• Title/Summary/Keyword: Safety adminstration

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Germination Rate and Radicle Growth Inhibition in Crops by Total Petroleum Hydrocarbons (TPH) (Total petroleum hydrocarbon에 의한 작물의 발아 및 유근생장 저해)

  • Lim, Sung-Jin;Kim, Jin-Hyo;Choi, Geun-Hyoung;Kwon, Yu-Bin;Kim, Doo-Ho;Park, Byung-Jun
    • Korean Journal of Environmental Agriculture
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    • v.32 no.4
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    • pp.273-278
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    • 2013
  • BACKGROUND: Total petroleum hydrocarbons (TPH), which are main materials of soil contamination by oil, are a term used for any mixture of hydrocarbons. Korea Ministry of Environment established the maximum permissible level of TPH in farmland by 500 mg/kg, and reported that the TPH level of soil in 266 installation such as gas station, transport company, and military unit ranged from 1,356 to 55,117 mg/kg and were much higher than the maximum permissible level in 2011. METHODS AND RESULTS: To determine the effect of TPH on crops, we investigated the effect of gasoline, kerosene, and diesel on the germination and radicle growth of mainly consumed crops. The germination rates of control in investigated all crops ranged from 80.0-100%. The germination and radicle growth in majority of investigated crops were not inhibited even at 2,500 mg/L. However, germination in onion, leek, and green perilla and radicle growth in leek, rape, tomato, and green perilla were significantly inhibited by increasing concentrations of gasoline, kerosene and diesel treatment. Germination and radicle growth inhibition of green perilla by kerosene and diesel were the highest, the percent inhibition at the 500 mg/L were 100 and 98.6%, 100 and 88.2%, respectively. 50% inhibition of germination in green perilla by kerosene and diesel were 39.96 and 29.87 mg/L, and 50% inhibition of radicle growth were 52.76 and 177.96 mg/L, respectively. Conclusion(s): These results suggest the possibility that the maximum permissible level of TPH might to be established general level with exception by crops.

Determination of Niacin in Infant Formula by Solid-phase Clean-up and HPLC with Photodiode Array Detector (고체상 정제 및 HPLC/PDA에 의한 영유아식 중 나이아신의 분석)

  • Hong, Jee-Eun;Kim, Mi-Ran;Cheon, Sang-Hee;Chai, Jung-Young;Park, Eun-Ryong;Mun, Chun-Sun;Gwak, In-Shin;Kim, Ok-Hee;Lee, Kwang-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.3
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    • pp.359-363
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    • 2009
  • This study was performed to establish a rapid and simple analytical method for niacin (nicotinic acid and nicotinamide) using HPLC. A pretreatment method for the extraction and clean-up of niacin in infant formula sample and an instrumental condition for HPLC were optimized. Niacin was extracted by 5 mM hexanesulfonate with ultrasonication for 30 min. For the clean-up of the sample, the extract was applied to a HLB cartridge, and then niacin was eluted from the cartridge using 5 mL of 80% methanol after washing with 5 mL of n-hexane. The total recoveries were $83{\sim}104%$ and relative standard deviation were in the range of $1.5{\sim}3.5%$ during the extraction and clean-up process. Niacin was determined by gradient elution with sodium hexanesulfonate/methanol buffer as a mobile phase and a photodiode array detector (260 nm). It showed a high linearity between the content of niacin and the peak area ($r^2$=1.000) in the range of $0.02{\sim}10.0$ mg/L of nicotinic acid and nicotinamide. The detection limit was 0.02 mg/L (0.2 mg/kg in the sample). The method was successfully applied for the determination of niacin in infant formula. Total niacin contents were in the range of $53.5{\sim}140.3$ mg/kg.

Guidelines for Microbiological Standards of Food in Foreign Countries (제외국의 식품안전관련 미생물 정량기준 가이드라인)

  • Lee, Mi-Seon;Woo, Gun-Jo;Park, Jong-Seok;Lee, Dong-Ha;Oh, Sang-Suk
    • Journal of Food Hygiene and Safety
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    • v.19 no.3
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    • pp.140-150
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    • 2004
  • It has been recognized that international food standards should be considered for a long time. The Codex Alimentarius programme initiated in the early 1960s has received valuable background documentation from the ICMSF (International Commission on Microbiological Specification for Foods) and also from ISO(the International Organization for Standardization). There has been a considerable move towards international harmonization of standards and methods of analysis. Many foreign countries recommend the guidelines for food microbiological standards quantitatively. To complement microbiological limits and tolerance levels for permissible number of defective samples, allowances should be made for sampling and other variations in laboratory methods. It may be necessary for guidelines of domestic food microbiological standards to be established so that the domestic food standards can be harmonized with foreign food standards. Food safety related microbiological guidelines of ICMSF, EU (European Union), UK (United Kingdom), China (Hong Kong) and Japan were reviewed and shown in examples.

A Case Study on Application and Standardization of Safety Adminstration Model in Complex Style Multiflex Housing Business. (단지형 다세대주택신축사업의 안전경영모델 표준화 및 적용사례 연구)

  • Kim, Sung Soo;Yoo, Tae Gyeong;Yoo, Jin Yeol;Lee, Tae Sik
    • Journal of Korean Society of Disaster and Security
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    • v.9 no.2
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    • pp.43-52
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    • 2016
  • Notwithstanding industrial accident decrease generally, Construction industry is on the rise recently. Most accident occurs in the small scale like as multiflex housing, remodeling, neighbourhood facility more than safety supervisor appointed large scale construction site. By the size of business place, 81.6% of total accident occurs mostly in small scale site that is bellow 120 billion won and 50 manpower. This paper aimed that small scale housing company achieve a zero hazard practising and understanding the safety adminstration standar d model easily and it applied firstly after investigating the operation condition of construction site safety control in small scale company propelling the complex style multiflex housing business.

Effects of Aloe Extract on Ethanol Metabolism (알로에 추출물이 알콜대사에 미치는 영향)

  • 정정철;이주영;김미정;정진호
    • Journal of Food Hygiene and Safety
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    • v.11 no.1
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    • pp.31-34
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    • 1996
  • Aloe, being used widely as a health food and also as a traditional folk remedy for burns and constipation, contains quinone derivatives particularly in its skin. Thus, we have investigated the effect of extracts of Aloe in ethanol metabolism. The dried powder of water extract of skinned Aloe (300 mg/kg body weight given to rats by oral adminstration at 30 min prior to oral adminstration of ethanol given at a does of 4 gm/kg) and the freeze-dried Aloe gel commercial product (600 mg/kg) which was prepared after selective elimination of quinones were found not to increase the ethanol metabolism rate in vivo. This result suggested that quinones, missing from the above preparations, might be responsible for enhancing ethanol metabolism rate.

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Investigation of industries's perception on the ban of antibiotics growth promoter in commercial mixed feed (항생제 사용금지에 관한 산업체 인식조사)

  • Kim, Ki-Hyun;Kim, Kwang-Sik;Kim, Jo-Eun;Seol, Kuk-Hwan;Kim, Young-Hwa
    • Korean Journal of Agricultural Science
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    • v.42 no.4
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    • pp.389-396
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    • 2015
  • This study was performed to investigate the opinions of various related-industries on ban of antibiotics growth promoters (AGPs) in commercial mixed feed. The answers on a total of 21 questions were summarized by response number and percentage. 93% of those surveyed were in agreement of a ban of dietary AGPs. The agreement reasons were the livestock safety (61.5%), the reduction of antibiotic use (23.1%), and decrease of antibiotic-resistant bacteria (11.5%). The negative effects expected by the ban of AGPs were poor growth performance (44.2%), elevated disease emergence (31.4%), increasing the feed cost (18.6%), and quality degradation of livestock (5.8%). As the efficient plans for decline of AGPs use, the feeding environment improvement was the highest with 43%, and farmer training and the consolidation inspection of residual substance on antibiotics in livestock product was 27.9% and 22.1%, respectively. 46.5% of respondent are considering the modification of feed spec and 39.5% of those surveyed have staged a modified feed spec. In conclusion, livestock related-industries approve a ban of AGPs, and they assert that the policy support, improvement of management and environment in the farm, providing technology from related-industries are multiply essential for a stable settlement of a ban policy of AGPs.

The Comparative Study on Post-Marketing Surveillance System for Pharmaceuticals (의약품의 시판후 조사제도 비교연구)

  • Kim, In-Beom;Kim, Hong-Jin;Sohn, Uy-Dong
    • YAKHAK HOEJI
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    • v.50 no.3
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    • pp.145-153
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    • 2006
  • The adverse events which do not appear in the approval process tend to occur more frequently at the early stage of the use. Therefore new drugs, drugs with different active substances or routes of administration, or drugs with explicitly different efficacy added are particularly chosen for re-examination, and go through a study, which is conducted on 600 to 3,000 subjects over 4 to 6 years. Since the re-examination system was implemented in January 1995, 880 drug products have been designated as the subject of re-examination and among them 194 drugs have been completed their re-examination as of until March 2005. Post Marketing Surveillance to insure drug safety should be correlated with re-examination of new drug, re-evaluation of drug, and adverse event monitoring system. And the first labeling change should reflect all information collected for a defined period of time after the marketing authorization is granted. Furthermore centralized management through spontaneous reporting system of adverse event for whole period of time would be the most desirable type of system.

AHP Model and a Case Study for Determinants of Overseas Factory Location for Sewing and Apparel Products Industry (AHP를 이용한 봉제·의류제조업의 해외입지선정 모형 및 적용 사례)

  • Kim, Joo-In;Baek, Nakki;Lee, Jae Kwang
    • Journal of the Korea Safety Management & Science
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    • v.16 no.3
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    • pp.377-388
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    • 2014
  • There have been a lot of studies about overseas factory location in order to meet various needs of industries according to the international economic developments. However, most of the studies were written about generic theory for general industries or mainly concerned to high capital industries. This study is focusing on the sewing and apparel industries which represent labor intensive and small-medium type of enterprises. For this study, AHP(Analytic Hierarchy Process) methods were applied to make proper analysis after wide range of survey to clarify determinants which provide a guidance for overseas factory location. As a result of the analytical researches done in the thesis the most important which should be taken consideration while determining of overseas factory location for sewing and apparel products industry are as follows - economic factors(0.569), geographic factors(0.171), social and cultural factors(0.157), regulations and institutional factors(0.103). In the last, S company is examined for example to show how this determinants have practically been applied.

Insecticidal activity of Diamondback Moth, Plutella xylostella against Bacillus thuringiensis and Neem oil (Bacillus thuringiensis와 Neem oil에 대한 배추좀나방의 살충활성)

  • Cho, Min-Su;Choi, Su-Yeon;Kim, Tae-Whan;Park, Chan;Kim, Dam-A;Kim, Young-Rim;Oh, Se-Mun;Kim, Sung-Woo;Youn, Young-Nam;Yu, Yong-Man
    • The Korean Journal of Pesticide Science
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    • v.13 no.4
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    • pp.315-324
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    • 2009
  • For the environmental friendly management of diamondback moth, Plutella xylostella (L.), Bacillus thuringiensis subsp. kurstaki ($30{\times}10^8\;cfu/mg$) and neem oil (0.5% azadirachtin) were used as green control agencies with mixed and alternative treatments on the chinese cabbage. When Bacillus thuringiensis subsp. kurstaki was applied to 1st and 2nd larva of P. xylostella with recommended concentration, their mortalities were reached to 100% by 2 days after treatment. In case of azadirachtin, its effect of mortality was continued for 7 days, and reached to 100% mortality. $LC_{50}$ values of Bacillus thuringiensis subsp. kurstaki and azadirachtin against 1st, 2nd, 3rd and 4th larva of P. xylostella were $2.8{\times}10^4$, $3.1{\times}10^4$, $3.4{\times}10^4$ and $1.5{\times}10^5\;cfu/ml$, and 2.7, 3.9, 4.7 and 7.1 ppm, respectively. The number of laid eggs of P. xylostella was reduced to 57.5 at 25 ppm of azadirachtin compared with control treatment. The hatch ratio was not significantly different with Bacillus thuringiensis subsp. kurstaki treatment in comparison with control treatment. However, when azadirachtin was applied, their hatch ratio were reduced to 25.8 and 45.4% at 25 and 50 ppm, respectively. On the other hand, emergence rate of eggs was not different with Bacillus thuringiensis subsp. kurstaki treatment, but 45.4% was shown in azadirachtin treatment with 50 ppm in comparison with control. When the mixture with Bacillus thuringiensis subsp. kurstaki and azadirachtin was applied to adults of P. xylostella, their mortality was higher than Bacillus thuringiensis subsp. kurstaki treatment only. These results are supposed that the mixture of Bacillus thuringiensis subsp. kurstaki and azadirachtin might be used as green control agents for reducing the demage of diamondback moth in the Chinse cabbage.