• Toxicological Research
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• 제27권3호
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• pp.181-184
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• 2011

Screening of estrogenic activity on dichloro diphenyl trichloroethane (DDT), dichloro diphenyl dichloro ethylene (DDE), dieldrin, heptachlor, aldrin, chlordane, lindane, polybrominated diphenyl ethers (PBDE) and parabens was compared using Organization for Economic Cooperation and Development (OECD) test guideline 455 (TG455). The estrogenic activity of DDT was 58,000-fold ($PC_{50}$, $1.67{\times}10^{-6}$ M) less than $17{\beta}$-estradiol($E_2$) ($PC_{50}$, $2.88{\times}10^{-11}$ M) but DDE, dieldrin, heptachlor, aldrin, chlordane, lindane and PBDE did not show any estrogenic activity in this assay system. In the case of paraben compounds, the rank of relative transcriptional activation (logRTA) was butyl paraben -1.63752 ($PC_{50}$, $1.25{\times}10^{-7}$ M) > isobutyl paraben -2.34008 ($PC_{50}$, $6.3{\times}10^{-7}$ M) > ethyl paraben -2.64016 ($PC_{50}$, $1.26{\times}10^{-6}$ M) > isopropyl paraben -2.73993 ($PC_{50}$, $1.58{\times}10^{-6}$ M) > propyl paraben -2.84164 ($PC_{50}$, $2.0{\times}10^{-6}$ M). Our data suggest that OECD test guideline TG455 may be useful as a screening tool for potential endocrine disruptors.

• 자동차안전학회지
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• 제12권3호
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• pp.43-51
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• 2020

Currently, the second level of the six stages of self-driving technology, as defined by SAE, is commercialized, and the third level is preparing for commercialization. The purpose of ACC is to be evaluated as a system useful for preventing and preventing accidents by minimizing driver fatigue through longitudinal speed control and relative distance control of the vehicle. In this regard, for the study of safety assessment methods in the practical environment of ACC. Distance measurement method using monocular camera and data acquisition equipment such as DGPS are utilized. Based on the evaluation scenario considering the domestic road environment proposed by the preceding study, the relative distance obtained from equipment such as DPGS and the relative distance using a monocular camera in the actual test is verified by comparing and analyzing the safety assessment. The comparison by scenario results showed a minimum error rate of 3.83% in Scenario 1 and a maximum of 14.61% in Scenario 6. The cause of the maximum error is that the lane recognition is not accurate in the camera image and irregular operation conditions such as rushing in or exiting the surrounding area from the walkway. It is expected that safety evaluation using a monocular camera will be possible for other ADAS systems in the future.

• 에너지공학
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• 제17권4호
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• pp.212-217
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• 2008

본 연구는 이동식 부탄연소기에 사용되는 1회용 부탄캔의 변형 및 폭발을 방지하기 위하여, 캔에 안전밸브를 장착한 폭발방지 부탄캔에 대한 사용 중 안전성을 평가하였다. 실제 사용환경에서 설계압력의 오차 범위 내에서 안전밸브가 작동하는지, 안전밸브의 분출유량은 캔의 변형 및 폭발을 방지하기에 적정하게 설계되었는지, 그리고 안전밸브 작동으로 인하여 가스가 누출되었을 때 주변의 점화원에 의한 화재 및 폭발의 위험성 등을 평가하였다. 본 연구를 통해 개발제품이 외부열원에 의한 부탄캔의 내압상승을 방지하여 캔의 폭발을 방지하는 것으로 평가되었다.

• 자동차안전학회지
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• 제10권2호
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• pp.20-28
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• 2018

Currently, sharp increase of car is on the rise as a serious social problem due to loss of lives from car accident and environmental pollution. There is a study on ITS (Intelligent Transportation System) to seek coping measures. As for the commercialization of ITS, we aim for occupancy of world market through ASV (Advanced Safety Vehicle) related system development and international standardization. However, the domestic environment is very insufficient. Core factor technologies of ITS are Adaptive Cruise Control, Lane Keeping Assist System, Forward Collision Warning System, AEB (Autonomous Emergency Braking) system etc. These technologies are applied to cars to support driving of a driver. AEB system is stop the car automatically based on the result decided by the relative speed and distance with obstacle detected through sensor attached on car rather than depending on the driver. The purpose of AEB system is to measure the distance and speed of car and to prevent accident. Thus, AEB will be a system useful for prevention of accident by decreasing car accident along with the development of automobile technology. This study suggests a scenario to suggest a test evaluation method that accords with domestic environment and active response of international standard regarding the test evaluation method of AEB. Also, by setting the goal with function for distance, it suggests theoretic model according to the result. And the study aims to verify the theoretic evaluation standard per proposed scenario using car which is installed with AEB device through field car driving test on test road. It will be useful to utilize the suggested scenario and theoretical model when conducting AEB test evaluation.

• 한국가스학회지
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• 제23권5호
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• pp.8-14
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• 2019

국내 도시가스 보급률은 크게 성장했지만, 국내 가스계량기 계량·안전점검·요금 분야는 아직 서비스 초기방식에서 벗어나지 못하고 있다. 스마트가스미터에 관한 개발과 연구가 활발히 이루어지고 있지만 스마트가스미터의 도입에는 신뢰성과 안전성을 검증할 수 있는 합리적인 성능평가 방안과 기준이 필요하다. 본 논문은 스마트가스미터의 성능을 시험하기 위한 성능시험 시작품을 제작하고 시작품의 실증 운용을 통해 성능평가 방안을 최적화하여 국내에 스마트가스미터가 원활하게 확대/보급될 수 있도록 하는 것을 목적으로 한다.

• 한국안전학회지
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• 제33권2호
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• pp.152-157
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• 2018

The degradation and damage of the components for ballasted track could be caused a serious problem for railway safety. Therefore, the integrity evaluation of ballasted track condition is important to ensure and predict that the track safety and track maintenance. Various track components such as rail pad, ballast, sleeper, and rail that are widely used in Republic of Korea and represent a range of physical properties have been selected for this research. In this study, the experimental modal analysis was performed by the non-destructive testing. Modal test results were obtained from the field test and used to assess the condition of the track components. From the field test, the system of ballasted track was found to be simplified as a two-degree-of-freedom(2DOF) dynamic system. The condition of track component was found to directly affect the dynamic response of ballasted tracks. As the results, the dynamic properties of the track component was depend on the track condition and was distributed more roughly and over a wider range than its initial design values. Further, the methodology presented in this study is possible to determine experimentally the fundamental track parameters which are required in the numerical analysis, and also are useful for the safety assessment of track condition.

• 한국안전학회지
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• 제30권1호
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• pp.52-59
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• 2015

The aim of the paper is to introduce the statistical definition of the specified compressive strength of the concrete to be used for safety evaluation of the existing structure in domestic practice and to present the practical method to obtain the specified strength by utilizing the non-destructive test data as well as the limited number of core test data. The statistical definition of the specified compressive strength of concrete in the design codes is reviewed and the consistent formulations to statistically estimate the specified strength for assessment are described. In order to prevent estimating an unrealistically small value of the specified strength due to limited number of data, it is proposed that the information from the non-destructive test data is combined to that of the minimum core test data. The the sample mean, standard deviation and total number of concrete test are obtained from combined test data. The proposed procedures are applied to an example test data composed of the artificial numerical values and the actual evaluation data collected from the bridge assessment reports. The calculation results show that the proposed statistical estimation procedures yield reasonable values of the specified strength for assessment by applying the non-destructive test data in addition to the limited number of core test data.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2009년도 춘계학술대회 논문집
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• pp.341-344
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• 2009

In this paper, protective function evaluation was conducted to determine the performance and safety of a power conditioning system(PCS) for 1kW residential fuel cell system. It is essential to have a power quality, grid-connection and safety of PCS. Even though it is under 500ms by KGS-A410 standard, it is shown a rapid response time of 25ms from input under-voltage test. In terms of output over/under-voltage test, it is shown 29.15 and 79.4ms. Especially using anti-islanding test, it is shown all times under 100ms for combination cases of real and reactive power. We confirmed a rapid response characteristics and safety of PCS. The results of this evaluation are being used to develop a new test protocols of PCS.

• 한국식품위생안전성학회지
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• 제24권4호
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• pp.312-317
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• 2009

세균포자는 살균소독제에 대해 영양세포보다 수백~수천배이상 저항성을 가지고 있기 때문에 과산화수소 및 과산화초산을 원료로 하는 아포살균용 살균소독제는 Escherichia coli 및 Staphylococcus aureus의 감소율을 측정하는 현행 살균소독제 유효성 평가방법을 적용하기 어렵다. 따라서, 아포살균용 살균속독제의 유효성 평가를 위해 Bacillus subtilis ATCC 6633 포자를 표준균주로 하여 아포살균용 살균소독제를 처리했을 때 초기포자수를 $10^3$이상 감소시키는지를 측정하는 정량적 표준시험방법을 확립하였다. 확립된 시험법은 아포살균력을 측정하는 국가표준시험법으로서 아포살균용 살균소독제의 유효성 평가에 적합하였다.

• Toxicological Research
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• 제34권3호
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• pp.191-197
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• 2018

In 2015, a candidate for the second national reference standard (NRS) of Gloydius snake venom was produced to replace the first NRS of Gloydius snake venom. In the present study, the potencies of the candidate were determined by a collaborative study, and the qualification of the candidate was estimated. The potencies of the candidate were determined by measuring the murine lethal titers and lapine hemorrhagic titers of venom against the regional working reference standard (RWRS) for antivenom using the methods described in the previous report for the first NRS of Gloydius snake venom. Three Korean facilities contributed data from a total of 30 independent assays. Subsequently, two foreign national control research laboratories contributed to this collaborative study. The results were calculated using the Reed-Muench method for lethality and determined using a mixed-effects model for hemorrhage. The general common potencies of the lethal and hemorrhagic titers were obtained from the results of the 30 tests performed at three Korean facilities. The results are expressed in micrograms for 1 test dose (TD) with a 95% confidence interval as follows: a lethal titer of $90.13{\mu}g/TD$ (95% confidence interval = $87.39{\sim}92.86{\mu}g$) and a hemorrhagic titer of $10.80{\mu}g/TD$ (95% confidence interval = $10.46{\sim}11.14{\mu}g$). In addition, the candidate preparation showed good quality evaluation according to the results of the quality estimation of the candidate and is judged to be suitable to serve as the Korean NRS for snake venom. In conclusion, the second NRS of Gloydius snake venom was established in this study and will be used for national quality control, including a national lot release test of Korean antivenom products.