• Journal of Positioning, Navigation, and Timing
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• v.5 no.3
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• pp.145-156
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• 2016

A variety of methods for indoor positioning systems have been underway to ensure the safety of emergency rescuers who are working in dangerous situations such as fire fighters. However, since most systems display locations of rescue workers in two-dimension (2D)-based maps, it is difficult for a commander located in the outside to recognize locations of rescuers inside the building intuitively. An augmented reality (AR)-based indoor positioning monitoring system can display locations of rescuer inside the building that can be seen by commanders to help intuitive recognition of positioning. To monitor AR-based indoor positioning, it is necessary to have an estimation technique of line of sight vector of observers. In the present study, an estimation technique of a line of sight vector using ultra-wide band tranceiver installed inside the indoor to trace locations is presented.

• Environmental Analysis Health and Toxicology
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• v.24 no.1
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• pp.71-77
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• 2009

Adenoviral vector(AdV) has been the most widely used viral vector for delivering an exogenous therapeutic gene to human. As of this date, more clinical trials utilize recombinant AdV to treat cancer and monogenic inherited disease as well as vaccine applications. However, the number of clinical trials had dropped markedly following the tragic death of a patient ongoing an AdV therapy for the treatment of an ornithine transcarbamylase deficiency(OTCD). This review is an attempt to provide the information on toxicity generated by AdVmediated gene transfer. It would serve as a sobering reality to researchers and clinicians exploring the use of AdV, as to the complications involved in human application.

• Tunnel and Underground Space
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• v.29 no.5
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• pp.332-345
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• 2019

Maximum dip vector of individual joint plane, which can be uniquely defined on the hemispherical projection plane, has been established by considering its dip and dip direction. A new stereographic projection method for the rock slope analysis which employs the maximum dip vector can intuitively predict the failure modes of rock slope. Since the maximum dip vector is uniquely projected on the maximum dip point of the great circle, the sliding direction of discontinuity plane can be recognized directly. By utilizing the maximum dip vector of discontinuity both the plane sliding and toppling directions of corresponding blocks can be discerned intuitively. Especially, by allocating the area of high dip maximum dip vector which can form the flanks of sliding block the potentiality for the formation of virtual sliding block has been estimated. Also, the potentiality of forming the triangular-sectioned sliding block has been determined by considering the dip angle of joint plane the dip direction of which is nearly opposite to that of the slope face. Safety factors of the different-shaped blocks of triangular section has been estimated and compared to the safety factor of the most hazardous block of rectangular section. For the wedge analysis the direction of crossline of two intersecting joint planes, which has same attribute of the maximum dip vector, is used so that wedge failures zone can be superimposed on the stereographic projection surface in which plane and toppling failure areas are already lineated. In addition the maximum dip vector zone of wedge top face has been delineated to extract the wedge top face-forming joint planes the orientation of which provides the vital information for the analysis of mechanical behavior of wedge block.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.285-286
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• 2016

We aim to propose the prediction modeling method of ship's position with extracting ship's trajectory model through pattern recognition based on the data that are being collected in VTS centers at real time. Support Vector Machine algorithm was used for data modeling. The optimal parameters are calculated with k-fold cross validation and grid search. We expect that the proposed modeling method could support VTS operators' decision making in case of complex encountering traffic situations.

• Computers and Concrete
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• v.20 no.5
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• pp.555-562
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• 2017

The accuracy and integrity of stress data acquired by bridge heath monitoring system is of significant importance for bridge safety assessment. However, the missing and abnormal data are inevitably existed in a realistic monitoring system. This paper presents a data reconstruction approach for bridge heath monitoring based on the wavelet multi-resolution analysis and support vector machine (SVM). The proposed method has been applied for data imputation based on the recorded data by the structural health monitoring (SHM) system instrumented on a prestressed concrete cable-stayed bridge. The effectiveness and accuracy of the proposed wavelet-based SVM prediction method is examined by comparing with the traditional autoregression moving average (ARMA) method and SVM prediction method without wavelet multi-resolution analysis in accordance with the prediction errors. The data reconstruction analysis based on 5-day and 1-day continuous stress history data with obvious preternatural signals is performed to examine the effect of sample size on the accuracy of data reconstruction. The results indicate that the proposed data reconstruction approach based on wavelet multi-resolution analysis and SVM is an effective tool for missing data imputation or preternatural signal replacement, which can serve as a solid foundation for the purpose of accurately evaluating the safety of bridge structures.

• Nuclear Engineering and Technology
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• v.50 no.8
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• pp.1306-1313
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• 2018

The randomness and incipient nature of certain faults in reactor systems warrant a robust and dynamic detection mechanism. Existing models and methods for fault diagnosis using different mathematical/statistical inferences lack incipient and novel faults detection capability. To this end, we propose a fault diagnosis method that utilizes the flexibility of data-driven Support Vector Machine (SVM) for component-level fault diagnosis. The technique integrates separately-built, separately-trained, specialized SVM modules capable of component-level fault diagnosis into a coherent intelligent system, with each SVM module monitoring sub-units of the reactor coolant system. To evaluate the model, marginal faults selected from the failure mode and effect analysis (FMEA) are simulated in the steam generator and pressure boundary of the Chinese CNP300 PWR (Qinshan I NPP) reactor coolant system, using a best-estimate thermal-hydraulic code, RELAP5/SCDAP Mod4.0. Multiclass SVM model is trained with component level parameters that represent the steady state and selected faults in the components. For optimization purposes, we considered and compared the performances of different multiclass models in MATLAB, using different coding matrices, as well as different kernel functions on the representative data derived from the simulation of Qinshan I NPP. An optimum predictive model - the Error Correcting Output Code (ECOC) with TenaryComplete coding matrix - was obtained from experiments, and utilized to diagnose the incipient faults. Some of the important diagnostic results and heuristic model evaluation methods are presented in this paper.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.86-86
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• 2003

Gene therapy is a medical intervention based on modification of the genetic material of living cells. Gene transfer usually conducted using bacterial plasmid DNA and/or virus vector to express a specific protein. Gene transfer medicinal products classified as naked nucleic acid, complexed nucleic acid or non-viral vectors, viral vector, and genetically modified cells according to biological origin.(omitted)

• Journal of Food Hygiene and Safety
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• v.14 no.4
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• pp.415-421
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• 1999

The flavin-containing monooxygenases (FMOs) (EC 1.14. 13.8) are NADPH-dependent flavoenzymes that catalyze oxidation of soft nucleophilic heteroatom centers in a range of structurally diverse compounds including foods, drugs, pesticides, and other xenobiotics. In humans, FMOl appears to be the predominant form expressed in human fetal liver. cDNA-expressed human FMO and human liver microsomal FMO have been observed to N- and S-oxy-genate nucleophilic nitrogen- and sulfur-containing drugs and chemicals, respectively. In the present study, FMOl can be expressed in the baculovirus expression vector system at level of 2.68 nmol FMOl/mg of membrane protein. This isoform was examined for its capacity to metabolize methimazole to its S-oxide using thiocholine assay. Kinetic studies of its S-oxide by recombinant human FMO1 result in Km of 7.66 $\mu$M and Vmax of 17.79 nmol/min/mg protein.

• Journal of the Korean Society of Safety
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• v.17 no.2
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• pp.32-38
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• 2002

In this paper, a new approach for the SynRM(Synchronous Reluctance Motor) control which ensures producing MTPA(Maximum Torque per Ampere) over the entire field weakening region is presented. In addition, this paper presents a speed sensorless control scheme of SynRM using flux observer. Also, by adjusting the base speed for the field weakening operation according to the flux level, the current and voltage limit, the smooth and precise transition into the field weakening operation can be achieved. The validity of the proposed scheme is verified through simulation.

• Proceedings of the KSR Conference
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• 2010.06a
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• pp.213-219
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• 2010

MCU(Micro Controller Unit) used for the automobiles has been required for improving of the safety and high reliability. Also, the necessity of high performance MCU equipped with high fuel-efficiency has been risen according to increased requests of high fuel-efficiency and improving the occupants safety with the development of intelligent vehicles and future vehicles. The MPC5554 32-bit embedded controller, made by Freescale Semiconductor, specialized in the part of the power train provides the high reliability, fast interrupt process and real-time control. In This paper, the investigation on IPMSM using MPC5554 has been performed. Also SVPWM(Space Vector Pulse Width Modulation) is implemented to the servo system.