• The Korean Journal of Pain
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• 제12권1호
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• pp.87-94
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• 1999

Backgroud: We have performed the CT-guided celiac plexus block (CPB) using anterior approach to evaluate the safety and efficacy of the procedure and to determine the role of CT. Methods: CPB were done in 10 patients (5 men and 5 women: mean age, 58.1 years) with intractable upper abdominal pain due to terminal malignancy of the stomach (n=3), pancreas (n=4), gallbladder (n=2), and liver (n=1). To permit an anterior approach, patients lay supine on the CT scan table during the procedure. One 21-guage Chiba needle was placed just anterior to the diaphragmatic crus between the celiac and superior mesenteric arteries and 10~12 ml of dehydrated alcohol was injected. Degree of pain relief following the procedure was assessed and pain was graded on a numeric rating scale (NRS) from 0 to 10. Results: The results suggest a direct relation between the degree of celiac invasion and the response to the CPB. With CT guidance, it is possible for us to direct the needle into more accurate region, allowing alcohol to be deposited in specific ganglion area. Conclusions: CT-guided CPB using an anterior approach was an easy and effective way of reducing intractable upper abdominal pain due to terminal malignancies. CT-guidance allowed precise needle placement and safe procedure. Careful classification of cases is important to predict the degree of pain relief using the grading system based on the degree of involvement of the celiac plexus.

• Journal of Pharmaceutical Investigation
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• 제39권4호
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• pp.263-267
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• 2009

The purpose of this study is to evaluate the efficacy of stipulated cleaning process, and the prohibition of cross-contamination and microbiological contamination, which inadequate cleaning in multi-production could occur, through cleaning validation of multi-purpose facility used to produce five biopharmaceutical products as sterile injection. After production of five biopharmaceutical products such as hGH, rhGCSF, rhEPO, rhFSH and rhIFN using vial filling machine, the cleaning validation such as residual analysis of active ingredients or human serum albumin, measurement of total organic carbon (TOC), residual analysis of detergent and microbiological contamination were carried out. In the case of rhGH and rhGCSF clean validations, drug residues were not detected. Furthermore, in the case of rhEPO, rhFSH and rhIFN clean validations, human serum albumin residues were not detected. At TOC (total organic carbon) analysis, all clean validations gave the TOC of about average 137.93%, not more than 150% of acceptance criteria. At sodium analysis for the checking of residues of cleaning agent, sodium residues were not detected. In sterility test, they showed no microbiological contamination of bacteria and fungi. Thus, this cleaning validation was determined as successful in protection of cross-contamination and induction of safety in multi-purpose facility.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2005년도 춘계 학술대회
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• pp.145-150
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• 2005

방사성 폐기물을 처분장에 처분하기 위해서는 처분 안전성을 확보하여야 한다. 본 연구는 간접측정 방법 중 하나인 물질수지 기법을 이용하여 방사성폐기물의 핵종재고량 평가 프로그램을 개발하였다. 개발 기법의 현장 적용평가를 위하여 고리4호기(9차계획예방정비)를 대상으로 선정하였다. 개발한 평가방법의 검증을 위해 정지수화학처리시 정화계통 내 핵종 제거량 평가자료를 바탕으로 비교평가를 수행하였다. 평가대상 핵종은 Co-60이며, 평가결과 상대오차 $1\%$미만으로 나타났다. 이와 같은 평가결과를 바탕으로 상용원전에서 제시하고 있는 해당기간 발생된 폐기물의 직접 측정 결과와 비교하였고, 그 결과 직접측정 방법에 의한 Co-60의 함유량은 본 연구의 개발기법에서 산출한 값보다 약 $50\%$ 작은 것으로 평가 하였다.

• 한국염색가공학회지
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• 제21권1호
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• pp.1-9
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• 2009

A lot of research has been made over the recent decade to develop testing packages with antimicrobial properties to improve food safety. In this study, a new method, experimental device and technology for environmental corresponding packages of polypropylene (PP) film has been developed to provide effective temperature buffering during the transport/long-term storage of grains or foodstuffs from the supplier to the market. This quantitatively optimized mixing system enabled to produce PP films with the 700$\sim$1,400d (width;1.5$\sim$3mm, thickness;0.01$\sim$0.5mm). In the whole mixing systems, the finely-granulated inorganic illite and PP virgin chip for master batch (M/B) chip was calculated by digital measurement methods, and then the M/B chip for PP film was adapted through a air jet and PP grinding method. The prepared PP film was characterized with tensile strength and elongation, far infrared radiation (FIR) emissivity, antimicrobial activity and deodorization properties. The results revealed that the two differently grain-sized illite could be show homogeneously dispersed on PP chip surface, and as the increasing of illite content, the FIR emissivity and the anion emission rate of film was increasingly improved. In both of 325 and 1,500 mesh-sized illite contained PP chip, of course the antimicrobial activity was good. But the ultimate deodorization rate for ammonia gas of PP film were found to be approximately the same.

• 한국치위생학회지
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• 제12권1호
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• pp.27-35
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• 2012

Objectives : This study was performed to provide the basic data for oral health of infants, through the comparison of Streptococcus mutans activities(the representative bacteria of initial dental caries), in main nutritional foods for infants: breast milk, milk powder, and soya milk. Methods : The study targeted 30 infants and the saliva was sampled after the oral examination. The pH of sampled saliva was measured; and the sample of 'the saliva', 'the saliva and breast milk', and 'the saliva and formula milk' by researcher were produced; and the measurement was repeated 7 times. Results : As a result of examining the change of colony number of Streptococcus mutans by hour, the bacterial activity took in the source of nutrition took place in the first place; and in the group with dental caries, breast-feeding at night occurreds most frequently. Due to the combined activities, such as the increase in the contact time, the existence rate of dental caries appeared high. However, as the improvement of breast-feeding is closely related to the nutrition supply to babies, rather than the improvement of breast-feeding, the 12 hours after the culture in which Streptococcus mutans activities started was considered. Conclusions : In case of breast-feeding at night, it is necessary to remove the dental plaque in the mouth, before 12 hours has passed. Especially, using toothbrush and toothpaste to decrease the occurrence of dental caries, after the eruption of teeth, is recommended for oral administration.

• 한국산학기술학회논문지
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• 제13권5호
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• pp.1969-1975
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• 2012

대형 상용 차량에 사용되는 에어 브레이크 시스템은 제동시 상대적으로 응답 시간이 길고 압력 손실이 크게 발생한다. 제동 시간은 파이프 시스템의 적절한 설계에 의해서 최소화 시킬 수 있다. 제동 시간은 시스템 압력의 증가, 에어 라인의 감소 및 재질의 변화에 대해 감소시킬 수 있다. 본 연구에서는 상용 트럭에 대한 리그를 구성하여 에어 브레이크의 특성에 대해서 고찰하였다. 해석 프로그램에 대한 신뢰성을 확보하기 위하여 실험 값과 비교하였고, 브레이크 시스템에 영향을 미치는 시스템 압력, 파이프의 재질 및 직경, 탱크와 챔버에서 압력에 대한 온도 영향을 검토하였다.

• 한국구조물진단유지관리공학회 논문집
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• 제6권3호
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• pp.193-199
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• 2002

콘크리트 구조물에 발생하는 구조적인 균열은 재하하중에 의하여 콘크리트가 저항할 수 있는 인장강도보다 더 큰 인장강도가 가해졌을 때 콘크리트의 인장영역에서 발생하며, 이는 구조물의 노후화 또는 재하하중에 대한 저항능력이 감소되었음을 의미한다. 그러므로 콘크리트에 발생한 구조적 균열은 구조물에 치명적인 손상을 유발시킬 수 있으며, 구조물의 안전성 확보와 효과적인 유지관리를 위해서는 이를 검출하는 기법에 대한 연구가 반드시 필요한 실정이다. 본 연구에서는 토목계측 분야에서 가장 널리 활용되고 있는 변형률 센서를 철근콘크리트 보에 부착하여 보의 인장부와 압축부의 변형률을 측정하는 실내실험을 수행하였으며, 하중 재하에 따른 변형률의 변화, 측정부위의 탄성계수 변화, 그리고 중립축의 변화 등을 비교 분석하였다. 분석 결과로부터, 측정된 변형률을 이용하여 중립축의 변화 추이를 추정하므로써 가장 효과적으로 균열을 검출할 수 있는 알고리즘을 제시하였다.

• 대한공간정보학회지
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• 제17권4호
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• pp.95-103
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• 2009

전세계적으로 다양한 관측 센서 및 자료처리 기술개발을 통하여 현실 세계에 대한 3차원 공간정보 구축에 관한 관심이 높아지고 있으며, 사생활 침해 논란에도 불구하고 도시지역 곳곳에 설치된 CCTV가 교통관리나 범죄 예방 및 재난 모니터링을 위한 핵심 관측장비로서 활용되고 있다. 도시지역의 안전 확보와 각종 재난 예방을 위해 기구축된 3차원 공간정보에 CCTV 영상이나 비디오 자료를 연계시켜 유사시 발생한 상황을 실시간적으로 인터렉티브하게 파악하고 모니터링할 수 있는 감시 시스템의 필요성이 제기되고 있다. 따라서, 본 연구에서는 웹 가시화의 국제표준인 X3D를 기반으로 3차원 공간정보와 비디오 융합을 통하여 인터넷 상에서 실시간으로 인터렉티브하게 가시화할 수 있는 프로토타입 시스템을 개발하여 그 활용가능성을 제시하고자 하였다.

• Journal of Biosystems Engineering
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• 제29권6호
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• pp.501-507
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• 2004

Fruits we subjected to complex dynamic stresses in the transportation environment. During a long journey from the production area to markets, there is always some degree of vibration present. Vibration inputs are transmitted from the vehicle through the packaging to the fruit. Inside, these cause sustained bouncing of fruits against each other and container wall. These steady state vibration input may cause serious fruit injury, and this damage is particularly severe whenever the fruit inside the package is free to bounce, and is vibrated at its resonant frequency. The determination of the resonant frequencies of the fruit may help the packaging designer to determine the proper packaging system providing adequate protection for the fruit, and to understand the complex interaction between the components of fruit when they relate to expected transportation vibration inputs. The vibration characteristics of the pears in corrugated fiberboard container in transit were analyzed using FEM (finite element method) modeling, and the FEM modeling approach was first validated by comparing the results obtained from simulation and experiment for the pear in the frequency range 3 to 150 Hz and acceleration level of 0.25 G-rms and it was found that between simulated and measured frequencies of the pears have a relatively good agreement. It was observed that the fruit and vegetables in corrugated fiberboard container could be analyzed by finite element method. As the elastic modulus of the cushion materials of corrugated fiberboard pad and tray cup decreased, the first frequencies of upper and lower pears increased and the peak acceleration decreased.

• 에너지공학
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• 제24권4호
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• pp.18-23
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• 2015

인화점은 인화성에 따라 가연성 액체들을 분류하기 위해 사용된다. 인화점은 인화성 액체를 안전하게 저장, 취급 수송하기 위한 중요한 정보이다. Tag 개방식 장치를 이용하여 두 개의 이성분계 혼합물($CCl_4+o-xylene$ and $CCl_4+p-xylene$)의 인화점을 측정하였다. 또한 라울의 법칙, UNIQUAC 식, 경험식을 이용하여 인화점을 계산하여 그 값을 측정치와 비교하였다. 이 중 경험식에 의한 인화점 계산치가 가장 측정치를 잘 모사하였다.