 의한 미소 비커스 경도의 Weibull 통계 해석 (Weibull Statistical Analysis of Micro-Vickers Hardness using Monte-Carlo Simulation)

  • 김선진;공유식;이상열
    • 대한기계학회논문집A
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    • 제33권4호
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    • pp.346-352
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    • 2009
  • In the present study, the Weibull statistical analysis using the Monte-Carlo simulation has been performed to investigate the micro-Vickers hardness measurement reliability considering the variability. Experimental indentation test were performed with a micro-Vickers hardness tester for as-received and quenching and tempering specimens in SCM440 steels. The distribution of micro-Vickers hardness is found to be 2-parameter Weibull distribution function. The mean values and coefficients of variation (COV) for both data set are compared with results based on Weibull statistical analysis. Finally, Monte-Carlo simulation was performed in order to evaluate the effect of sample size on the micro-Vickers hardness measurement reliability. For the parent distribution with shape parameter 30.0 and scale parameter 200.0 (COV=0.040), the number of sample data required to obtain the true Weibull parameters was founded by 20. For the parent distribution with shape parameter 10.0 and scale parameter 200.0 (COV=0.1240), the number of sample data required to obtain the true Weibull parameters was founded by 30.

Large Sample Tests for Independence and Symmetry in the Bivariate Weibull Model under Random Censorship

  • Cho, Jang-Sik;Ko, Jeong-Hwan;Kang, Sang-Kil
    • Journal of the Korean Data and Information Science Society
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    • 제14권2호
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    • pp.405-412
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    • 2003
  • In this paper, we consider two components system which the lifetimes have a bivariate weibull distribution with random censored data. Here the censoring time is independent of the lifetimes of the components. We construct large sample tests for independence and symmetry between two-components based on maximum likelihood estimators and the natural estimators. Also we present a numerical study.

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