• Title/Summary/Keyword: Safety evaluation test

Search Result 1,731, Processing Time 0.036 seconds

Evaluation on the Safety of ${\gamma}$-Irradiated Angelica gigas Nakai: Stability of Active Components and Safety in Genotoxicity Test (감마선 조사 당귀(Angelica gigas Nakai)의 유효성분 안정성 및 유전독성학적 안전성 연구)

  • 조성기;유영법
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.29 no.2
    • /
    • pp.300-306
    • /
    • 2000
  • In the present studies, we assessed the stability of active components and toxicological safety of irradiated Angelica gigas Nakai(Danggui). In order to confirm the stability of active components in the ${\gamma}$-irradiated roots of Danggui, the quantitative analysis of decursin and decursinol angelate of ${\gamma}$-irradiated sample was carried out by high performance liquid chromatographic (HPLC) methods using reverse phase columns and normal phase columns. From the root of Danggui, decursin and decursinol angelate were isolated by a silica gel column chromatography(toluene : ether (1 : 1), Hexane : EtOAc(15 : 1)). And then the structures were confirmed in the 1H and 13C-NMR analysis. The HPLC chromatograms of decursin and decursinol angelate in ${\gamma}$-irradiated Danggui were similar with those of non-irradiated sample. In the examination of in vitro genotoxicity of the water extract from ${\gamma}$-irradiated Danggui using Salmonella reversion assay(Ames test) and micronucleus test in Chinese hamster ovary (CHO) cells, mutagenicity was not exhibited in the two assays with or without metabolic activation. These resutls suggest that active components in the ${\gamma}$-irradiated Danggui should be stable and that the safety of ${\gamma}$-irradiated Danggui could be revealed in further test in vivo.

  • PDF

Measurement & analysis of derailment coefficient for korean tilting vehicle (한국형 틸팅차량의 탈선계수 측정 및 분석)

  • Ham, Young-Sam;Seo, Jung-Won;Lee, Dong-Hyong;Kwon, Seok-Jin;Kim, Jae-Chul;Lee, Chan-Woo
    • Proceedings of the KSR Conference
    • /
    • 2008.11b
    • /
    • pp.1628-1633
    • /
    • 2008
  • Safety of railroad is result of reliability which is received from test & evaluation of system. Railroad system is consisted of various sub system such as vehicle, supply of electric power, signal, communication, rail track construction, operation. To secure safety of railroad, evaluation about parts, assembly, sub system, whole system etc.. that compose railroad is essential. In this paper, I wish to describe for results that analyze korean tilting vehicle's derailment coefficient developed by national research achievement. Result that evaluation korean tilting vehicle's running safety, verified that secure even if speed-up 30 km/h than operating speed of present in curved line.

  • PDF

Evaluation criteria for freezing and thawing of tunnel concrete lining according to theoretical and experimental analysis

  • Moon, Joon-Shik;An, Jai-Wook;Kim, Hong-Kyoon;Lee, Jong-Gun;Lattner, Tim
    • Geomechanics and Engineering
    • /
    • v.29 no.3
    • /
    • pp.349-357
    • /
    • 2022
  • Abnormal climate events are occurring frequently around the world. In particular, cold waves and heavy snow lead to damage and deterioration of facilities, which can cause loss of life or property damage, such as shortening the lifespan of facilities. Therefore, it is very important to prepare an appropriate maintenance system and to establish a strategy to cope with abnormal weather conditions. In this study, laboratory freezing experiments were performed to analyze the freeze-thaw characteristics affecting the tunnel concrete lining, and heat flow analysis was carried out based on the test results. Based on these experimental and theoretical analysis results, quantitative freeze-thaw evaluation criteria for tunnel concrete linings were proposed.

Development of Safety Evaluation Scenarios for Autonomous Vehicle Tests Using 5-Layer Format(Case of the Community Road) (5-레이어 포맷을 이용한 자율주행자동차 실험 시나리오 개발(커뮤니티부 도로를 중심으로))

  • Park, Sangmin;So, Jaehyun(Jason);Ko, Hangeom;Jeong, Harim;Yun, Ilsoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.18 no.2
    • /
    • pp.114-128
    • /
    • 2019
  • Recently, the interest in the safety of autonomous vehicles has globally been increasing. Also, there is controversy over the reliability and safety about autonomous vehicle. In Korea, the K-City which is a test-bed for testing autonomous vehicles has been constructing. There is a need for test scenarios for autonomous vehicle test in terms of safety. The purpose of this study is to develop the evaluation scenario for autonomous vehicle at community roads in K-City by using crash data collected by the Korea National Police Agency and a text-mining technique. As a result, 24 scenarios were developed in order to test autonomous vehicle in community roads. Finally, the logical and concrete scenario forms were derived based on the Pegasus 5-layer format.

Evaluation of The Seepage Behavior for Reinforced Embankment (보강제체사면의 침투거동평가)

  • 신방웅;안병철
    • Journal of the Korean Society of Safety
    • /
    • v.15 no.1
    • /
    • pp.146-152
    • /
    • 2000
  • To estimate the behavior of reinforced and unreinforced embankment constructed on a impermeable foundation ground, a laboratory model test was performed for two types of soils and water level increasing velocity of a flood period. The experiment models were constructed with slopes of water level is 1.25cm/min, 2.5cm/min each. From model test results, as the slope of reinforced and unreinforced embankment was the slower, the more seepage line rised. In the unreinforced embankment, the rising velocity of water level was the faster, the larger the embankment failure was. And the reinforced embankment with geotextile was the more safe than the unreinforced embankment for seepage force.

  • PDF

The Cognition Level on Patient Safety and Safe Nursing Activities According to Nurse-patient Ratios (간호관리료 등급별 환자안전 및 안전간호활동 인식 비교)

  • Nam, Mun Hee;Choi, Sook Hee
    • Journal of Korean Clinical Nursing Research
    • /
    • v.17 no.2
    • /
    • pp.138-149
    • /
    • 2011
  • Purpose: The objective of this research was to explore levels of patient safety and safe nursing activities depending on the level of nurse staffing, in order to provide effective management of nurse personnel. Methods: The research was conducted with 455 nurses from eight hospitals in B city. Data were collected according to the level of nurse personnel from second (nurse vs. patient ratio of 2.0-2.5) to fifth (ratio of 3.5-4.0) rank. The survey tools were, 'Questionnaire on Patient Safety, a Hospital Survey on Patient Safety Culture developed by AHRQ (2007), and 'Questionnaire on Patient Safety Nursing Act, in which the questions were selected from nursing-related items (Medication 6 & Safety Nursing Assurance Act 4) in the Safety Evaluation developed by Evaluation Institute of Medical Institution. Data were analyzed with SPSS PC 12.0 program using descriptive statistics, $x^2$ test, ANCOVA and $Scheff{\grave{e}}$. Results: The nurses' overall cognition level on patient safety and safe nursing activities showed that nurses who are in the second and third rank had higher scores than those in lower ranks. Conclusion: The results of this study indicate that hospitals need a higher ratio level for nurse personnel in order to assure patient safety and safe nursing activities.

A Study on the Test and Evaluation Methodology for the Precise Encountering Scenario between Ammunitions (탄약 간 정밀교전을 위한 시험평가기법 연구)

  • Ha, Jongsoo;Park, Youngsik;Lee, Hanjin;Kim, Yongjae;Kwak, Yoon;Park, Minkyu
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.21 no.6
    • /
    • pp.776-783
    • /
    • 2018
  • This paper proposes an improved test and evaluation methodology to be conducted for a in-flight threat-countermeasure encounter scenario. Although the conventional test method adopted in the precedent researches allows high precision and safety, such full-scale method is practically not appropriate to apply to small-scale test rounds for evaluating the subparts of the ammunition. To address this problem, this study suggests a readily-applicable, small-scale test and evaluation method of the subpart of the ammunition in firing test. In the threat-countermeasure encounter scenario, the results of several tests demonstrate that the proposed technique does not deteriorate the precision when the engagement point should be adjusted.

Concentration of Polycyclic Aromatic Hydrocarbons in Cereals, Pulses, Potatoes, and their Products (곡류, 두류, 서류 및 그 가공품 중 다환 방향족 탄화수소 (polycyclic aromatic hydrocarbons) 화합물 함량)

  • Kim, Hee-Yun;Chung, So-Young;Sho, Yo-Sub;Park, Seong-Soo;Lee, Eun-Ju;Suh, Jung-Hyuk;Lee, Yun-Dong;Choi, Woo-Jeong;Kim, Jung-Soo;Eom, Ji-Yoon;Park, Hui-Og;Jin, Myeong-Sig;Kim, Dong-Sul;Ha, Sang-Chul;Lee, Jong-Ok
    • Korean Journal of Food Science and Technology
    • /
    • v.37 no.4
    • /
    • pp.537-541
    • /
    • 2005
  • Estimation of concentrations of PAHs [benzo(a)anthracene, chrysene, benzo(b)fluoranthene, benzo(k)fluoranthene, benzo(a)pyrene, dibenzo(a,h)anthracene, benzo(g,h,i)perylene, indeno(1,2,3-c,d)pyrene] in cereals, pulses, potatoes, and their products available in Korean markets gave mean levels of 0.13, 0.08, 0.06, 0.03, 0.08, 0.15, 0.45, and $0.14{\mu}g/kg$, respectively, with recoveries between 82.6-106.6%. Methodology involved saponification and extraction with n-hexane, purification on Sep-Pak Florisil cartridges, and high performance liquid chromatography using a fluorescence detector.

Safety Evaluation of Bogie Frame for Tilting Railway Vehicles by Fatigue and Nondestructive Tests (피로시험 및 비파괴 검사를 통한 틸팅열차용 주행장치 프레임의 안전성 평가)

  • Kim Jung-Seok;Kim Nam-Po
    • Journal of the Korean Society for Railway
    • /
    • v.8 no.5
    • /
    • pp.419-424
    • /
    • 2005
  • This paper has performed fatigue and nondestructive test of bogie frame for Korean tilting train. Before the fatigue test, static tests were carried out. From the test, the structural safety was investigated using Goodman diagram. After the static test, the fatigue test were conducted under tilting load conditions. The fatigue test was conducted for $10{\times}10^6$ cycles. During the fatigue test, the nondestructive tests using magnetic particle and liquid penetrant were performed at $6{\times}10^6$ cycle and $10{\times}10^6$cycle. From the crack detection tests, it was known that there was no fatigue crack in the bogie frame.

A study on structural integrity and dynamic characteristic of inertial load test equipment for performance test of railway vehicle propulsion control system (철도차량 추진제어장치 성능시험을 위한 관성부하 시험설비의 구조안전성 및 동특성 평가 연구)

  • Jang, Hyung-Jin;Shin, Kwang-Bok;Lee, Sang-Hoon;Lee, Dae-Bong
    • Proceedings of the KSR Conference
    • /
    • 2010.06a
    • /
    • pp.1389-1394
    • /
    • 2010
  • This paper describes the evaluation of structural integrity and dynamic characteristic of inertial load test equipments for performance test of railway vehicle propulsion control system. The propulsion control system of railway vehicle has to be confirmed of safety and reliability prior to it's application. Therefore, inertial load test equipments were designed through theoretical equation for performance test of propulsion control system. The structural analysis of inertial load test equipments was conducted using Ansys v11.0 and it's dynamic characteristic was evaluated the designed using Adams. The results showed that the structural integrity of inertial load test equipment was satisfied with a safety factor of 10.2. Also, the structural stability was proved by maximum dynamic displacement of 0.82mm.

  • PDF