• Title/Summary/Keyword: Safety evaluation test

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Toxicity Evaluation of a Non-Pain Pharmacopuncture Extract Using a Bacterial Reverse Mutation Test

  • Ji Hye Hwang;Chul Jung
    • Journal of Pharmacopuncture
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    • v.27 no.2
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    • pp.154-161
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    • 2024
  • Objectives: The objective of this study was to assess the genotoxicity of a no-pain pharmacopuncture (NPP) extract developed in 2022 using a bacterial reverse mutation assay, aiming to further substantiate the safety profile of NPP. Methods: The genotoxicity evaluation involved a bacterial reverse mutation assay to assess the mutagenic potential of NPP extracts with and without metabolic activation. Histidine-requiring Salmonella typhimurium strains (TA98, TA100, TA1535, and TA1537) and tryptophan-requiring Escherichia coli strains (WP2uvrA) were used in the assay. Results: The NPP extract did not induce a revertant colony count exceeding two times that of the negative control at any dose level in any of the tested strains, both with and without metabolic activation. Additionally, no growth inhibition or precipitation was observed in the presence of NPP. Conclusion: Based on the findings, it can be concluded that the NPP extract exhibited no mutagenic potential in the in vitro genotoxicity tests conducted.

Useful Lifetime Evaluation of Rubber Component for Elevator Cabin (승강기용 방진고무부품 특성 및 사용수명 평가)

  • Woo, Chang-Su;Park, Hyun-Sung
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.576-580
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    • 2008
  • Rubber material properties and useful life evaluation are very important in design procedure to assure the safety and reliability of the rubber components. In this paper, the evaluation of characteristics and useful life prediction of rubber component for elevator cabin were experimentally investigated. The material test and accelerated heat-aging test were carried. Rubber material constants were obtained by curve fittings of simple tension, pure shear and bi-axial tension test data. Heat aging test results changes as the threshold are used for assessment of the useful life and time to threshold value were plotted against reciprocal of absolute temperature to give the Arrhenius plot. By using the rubber material and component test several useful life prediction equations for rubber component were proposed. Predicted useful life of rubber component for elevator cabin agreed fairly with the experimental lives.

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The Evaluation of Reliability for the High Pressure Hydrogen Storage System of Fuel Cell Vehicle (연료전지자동차의 고압수소저장시스템 신뢰성 평가)

  • Jang, Gyu-Jin;Choi, Young-Min;Ahn, Byung-Ki;Lim, Tae-Won
    • Journal of Hydrogen and New Energy
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    • v.19 no.4
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    • pp.266-275
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    • 2008
  • The performance improvement of each part for durability, safety and cost of high pressure storage system for fuel cell vehicle has been focused so far. However, for the mass production of fuel cell vehicle, it is necessary to evaluate durability and safety in system module and vehicle level. The test procedure to evaluate vibration and collision safety of high pressure hydrogen storage system for the fuel cell vehicle is established and its reliability is verified.

Evaluation of the Environmental Qualification for Non-metallic Parts (비금속부품 내환경검증 수명평가)

  • Bhang, Keug-Jin;Hong, Jun-Hee
    • Journal of Power System Engineering
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    • v.20 no.5
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    • pp.52-59
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    • 2016
  • Environmental Qualification has been almost developed except those of Non-Material Sub-components for valves and pumps though the time has only passed about 10years since EQ test launch of Korea. However EQ test has been performed by a few of engineers under the conditions that experience of EQ test is insufficient and EQ system is not developed completely. In recent years, Strengthen Nuclear Safety Regulation is being done Strictly Nuclear safety components Verification Procedure for Non-Material Sub-components, but the reports contain only performance test results, not Enviro nmental test methods relating to real Aging Degradation. In this Study, there were developed to performance systematically research to acquire EQ technology for five specimens of the Non-Material Sub-components in the Nuclear Power Plant.

Strength Evaluation of A Failed A53B Carbon Steel Pipe with Small Punch Test and Finite Element Analysis (소형펀치시험과 유한요소해석을 이용한 A53B 탄소강 파손 배관의 강도 평가)

  • Lee, Joon-Won;Kim, Maan-Won;Shin, Kyu-In;Park, Jai-Hak
    • Journal of the Korean Society of Safety
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    • v.23 no.1
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    • pp.1-11
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    • 2008
  • In this study, small punch test and tensile test were performed with specimens directly machined from an ASTM A53 grade B carbon steel pipe at which an explosion accident was occurred in the Heavy Oil Unit. Main damage mechanism of the pipe was known as a high temperature hydrogen attack(HTHA). Effects of HTHA on the mechanical strength change of the A53B steel were studied in detail. Small punch test results have showed that maximum reaction forces, SP energy and ductility were decreased at hydrogen attacked part of the pipe compared with sound part of the pipe. Yield strength and tensile ultimate strength were calculated with the obtained small punch test curve results using different methods and compared the estimation methods. Small punch test simulation has been also performed with the finite element method and then mechanical strength, equivalent strain and fracture toughness were calculated with the obtained numerical analysis results. It was shown that the fracture toughness data calculated from small punch equivalent energy obtained by the finite element analysis for SP test was very low at the hydrogen attacked part.

The Fundamental Study on the Development of Leisure Boat's Drop Test Management System based on ISO 12215-5 (ISO 12215-5에 기반 한 레저선박 낙하시험 평가시스템 개발을 위한 기초연구)

  • Kang, Nam-Seon;Park, Chung-Hwan
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.18 no.4
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    • pp.365-370
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    • 2012
  • International Organization for Standardization has recently published ISO 12215-5 which is the small craft-hull construction and scantling. According to ISO 12215-5 AnnexB, the scantling determination can be accomplished by drop test for craft with a length $L_H$ of 2.5m up to 6m and single-skin construction. The current method, however, of visual test has the issue where it is difficult to make an objective evaluation of ship body strength. In this study, in order to develop an evaluation system that can make a quantitative evaluation of the drop test of leisure boats, the domestic/foreign regulations on drop test of leisure boats are analyzed and the drop test evaluation system is designed, and the system applicability is reviewed through 5-meter level aluminum ship, and the issues incurred by the state of the ship and the posture while dropping were checked.

Characteristic Analysis for Weight Values of Evaluation Items by Traffic Safety Project Type (교통안전사업 유형별 평가항목의 가중치 특성분석)

  • Lee, Heewon;Lee, Jisun
    • International Journal of Highway Engineering
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    • v.20 no.1
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    • pp.147-156
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    • 2018
  • PURPOSES : The purpose of this study is to analyze the characteristics of the weight values of evaluation items by traffic safety project type. METHODS : In general, a large-scale investment in projects such as the traffic safety project requires economic analyses to be performed in advance. However, there is an argument for considering special characteristics of the traffic safety project. Therefore, this study conducted characteristic analysis of the weight values of evaluation items. The analysis consisted of two steps. The first step was hypothesis verification using analysis of variance (ANOVA). In this process, the authors examined whether the weight of evaluation items is the same regardless of the traffic safety project type. Based on the first step's results, the authors proceeded to the second step. The objective of this step was to analyze how different the weight values are by traffic safety project type using an analytic hierarchy process. RESULTS : According to the ANOVA test results, the benefit to cost ratios have different weight values based on traffic safety project type at the 0.01 significance level. The policy evaluation items, such as the plans connection, resident opinion, and regional equity, also showed the same results except that the result for the related plans connection was statistically significant at the 0.05 level. Based on the first step's result, the AHP analysis in the second step showed that the traffic safety projects for vulnerable users and pedestrians have very low weight values in economic evaluation factors compared with other safety project types. The weight values for vulnerable users and pedestrians were 0.29 and 0.26, respectively, in economic evaluation items. On the other hand, the weight values for other safety project types were around 0.6. Among the policy evaluation items, resident opinion showed a higher weight value than other factors, such as connection and regional equity items. CONCLUSIONS : The social and economic impact of a traffic safety project varies by project type and project characteristics. Although the economic approach is overarching and a reasonable methodology is applied for large-scale projects, it should be noted that the safety issue, especially for transportation of vulnerable uses, requires a non-economical approach. Based on the analysis results, this study suggests that the priority of the projects should be determined by separating them into independent assessment groups depending on their characteristics.

Safety Evaluation Based on Structural Analysis of Cylinder Valves for Fuel Cell Vehicles (구조해석을 이용한 수소 연료전지 자동차 압력용기 밸브의 안전성 평가)

  • Lee, Hyo Ryeol;Ahn, Jung Hwan;Shin, Jin Oh;Kim, Hwa Young
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.25 no.3
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    • pp.189-197
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    • 2016
  • Green vehicles include electric vehicles, natural gas vehicles, and fuel cell vehicles (FCVs). In FCVs, pressure vessels have cylinder valves to control hydrogen flow. These valves should be of high quality in terms of safety because hydrogen is stored at ultra-high pressure in pressure vessels. Hence, safety evaluation of these valves is necessary to secure the safety of the FCV. A structural analysis of the cylinder valve was conducted in this study by using a commercial finite element analysis code. The results showed that the safety factor of valve component ranged 1.06-186.44. After categorizing, the stress components at critical points of the cylinder valve parts were evaluated using the corresponding allowable design criteria in the ASME code. The pressurization cycle test was performed as per the regulation to evaluate the safety of the valve.

Flow capacity test of spring load safety relief valves used in LNG (LNG 선박용 spring load 안전방출밸브의 유량 성능시험)

  • Park, Kyung-Am;Lee, Saeng-Hee;Kim, Keng-Kuen;Goh, Jang-Hoon
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.95-98
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    • 2006
  • Many LNG ships will be constructed in Korea and the demand of safety valves is increasing. The most important performance of the developed safety relief valves for LNG ship is flow capacity. Flow capacity tests for 8 sizes of developed safety valves were conducted in the high pressure gas flow standard system in KRISS. The initial spring force adjustment was important for setting pressure of the safety valve. The procedure of data reduction and evaluation of the safety valve performance are suggested. This procedure was approved by French Bureau Veritas and Lloyd's Register.

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A Study of the Construction of Comprehensive Flight Testing Infrastructure to Increase Aviation Safety (항공안전 증진을 위한 비행종합시험 인프라 구축 방안 연구)

  • Kim, Seung-Han;Kim, Gyou-Beom;Yim, Jae-Hyun
    • Journal of Convergence for Information Technology
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    • v.10 no.9
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    • pp.147-153
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    • 2020
  • As demand for drone test flight is rapidly increasing, it is difficult for Goheung Aviation Center alone to meet the test flight demand. Newly developed drones or modified existing aircraft carry potential flight risks due to unpredictable flight performance or poor pilot skill when performing test flights outside the test site. Therefore, it is necessary to ensure sufficient test flight space for the safety verification of manned and unmanned aircraft. Therefore, this study analyzed the status of domestic flight test site and chapter 5 of ICAO DOC 9184-AN / 902 Part 1 (Airport Planning Manual). And to build a comprehensive flight test infrastructure, the methodology for preliminary evaluation of candidate sites for flight test sites and a method for evaluating infrastructure test sites was presented.