• 한국식품위생안전성학회지
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• 제15권4호
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• pp.277-281
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• 2000

한천은 비교적 풍부한 수산자원의 하나이나 그 가공 수준은 매우 미약하여 상당수가 폐기되고 있다. 한천의 이용률과 부가가치를 높이기 위하여 한천올리고당의 미생물학적 활성에 관한 연구를 수행하였다. 식품 부패 및 식중독균에 대한 억제 효과는 0.4% 한천올리고당은 첨가한 경우 포노상구균과 대장균 O157:H7에 대하여 항균활성을 나타내었다. 한천올리고당은 pH의 변화에 매우 안정하여 pH는 항균활성에 영향을 주지 않았다. 또한 가압멸균할 경우 항균효과가 현저히 증가함을 보였다 한천올리고당의 가공 적성을 알아본 결과 아미노산 중 alanine, lysine, glycine, phenylalanine을 혼합하면 항균 활성이 증가함을 알 수 있었다

• 한국식품위생안전성학회지
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• 제10권3호
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• pp.133-138
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• 1995

In vitro antimutagenic activity of methanol extract from brrwn rice and its physico-chemical characteristics were investigated using Salmonella typhimurium reversion assay and SOS chromotest. Methanol extracts of brown rice were not mutagenic compared with direct and indirect, mutagenicities of 4NQO (4-nitroquinoline oxide), 2NF(2-nitrofluorene), Trp-p-1(3-Amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole), and Trp-p-2(3-Amino-1-methy-5H-pyrido-[4,3-b]indole). Antimutagenic activity against the indirect mutagenicties induced by Trp-p-1, Trp-p-2 and AFB1 (aflatoxin B1) was found in methanol extract. Even though antimutagenic activity showed dose-dependent, it remained constant at inhibition rate ranging 60~90% when the concentration was abov 3mg/plate in the S. typhimurium reversion assay and 0.2~0.6 mg/assay in the SOS chromotest. The antimutagenic activity of the methanol extracts was stable at various pH (2, 7 and 10), temperatures (60, 80 and 10$0^{\circ}C$)and heation times (2, 4, 6, 8, 10 min at 10$0^{\circ}C$).

• Nuclear Engineering and Technology
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• 제50권1호
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• pp.165-169
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• 2018

An assessment for determining N-16 activity concentrations during the operation condition of Bangladesh Atomic Energy Commission TRIGA Research Reactor was performed employing several governing equations. The radionuclide N-16 is a high energy (6.13 MeV) gamma emitter which is predominately created by the fast neutron interaction with O-16 present in the reactor core water. During reactor operation at different power level, the concentration of N-16 at the reactor bay region may increase causing radiation risk to the reactor operating personnel or the general public. Concerning the safety of the research reactor, the present study deals with the estimation of N-16 activity concentrations in the regions of reactor core, reactor tank, and reactor bay at different reactor power levels under natural convection cooling mode. The estimated N-16 activity concentration values with 500 kW reactor power at the reactor core region was $7.40{\times}10^5Bq/cm^3$ and at the bay region was $3.39{\times}10^5Bq/cm^3$. At 3 MW reactor power with active forced convection cooling mode, the N-16 activity concentration in the decay tank exit water was also determined, and the value was $4.14{\times}10^{-1}Bq/cm^3$.

• 한국산업보건학회지
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• 제22권2호
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• pp.91-99
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• 2012

Airborne chlorpyrifos concentrations in formulation workplaces have not been determined in Korea. The aim of the study was to evaluate chlorpyrifos concentrations of air in a formulation workplace and recognize the RBC cholinesterase activities for the formulation workers. 30 air samples (personal or area sampling) were collected and bood samples from 10 workers were collected for RBC chlorinesterase (RBC AChE) activity in a factory on May 2008. Air samples were collected by the National Institute for Occupational Safety and Health (NIOSH) method and were analyzed by GC-MS. Airborne chlorpyrifos concentrations ranged from 0.003 to $12.90mg/m^3$ and geometric mean (GM) was $0.15\;mg/m^3.$ Compared to Korean Occupational Exposure Limit (KOEL) of 0.1 (2011) or $0.2\;mg/m^3$ (2008), at 95% confidence, airborne concentrations exceeded the KOEL 69.7% or 56.1% of the time or less, indicating that this concentration level was unacceptable according to exposure assessment using a LogNorm2$^{(R)}$. Since the workers were continually at work on the organophosphate or carbamate pesticides formulation, individual baseline for RBC AChE activity was not determined. As the results of comparison with reference average value of RBC AChE activity, it was found that a worker was below 70% RBC AChE activity and five workers were abnormal.

• Human Ecology Research
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• 제59권4호
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• pp.433-448
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• 2021

The purpose of this study was to analyze two subject competencies (practical problem-solving capability and independent life capability) reflected in the activity tasks included in the 'home life and safety' area of 12 middle school technology-home economics textbooks in accordance with the 2015 revised curriculum. The analysis criteria were sub-elements of two subject competencies. Seven sub-elements were derived from each competency. Frequency analysis was performed to determine how often the sub-elements were reflected in the activity tasks. The results were as follows. First, with regard to the sub-elements of 'practical problem-solving capability', 'value judgment' was reflected most frequently in the activity tasks followed by 'exemplification of solution', 'logical thinking', 'critical thinking', 'decision-making', 'practical reasoning', and 'evaluation of solutions'. Secondly, the sub-elements of 'independent life capability' were unevenly distributed in the activity tasks. The 'capability to perform conscious living' was reflected most frequently followed by 'development and self-identity', 'time, money, and leisure management', and 'reasonable consumption and resource utilization'. For teachers wanting to teach activity-oriented classes and student participatory classes, the results pinpoint the materials necessary to develop learners' subject competencies by using textbooks from different publishing companies.

• Biomolecules & Therapeutics
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• 제1권2호
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• pp.137-142
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• 1993

The possible tumor-promoting activities of sodium chloride (NaCl) and dimethyl itaconate (DMI), one of the quinone reductase inducers, were examined on stomach of male Wistar rats treated with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Administrations of NaCl and DMI after the initiation by MNNG resulted in various sized masses in the rat forestomach. Histopathologic studies showed that the combination of NaCl and DMI made an enhancing effect on the MNNG-induced carcinogenesis, resulting in papilloma in 5 weeks and squamous cell carcinoma in 20 weeks in submucosal area of forestomach. We also used an in vivo shortterm method for evaluating possible tumor-promoting activity with ornithine decarboxylase (ODC) as a marker. The markable inductions of the ODC activities by MNNG, NaCl, and DMI were found in the pyloric mucosa of rat stomach in time-dependent manners. A single administration of MNNG induced ODC activity up to 288 pmol $CO_2$/hr/mg protein at 24 hr after the administration. NaCl caused induction of ODC with a maximum of 179 pmol $CO_2$/hr/mg protein at 8 hr after the administration. ODC was induced up to 539 pmol $CO_2$/hr/mg protein at 16 hr after the administration of DMI. Additional treatment of NaCl and NaCl plus DMl caused 2 fold and 7 fold increases, respectively, in the ODC activity of the MNNG-alone group at 24 hr after the administration. These results suggest that NaCl and DMI have promoting activities in the rat gastric carcinogenesis initiated by MNNG.

• Journal of the Korean Wood Science and Technology
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• 제45권1호
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• pp.116-125
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• 2017

본 연구는 폭쇄처리된 신갈나무로부터 유래된 열수추출물의 안전성 및 항산화성 효과에 대해 검토하였다. 안전성 시험으로는 세포독성실험, 경구투여 독성시험이 실시되었으며, 신갈나무 폭쇄처리 열수추출물의 항산화성 유무를 확인하기 위해서 실험동물은 일본 Air Logistics사의 4주령 B6C3F1 숫컷 생쥐로 다섯 군(1군 10마리)으로 나누어서 실험을 하였다. 신갈나무 폭쇄처리 열수추출물의 세포독성 및 경구투여 독성시험의 결과로 독성은 관찰되지 않았으며, 신갈나무 폭쇄처리 열수추출물의 투여군에서 과산화물분해효소의 활성이 29% 이상 증가하여 과산화물분해효소의 활성이 유의적으로 인정되었다. 따라서 신갈나무 폭쇄처리 열수추출물은 뛰어난 안전성과 항산화성이 있음을 확인하였다.

• Safety and Health at Work
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• 제10권4호
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• pp.527-530
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• 2019

The increasing prevalence of inactivity and obesity, along with aging, has implications on work capacity of labor force. This study reports the relationships between activity level and BMI by age with objectively measured physical workload. Data were examined from a sample of 19 481 Finnish employees using an estimate of minute-to-minute oxygen consumption based on R-R interval recordings. The mean estimated %VO₂max during the working day was 12.1 (±3.6) and 15.1 (±4.5)% for men and women, respectively. Based on a linear model, the mean %VO₂max increased by 1.5%-unit per 10-year increase in age, by 2.1%-unit per 5 kg/㎡ increase in BMI, and decreased by 1.6%-unit if improving physical activity class by two (p < 0.001 for all). Overweight and obesity, together with inactivity, notably increases workload throughout the career, even though at young adulthood, the daily workload is almost the same for each person regardless of the BMI, activity level, or gender. This study highlights the importance of regular physical activity and normal weight in protecting the worker from excessive physical (cardiovascular) workload during the whole working career.

• 한국안전학회지
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• 제20권4호
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• pp.122-129
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• 2005

With Zohar(1980)'s research on safety climate and industrial safety, occupational safety and health literatures begin to emphasize the influence of organizational context. Based on this research trend, this paper tried to review the relationship between individual/ organizational factors and occupational accidents. Based on the responses from 294 manufacturing workers, this paper reviewed the relationships among safety climates, safety performance, and age. The results of statistical analysis showed that all safety climate factors have affirmative effects on safety participation and safety attitudes negative effect on accident number, and job load affirmative effect on accident number. Job load and management commitment showed interactive effects on accident number with age.

• 한국산학기술학회논문지
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• 제17권11호
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• pp.332-339
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• 2016

본 연구는 수술실 간호사의 환자안전인식과 안전관리활동을 분석한 후 상관관계를 파악한 연구이다. 목적은 수술환자의 안전관리활동 수행정도를 향상시키기 위한 교육 프로그램 개발과 안전한 수술실 환경 조성을 위한 기초자료를 제공하고자 함이다. 연구대상은 대구광역시와 경상북도에 소재한 8개 종합병원 수술실 간호사 161명이었고, 자료 분석은 SPSS 21.0 program을 이용하여 t-test, ANOVA, Correlation coefficient를 실시하였으며 사후분석으로 Scheffe's test를 실시하였다. 그 결과 수술실 간호사의 환자안전인식 점수는 5점 만점에 3.33점이었으며, 환자안전관리활동 점수는 5점 만점에 4.28점이었다. 대상자의 일반적 특성과 근무특성에 따른 환자안전인식을 분석한 결과 수술실 간호사의 근무시간에 따라서 환자안전인식이 차이가 있었으며 안전관리활동은 병상 수와 인증평가 준비 유무에 따라 차이가 있었다. 수술실 간호사의 환자안전에 대한 인식과 안전관리활동 간의 관계를 파악한 결과 유의한 양의 상관관계가 있어 환자안전인식이 높을수록 안전관리활동 정도가 높은 것으로 나타났다. 결론적으로 안전관리활동을 향상시키기 위해서는 환자안전에 대한 인식을 증가시키는 것이 필요하며, 환자안전에 대한 인식을 증가시키기 위해서는 직원 간의 개방적인 논의와 환자안전에 대한 병원의 지원 및 주기적인 교육과 같은 중재가 필요하다.