• Journal of Wetlands Research
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• v.16 no.2
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• pp.235-243
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• 2014

According to the "Safety Evaluation Detailed Instructions (Dam)", precise safety inspection is carried out for dams that exceed a certain scale. However, as the Hydrological Safety Evaluation from various evaluation standards is designed to evaluate the safety of existing dams considering PMF, the evaluation is much less applicable for most agricultural reservoirs. Therefore, the Hydrological Safety Guidelines for agricultural reservoirs are expected to be re-evaluated considering the diverse risk factors with the coefficient model and AHP in this study. The coefficient model has been developed by selecting the hydrological safety superordinate subordinate evaluation factors to reflect diverse risk factors of agricultural reservoirs. After calculating the sum of indicators score for each evaluation factors, validation procedures were performed for the questionnaire which a panel answered. The practical coefficient has eventually been estimated for the hydrological safety evaluation considering the diverse risk factors. The conclusions acquired based on the study done are that both most agricultural reservoirs were classified as flood defense capability is insufficient and agricultural reservoirs which meet embankment-freeboard standards considering PMF was overestimated.

• Journal of the Korea Safety Management & Science
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• v.7 no.4
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• pp.165-177
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• 2005

Supply Chain Management(SCM) system is a critical investment that can affect future competitiveness and performance of a company. Selection of a right SCM system is one of the critical issues. This paper provides the characteristic factors of SCM system selection and the SCM system evaluation and selection model based on Analytic Hierarchy Process(AHP). The proposed model can systematically construct the objectives of SCM system selection to support the business goals. A empirical example demonstrates the feasibility of the proposed model and the model can help a company to make better decision-making in selecting SCM system.

• Journal of the Korea Safety Management & Science
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• v.14 no.1
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• pp.33-42
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• 2012

This paper dealt with developing conceptual model for making public policy on consumer product safety. The matters of consumer safety, public health and environmental protection are essential parts of making policy for consumer products. Moreover, policy authority should consider all measures based on consumer safety. In the process making regulations, policy authority has to have some methods to prevent errors on treating eligible persons as persons disqualified under uncertainty decision making of public policy. To recognize and ensure fairness on public policy, policy authority needs to establish basic policy making and fundamental concepts. Therefore, we developed conceptual model for consumer products safety, CPSPcon in this paper. The conceptual model is one part of SSM(Soft System Methodology) and can support specific policy target. The CPSPcon model can assist in evaluation of responses to an adapting or considering model.

• Proceedings of the Korean Nuclear Society Conference
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• 2004.10a
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• pp.523-524
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• 2004

• Genomics & Informatics
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• v.8 no.1
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• pp.50-57
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• 2010

Mercuric chloride, a model nephrotoxicant was used to elucidate time- and dose- dependent global gene expression changes associated with proximal tubular toxicity. Rat kidney cell lines NRK-52E cells were exposed for 2, 6 and 12 hours and with 3 different doses of mercuric chloride. Cell viability assay showed that mercuric chloride had toxic effects on NRK-52E cells causing 20% cell death (IC20) at $40{\mu}M$ concentration. We set this IC20 as high dose concentration and 1/5 and 1/25 concentration of LC20 were used as mid and low concentration, respectively. Analyses of microarray data revealed that 738 genes were differentially expressed (more than two-fold change and p<0.05) by low concentration of mercuric chloride at least one time point in NRK-52E cells. 317 and 2,499 genes were differentially expressed at mid and high concentration of mercuric chloride, respectively. These deregulated genes showed a primary involvement with protein trafficking (CAV2, CANX, CORO1B), detoxification (GSTs) and immunity and defense (HMOX1, NQO1). Several of these genes were previously reported to be up-regulated in proximal tubule cells treated with nephrotoxicants and might be aid in promoting the predictive biomarkers for nephrotoxicity.

• Toxicological Research
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• v.34 no.3
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• pp.191-197
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• 2018

In 2015, a candidate for the second national reference standard (NRS) of Gloydius snake venom was produced to replace the first NRS of Gloydius snake venom. In the present study, the potencies of the candidate were determined by a collaborative study, and the qualification of the candidate was estimated. The potencies of the candidate were determined by measuring the murine lethal titers and lapine hemorrhagic titers of venom against the regional working reference standard (RWRS) for antivenom using the methods described in the previous report for the first NRS of Gloydius snake venom. Three Korean facilities contributed data from a total of 30 independent assays. Subsequently, two foreign national control research laboratories contributed to this collaborative study. The results were calculated using the Reed-Muench method for lethality and determined using a mixed-effects model for hemorrhage. The general common potencies of the lethal and hemorrhagic titers were obtained from the results of the 30 tests performed at three Korean facilities. The results are expressed in micrograms for 1 test dose (TD) with a 95% confidence interval as follows: a lethal titer of $90.13{\mu}g/TD$ (95% confidence interval = $87.39{\sim}92.86{\mu}g$) and a hemorrhagic titer of $10.80{\mu}g/TD$ (95% confidence interval = $10.46{\sim}11.14{\mu}g$). In addition, the candidate preparation showed good quality evaluation according to the results of the quality estimation of the candidate and is judged to be suitable to serve as the Korean NRS for snake venom. In conclusion, the second NRS of Gloydius snake venom was established in this study and will be used for national quality control, including a national lot release test of Korean antivenom products.

• Journal of the Korean Society of Safety
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• v.16 no.3
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• pp.125-134
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• 2001

The Advanced Pressurized rater Reactor 1400(APR1400) system is advanced of the successful Korean Nuclear Power Plants(KSNP) design which meets functional needs for safety enhancement reliability improvement, and control in the human-computer monitoring system. Therefore this paper describes the scoring model in order to justify the reliability and safety in APR 1400 under uncertainty. The structure of this paper consists of the human engineering, risk safety, quality function, safety organization management factors of the qualitative factors in chapter 2, and the expectation results of the normalized scoring model in chapter 3. Finally, the proposed reliability model have provided the technical flexibility not only for functional control fields but also for accidents protection systems in APR 1400 under uncertainty.

• Journal of the Korean Institute of Gas
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• v.21 no.3
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• pp.70-76
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• 2017

Although various methods have been tried to measure the safety culture of firms, they are limited to derive the qualitative analysis results according to the subjective criteria that are not formalized according to the evaluation method. We developed a questionnaire that can be applied to a combined power plant, quantified the evaluation results using the system dynamics model based on the results, and conducted simulation through various scenarios. And to present the criteria for safety cultural policy.

• Journal of Korean Society of Disaster and Security
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• v.16 no.2
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• pp.1-13
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• 2023

As interest in urban safety has increased since COVID-19, various institutions have developed and used indicators that evaluate the safety city model. Yongsan-gu was ranked No. 1 in 2021 by Social Safety Index evaluation and was selected as the safest city in Korea. However, the Itaewon disaster in Yongsan-gu in 2022 caused many casualties. The study of indicators for evaluating cities' safety was necessary. This study aims to examine domestic and foreign safe city models and review the differences between each model and the indicators used to evaluate safe cities. As a result of collecting 11 safe city models and analyzing each evaluation index, safe city models can be classified into program-based safe city models, such as the World Health Organization's International safe community and the UN Office for Disaster Risk Reduction's International Safe city. Considering the diversification of threats to safety, it is reasonable to comprehensively consider digital security, health safety, infrastructure safety, personal safety, environmental safety, traffic safety, fire safety, crime safety, life safety, suicide, and infectious diseases when evaluating safe cities as evaluation parameters.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1993.04a
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• pp.45-52
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• 1993

Evaluation of structural stability of aged wharf structure of pier type is of great importance for both safety and rehabilitation, Series of field dynamic experiments were performed for berthing impact and the results were used to calibrate analysis model. Through dynamic analysis for design, berthing impact safety of old wharf structure were evaluated. In this paper the procedure and results of experiments and analysis are presented.